Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation

Biochemical Pharmacology

Volumn 81, Issue 2, 2011, Pages 304-313

  Pierre, Stéphane ^a,b   Bats, Anne Sophie ^a,b,c   Chevallier, Aline ^a,b   Bui, Linh Chi ^a,b   Ambolet Camoit, Ariane ^a,b   Garlatti, Michle ^a,b   Aggerbeck, Martine ^a,b   Barouki, Robert ^a,b,d   Coumoul, Xavier ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

AhR; Cell proliferation; Dioxin; Ras; SOS1

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ARTICLE; CELL PROLIFERATION; CELL STRAIN HEPG2; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; POLLUTANT; PRIORITY JOURNAL; PROMOTER REGION; SOS1 GENE;

CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEP G2 CELLS; HEPATOCYTES; HUMANS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RAS PROTEINS; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; RNA, SMALL INTERFERING; SOS1 PROTEIN; TETRACHLORODIBENZODIOXIN;

EID: 78650170612     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.10.003     Document Type: Article

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