Antiarrhythmic properties of some 1,4-disubstituted piperazine derivatives with α1-adrenoceptor affinities

European Journal of Pharmacology

Volumn 720, Issue 1-3, 2013, Pages 237-246

  Kubacka, Monika ^a   Mogilski, Szczepan ^a   Filipek, Barbara ^a   Marona, Henryk ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

1 adrenoceptor; Antiarrhythmic activity; Ischemia; Piperazine derivative

Indexed keywords

ADRENALIN; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BARIUM CHLORIDE; BETA 1 ADRENERGIC RECEPTOR; GLYCERYL TRINITRATE; MH 101; MH 76; MH 77; MH 78; MH 79; MH 88; NITRATE; NITRIC OXIDE; NITRITE; PIPERAZINE DERIVATIVE; POTASSIUM CHANNEL; PROPRANOLOL; QUINIDINE; SODIUM CHANNEL; UNCLASSIFIED DRUG; URAPIDIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; BRAIN HOMOGENATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CORONARY ARTERY OCCLUSION; CORONARY REPERFUSION; DISEASE ASSOCIATION; DRUG MEGADOSE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TISSUE LEVEL; ELECTROCARDIOGRAPHY; EXTRASYSTOLE; HEART ARRHYTHMIA; HEART BEAT; HEART MUSCLE ISCHEMIA; HEART RATE; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; IN VITRO STUDY; IN VIVO STUDY; INCIDENCE; LIPID PEROXIDATION; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; QRS COMPLEX; QT INTERVAL; RAT; REPERFUSION INJURY; RISK REDUCTION;

ANTIARRHYTHMIC ACTIVITY; ISCHEMIA; PIPERAZINE DERIVATIVE; Α(1)-ADRENOCEPTOR;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CEREBRAL CORTEX; EPINEPHRINE; HEART; MALE; NITRATES; NITRITES; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1;

EID: 84890126369     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.10.021     Document Type: Article

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