Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer

Nature Medicine

Volumn 8, Issue 6, 2002, Pages 631-637

  Knabel, Michael ^a   Franz, Tobias J ^a   Schiemann, Matthias ^a   Wulf, Anna ^a   Villmow, Brigitte ^a   Schmidt, Burkhard ^b   Bernhard, Helga ^b   Wagner, Hermann ^a   Busch, Dirk H ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LISTERIA; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; TEMPERATURE;

ADOPTIVE TRANSFER; ANIMALS; CELL SEPARATION; HISTOCOMPATIBILITY ANTIGENS; IMMUNOHISTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED BALB C; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

ANIMALIA; LISTERIA;

EID: 0036284986     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0602-631     Document Type: Article

References (25)

1. + T cells using an ELISPOT assay
2. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
3. Analysis and sorting of live cells to secreted molecules, relocated to a cell-surface affinity matrix
4. Phenotypic analysis of antigen specific T lymphocytes
5. A new look at T cells
6. Coordinate regulation of complex T cell populations responding to bacterial infection
7. Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness
8. T cell affinity maturation by selective expansion during infection
9. Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection
10. MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen
11. A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex
12. Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent
13. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
14. Antigen-specific modulation of an immune response by in vivo administration of soluble MHC class I tetramers
15. Antigen-specific blockade of T cells in vivo using dimeric MHC peptide
16. Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts
17. Reconsitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
18. Infusion of cytotoxic T cells for prevention and treatment of Epstein-Barr Virus-induced lymphoma in allogeneic transplant recipients
19. Processing of Listeria monocytogenes antigens and the in vivo T-cell response to bacterial infection
20. MHC class I/peptide stability: Implications for immunodominance, in vitro proliferation and diversity of responding CTL
21. CD8 T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo
22. Mutagenesis of a flexible loop in streptavidin leads to higher affinity for the Strep-tag II peptide and improved performance in recombinant protein purification
23. Increased TCR avidity after T cell activation: A mechanism for sensing low-density antigen
24. +T cells usable in immunotherapy
25. Cutting edge: Rapid cloning of tumor-specific CTL suitable for adoptive immunotherapy of melanoma