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Volumn 38, Issue 3, 2013, Pages 219-235

Can genotype be used to tailor treatment of obesity? State of the art and guidelines for future studies and applications

Author keywords

Gene environment interactions; Genotype; Obesity

Indexed keywords

BODY WEIGHT; CLINICAL PRACTICE; DIET; EXERCISE; GENE ACTIVITY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOME; GENOTYPE; HUMAN; METHODOLOGY; OBESITY; OBSERVATIONAL STUDY; PHENOTYPE; PRACTICE GUIDELINE; REVIEW;

EID: 84890156675     PISSN: 03911977     EISSN: 18271634     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (91)
  • 2
    • 84872336545 scopus 로고    scopus 로고
    • The genetics of obesity in transition
    • Demerath EW. The genetics of obesity in transition. Coll Antropol 2012;36:1161-8.
    • (2012) Coll Antropol , vol.36 , pp. 1161-1168
    • Demerath, E.W.1
  • 3
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • ENCODE Project Consortium, Dunham I, Kundaje A, Aldred SF, Collins PJ, Davis CA, Doyle F et al. An integrated encyclopedia of DNA elements in the human genome. Nature 2012;489:57-74.
    • (2012) Nature , vol.489 , pp. 57-74
    • Dunham, I.1    Kundaje, A.2    Aldred, S.F.3    Collins, P.J.4    Davis, C.A.5    Doyle, F.6
  • 4
    • 84875955036 scopus 로고    scopus 로고
    • Realizing the opportunities of genomics in health care
    • Ginsburg GS. Realizing the opportunities of genomics in health care. JAMA 2013;309:1463-4.
    • (2013) JAMA , vol.309 , pp. 1463-1464
    • Ginsburg, G.S.1
  • 6
    • 84859575363 scopus 로고    scopus 로고
    • Genetic determinants of common obesity and their value in prediction
    • Loos RJ. Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab 2012;26:211-26.
    • (2012) Best Pract Res Clin Endocrinol Metab , vol.26 , pp. 211-226
    • Loos, R.J.1
  • 7
    • 84863508910 scopus 로고    scopus 로고
    • Genetics of pediatric obesity
    • Manco M, Dallapiccola B. Genetics of pediatric obesity. Pediatrics 2012;130:123-33.
    • (2012) Pediatrics , vol.130 , pp. 123-133
    • Manco, M.1    Dallapiccola, B.2
  • 8
    • 80155182174 scopus 로고    scopus 로고
    • Developments in obesity genetics in the era of genome-wide association studies
    • Day FR, Loos RJ. Developments in obesity genetics in the era of genome-wide association studies. J Nutrigenet Nutrigenomics 2011;4:222-38.
    • (2011) J Nutrigenet Nutrigenomics , vol.4 , pp. 222-238
    • Day, F.R.1    Loos, R.J.2
  • 9
    • 84856243800 scopus 로고    scopus 로고
    • Genetic polymorphisms in adipokine genes and the risk of obesity: A systematic review and meta-analysis
    • Yu Z, Han S, Cao X, Zhu C, Wang X, Guo X. Genetic polymorphisms in adipokine genes and the risk of obesity: a systematic review and meta-analysis. Obesity (Silver Spring) 2012;20:396-406.
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 396-406
    • Yu, Z.1    Han, S.2    Cao, X.3    Zhu, C.4    Wang, X.5    Guo, X.6
  • 10
    • 84879410229 scopus 로고    scopus 로고
    • From obesity genetics to the future of personalized obesity therapy
    • In press
    • El-Sayed Moustafa JS, Froguel P. From obesity genetics to the future of personalized obesity therapy. Nat Rev Endocrinol 2013 [In press].
    • (2013) Nat Rev Endocrinol
    • El-Sayed Moustafa, J.S.1    Froguel, P.2
  • 11
    • 78650315390 scopus 로고    scopus 로고
    • Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine
    • Blakemore AI, Froguel P. Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine. Ann N Y Acad Sci 2010;1214:180-9.
    • (2010) Ann N Y Acad Sci , vol.1214 , pp. 180-189
    • Blakemore, A.I.1    Froguel, P.2
  • 13
    • 77649209853 scopus 로고    scopus 로고
    • Gene-environment interactions in obesity
    • Hetherington MM, Cecil JE. Gene-environment interactions in obesity. Forum Nutr 2010;63:195-203.
    • (2010) Forum Nutr , vol.63 , pp. 195-203
    • Hetherington, M.M.1    Cecil, J.E.2
  • 14
    • 69249208526 scopus 로고    scopus 로고
    • Gene-environment interactions and obesity - Further aspects of genomewide association studies
    • Andreasen CH, Andersen G. Gene-environment interactions and obesity - further aspects of genomewide association studies. Nutrition 2009;25:998-1003.
    • (2009) Nutrition , vol.25 , pp. 998-1003
    • Andreasen, C.H.1    Andersen, G.2
  • 15
    • 56849128391 scopus 로고    scopus 로고
    • Gene-environment interactions in the etiology of obesity: Defining the fundamentals
    • Silver Spring
    • Bouchard C. Gene-environment interactions in the etiology of obesity: defining the fundamentals. Obesity (Silver Spring) 2008;16(Suppl 3):S5-S10.
    • (2008) Obesity , vol.16 , Issue.SUPPL. 3
    • Bouchard, C.1
  • 16
    • 84876051003 scopus 로고    scopus 로고
    • Managing obesity in adults
    • Brown J. Managing obesity in adults. Nurs Times 2012;108:18-9.
    • (2012) Nurs Times , vol.108 , pp. 18-19
    • Brown, J.1
  • 17
    • 84872150076 scopus 로고    scopus 로고
    • Personalized medicine in women's obesity prevention and treatment: Implications for research, policy and practice
    • Yang N, Ginsburg GS, Simmons LA. Personalized medicine in women's obesity prevention and treatment: implications for research, policy and practice. Obes Rev 2013;14:145-61.
    • (2013) Obes Rev , vol.14 , pp. 145-161
    • Yang, N.1    Ginsburg, G.S.2    Simmons, L.A.3
  • 18
    • 84855549780 scopus 로고    scopus 로고
    • Paving the way for personalised behaviourally based prevention of obesity: Systematic search of the literature
    • Fister K, Vuletic S, Kern J. Paving the way for personalised behaviourally based prevention of obesity: systematic search of the literature. Coll Antropol 2012;36(Suppl 1):201-10.
    • (2012) Coll Antropol , vol.36 , Issue.SUPPL. 1 , pp. 201-210
    • Fister, K.1    Vuletic, S.2    Kern, J.3
  • 19
    • 70449465250 scopus 로고    scopus 로고
    • Genomic and personalized medicine: Foundations and applications
    • Ginsburg GS, Willard HF. Genomic and personalized medicine: foundations and applications. Transl Res 2009;154:277-87.
    • (2009) Transl Res , vol.154 , pp. 277-287
    • Ginsburg, G.S.1    Willard, H.F.2
  • 20
    • 84872021010 scopus 로고    scopus 로고
    • Genomic medicine: New frontiers and new challenges
    • Pasic MD, Samaan S, Yousef GM. Genomic medicine: new frontiers and new challenges. Clin Chem 2013,59:158-67.
    • (2013) Clin Chem , vol.59 , pp. 158-167
    • Pasic, M.D.1    Samaan, S.2    Yousef, G.M.3
  • 21
    • 84871727814 scopus 로고    scopus 로고
    • Clinical practice on the horizon: Personalized medicine
    • Chadwell K. Clinical practice on the horizon: personalized medicine. Clin Nurse Spec 2013;27:36-43.
    • (2013) Clin Nurse Spec , vol.27 , pp. 36-43
    • Chadwell, K.1
  • 22
    • 84870560360 scopus 로고    scopus 로고
    • Role of genomics on the path to personalized medicine
    • Tremblay J, Hamet P. Role of genomics on the path to personalized medicine. Metabolism 2013;62(Suppl 1):S2-5.
    • (2013) Metabolism , vol.62 , Issue.SUPPL. 1
    • Tremblay, J.1    Hamet, P.2
  • 23
    • 77955594299 scopus 로고    scopus 로고
    • Physiological insights gained from gene expression analysis in obesity and diabetes
    • Keller MP, Attie AD. Physiological insights gained from gene expression analysis in obesity and diabetes. Annu Rev Nutr 2010;30:341-64.
    • (2010) Annu Rev Nutr , vol.30 , pp. 341-364
    • Keller, M.P.1    Attie, A.D.2
  • 24
    • 84865447919 scopus 로고    scopus 로고
    • The epigenetic lorax: Gene-environment interactions in human health
    • Latham KE, Sapienza C, Engel N. The epigenetic lorax: gene-environment interactions in human health. Epigenomics 2012;4:383-402.
    • (2012) Epigenomics , vol.4 , pp. 383-402
    • Latham, K.E.1    Sapienza, C.2    Engel, N.3
  • 25
    • 84857437426 scopus 로고    scopus 로고
    • Minireview: Epigenetics of obesity and diabetes in humans
    • Slomko H, Heo HJ, Einstein FH. Minireview: Epigenetics of obesity and diabetes in humans. Endocrinology 2012;153:1025-30.
    • (2012) Endocrinology , vol.153 , pp. 1025-1030
    • Slomko, H.1    Heo, H.J.2    Einstein, F.H.3
  • 26
    • 84862287116 scopus 로고    scopus 로고
    • Investigating potential mechanisms of obesity by metabolomics
    • Xie B, Waters MJ, Schirra HJ. Investigating potential mechanisms of obesity by metabolomics. J Biomed Biotechnol 2012;2012:805683.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 805683
    • Xie, B.1    Waters, M.J.2    Schirra, H.J.3
  • 27
    • 80051905337 scopus 로고    scopus 로고
    • Problems in identifying predictors and correlates of weight loss and maintenance: Implications for weight control therapies based on behaviour change
    • Stubbs J, Whybrow S, Teixeira P, Blundell J, Lawton C, Westenhoefer J et al. Problems in identifying predictors and correlates of weight loss and maintenance: implications for weight control therapies based on behaviour change. Obes Rev 2011;12:688-708.
    • (2011) Obes Rev , vol.12 , pp. 688-708
    • Stubbs, J.1    Whybrow, S.2    Teixeira, P.3    Blundell, J.4    Lawton, C.5    Westenhoefer, J.6
  • 28
    • 0032200779 scopus 로고    scopus 로고
    • Gender differences in changes in subcutaneous and intra-abdominal fat during weight reduction: An ultrasound study
    • Wirth A, Steinmetz B. Gender differences in changes in subcutaneous and intra-abdominal fat during weight reduction: an ultrasound study. Obes Res 1998;6:393-9. (Pubitemid 128679688)
    • (1998) Obesity Research , vol.6 , Issue.6 , pp. 393-399
    • Wirth, A.1    Steinmetz, B.2
  • 29
    • 84857817158 scopus 로고    scopus 로고
    • What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A Systematic review
    • Ara R, Blake L, Gray L, Hernandez M, Crowther M, Dunkley A et al. What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A Systematic review. Health Technol Assess 2012;16:1-195.
    • (2012) Health Technol Assess , vol.16 , pp. 1-195
    • Ara, R.1    Blake, L.2    Gray, L.3    Hernandez, M.4    Crowther, M.5    Dunkley, A.6
  • 31
    • 61349179515 scopus 로고    scopus 로고
    • Sex differences in obesity and the regulation of energy homeostasis
    • Stock Conference 2008 Working Group
    • Lovejoy JC, Sainsbury A; Stock Conference 2008 Working Group. Sex differences in obesity and the regulation of energy homeostasis. Obes Rev2009;10:154-67.
    • (2009) Obes Rev , vol.10 , pp. 154-167
    • Lovejoy, J.C.1    Sainsbury, A.2
  • 32
    • 84890147638 scopus 로고    scopus 로고
    • Women's higher health risks in the obesogenic environment: A gender nutrition approach to metabolic dimorphism with predictive, preventive, and personalised medicine
    • Shapira N. Women's higher health risks in the obesogenic environment: a gender nutrition approach to metabolic dimorphism with predictive, preventive, and personalised medicine. EPMA J 2013;4:1.
    • (2013) EPMA J , vol.4 , pp. 1
    • Shapira, N.1
  • 34
    • 84875512210 scopus 로고    scopus 로고
    • A longitudinal analysis of adolescent smoking: Using smoking status to differentiate the influence of body weight measures
    • Hong T, Johnson C. A longitudinal analysis of adolescent smoking: using smoking status to differentiate the influence of body weight measures. J Sch Health 2013;83:314-21.
    • (2013) J Sch Health , vol.83 , pp. 314-321
    • Hong, T.1    Johnson, C.2
  • 35
    • 84869457261 scopus 로고    scopus 로고
    • The expanding scope of DNA sequencing
    • Shendure J, Lieberman Aiden E. The expanding scope of DNA sequencing. Nat Biotechnol 2012;30:1084-94.
    • (2012) Nat Biotechnol , vol.30 , pp. 1084-1094
    • Shendure, J.1    Lieberman Aiden, E.2
  • 36
    • 79952468590 scopus 로고    scopus 로고
    • Genome-sequencing anniversary. Human genome sequencing: Celebrating 10 years
    • Al-Gazali L. Genome-sequencing anniversary. Human genome sequencing: celebrating 10 years. Science 2011;331:873.
    • (2011) Science , vol.331 , pp. 873
    • Al-Gazali, L.1
  • 37
    • 84879627975 scopus 로고    scopus 로고
    • Next-generation sequencing platforms
    • Palo Alto Calif In press
    • Mardis ER. Next-generation sequencing platforms. Annu Rev Anal Chem (Palo Alto Calif) 2013 [In press].
    • (2013) Annu Rev Anal Chem
    • Mardis, E.R.1
  • 38
    • 84880943505 scopus 로고    scopus 로고
    • Beyond sequencing: Optical mapping of DNA in the age of nanotechnology and nanoscopy
    • In press
    • Levy-Sakin M, Ebenstein Y. Beyond sequencing: optical mapping of DNA in the age of nanotechnology and nanoscopy. Curr Opin Biotechnol 2013 [In press].
    • (2013) Curr Opin Biotechnol
    • Levy-Sakin, M.1    Ebenstein, Y.2
  • 39
    • 84876917161 scopus 로고    scopus 로고
    • Chapter 15: Disease gene prioritization
    • Bromberg Y. Chapter 15: disease gene prioritization. PLoS Comput Biol 2013;9:e1002902.
    • (2013) PLoS Comput Biol , vol.9
    • Bromberg, Y.1
  • 40
    • 84878569025 scopus 로고    scopus 로고
    • Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity
    • Wheeler E, Huang N, Bochukova EG, Keogh JM, Lindsay S, Garg S et al. Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. Nat Genet 2013;45:513-7.
    • (2013) Nat Genet , vol.45 , pp. 513-517
    • Wheeler, E.1    Huang, N.2    Bochukova, E.G.3    Keogh, J.M.4    Lindsay, S.5    Garg, S.6
  • 41
    • 78751700313 scopus 로고    scopus 로고
    • Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis
    • Jarick I, Vogel CI, Scherag S, Schafer H, Hebebrand J, Hinney A et al. Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis. Hum Mol Genet 2011;20:840-52.
    • (2011) Hum Mol Genet , vol.20 , pp. 840-852
    • Jarick, I.1    Vogel, C.I.2    Scherag, S.3    Schafer, H.4    Hebebrand, J.5    Hinney, A.6
  • 42
    • 84872087895 scopus 로고    scopus 로고
    • Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study
    • Yang TL, Guo Y, Shen H, Li J, Glessner JT, Qiu C et al. Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study. J Clin Endocrinol Metab 2013;98:E191-5.
    • (2013) J Clin Endocrinol Metab , vol.98
    • Yang, T.L.1    Guo, Y.2    Shen, H.3    Li, J.4    Glessner, J.T.5    Qiu, C.6
  • 43
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio TA. Genomewide association studies and assessment of the risk of disease. N Engl J Med 2010;363:166-76.
    • (2010) N Engl J Med , vol.363 , pp. 166-176
    • Manolio, T.A.1
  • 44
    • 35748970488 scopus 로고    scopus 로고
    • Genome-wide association to body mass index and waist circumference: The Framingham Heart Study 100K project
    • Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. BMC Med Genet 2007;8(Suppl 1):S18.
    • (2007) BMC Med Genet , vol.8 , Issue.SUPPL. 1
    • Fox, C.S.1    Heard-Costa, N.2    Cupples, L.A.3    Dupuis, J.4    Vasan, R.S.5    Atwood, L.D.6
  • 47
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Wilier CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34.
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Wilier, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5    Heid, I.M.6
  • 50
    • 84888329209 scopus 로고    scopus 로고
    • Genome-wide association studies of obesity and metabolic syndrome
    • Fall T, Ingelsson E. Genome-wide association studies of obesity and metabolic syndrome. Mol Cell Endocrinol 2012,S0303-7207.
    • (2012) Mol Cell Endocrinol
    • Fall, T.1    Ingelsson, E.2
  • 51
    • 84878594902 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
    • Berndt SI, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa MF et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013;45:501-12.
    • (2013) Nat Genet , vol.45 , pp. 501-512
    • Berndt, S.I.1    Gustafsson, S.2    Magi, R.3    Ganna, A.4    Wheeler, E.5    Feitosa, M.F.6
  • 52
    • 84860523798 scopus 로고    scopus 로고
    • From genotype x environment interaction to gene x environment interaction
    • Crossa J. From genotype x environment interaction to gene x environment interaction. Curr Genomics 2012;13:225-44.
    • (2012) Curr Genomics , vol.13 , pp. 225-244
    • Crossa, J.1
  • 56
    • 84879689001 scopus 로고    scopus 로고
    • Do we know enough? A scientific and ethical analysis of the basis for genetic-based personalized nutrition
    • In press
    • Gorman U, Mathers JC, Grimaldi KA, Ahlgren J, Nordstrom K. Do we know enough? A scientific and ethical analysis of the basis for genetic-based personalized nutrition. Genes Nutr 2013 [In press].
    • (2013) Genes Nutr
    • Gorman, U.1    Mathers, J.C.2    Grimaldi, K.A.3    Ahlgren, J.4    Nordstrom, K.5
  • 57
    • 84872853014 scopus 로고    scopus 로고
    • Nutrigenetics and metabolic disease: Current status and implications for personalised nutrition
    • Phillips CM. Nutrigenetics and metabolic disease: current status and implications for personalised nutrition. Nutrients 2013;5:32-57.
    • (2013) Nutrients , vol.5 , pp. 32-57
    • Phillips, C.M.1
  • 58
    • 33846650121 scopus 로고    scopus 로고
    • APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study
    • DOI 10.1007/s00109-006-0147-0
    • Corella D, Lai CQ, Demissie S, Cupples LA, Manning AK, Tucker KL et al. APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. J Mol Med (Berl) 2007;85:119-28. (Pubitemid 46183611)
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.2 , pp. 119-128
    • Corella, D.1    Lai, C.-Q.2    Demissie, S.3    Cupples, L.A.4    Manning, A.K.5    Tucker, K.L.6    Ordovas, J.M.7
  • 59
    • 84862907763 scopus 로고    scopus 로고
    • A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI
    • Corella D, Arnett DK, Tucker KL, Kabagambe EK, Tsai M, Parnell LD et al. A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr. 2011;141:2219-25.
    • (2011) J Nutr , vol.141 , pp. 2219-2225
    • Corella, D.1    Arnett, D.K.2    Tucker, K.L.3    Kabagambe, E.K.4    Tsai, M.5    Parnell, L.D.6
  • 60
    • 54749093633 scopus 로고    scopus 로고
    • Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin
    • Smith CE, Tucker KL, Yiannakouris N, Garcia-Bailo B, Mattei J, Lai CQ et al. Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin. J Nutr 2008;138:1852-8.
    • (2008) J Nutr , vol.138 , pp. 1852-1858
    • Smith, C.E.1    Tucker, K.L.2    Yiannakouris, N.3    Garcia-Bailo, B.4    Mattei, J.5    Lai, C.Q.6
  • 61
    • 79955531774 scopus 로고    scopus 로고
    • The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site
    • Richardson K, Louie-Gao Q, Arnett DK, Parnell LD, Lai CQ, Davalos A et al. The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS One 2011;6:e17944.
    • (2011) PLoS One , vol.6
    • Richardson, K.1    Louie-Gao, Q.2    Arnett, D.K.3    Parnell, L.D.4    Lai, C.Q.5    Davalos, A.6
  • 63
    • 78649754353 scopus 로고    scopus 로고
    • ADAM17-i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study
    • Junyent M, Parnell LD, Lai CQ, Arnett DK, Tsai MY, Kabagambe EK et al. ADAM17-i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study. Nutr Metab Cardiovasc Dis 2010;20:698-705.
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 698-705
    • Junyent, M.1    Parnell, L.D.2    Lai, C.Q.3    Arnett, D.K.4    Tsai, M.Y.5    Kabagambe, E.K.6
  • 64
    • 70350686380 scopus 로고    scopus 로고
    • Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity
    • Sonestedt E, Roos C, Gullberg B, Ericson U, Wirfält E, Orho-Melander M. Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity. Am J Clin Nutr 2009;90:1418-25.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1418-1425
    • Sonestedt, E.1    Roos, C.2    Gullberg, B.3    Ericson, U.4    Wirfält, E.5    Orho-Melander, M.6
  • 66
    • 0345306138 scopus 로고    scopus 로고
    • Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass
    • DOI 10.1093/hmg/ddg318
    • Memisoglu A, Hu FB, Hankinson SE, Manson JE, De Vivo I, Willett WC et al. Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass. Hum Mol Genet 2003;12:2923-9. (Pubitemid 37442020)
    • (2003) Human Molecular Genetics , vol.12 , Issue.22 , pp. 2923-2929
    • Memisoglu, A.1    Hu, F.B.2    Hankinson, S.E.3    Manson, J.E.4    De Vivo, I.5    Willett, W.C.6    Hunter, D.J.7
  • 67
    • 84857051628 scopus 로고    scopus 로고
    • Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. Prospective study
    • Lond
    • Lamri A, Abi Khalil C, Jaziri R, Velho G, Lantieri O, Vol S et al. Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study. Int J Obes (Lond) 2012;36:218-24.
    • (2012) Int J Obes , vol.36 , pp. 218-224
    • Lamri, A.1    Abi Khalil, C.2    Jaziri, R.3    Velho, G.4    Lantieri, O.5    Vol, S.6
  • 68
    • 84862069805 scopus 로고    scopus 로고
    • High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults
    • Phillips CM, Kesse-Guyot E, McManus R, Hercberg S, Lairon D, Planells R et al. High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults. J Nutr 2012;142:824-31.
    • (2012) J Nutr , vol.142 , pp. 824-831
    • Phillips, C.M.1    Kesse-Guyot, E.2    McManus, R.3    Hercberg, S.4    Lairon, D.5    Planells, R.6
  • 70
    • 28344454483 scopus 로고    scopus 로고
    • Increased risk of obesity resulting from the interaction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men
    • DOI 10.2188/jea.15.203
    • Miyaki K, Sutani S, Kikuchi H, Takei I, Murata M, Watanabe K et al. Increased risk of obesity resulting from the interaction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men. J Epidemiol 2005;15:203-10. (Pubitemid 41715785)
    • (2005) Journal of Epidemiology , vol.15 , Issue.6 , pp. 203-210
    • Miyaki, K.1    Sutani, S.2    Kikuchi, H.3    Takei, I.4    Murata, M.5    Watanabe, K.6    Omae, K.7
  • 71
    • 84876176442 scopus 로고    scopus 로고
    • Challenges in reproducibility of genetic association studies: Lessons learned from the obesity field
    • Lond
    • Li A, Meyre D. Challenges in reproducibility of genetic association studies: lessons learned from the obesity field. Int J Obes (Lond) 2013;37-67.
    • (2013) Int J Obes , pp. 37-67
    • Li, A.1    Meyre, D.2
  • 72
    • 70449650464 scopus 로고    scopus 로고
    • APOA2, dietary fat, and body mass index: Replication of a gene-diet interaction in 3 independent populations
    • Corella D, Peloso G, Arnett DK, Demissie S, Cupples LA, Tucker K et al. APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med 2009;169:1897-906.
    • (2009) Arch Intern Med , vol.169 , pp. 1897-1906
    • Corella, D.1    Peloso, G.2    Arnett, D.K.3    Demissie, S.4    Cupples, L.A.5    Tucker, K.6
  • 73
    • 79955840457 scopus 로고    scopus 로고
    • Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asian populations: Replication of a gene-saturated fat interaction
    • Lond
    • Corella D, Tai ES, Sorli JV, Chew SK, Coltell O, Sotos-Prieto M et al. Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asian populations: replication of a gene-saturated fat interaction. Int J Obes (Lond) 2011;35:666-75.
    • (2011) Int J Obes , vol.35 , pp. 666-675
    • Corella, D.1    Tai, E.S.2    Sorli, J.V.3    Chew, S.K.4    Coltell, O.5    Sotos-Prieto, M.6
  • 76
    • 77449098763 scopus 로고    scopus 로고
    • Nutrigenomics in cardiovascular medicine
    • Corella D, Ordovas JM. Nutrigenomics in cardiovascular medicine. Circ Cardiovasc Genet 2009;2:637-51.
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 637-651
    • Corella, D.1    Ordovas, J.M.2
  • 77
    • 84871356839 scopus 로고    scopus 로고
    • Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: New effects on alcohol consumption
    • Corella D, Ortega-Azorín C, Sorlí JV, Covas MI, Carrasco P, Salas-Salvado J et al. Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption. PLoS One 2012;7:e52344.
    • (2012) PLoS One , vol.7
    • Corella, D.1    Ortega-Azorín, C.2    Sorlí, J.V.3    Covas, M.I.4    Carrasco, P.5    Salas-Salvado, J.6
  • 78
    • 82455175773 scopus 로고    scopus 로고
    • Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children
    • Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E et al. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med 2011;8:e1001116.
    • (2011) PLoS Med , vol.8
    • Kilpeläinen, T.O.1    Qi, L.2    Brage, S.3    Sharp, S.J.4    Sonestedt, E.5    Demerath, E.6
  • 79
    • 77249107010 scopus 로고    scopus 로고
    • FTO genotype and the weight loss benefits of moderate intensity exercise
    • Silver Spring
    • Mitchell JA, Church TS, Rankinen T, Earnest CP, Sui X, Blair SN. FTO genotype and the weight loss benefits of moderate intensity exercise. Obesity (Silver Spring) 2010;18:641-3.
    • (2010) Obesity , vol.18 , pp. 641-643
    • Mitchell, J.A.1    Church, T.S.2    Rankinen, T.3    Earnest, C.P.4    Sui, X.5    Blair, S.N.6
  • 81
    • 70450273183 scopus 로고    scopus 로고
    • Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans
    • Lond
    • Grau K, Hansen T, Holst C, Astrup A, Saris WH, Arner P et al. Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans. Int J Obes (Lond) 2009;33:1227-34.
    • (2009) Int J Obes , vol.33 , pp. 1227-1234
    • Grau, K.1    Hansen, T.2    Holst, C.3    Astrup, A.4    Saris, W.H.5    Arner, P.6
  • 82
    • 84868029849 scopus 로고    scopus 로고
    • FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: The POUNDS LOST Trial
    • Zhang X, Qi Q, Zhang C, Smith SR, Hu FB, Sacks FM et al. FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial. Diabetes 2012;61:3005-11.
    • (2012) Diabetes , vol.61 , pp. 3005-3011
    • Zhang, X.1    Qi, Q.2    Zhang, C.3    Smith, S.R.4    Hu, F.B.5    Sacks, F.M.6
  • 83
    • 84867812195 scopus 로고    scopus 로고
    • TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weightloss intervention
    • Mattei J, Qi Q, Hu FB, Sacks FM, Qi L. TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weightloss intervention. Am J Clin Nutr 2012;96:1129-36.
    • (2012) Am J Clin Nutr , vol.96 , pp. 1129-1136
    • Mattei, J.1    Qi, Q.2    Hu, F.B.3    Sacks, F.M.4    Qi, L.5
  • 84
    • 84859073619 scopus 로고    scopus 로고
    • Dietary fiber intake modulates the association between variants in TCF7L2 and weight loss during a lifestyle intervention
    • Heni M, Herzberg-Schafer S, Machicao F, Haring HU, Fritsche A. Dietary fiber intake modulates the association between variants in TCF7L2 and weight loss during a lifestyle intervention. Diabetes Care 2012;35:e24.
    • (2012) Diabetes Care , vol.35
    • Heni, M.1    Herzberg-Schafer, S.2    Machicao, F.3    Haring, H.U.4    Fritsche, A.5
  • 85
    • 77950344135 scopus 로고    scopus 로고
    • Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes
    • Haupt A, Thamer C, Heni M, Ketterer C, Machann J, Schick F et al. Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes. Diabetes 2010;59:747-50.
    • (2010) Diabetes , vol.59 , pp. 747-750
    • Haupt, A.1    Thamer, C.2    Heni, M.3    Ketterer, C.4    Machann, J.5    Schick, F.6
  • 86
    • 84884907373 scopus 로고    scopus 로고
    • Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program
    • Silver Spring In press
    • Pan Q, Delahanty LM, Jablonski KA, Knowler WC, Kahn SE, Florez JC et al. Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program. Obesity (Silver Spring) 2013 [In press).
    • (2013) Obesity
    • Pan, Q.1    Delahanty, L.M.2    Jablonski, K.A.3    Knowler, W.C.4    Kahn, S.E.5    Florez, J.C.6
  • 87
    • 84873721053 scopus 로고    scopus 로고
    • FTO and MC4R gene variants determine BMI changes in children after intensive lifestyle intervention
    • Zlatohlavek L, Vrablik M, Motykova E, Ceska R, Vasickova L, Dlouha D et al. FTO and MC4R gene variants determine BMI changes in children after intensive lifestyle intervention. Clin Biochem 2013;46:313-6.
    • (2013) Clin Biochem , vol.46 , pp. 313-316
    • Zlatohlavek, L.1    Vrablik, M.2    Motykova, E.3    Ceska, R.4    Vasickova, L.5    Dlouha, D.6
  • 89
    • 84869816034 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery
    • Valette M, Poitou C, Le Beyec J, Bouillot JL, Clement K, Czernichow S. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PLoS One 2012;7:e48221.
    • (2012) PLoS One , vol.7
    • Valette, M.1    Poitou, C.2    Le Beyec, J.3    Bouillot, J.L.4    Clement, K.5    Czernichow, S.6
  • 90
  • 91
    • 84860267712 scopus 로고    scopus 로고
    • Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: The DIOGENES study
    • Larsen LH, Angquist L, Vimaleswaran KS, Hager J, Viguerie N, Loos RJ et al. Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study. Am J Clin Nutr 2012;95:1254-60.
    • (2012) Am J Clin Nutr , vol.95 , pp. 1254-1260
    • Larsen, L.H.1    Angquist, L.2    Vimaleswaran, K.S.3    Hager, J.4    Viguerie, N.5    Loos, R.J.6


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