Repeated exposure of mouse dermal fibroblasts at a sub-cytotoxic dose of UVB leads to premature senescence: A robust model of cellular photoaging

Journal of Dermatological Science

Volumn 73, Issue 1, 2014, Pages 49-56

  Zeng, Ji ping ^a   Bi, Bo ^a   Chen, Liang ^a   Yang, Ping ^a   Guo, Yu ^a   Zhou, Yi qun ^a   Liu, Tian yi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Dermal fibroblast; Photoaging; Stress induced premature senescence (SIPS); UVB

Indexed keywords

BETA GALACTOSIDASE; INTERSTITIAL COLLAGENASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL DEATH; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PHOTOAGING; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RADIATION EXPOSURE; SENESCENCE; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; ULTRAVIOLET B RADIATION;

DERMAL FIBROBLAST; PHOTOAGING; STRESS-INDUCED PREMATURE SENESCENCE (SIPS); UVB;

ANIMALS; APOPTOSIS; CELL AGING; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, RADIATION; EXTRACELLULAR MATRIX; FIBROBLASTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PHENOTYPE; REACTIVE OXYGEN SPECIES; SKIN; SKIN AGING; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 84890119555     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.08.013     Document Type: Article

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