Effects of macelignan isolated from Myristica fragrans Houtt. on UVB-induced matrix metalloproteinase-9 and cyclooxygenase-2 in HaCaT cells

Journal of Dermatological Science

Volumn 57, Issue 2, 2010, Pages 114-122

  Anggakusuma, ^a   Yanti, ^a,b   Hwang, Jae Kwan ^a  

^a Yonsei University   (South Korea)

^b ATMA JAYA CATHOLIC UNIVERSITY OF INDONESIA   (Indonesia)

Author keywords

COX 2; HaCaT cells; Macelignan; MAPK pathway; MMP 9; PI3K Akt pathway; UVB irradiation

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; GELATINASE B; LIGNAN DERIVATIVE; MACELIGNAN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HUMAN; HUMAN CELL; KERATINOCYTE; NUTMEG; PHOTOAGING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION INJURY; SIGNAL TRANSDUCTION; SKIN CULTURE; SKIN DISEASE; SKIN INFLAMMATION; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; ZYMOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE, TRANSFORMED; CELL SURVIVAL; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; ENZYME ACTIVATION; HUMANS; INFLAMMATION; KERATINOCYTES; LIGNANS; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; MYRISTICA FRAGRANS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 74749089783     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2009.10.005     Document Type: Article

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