PPARγ mediates innate immunity by regulating the 1α,25-dihydroxyvitamin D3 induced hBD-3 and cathelicidin in human keratinocytes

Journal of Dermatological Science

Volumn 60, Issue 3, 2010, Pages 179-186

  Dai, Xiuju ^a   Sayama, Koji ^a   Tohyama, Mikiko ^a   Shirakata, Yuji ^a   Hanakawa, Yasushi ^a   Tokumaru, Sho ^a   Yang, Lujun ^a   Hirakawa, Satoshi ^a   Hashimoto, Koji ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

1 ,25 Dihydroxyvitamin D3; AP 1; Cathelicidin; HBD 3; Keratinocyte; PPAR

Indexed keywords

ADENOVIRUS VECTOR; BETA DEFENSIN 3; CALCITRIOL; CATHELICIDIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN C FOS; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FRA 1;

ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTRACELLULAR SIGNALING; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; VITAMIN D RESPONSIVE ELEMENT; WESTERN BLOTTING;

ANTIMICROBIAL CATIONIC PEPTIDES; BASE SEQUENCE; BETA-DEFENSINS; CALCITRIOL; CELLS, CULTURED; DNA PRIMERS; HUMANS; IMMUNITY, INNATE; KERATINOCYTES; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 78649496826     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.09.008     Document Type: Article

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