A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 2, 2008, Pages 623-628

  Kieback, Elisa ^a   Charo, Jehad ^a   Sommermeyer, Daniel ^a   Blankenstein, Thomas ^a,b   Uckert, Wolfgang ^a,c  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Adoptive T cell therapy; Antibody depletion; myc tag; Suicide; TCR

Indexed keywords

MYC PROTEIN; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANTIGEN BINDING; ARTICLE; CELL TRANSFER; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; CELL SEPARATION; COMPLEMENT SYSTEM PROTEINS; DIABETES COMPLICATIONS; FEMALE; HUMANS; IMMUNOTHERAPY, ADOPTIVE; JURKAT CELLS; MALE; MICE; MICE, INBRED C57BL; MODELS, GENETIC; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ANTIGEN, T-CELL; RETROVIRIDAE; T-LYMPHOCYTES;

MURINAE; MUS;

EID: 38649127824     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710198105     Document Type: Article

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