2,3,7,8-Tetrachlorodibenzo-p-dioxin stimulates proliferation of HAPI microglia by affecting the Akt/GSK-3β/cyclin D1 signaling pathway

Toxicology Letters

Volumn 224, Issue 3, 2014, Pages 362-370

  Xu, Guangfei ^a,b   Li, Yuanye ^a   Yoshimoto, Katsuhiko ^b   Wu, Qiyun ^a   Chen, Gang ^a   Iwata, Takeo ^b   Mizusawa, Noriko ^b   Wan, Chunhua ^a   Nie, Xiaoke ^a  

^a NANTONG UNIVERSITY   (China)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin (TCDD); Akt; Cyclin D1; Glycogen synthase kinase 3 (GSK 3 ); Microglia; Proliferation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEASOME; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSCRIPTION; MICROGLIA; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84890204297     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.11.003     Document Type: Article

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