메뉴 건너뛰기




Volumn 10, Issue 4, 2010, Pages 354-361

Janus-activated kinases and signal transducer and activator of transcription control tumor growth response to camptothecin in human colon cancer cells

Author keywords

Apoptosis; Camptothecin; Colon cancer; CPT; JAK; Janus activated kinases; Signal transducer and activator of transcription; STAT

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE; JANUS KINASE 2; STAT3 PROTEIN;

EID: 77957137452     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.4.12382     Document Type: Article
Times cited : (16)

References (39)
  • 2
    • 10844223742 scopus 로고    scopus 로고
    • Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL
    • Ravi R, Jain AJ, Schulick RD, Pham V, Prouser TS, Allen H, et al. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. Cancer Res 2004; 64:9105-14.
    • (2004) Cancer Res , vol.64 , pp. 9105-9114
    • Ravi, R.1    Jain, A.J.2    Schulick, R.D.3    Pham, V.4    Prouser, T.S.5    Allen, H.6
  • 3
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE Jr. STATs and gene regulation. Science 1997; 277:1630-5.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 5
    • 0034306290 scopus 로고    scopus 로고
    • STAT proteins and transcriptional responses to extracellular signals
    • Horvath CM. STAT proteins and transcriptional responses to extracellular signals. Trends Biochem Sci 2000; 25:496-502.
    • (2000) Trends Biochem Sci , vol.25 , pp. 496-502
    • Horvath, C.M.1
  • 6
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • Turkson J, Jove R. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 2000; 19:6613-26.
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 7
    • 33947574564 scopus 로고    scopus 로고
    • Targeting signal-transducer- and-activator-of-transcription-3 for prevention and therapy of cancer: Modern target but ancient solution
    • Aggarwal BB, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, et al. Targeting signal-transducer- and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann N Y Acad Sci 2006; 1091:151-69.
    • (2006) Ann N Y Acad Sci , vol.1091 , pp. 151-169
    • Aggarwal, B.B.1    Sethi, G.2    Ahn, K.S.3    Sandur, S.K.4    Pandey, M.K.5    Kunnumakkara, A.B.6
  • 8
    • 58249119435 scopus 로고    scopus 로고
    • Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells
    • Shin DS, Kim HN, Shin KD, Yoon YJ, Kim SJ, Han DC, Kwon BM. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells. Cancer Res 2009; 69:193-202.
    • (2009) Cancer Res , vol.69 , pp. 193-202
    • Shin, D.S.1    Kim, H.N.2    Shin, K.D.3    Yoon, Y.J.4    Kim, S.J.5    Han, D.C.6    Kwon, B.M.7
  • 9
    • 67650995911 scopus 로고    scopus 로고
    • Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells
    • Thoennissen NH, Iwanski GB, Doan NB, Okamoto R, Lin P, Abbassi S, et al. Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells. Cancer Res 2009; 69:5876-84.
    • (2009) Cancer Res , vol.69 , pp. 5876-5884
    • Thoennissen, N.H.1    Iwanski, G.B.2    Doan, N.B.3    Okamoto, R.4    Lin, P.5    Abbassi, S.6
  • 10
    • 0030978808 scopus 로고    scopus 로고
    • Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
    • Nielsen M, Kaltoft K, Nordahl M, Ropke C, Geisler C, Mustelin T, et al. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc Natl Acad Sci USA 1997; 94:6764-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6764-6769
    • Nielsen, M.1    Kaltoft, K.2    Nordahl, M.3    Ropke, C.4    Geisler, C.5    Mustelin, T.6
  • 11
    • 0027194943 scopus 로고
    • Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
    • CPT-11 Gastrointestinal Cancer Study Group
    • Shimada Y, Yoshino M, Wakui A, Nakao I, Futatsuki K, Sakata Y, et al. Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group. J Clin Oncol 1993; 11:909-13.
    • (1993) J Clin Oncol , vol.11 , pp. 909-913
    • Shimada, Y.1    Yoshino, M.2    Wakui, A.3    Nakao, I.4    Futatsuki, K.5    Sakata, Y.6
  • 12
    • 10744233671 scopus 로고    scopus 로고
    • Repair of and checkpoint response to topoisomerase I-mediated DNA damage
    • Pommier Y, Redon C, Rao VA, Seiler JA, Sordet O, Takemura H, et al. Repair of and checkpoint response to topoisomerase I-mediated DNA damage. Mutat Res 2003; 532:173-203.
    • (2003) Mutat Res , vol.532 , pp. 173-203
    • Pommier, Y.1    Redon, C.2    Rao, V.A.3    Seiler, J.A.4    Sordet, O.5    Takemura, H.6
  • 13
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Camptothecins and beyond
    • Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 2006; 6:789-802.
    • (2006) Nat Rev Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 14
    • 0026575901 scopus 로고
    • Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells
    • Aller P, Rius C, Mata F, Zorrilla A, Cabanas C, Bellon T, Bernabeu C. Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells. Cancer Res 1992; 52:1245-51.
    • (1992) Cancer Res , vol.52 , pp. 1245-1251
    • Aller, P.1    Rius, C.2    Mata, F.3    Zorrilla, A.4    Cabanas, C.5    Bellon, T.6    Bernabeu, C.7
  • 18
    • 0037637701 scopus 로고    scopus 로고
    • MAPK signaling is involved in camptothecin-induced cell death
    • Lee S, Lee HS, Baek M, Lee DY, Bang YJ, Cho HN, et al. MAPK signaling is involved in camptothecin-induced cell death. Mol Cells 2002; 14:348-54.
    • (2002) Mol Cells , vol.14 , pp. 348-354
    • Lee, S.1    Lee, H.S.2    Baek, M.3    Lee, D.Y.4    Bang, Y.J.5    Cho, H.N.6
  • 21
    • 0037086088 scopus 로고    scopus 로고
    • Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: Microarray analysis of dose- and time-dependent effects
    • Zhou Y, Gwadry FG, Reinhold WC, Miller LD, Smith LH, Scherf U, et al. Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: microarray analysis of dose- and time-dependent effects. Cancer Res 2002; 62:1688-95.
    • (2002) Cancer Res , vol.62 , pp. 1688-1695
    • Zhou, Y.1    Gwadry, F.G.2    Reinhold, W.C.3    Miller, L.D.4    Smith, L.H.5    Scherf, U.6
  • 22
    • 0033208192 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Selectivity and cellular resistance
    • DOI 10.1054/drup.1999.0102
    • Pommier Y, Pourquier P, Urasaki Y, Wu J, Laco GS. Topoisomerase I inhibitors: selectivity and cellular resistance. Drug Resist Updat 1999; 2:307-18. (Pubitemid 30070455)
    • (1999) Drug Resistance Updates , vol.2 , Issue.5 , pp. 307-318
    • Pommier, Y.1    Pourquier, P.2    Urasaki, Y.3    Wu, J.4    Laco, G.S.5
  • 23
    • 34548549283 scopus 로고    scopus 로고
    • Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer
    • Berishaj M, Gao SP, Ahmed S, Leslie K, Al-Ahmadie H, Gerald WL, et al. Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. Breast Cancer Res 2007; 9:32.
    • (2007) Breast Cancer Res , vol.9 , pp. 32
    • Berishaj, M.1    Gao, S.P.2    Ahmed, S.3    Leslie, K.4    Al-Ahmadie, H.5    Gerald, W.L.6
  • 24
    • 0033539651 scopus 로고    scopus 로고
    • Chromosomal aberrations in PARP(-/-) mice: Genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA
    • Simbulan-Rosenthal CM, Haddad BR, Rosenthal DS, Weaver Z, Coleman A, Luo R, et al. Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA. Proc Natl Acad Sci USA 1999; 96:13191-6.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13191-13196
    • Simbulan-Rosenthal, C.M.1    Haddad, B.R.2    Rosenthal, D.S.3    Weaver, Z.4    Coleman, A.5    Luo, R.6
  • 25
    • 0029869176 scopus 로고    scopus 로고
    • The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFNalpha signals
    • Gupta S, Yan H, Wong LH, Ralph S, Krolewski J, Schindler C. The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFNalpha signals. EMBO J 1996; 15:1075-84.
    • (1996) EMBO J , vol.15 , pp. 1075-1084
    • Gupta, S.1    Yan, H.2    Wong, L.H.3    Ralph, S.4    Krolewski, J.5    Schindler, C.6
  • 26
    • 0030804219 scopus 로고    scopus 로고
    • The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs)
    • Pellegrini S, Dusanter-Fourt I. The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs). Eur J Biochem 1997; 248:615-33. (Pubitemid 27400015)
    • (1997) European Journal of Biochemistry , vol.248 , Issue.3 , pp. 615-633
    • Pellegrini, S.1    Dusanter-Fourt, I.2
  • 27
    • 0038167666 scopus 로고    scopus 로고
    • The camptothecins
    • Pizzolato JF, Saltz LB. The camptothecins. Lancet 2003; 361:2235-42.
    • (2003) Lancet , vol.361 , pp. 2235-2242
    • Pizzolato, J.F.1    Saltz, L.B.2
  • 29
    • 0028267240 scopus 로고
    • Camptothecins: From bench research to hospital wards
    • Potmesil M. Camptothecins: from bench research to hospital wards. Cancer Res 1994; 54:1431-9.
    • (1994) Cancer Res , vol.54 , pp. 1431-1439
    • Potmesil, M.1
  • 31
    • 0031046059 scopus 로고    scopus 로고
    • CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinants
    • Jansen WJ, Zwart B, Hulscher ST, Giaccone G, Pinedo HM, Boven E. CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants. Int J Cancer 1997; 70:335-40.
    • (1997) Int J Cancer , vol.70 , pp. 335-340
    • Jansen, W.J.1    Zwart, B.2    Hulscher, S.T.3    Giaccone, G.4    Pinedo, H.M.5    Boven, E.6
  • 32
    • 0029029436 scopus 로고
    • Topoisomerase I-related parameters and camptothecin activity in the colon carcinoma cell lines from the National Cancer Institute anticancer screen
    • Goldwasser F, Bae I, Valenti M, Torres K, Pommier Y. Topoisomerase I-related parameters and camptothecin activity in the colon carcinoma cell lines from the National Cancer Institute anticancer screen. Cancer Res 1995; 55:2116-21.
    • (1995) Cancer Res , vol.55 , pp. 2116-2121
    • Goldwasser, F.1    Bae, I.2    Valenti, M.3    Torres, K.4    Pommier, Y.5
  • 33
    • 0028067913 scopus 로고
    • Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types
    • DOI 10.1097/00001813-199412000-00006
    • Perego P, Capranico G, Supino R, Zunino F. Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types. Anticancer Drugs 1994; 5:645-9. (Pubitemid 24381882)
    • (1994) Anti-Cancer Drugs , vol.5 , Issue.6 , pp. 645-649
    • Perego, P.1    Capranico, G.2    Supino, R.3    Zunino, F.4
  • 35
    • 7444238184 scopus 로고    scopus 로고
    • Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis in vitro and in vivo in prostate cancer cell lines
    • Barton BE, Murphy TF, Shu P, Huang HF, Meyenhofer M, Barton A. Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis in vitro and in vivo in prostate cancer cell lines. Mol Cancer Ther 2004; 3:1183-91.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1183-1191
    • Barton, B.E.1    Murphy, T.F.2    Shu, P.3    Huang, H.F.4    Meyenhofer, M.5    Barton, A.6
  • 36
    • 20844444135 scopus 로고    scopus 로고
    • Targeting Stat3 in cancer therapy
    • Jing N, Tweardy DJ. Targeting Stat3 in cancer therapy. Anticancer Drugs 2005; 16:601-7.
    • (2005) Anticancer Drugs , vol.16 , pp. 601-607
    • Jing, N.1    Tweardy, D.J.2
  • 37
    • 29144528036 scopus 로고    scopus 로고
    • STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells
    • Bhattacharya S, Ray RM, Johnson LR. STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. Biochem J 2005; 392:335-44.
    • (2005) Biochem J , vol.392 , pp. 335-344
    • Bhattacharya, S.1    Ray, R.M.2    Johnson, L.R.3
  • 38
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74:597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3    Ding, L.4    Lindsten, T.5    Turka, L.A.6
  • 39
    • 33749475259 scopus 로고    scopus 로고
    • Inhibition of the Janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication
    • DOI 10.1158/0008-5472.CAN-06-0972
    • Reiterer G, Yen A. Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Res 2006; 66:9083-9. (Pubitemid 44521127)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9083-9089
    • Reiterer, G.1    Yen, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.