A modular system for the synthesis of multiplexed magnetic resonance probes

Journal of the American Chemical Society

Volumn 133, Issue 14, 2011, Pages 5329-5337

  Mastarone, Daniel J ^a   Harrison, Victoria S R ^a   Eckermann, Amanda L ^a   Parigi, Giacomo ^b   Luchinat, Claudio ^b   Meade, Thomas J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLICK CHEMISTRY; CONTRAST AGENT; LANTHANIDES; MAGNETIC RESONANCE DISPERSIONS; MODULAR ARCHITECTURES; MODULAR SYSTEM; RELAXIVITY; ROTATIONAL CORRELATION TIME; SMALL MOLECULES;

CHELATION; FUNCTIONAL GROUPS; GADOLINIUM; MAGNETIC RESONANCE; MULTIPLEXING; PROBES; SCAFFOLDS;

CRYSTAL STRUCTURE;

1 (3 AZIDO 2 HYDROXYPROPYL) 4,7,10 TRIS(CARBOXYMETHYL) 1,4,7,10 TETRAAZACYCLODODECYL GD; 1 AZIDO 3 CHLOROPROPAN 2 OL; 5 (2,4,6 TRIETHYNYLPHENOXY)PENTANOIC ACID; 5 [2,4,6 TRIS[1 [2 HYDROXY 3 (1H 1,2,3 TRIAZOL 1 YL)PROPYL] 4,7,10 TRIS(CARBOXYMETHYL) 1,4,7,10 TETRAAZACYCLODODECYLGADOLINIUM(III)]PHENOXY]PENTANOIC ACID; AZIDE; CHELATE; ETHYL 5 (2,4,6 TRIBROMOPHENOXY)PENTANOATE; ETHYL 5 (2,4,6 TRIETHYNYLPHENOXY)PENTANOATE; ETHYL 5 [2,4,6 TRIS[(TRIMETHYLSILYL)ETHYNYL]PHENOXY]PENTANOATE; ETHYL 5 [2,4,6 TRIS[1 [2 [[2 (1H 1,2,3 TRIAZOL 1 YL)ETHYL]AMINO] 2 OXOETHYL] 4,7,10 TRIS(CARBOXYMETHYL) 1,4,7,10 TETRAAZACYCLODODECYLGADOLINIUM(III)]PHENOXY]PENTANOATE; ETHYL 5 [2,4,6 TRIS[1 [2 [[2 (1H 1,2,3 TRIAZOL 1 YL)PROPYL]AMINO] 2 OXOETHYL] 4,7,10 TRIS(CARBOXYMETHYL) 1,4,7,10 TETRAAZACYCLODODECYLGADOLINIUM(III)]PHENOXY]PENTANOATE; GADOLINIUM CHELATE; LANTHANIDE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; SMALL MOLECULE TRANSPORT AGENT; TRITERT BUTYL 2,2',2'' (1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL)TRIACETATE HYDROBROMIDE; TRITERT BUTYL 2,2',2'' (10 (3 AZIDO 2 HYDROXYPROPYL) 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL)TRIACETATE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DISPERSION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR PROBE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

ALKYNES; AZIDES; CHELATING AGENTS; CLICK CHEMISTRY; CONTRAST MEDIA; DRUG DESIGN; GADOLINIUM; MAGNETIC RESONANCE IMAGING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; ORGANOMETALLIC COMPOUNDS; TEMPERATURE;

EID: 79953697121     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1099616     Document Type: Article

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