Mitogen-activated protein kinase phosphatase-1 inhibition and sustained extracellular signal-regulated kinase 1/2 activation in camptothecin-induced human colon cancer cell death

Cancer Biology and Therapy

Volumn 14, Issue 11, 2013, Pages 1007-1015

  Lee, Minyoung ^a   Kim, Sun Young ^a   Kim, Jong Guk ^a   Kim, Hak Su ^b   Kim, Sang Man ^c   Kim, Eun Ju ^a,c  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Camptothecin; ERK; Human colon cancer; MKP1

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CAMPTOTHECIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PHOSPHATASE;

ARTICLE; CELL DEATH; CELL STRAIN HCT116; COLON CANCER; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

CAMPTOTHECIN; ERK; HUMAN COLON CANCER; MKP1;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CACO-2 CELLS; CAMPTOTHECIN; COLONIC NEOPLASMS; DUAL SPECIFICITY PHOSPHATASE 1; ENZYME ACTIVATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 84890101796     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.26044     Document Type: Article

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