-
1
-
-
33744831158
-
Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor
-
Aoudjit L, Potapov A, Takano T. Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. Am J Physiol Renal Physiol 290: F1534-F1542, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Aoudjit, L.1
Potapov, A.2
Takano, T.3
-
3
-
-
0038554077
-
Biology of the p21-activated kinases
-
Bokoch GM. Biology of the p21-activated kinases. Annu Rev Biochem 72: 743-781, 2003.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 743-781
-
-
Bokoch, G.M.1
-
4
-
-
0032478605
-
A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids
-
Bokoch GM, Reilly AM, Daniels RH, King CC, Olivera A, Spiegel S, Knaus UG. A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids. J Biol Chem 273: 8137-8144, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 8137-8144
-
-
Bokoch, G.M.1
Reilly, A.M.2
Daniels, R.H.3
King, C.C.4
Olivera, A.5
Spiegel, S.6
Knaus, U.G.7
-
5
-
-
0029911521
-
Interaction of the Nck adapter protein with p21-activated kinase (PAK1)
-
Bokoch GM, Wang Y, Bohl BP, Sells MA, Quilliam LA, Knaus UG. Interaction of the Nck adapter protein with p21-activated kinase (PAK1). J Biol Chem 271: 25746-25749, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 25746-25749
-
-
Bokoch, G.M.1
Wang, Y.2
Bohl, B.P.3
Sells, M.A.4
Quilliam, L.A.5
Knaus, U.G.6
-
6
-
-
44949176114
-
Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms
-
Coniglio SJ, Zavarella S, Symons MH. Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Mol Cell Biol 28: 4162-4172, 2008.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4162-4172
-
-
Coniglio, S.J.1
Zavarella, S.2
Symons, M.H.3
-
7
-
-
0032472918
-
Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells
-
Daniels RH, Hall PS, Bokoch GM. Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells. EMBO J 17: 754-764, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 754-764
-
-
Daniels, R.H.1
Hall, P.S.2
Bokoch, G.M.3
-
8
-
-
23044467856
-
PDK2: The missing piece in the receptor tyrosine kinase signaling pathway puzzle
-
Dong LQ, Liu F. PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle. Am J Physiol Endocrinol Metab 289: E187-E196, 2005.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Dong, L.Q.1
Liu, F.2
-
9
-
-
0035126234
-
Podocytes respond to mechanical stress in vitro
-
Endlich N, Kress KR, Reiser J, Uttenweiler D, Kriz W, Mundel P, Endlich K. Podocytes respond to mechanical stress in vitro. J Am Soc Nephrol 12: 413-422, 2001.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 413-422
-
-
Endlich, N.1
Kress, K.R.2
Reiser, J.3
Uttenweiler, D.4
Kriz, W.5
Mundel, P.6
Endlich, K.7
-
10
-
-
34250305530
-
LIM kinase and slingshot are critical for neurite extension
-
Endo M, Ohashi K, Mizuno K. LIM kinase and slingshot are critical for neurite extension. J Biol Chem 282: 13692-13702, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 13692-13702
-
-
Endo, M.1
Ohashi, K.2
Mizuno, K.3
-
11
-
-
0032561355
-
Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation
-
Frost JA, Khokhlatchev A, Stippec S, White MA, Cobb MH. Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation. J Biol Chem 273: 28191-28198, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 28191-28198
-
-
Frost, J.A.1
Khokhlatchev, A.2
Stippec, S.3
White, M.A.4
Cobb, M.H.5
-
12
-
-
37549036286
-
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization
-
Garg P, Verma R, Nihalani D, Johnstone DB, Holzman LB. Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol Cell Biol 27: 8698-8712, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8698-8712
-
-
Garg, P.1
Verma, R.2
Nihalani, D.3
Johnstone, D.B.4
Holzman, L.B.5
-
13
-
-
58449096160
-
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms
-
Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S. An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms. PLoS One 4: e4194, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Hirose, T.1
Satoh, D.2
Kurihara, H.3
Kusaka, C.4
Hirose, H.5
Akimoto, K.6
Matsusaka, T.7
Ichikawa, I.8
Noda, T.9
Ohno, S.10
-
15
-
-
33645746950
-
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
-
Jones N, Blasutig IM, Eremina V, Ruston JM, Bladt F, Li H, Huang H, Larose L, Li SS, Takano T, Quaggin SE, Pawson T. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 440: 818-823, 2006.
-
(2006)
Nature
, vol.440
, pp. 818-823
-
-
Jones, N.1
Blasutig, I.M.2
Eremina, V.3
Ruston, J.M.4
Bladt, F.5
Li, H.6
Huang, H.7
Larose, L.8
Li, S.S.9
Takano, T.10
Quaggin, S.E.11
Pawson, T.12
-
16
-
-
67649690129
-
Nck proteins maintain the adult glomerular filtration barrier
-
Jones N, New LA, Fortino MA, Eremina V, Ruston J, Blasutig IM, Aoudjit L, Zou Y, Liu X, Yu GL, Takano T, Quaggin SE, Pawson T. Nck proteins maintain the adult glomerular filtration barrier. J Am Soc Nephrol 20: 1533-1543, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1533-1543
-
-
Jones, N.1
New, L.A.2
Fortino, M.A.3
Eremina, V.4
Ruston, J.5
Blasutig, I.M.6
Aoudjit, L.7
Zou, Y.8
Liu, X.9
Yu, G.L.10
Takano, T.11
Quaggin, S.E.12
Pawson, T.13
-
17
-
-
0037117478
-
Modulation of protein translation by Nck-1
-
Kebache S, Zuo D, Chevet E, Larose L. Modulation of protein translation by Nck-1. Proc Natl Acad Sci USA 99: 5406-5411, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5406-5411
-
-
Kebache, S.1
Zuo, D.2
Chevet, E.3
Larose, L.4
-
18
-
-
0035720564
-
Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat
-
Kim YH, Goyal M, Kurnit D, Wharram B, Wiggins J, Holzman L, Kershaw D, Wiggins R. Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat. Kidney Int 60: 957-968, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 957-968
-
-
Kim, Y.H.1
Goyal, M.2
Kurnit, D.3
Wharram, B.4
Wiggins, J.5
Holzman, L.6
Kershaw, D.7
Wiggins, R.8
-
19
-
-
0034731505
-
p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1)
-
King CC, Gardiner EM, Zenke FT, Bohl BP, Newton AC, Hemmings BA, Bokoch GM. p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1). J Biol Chem 275: 41201-41209, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 41201-41209
-
-
King, C.C.1
Gardiner, E.M.2
Zenke, F.T.3
Bohl, B.P.4
Newton, A.C.5
Hemmings, B.A.6
Bokoch, G.M.7
-
20
-
-
23844448360
-
Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells
-
Kurokawa K, Nakamura T, Aoki K, Matsuda M. Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells. Biochem Soc Trans 33: 631-634, 2005.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 631-634
-
-
Kurokawa, K.1
Nakamura, T.2
Aoki, K.3
Matsuda, M.4
-
21
-
-
44449097488
-
On the Rho'd: The regulation of membrane protrusions by Rho-GTPases
-
Ladwein M, Rottner K. On the Rho'd: the regulation of membrane protrusions by Rho-GTPases. FEBS Lett 582: 2066-2074, 2008.
-
(2008)
FEBS Lett
, vol.582
, pp. 2066-2074
-
-
Ladwein, M.1
Rottner, K.2
-
22
-
-
0034604338
-
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
-
Lei M, Lu W, Meng W, Parrini MC, Eck MJ, Mayer BJ, Harrison SC. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell 102: 387-397, 2000.
-
(2000)
Cell
, vol.102
, pp. 387-397
-
-
Lei, M.1
Lu, W.2
Meng, W.3
Parrini, M.C.4
Eck, M.J.5
Mayer, B.J.6
Harrison, S.C.7
-
23
-
-
9644273952
-
SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin
-
Li H, Lemay S, Aoudjit L, Kawachi H, Takano T. SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin. J Am Soc Nephrol 15: 3006-3015, 2004
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 3006-3015
-
-
Li, H.1
Lemay, S.2
Aoudjit, L.3
Kawachi, H.4
Takano, T.5
-
24
-
-
33748294311
-
Rat nephrin modulates cell morphology via the adaptor protein Nck
-
Li H, Zhu J, Aoudjit L, Latreille M, Kawachi H, Larose L, Takano T. Rat nephrin modulates cell morphology via the adaptor protein Nck. Biochem Biophys Res Commun 349: 310-316, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 310-316
-
-
Li, H.1
Zhu, J.2
Aoudjit, L.3
Latreille, M.4
Kawachi, H.5
Larose, L.6
Takano, T.7
-
25
-
-
33748294311
-
Rat nephrin modulates cell morphology via the adaptor protein Nck
-
Li H, Zhu J, Aoudjit L, Latreille M, Kawachi H, Larose L, Takano T. Rat nephrin modulates cell morphology via the adaptor protein Nck. Biochem Biophys Res Commun 349: 310-316, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 310-316
-
-
Li, H.1
Zhu, J.2
Aoudjit, L.3
Latreille, M.4
Kawachi, H.5
Larose, L.6
Takano, T.7
-
26
-
-
0033590651
-
Mechanism of activation of Pak1 kinase by membrane localization
-
Lu W, Mayer BJ. Mechanism of activation of Pak1 kinase by membrane localization. Oncogene 18: 797-806, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 797-806
-
-
Lu, W.1
Mayer, B.J.2
-
27
-
-
0031017477
-
A casein kinase I activity is constitutively associated with Nck
-
Lussier G, Larose L. A casein kinase I activity is constitutively associated with Nck. J Biol Chem 272: 2688-2694, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 2688-2694
-
-
Lussier, G.1
Larose, L.2
-
28
-
-
33847791698
-
The podocyte in health and disease: Insights from the mouse
-
Michaud JL, Kennedy CR. The podocyte in health and disease: insights from the mouse. Clin Sci (Lond) 112: 325-335, 2007.
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 325-335
-
-
Michaud, J.L.1
Kennedy, C.R.2
-
29
-
-
6344276685
-
Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization
-
Moeller MJ, Soofi A, Braun GS, Li X, Watzl C, Kriz W, Holzman LB. Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J 23: 3769-3779, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 3769-3779
-
-
Moeller, M.J.1
Soofi, A.2
Braun, G.S.3
Li, X.4
Watzl, C.5
Kriz, W.6
Holzman, L.B.7
-
30
-
-
0031563832
-
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
-
Mundel P, Reiser J, Zuniga Mejia Borja A, Pavenstadt H, Davidson GR, Kriz W, Zeller R. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp Cell Res 236: 248-258, 1997.
-
(1997)
Exp Cell Res
, vol.236
, pp. 248-258
-
-
Mundel, P.1
Reiser, J.2
Zuniga Mejia Borja, A.3
Pavenstadt, H.4
Davidson, G.R.5
Kriz, W.6
Zeller, R.7
-
31
-
-
60549083305
-
Inducible rodent models of acquired podocyte diseases
-
Pippin JW, Brinkkoetter PT, Cormack-Aboud FC, Durvasula RV, Hauser PV, Kowalewska J, Krofft RD, Logar CM, Marshall CB, Ohse T, Shankland SJ. Inducible rodent models of acquired podocyte diseases. Am J Physiol Renal Physiol 296: F213-F229, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Pippin, J.W.1
Brinkkoetter, P.T.2
Cormack-Aboud, F.C.3
Durvasula, R.V.4
Hauser, P.V.5
Kowalewska, J.6
Krofft, R.D.7
Logar, C.M.8
Marshall, C.B.9
Ohse, T.10
Shankland, S.J.11
-
32
-
-
34447517646
-
Specificity profiling of Pak kinases allows identification of novel phosphorylation sites
-
Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. J Biol Chem 282: 15667-15678, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 15667-15678
-
-
Rennefahrt, U.E.1
Deacon, S.W.2
Parker, S.A.3
Devarajan, K.4
Beeser, A.5
Chernoff, J.6
Knapp, S.7
Turk, B.E.8
Peterson, J.R.9
-
33
-
-
0035955441
-
Cdc42-independent activation and translocation of the cytostatic p21-activated protein kinase gamma-PAK by sphingosine
-
Roig J, Tuazon PT, Traugh JA. Cdc42-independent activation and translocation of the cytostatic p21-activated protein kinase gamma-PAK by sphingosine. FEBS Lett 507: 195-199, 2001.
-
(2001)
FEBS Lett
, vol.507
, pp. 195-199
-
-
Roig, J.1
Tuazon, P.T.2
Traugh, J.A.3
-
34
-
-
0031105660
-
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
-
Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol 7: 202-210, 1997.
-
(1997)
Curr Biol
, vol.7
, pp. 202-210
-
-
Sells, M.A.1
Knaus, U.G.2
Bagrodia, S.3
Ambrose, D.M.4
Bokoch, G.M.5
Chernoff, J.6
-
35
-
-
59549099037
-
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics
-
Smith SD, Jaffer ZM, Chernoff J, Ridley AJ. PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J Cell Sci 121: 3729-3736, 2008.
-
(2008)
J Cell Sci
, vol.121
, pp. 3729-3736
-
-
Smith, S.D.1
Jaffer, Z.M.2
Chernoff, J.3
Ridley, A.J.4
-
36
-
-
0030811528
-
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts
-
Tang Y, Chen Z, Ambrose D, Liu J, Gibbs JB, Chernoff J, Field J. Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol Cell Biol 17: 4454-4464, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4454-4464
-
-
Tang, Y.1
Chen, Z.2
Ambrose, D.3
Liu, J.4
Gibbs, J.B.5
Chernoff, J.6
Field, J.7
-
37
-
-
41449115008
-
Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis
-
Uchida K, Suzuki K, Iwamoto M, Kawachi H, Ohno M, Horita S, Nitta K. Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis. Kidney Int 73: 926-932, 2008.
-
(2008)
Kidney Int
, vol.73
, pp. 926-932
-
-
Uchida, K.1
Suzuki, K.2
Iwamoto, M.3
Kawachi, H.4
Ohno, M.5
Horita, S.6
Nitta, K.7
-
38
-
-
33646401549
-
Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
-
Verma R, Kovari I, Soofi A, Nihalani D, Patrie K, Holzman LB. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 116: 1346-1359, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1346-1359
-
-
Verma, R.1
Kovari, I.2
Soofi, A.3
Nihalani, D.4
Patrie, K.5
Holzman, L.B.6
-
39
-
-
0032748298
-
Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity
-
Zenke FT, King CC, Bohl BP, Bokoch GM. Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. J Biol Chem 274: 32565-32573, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 32565-32573
-
-
Zenke, F.T.1
King, C.C.2
Bohl, B.P.3
Bokoch, G.M.4
-
40
-
-
34548040454
-
Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury
-
Zhang H, Cybulsky AV, Aoudjit L, Zhu J, Li H, Lamarche-Vane N, Takano T. Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury. Am J Physiol Renal Physiol 293: F148-F156, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Zhang, H.1
Cybulsky, A.V.2
Aoudjit, L.3
Zhu, J.4
Li, H.5
Lamarche-Vane, N.6
Takano, T.7
-
41
-
-
39349104907
-
Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes
-
Zhu J, Sun N, Aoudjit L, Li H, Kawachi H, Lemay S, Takano T. Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes. Kidney Int 73: 556-566, 2008
-
(2008)
Kidney Int
, vol.73
, pp. 556-566
-
-
Zhu, J.1
Sun, N.2
Aoudjit, L.3
Li, H.4
Kawachi, H.5
Lemay, S.6
Takano, T.7
|