Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy

Biosensors and Bioelectronics

Volumn 54, Issue , 2014, Pages 492-498

  Hane, Francis T ^a   Lee, Brenda Y ^a   Petoyan, Anahit ^b   Rauk, Arvi ^b   Leonenko, Zoya ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Aggregation inhibitor; Alzheimer's disease; Amyloid aggregation; Fibril formation; Molecular dynamics simulations; Single molecule force spectroscopy

Indexed keywords

ATOMS; MOLECULAR DYNAMICS; MOLECULES; NEURODEGENERATIVE DISEASES; PEPTIDES;

AGGREGATION INHIBITORS; ALZHEIMER'S DISEASE; FIBRIL FORMATION; MOLECULAR DYNAMICS SIMULATIONS; SINGLE MOLECULE FORCE SPECTROSCOPY;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN[1-42]; PSEUDOPEPTIDE;

ARTICLE; ATOMIC FORCE MICROSCOPY; BETA SHEET; CONTROLLED STUDY; DRUG EFFICACY; MOLECULAR RECOGNITION; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN FOLDING; SCREENING TEST;

AGGREGATION INHIBITOR; ALZHEIMER'S DISEASE; AMYLOID-Β AGGREGATION; FIBRIL FORMATION; MOLECULAR DYNAMICS SIMULATIONS; SINGLE MOLECULE FORCE SPECTROSCOPY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BIOSENSING TECHNIQUES; DRUG EVALUATION, PRECLINICAL; HUMANS; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION;

EID: 84890073064     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2013.10.060     Document Type: Article

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