Impaired innate mucosal immunity in aged mice permits prolonged streptococcus pneumoniae colonization

Infection and Immunity

Volumn 81, Issue 12, 2013, Pages 4615-4625

  Krone, Cassandra L ^a   Trzciński, Krzysztof ^a   Zborowski, Tomasz ^a   Sanders, Elisabeth A M ^a   Bogaert, Debby ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TOLL LIKE RECEPTOR 1;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COLONIZATION; CONTROLLED STUDY; IMMUNE DEFICIENCY; IMMUNOREGULATION; INFECTION SENSITIVITY; INNATE IMMUNITY; MACROPHAGE MIGRATION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; STREPTOCOCCUS PNEUMONIAE; UPPER RESPIRATORY TRACT;

AGE FACTORS; AGING; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL LOAD; CARRIER PROTEINS; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; FEMALE; IMMUNITY, INNATE; IMMUNITY, MUCOSAL; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; NASOPHARYNX; NF-KAPPA B; PNEUMOCOCCAL INFECTIONS; PPAR GAMMA; RESPIRATORY MUCOSA; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTOR 1;

EID: 84890165434     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00618-13     Document Type: Article

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