MiRNomes of haematopoietic stem cells and dendritic cells identify miR-30b as a regulator of Notch1

Nature Communications

Volumn 4, Issue , 2013, Pages

  Su, Xiaoping ^a   Qian, Cheng ^a   Zhang, Qian ^b   Hou, Jin ^a   Gu, Yan ^a   Han, Yanmei ^a   Chen, Yongjian ^a   Jiang, Minghong ^b   Cao, Xuetao ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; MICRORNA; MICRORNA 30B; NITRIC OXIDE; NOTCH1 RECEPTOR; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

BIOLOGICAL DEVELOPMENT; BONE; GENETIC ANALYSIS; IMMUNE RESPONSE; MATURATION; RNA;

ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; DENDRITIC CELL; EPIGENETIC REPRESSION; HEMATOPOIETIC STEM CELL; HISTONE MODIFICATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; UPREGULATION;

ANIMALS; CELLS, CULTURED; DENDRITIC CELLS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HISTONES; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; MICRORNAS; NITRIC OXIDE; RECEPTOR, NOTCH1; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84890156326     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3903     Document Type: Article

References (49)

1. Belz, G. T. & Nutt, S. L. Transcriptional programming of the dendritic cell network. Nat. Rev. Immunol. 12, 101-113 (2012).
2. King, K. Y. & Goodell, M. A. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat. Rev. Immunol. 11, 685-692 (2011).
3. Auffray, C., Sieweke, M. H. & Geissmann, F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu. Rev. Immunol. 27, 669-692 (2009).
4. Qian, C. & Cao, X. Naturally occurring CD1c human regulatory dendritic cells: Immunoregulators that are expanded in response to E. coli infection. Eur. J. Immunol. 42, 1388-1392 (2012).
5. Satpathy, A. T., Wu, X., Albring, J. C. & Murphy, K. M. Re (de) fining the dendritic cell lineage. Nat. Immunol. 13, 1145-1154 (2012).
6. Ebert, M. S. & Sharp, P. A. Roles for microRNAs in conferring robustness to biological processes. Cell 149, 515-524 (2012).
7. Lodish, H. F., Zhou, B., Liu, G. & Chen, C.-Z. Micromanagement of the immune system by microRNAs. Nat. Rev. Immunol. 8, 120-130 (2008). (Pubitemid 351161305)
8. Fontana, L. et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat. Cell Biol. 9, 775-787 (2007). (Pubitemid 47019464)
9. Rodriguez, A. et al. Requirement of bic/microRNA-155 for normal immune function. Science 316, 608-611 (2007). (Pubitemid 46683148)
10. Wang, P. et al. Identification of resting and type I IFN-activated human NK cell miRNomes reveals microRNA-378 and microRNA-30e as negative regulators of NK cell cytotoxicity. J. Immunol. 189, 211-221 (2012).
11. Steiner, D. F. et al. MicroRNA-29 regulates T-box transcription factors and interferon-gamma production in helper T cells. Immunity 35, 169-181 (2011).
12. Thai, T.-H. et al. Regulation of the germinal center response by microRNA-155. Science 316, 604-608 (2007). (Pubitemid 46683147)
13. Bai, Y. et al. Integrin CD11b Negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a. J. Immunol. 188, 5293-5302 (2012).
14. Shortman, K. & Liu, Y.-J. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2, 151-161 (2002). (Pubitemid 37336516)
15. Zhang, M. et al. Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat. Immunol. 5, 1124-1133 (2004). (Pubitemid 39549626)
16. Turner, M. L., Schnorfeil, F. M. & Brocker, T. MicroRNAs regulate dendritic cell differentiation and function. J. Immunol. 187, 3911-3917 (2011).
17. Li, H. S., Greeley, N., Sugimoto, N., Liu, Y. J. & Watowich, S. S. miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. PLoS One 7, e52341 (2012).
18. Min, S. et al. TGF-b-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38 MAPK, MAP2K4 and MAP2K7. Genes Immun. 13, 621-631 (2012).
19. Dunand-Sauthier, I. et al. Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function. Blood 117, 4490-4500 (2011).
20. Kuchen, S. et al. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity 32, 828-839 (2010).
21. Kim, V. N., Han, J. & Siomi, M. C. Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell Biol. 10, 126-139 (2009).
22. Popovic, R. et al. Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization. Blood 113, 3314-3322 (2009).
23. Jin, P. et al. Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis. J. Transl. Med. 6, 39 (2008).
24. Houbaviy, H. B., Murray, M. F. & Sharp, P. A. Embryonic stem cell-specific microRNAs. Dev. Cell 5, 351-358 (2003). (Pubitemid 37006477)
25. Chien, C.-H. et al. Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data. Nucleic Acids Res. 39, 9345-9356 (2011).
26. Beresford, G. W. & Boss, J. M. CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter. Nat. Immunol. 2, 652-657 (2001). (Pubitemid 32677634)
27. Chen, X. et al. Identification and characterization of novel amphioxus microRNAs by Illumina sequencing. Genome Biol. 10, R78 (2009).
28. Datta, J. et al. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res. 68, 5049-5058 (2008).
29. Zhao, X., Nicholls, J. M. & Chen, Y.-G. Severe acute respiratory syndromeassociated Coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signaling. J. Biol. Chem. 283, 3272-3280 (2008).
30. Ihn, H., Yamane, K., Asano, Y., Jinnin, M. & Tamaki, K. Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts. Rheumatology 45, 157-165 (2006). (Pubitemid 43160075)
31. Loots, G. G. & Ovcharenko, I. rVISTA 2.0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res. 32, 217-221 (2004).
32. Qian, L. et al. Regulatory dendritic cells program B cells to differentiate into CD19hiFcgammaIIbhi regulatory B cells through IFN-beta and CD40L. Blood 120, 581-591 (2012).
33. Neilson, J. R., Zheng, G. X. Y., Burge, C. B. & Sharp, P. A. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev. 21, 578-589 (2007). (Pubitemid 46409472)
34. Ma, F. et al. MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J. Immunol. 184, 6053-6059 (2010).
35. Ma, F. et al. The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nat. Immunol. 12, 861-869 (2011).
36. Hou, J. et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 19, 232-243 (2011).
37. Landgraf, P. et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129, 1401-1414 (2007). (Pubitemid 46970709)
38. Bar, M. et al. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells 26, 2496-2505 (2008).
39. Basso, K. et al. Identification of the human mature B cell miRNome. Immunity 30, 744-752 (2009).
40. Morgan, H. D., Santos, F., Green, K., Dean, W. & Reik, W. Epigenetic reprogramming in mammals. Hum. Mol. Genet. 14, R47-R58 (2005). (Pubitemid 40542620)
41. Lund, A. H. & Van Lohuizen, M. Epigenetics and cancer. Genes Dev. 18, 2315-2335 (2004). (Pubitemid 39310518)
42. Hackanson, B. et al. Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia. Cancer Res. 68, 3142-3151 (2008).
43. Lujambio, A. et al. A microRNA DNA methylation signature for human cancer metastasis. Proc. Natl. Acad. Sci. USA 105, 13556-13561 (2008).
44. Toyota, M. et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 68, 4123-4132 (2008).
45. Xu, H. et al. Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nat. Immunol. 13, 642-650 (2012).
46. Palaga, T. et al. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur. J. Immunol. 38, 174-183 (2007).
47. Zhang, Q. et al. Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signalregulated kinase 1/2-mediated nuclear factor kappaB activation. J. Biol. Chem. 287, 6208-6217 (2012).
48. Qian, C. et al. TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation. Blood 108, 2307-2315 (2006). (Pubitemid 44497514)
49. Benson, R. A. et al. Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production. Eur. J. Immunol. 35, 859-869 (2005). (Pubitemid 40425542)