메뉴 건너뛰기




Volumn , Issue , 2008, Pages 193-221

Galectin-3 in the Progression and Metastasis of Colorectal Neoplasia

Author keywords

Colon cancer mucin galectin 3 interaction; Colorectal neoplasia galectin 3 metastasis; Galectin 3 Ser6 phosphorylation

Indexed keywords


EID: 84889830424     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470378076.ch10     Document Type: Chapter
Times cited : (5)

References (101)
  • 1
    • 0029073986 scopus 로고
    • Expression of an endogenous galactosebinding lectin correlates with neoplastic progression in the colon
    • Schoeppner HL, Raz A, Ho SB, Bresalier RS. Expression of an endogenous galactosebinding lectin correlates with neoplastic progression in the colon. Cancer 1995;75: 2818-2826.
    • (1995) Cancer , vol.75 , pp. 2818-2826
    • Schoeppner, H.L.1    Raz, A.2    Ho, S.B.3    Bresalier, R.S.4
  • 3
    • 30744436834 scopus 로고    scopus 로고
    • Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa
    • Holt PR, Bresalier RS, Ma CK, Liu KF, Lipkin M, Byrd JC, Yang K. Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa. Cancer 2006;106:287-296.
    • (2006) Cancer , vol.106 , pp. 287-296
    • Holt, P.R.1    Bresalier, R.S.2    Ma, C.K.3    Liu, K.F.4    Lipkin, M.5    Byrd, J.C.6    Yang, K.7
  • 4
    • 0029782551 scopus 로고    scopus 로고
    • Colon cancer mucin: a new ligand for the betagalactoside- binding protein galectin-3
    • Bresalier RS, Byrd JC, Wang L, Raz A. Colon cancer mucin: a new ligand for the betagalactoside- binding protein galectin-3. Cancer Res 1996;56:4354-4357.
    • (1996) Cancer Res , vol.56 , pp. 4354-4357
    • Bresalier, R.S.1    Byrd, J.C.2    Wang, L.3    Raz, A.4
  • 5
    • 0034680933 scopus 로고    scopus 로고
    • Phosphorylation of the betagalactoside- binding protein galectin-3 modulates binding to its ligands
    • Mazurek N, Conklin J, Byrd JC, Raz A, Bresalier RS. Phosphorylation of the betagalactoside- binding protein galectin-3 modulates binding to its ligands. J Biol Chem 2000;275:36311-36315.
    • (2000) J Biol Chem , vol.275 , pp. 36311-36315
    • Mazurek, N.1    Conklin, J.2    Byrd, J.C.3    Raz, A.4    Bresalier, R.S.5
  • 6
    • 0036727315 scopus 로고    scopus 로고
    • Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer
    • Dudas SP, Yunker CK, Sternberg LR, Byrd JC, Bresalier RS. Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer. Gastroenterology 2002;123:817-826.
    • (2002) Gastroenterology , vol.123 , pp. 817-826
    • Dudas, S.P.1    Yunker, C.K.2    Sternberg, L.R.3    Byrd, J.C.4    Bresalier, R.S.5
  • 7
    • 27744493218 scopus 로고    scopus 로고
    • Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation
    • Song S, Byrd JC, Mazurek N, Liu K, Koo JS, Bresalier RS. Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation. Gastroenterology 2005;129:1581-1591.
    • (2005) Gastroenterology , vol.129 , pp. 1581-1591
    • Song, S.1    Byrd, J.C.2    Mazurek, N.3    Liu, K.4    Koo, J.S.5    Bresalier, R.S.6
  • 8
    • 0033572093 scopus 로고    scopus 로고
    • The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells
    • Gong HC, Honjo Y, Nangia-Makker P, Hogan V, Mazurak N, Bresalier RS, Raz A. The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells. Cancer Res 1999;59:6239-6245.
    • (1999) Cancer Res , vol.59 , pp. 6239-6245
    • Gong, H.C.1    Honjo, Y.2    Nangia-Makker, P.3    Hogan, V.4    Mazurak, N.5    Bresalier, R.S.6    Raz, A.7
  • 9
    • 2942591023 scopus 로고    scopus 로고
    • Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs
    • Takenaka Y, Fukumori T, Yoshii T, Oka N, Inohara H, Kim HR, Bresalier RS, Raz A. Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol Cell Biol 2004;24:4395-4406.
    • (2004) Mol Cell Biol , vol.24 , pp. 4395-4406
    • Takenaka, Y.1    Fukumori, T.2    Yoshii, T.3    Oka, N.4    Inohara, H.5    Kim, H.R.6    Bresalier, R.S.7    Raz, A.8
  • 10
    • 28244475784 scopus 로고    scopus 로고
    • Phosphorylation of galectin-3 contributes to malignant transformation of human epithelial cells via modulation of unique sets of genes
    • Mazurek N, Sun YJ, Price JE, Ramdas L, SchoberW, Nangia-Makker P, Byrd JC, Raz A, Bresalier RS. Phosphorylation of galectin-3 contributes to malignant transformation of human epithelial cells via modulation of unique sets of genes. Cancer Res 2005;65:10767-10775.
    • (2005) Cancer Res , vol.65 , pp. 10767-10775
    • Mazurek, N.1    Sun, Y.J.2    Price, J.E.3    Ramdas, L.4    Schober, W.5    Nangia-Makker, P.6    Byrd, J.C.7    Raz, A.8    Bresalier, R.S.9
  • 11
    • 34547131862 scopus 로고    scopus 로고
    • Phosphorylated galectin-3 mediates tumor necrosis factor-related apoptosis-inducing ligand signaling by regulating phosphatase and tensin homologue deleted on chromosome 10 in human breast carcinoma cells
    • Mazurek N, Sun YJ, Liu KF, Gilcrease MZ, Schober W, Nangia-Makker P, Raz A, Bresalier RS. Phosphorylated galectin-3 mediates tumor necrosis factor-related apoptosis-inducing ligand signaling by regulating phosphatase and tensin homologue deleted on chromosome 10 in human breast carcinoma cells. J Biol Chem 2007;282: 21337-21348.
    • (2007) J Biol Chem , vol.282 , pp. 21337-21348
    • Mazurek, N.1    Sun, Y.J.2    Liu, K.F.3    Gilcrease, M.Z.4    Schober, W.5    Nangia-Makker, P.6    Raz, A.7    Bresalier, R.S.8
  • 13
    • 84889812952 scopus 로고    scopus 로고
    • Expression of galectin-3 and its binding protein (Mac-2-BP) correlate with progression and metastasis of colorectal adenocarcinoma
    • Liu K, Byrd JC, Song S, Bresalier RS. Expression of galectin-3 and its binding protein (Mac-2-BP) correlate with progression and metastasis of colorectal adenocarcinoma. Gastroenterology 2006;130:A88.
    • (2006) Gastroenterology , vol.130
    • Liu, K.1    Byrd, J.C.2    Song, S.3    Bresalier, R.S.4
  • 14
    • 0037132694 scopus 로고    scopus 로고
    • Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin
    • Nangia-Makker P, Hogan V, Honjo Y, Baccarini S, Tait L, Bresalier R, Raz A. Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J Natl Cancer Inst 2002;94:1854-1862.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1854-1862
    • Nangia-Makker, P.1    Hogan, V.2    Honjo, Y.3    Baccarini, S.4    Tait, L.5    Bresalier, R.6    Raz, A.7
  • 15
    • 0037136416 scopus 로고    scopus 로고
    • Galectinomics: finding themes in complexity
    • Cooper DNW. Galectinomics: finding themes in complexity. Biochim Biophys Acta 2002;1572:209-231.
    • (2002) Biochim Biophys Acta , vol.1572 , pp. 209-231
    • Cooper, D.N.W.1
  • 16
    • 0027414461 scopus 로고
    • Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma
    • Lotz MM, Andrews CW, Korzelius CA, Lee EC, Steele, Clarke A, Mercurio AM. Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc Natl Acad Sci USA 1993;90:3466-3470.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3466-3470
    • Lotz, M.M.1    Andrews, C.W.2    Korzelius, C.A.3    Lee, E.C.4    Steele5    Clarke, A.6    Mercurio, A.M.7
  • 18
    • 0027310193 scopus 로고
    • Structure-function relationship of a recombinant human galactoside-binding protein
    • Ochieng J, Platt D, Tait L, Hogan V, Raz T, Carmi P, Raz A. Structure-function relationship of a recombinant human galactoside-binding protein. Biochemistry 1993; 32:4455-4460.
    • (1993) Biochemistry , vol.32 , pp. 4455-4460
    • Ochieng, J.1    Platt, D.2    Tait, L.3    Hogan, V.4    Raz, T.5    Carmi, P.6    Raz, A.7
  • 19
    • 0023488847 scopus 로고
    • Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis
    • Raz A, Lotan R. Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis. Cancer Metastasis Rev 1987;6: 433-452.
    • (1987) Cancer Metastasis Rev , vol.6 , pp. 433-452
    • Raz, A.1    Lotan, R.2
  • 21
    • 0037013214 scopus 로고    scopus 로고
    • Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation
    • Yu F, Finley Jr RL, Raz A, Kim HR. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem 2002;277:15819-15827.
    • (2002) J Biol Chem , vol.277 , pp. 15819-15827
    • Yu, F.1    Finley Jr, R.L.2    Raz, A.3    Kim, H.R.4
  • 25
    • 84889871417 scopus 로고
    • An animal model for colon cancer metastasis. Establishment and characterization of murine colon cancer cell lines with enhanced liver-metastazing ability
    • Bresalier RS, Hujanen ES, Raper SE, Roll FJ, Itzkowitz SH, Martin GR, Kim YS. An animal model for colon cancer metastasis. Establishment and characterization of murine colon cancer cell lines with enhanced liver-metastazing ability. Cancer Res 1985;47: 249-260.
    • (1985) Cancer Res , vol.47 , pp. 249-260
    • Bresalier, R.S.1    Hujanen, E.S.2    Raper, S.E.3    Roll, F.J.4    Itzkowitz, S.H.5    Martin, G.R.6    Kim, Y.S.7
  • 27
    • 0025169654 scopus 로고
    • Cell surface sialoprotein alterations in metastatic murine colon cancer cell lines selected in an animal model for colon cancer metastasis
    • Bresalier RS, Rockwell RW, Dahiya R, Duh Q-Y, Kim YS. Cell surface sialoprotein alterations in metastatic murine colon cancer cell lines selected in an animal model for colon cancer metastasis. Cancer Res 1990;50:1299-1307.
    • (1990) Cancer Res , vol.50 , pp. 1299-1307
    • Bresalier, R.S.1    Rockwell, R.W.2    Dahiya, R.3    Duh, Q.-Y.4    Kim, Y.S.5
  • 28
    • 0025778637 scopus 로고
    • Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis
    • Bresalier RS, Niv Y, Byrd JC, Duh Q, Toribara NW, Kim YS. Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis. J Clin Invest 1991;87:1037-1045.
    • (1991) J Clin Invest , vol.87 , pp. 1037-1045
    • Bresalier, R.S.1    Niv, Y.2    Byrd, J.C.3    Duh, Q.4    Toribara, N.W.5    Kim, Y.S.6
  • 29
    • 0029016270 scopus 로고
    • Immunolocalization of hepatic metastases of human colonic cancer by chimeric anti-AG72 antibody in SCID mice
    • Qi Y, Moyana T, Matte G, Wilkinson A, Bresalier RS, Xiang J. Immunolocalization of hepatic metastases of human colonic cancer by chimeric anti-AG72 antibody in SCID mice. J Surg Oncol 1995;8:3-9.
    • (1995) J Surg Oncol , vol.8 , pp. 3-9
    • Qi, Y.1    Moyana, T.2    Matte, G.3    Wilkinson, A.4    Bresalier, R.S.5    Xiang, J.6
  • 30
    • 0028851708 scopus 로고
    • Antibody targeted lymphokine-activated killer cells inhibit liver micrometastases in severe combined immunodeficient mice
    • Qi Y, Moyana T, Bresalier RS, Xiang J. Antibody targeted lymphokine-activated killer cells inhibit liver micrometastases in severe combined immunodeficient mice. Gastroenterology 1995;109:1950-1957.
    • (1995) Gastroenterology , vol.109 , pp. 1950-1957
    • Qi, Y.1    Moyana, T.2    Bresalier, R.S.3    Xiang, J.4
  • 31
    • 0028978119 scopus 로고
    • The laminin (a1 chain Ile-Lys-Val-Ala-Val (IKVA)-containing peptide promotes liver colonization by human colon cancer cells
    • Bresalier RS, Schwartz B, Kim YS, Duh Q-Y, Kleinman HK, Sullam PM. The laminin (a1 chain Ile-Lys-Val-Ala-Val (IKVA)-containing peptide promotes liver colonization by human colon cancer cells. Cancer Res 1995;55:2476-2480.
    • (1995) Cancer Res , vol.55 , pp. 2476-2480
    • Bresalier, R.S.1    Schwartz, B.2    Kim, Y.S.3    Duh, Q.-Y.4    Kleinman, H.K.5    Sullam, P.M.6
  • 32
    • 0032903756 scopus 로고    scopus 로고
    • Liver colonization by human colon cancer cells is reduced by antisense inhibition of MUC2 mucin synthesis
    • Sternberg LR, Byrd JC, Yunker CK, Dudas S, Hoon V, Bresalier RS. Liver colonization by human colon cancer cells is reduced by antisense inhibition of MUC2 mucin synthesis. Gastroenterology 1999;116:363-371.
    • (1999) Gastroenterology , vol.116 , pp. 363-371
    • Sternberg, L.R.1    Byrd, J.C.2    Yunker, C.K.3    Dudas, S.4    Hoon, V.5    Bresalier, R.S.6
  • 33
    • 1242337458 scopus 로고    scopus 로고
    • Mucins and mucin binding proteins in colorectal cancer
    • Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev 2004;23:77-99.
    • (2004) Cancer Metastasis Rev , vol.23 , pp. 77-99
    • Byrd, J.C.1    Bresalier, R.S.2
  • 34
    • 0036676199 scopus 로고    scopus 로고
    • Intestinal mucin and colon cancer
    • Bresalier RS. Intestinal mucin and colon cancer. Gastroenterology 2002;123:648-649.
    • (2002) Gastroenterology , vol.123 , pp. 648-649
    • Bresalier, R.S.1
  • 35
    • 33745177351 scopus 로고    scopus 로고
    • Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases
    • Andrianifahanana M, Moniaux N, Batra SK. Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. Biochim Biophys Acta 2006;1765:189-222.
    • (2006) Biochim Biophys Acta , vol.1765 , pp. 189-222
    • Andrianifahanana, M.1    Moniaux, N.2    Batra, S.K.3
  • 36
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: protection and control of the cell surface
    • Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004;4:45-60.
    • (2004) Nat Rev Cancer , vol.4 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 37
    • 0030015828 scopus 로고    scopus 로고
    • Significance of MUC1 and MUC2 mucin expression in colorectal cancer
    • Ajioka Y, Allison LJ, Jass JR. Significance of MUC1 and MUC2 mucin expression in colorectal cancer. J Clin Pathol 1996;49:560-564.
    • (1996) J Clin Pathol , vol.49 , pp. 560-564
    • Ajioka, Y.1    Allison, L.J.2    Jass, J.R.3
  • 39
    • 0026474723 scopus 로고
    • Mucin gene expression in colonic tissues and cell lines
    • Ogata S, Uehara H, Chen A, Itzkowitz SH. Mucin gene expression in colonic tissues and cell lines. Cancer Res 1992;52:5971-5978.
    • (1992) Cancer Res , vol.52 , pp. 5971-5978
    • Ogata, S.1    Uehara, H.2    Chen, A.3    Itzkowitz, S.H.4
  • 43
    • 0029840759 scopus 로고    scopus 로고
    • Expression of MUC2 and MUC3 mRNA in human normal, malignant and inflammatory tissues
    • Weiss AA, Babyatsky MW, Ogata S, Chen A, Itzkowitz SH. Expression of MUC2 and MUC3 mRNA in human normal, malignant and inflammatory tissues. J Histochem Cytochem 1996;44:1161-1166.
    • (1996) J Histochem Cytochem , vol.44 , pp. 1161-1166
    • Weiss, A.A.1    Babyatsky, M.W.2    Ogata, S.3    Chen, A.4    Itzkowitz, S.H.5
  • 46
    • 0343962992 scopus 로고    scopus 로고
    • Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis
    • Biemer-Huttmann AE, Walsh MD, McGuckin MA, Simms LA, Young J, Leggett BA, Jass JR. Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin Cancer Res 2000;6:1909-1916.
    • (2000) Clin Cancer Res , vol.6 , pp. 1909-1916
    • Biemer-Huttmann, A.E.1    Walsh, M.D.2    McGuckin, M.A.3    Simms, L.A.4    Young, J.5    Leggett, B.A.6    Jass, J.R.7
  • 47
    • 0033765156 scopus 로고    scopus 로고
    • Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomas
    • Manne U, Weiss HL, Grizzle WE. Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomas. Clin Cancer Res 2000;6:4017-4025.
    • (2000) Clin Cancer Res , vol.6 , pp. 4017-4025
    • Manne, U.1    Weiss, H.L.2    Grizzle, W.E.3
  • 52
    • 0031979657 scopus 로고    scopus 로고
    • Liver metastasis and adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate chain length
    • Bresalier RS, Byrd JC, Brodt P, Ogata S, Yunker C. Liver metastasis and adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate chain length. Int J Cancer 1998;76:556-562.
    • (1998) Int J Cancer , vol.76 , pp. 556-562
    • Bresalier, R.S.1    Byrd, J.C.2    Brodt, P.3    Ogata, S.4    Yunker, C.5
  • 54
    • 0027527552 scopus 로고
    • L-29, a soluble lactosebinding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I
    • Huflejt ME, Turck CW, Lindstedt R, Barondes SH, Leffler H. L-29, a soluble lactosebinding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I. J Biol Chem 1993;268:26712-26718.
    • (1993) J Biol Chem , vol.268 , pp. 26712-26718
    • Huflejt, M.E.1    Turck, C.W.2    Lindstedt, R.3    Barondes, S.H.4    Leffler, H.5
  • 55
    • 0026002649 scopus 로고
    • Expression of carbohydrate binding protein 35 in human fibroblasts variations in the levels of mRNA, protein, and isoelectric species as a function of replicative competence
    • Hamann KK, Cowles EA, Wang JL, Anderson RL. Expression of carbohydrate binding protein 35 in human fibroblasts variations in the levels of mRNA, protein, and isoelectric species as a function of replicative competence. Exp Cell Res 1991;196:82-91.
    • (1991) Exp Cell Res , vol.196 , pp. 82-91
    • Hamann, K.K.1    Cowles, E.A.2    Wang, J.L.3    Anderson, R.L.4
  • 56
    • 0025173330 scopus 로고
    • Carbohydrate-binding protein 35. Isoelectric points of the polypeptide and a phosphorylated derivative
    • Cowles EA, Agrwal N, Anderson RL, Wang JL. Carbohydrate-binding protein 35. Isoelectric points of the polypeptide and a phosphorylated derivative. J Biol Chem 1990;265:17706-17712.
    • (1990) J Biol Chem , vol.265 , pp. 17706-17712
    • Cowles, E.A.1    Agrwal, N.2    Anderson, R.L.3    Wang, J.L.4
  • 58
    • 0036510564 scopus 로고    scopus 로고
    • Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest
    • Yoshi T, Fukumori T, Honjo Y, Inohara H, Kim HRC, Raz A. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. J Biol Chem 2002;277:6852-6857.
    • (2002) J Biol Chem , vol.277 , pp. 6852-6857
    • Yoshi, T.1    Fukumori, T.2    Honjo, Y.3    Inohara, H.4    Kim, H.R.C.5    Raz, A.6
  • 59
    • 0031885334 scopus 로고    scopus 로고
    • Evidence for subsites in the galectins involved in sugar binding at the non-reducing end of the central galactose of oligosaccharide ligands: sequence analysis, homology modeling and mutagenesis studies of hamster galectin-3
    • Henrick K, Bawumia S, Barboni EAM, Hughes RC. Evidence for subsites in the galectins involved in sugar binding at the non-reducing end of the central galactose of oligosaccharide ligands: sequence analysis, homology modeling and mutagenesis studies of hamster galectin-3. Glycobiology 1998;8:45-57.
    • (1998) Glycobiology , vol.8 , pp. 45-57
    • Henrick, K.1    Bawumia, S.2    Barboni, E.A.M.3    Hughes, R.C.4
  • 60
    • 0000594001 scopus 로고    scopus 로고
    • Role of the carboxyl-terminal domain in selfassociation of galectin-3
    • Yang RY, Hill PN, Hsu DK, Liu FT. Role of the carboxyl-terminal domain in selfassociation of galectin-3. Biochemistry 1998;37:4086-4092.
    • (1998) Biochemistry , vol.37 , pp. 4086-4092
    • Yang, R.Y.1    Hill, P.N.2    Hsu, D.K.3    Liu, F.T.4
  • 61
    • 0033566695 scopus 로고    scopus 로고
    • Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells
    • Kim HRC, Lin HM, Biliran H, Raz A. Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells. Cancer Res 1999;59:4148-4154.
    • (1999) Cancer Res , vol.59 , pp. 4148-4154
    • Kim, H.R.C.1    Lin, H.M.2    Biliran, H.3    Raz, A.4
  • 62
    • 33846026768 scopus 로고    scopus 로고
    • Importin-mediated nuclear translocation of galectin-3
    • Nakahara S, Hogan V, Inohara H, Raz A. Importin-mediated nuclear translocation of galectin-3. J Biol Chem 2006;281:39649-39659.
    • (2006) J Biol Chem , vol.281 , pp. 39649-39659
    • Nakahara, S.1    Hogan, V.2    Inohara, H.3    Raz, A.4
  • 64
    • 16844365210 scopus 로고    scopus 로고
    • Bile acids induce MUC2 overexpression in human colon carcinoma cells
    • Song S, Byrd JC, Koo JS, Bresalier RS. Bile acids induce MUC2 overexpression in human colon carcinoma cells. Cancer 2005;103:1606-1614.
    • (2005) Cancer , vol.103 , pp. 1606-1614
    • Song, S.1    Byrd, J.C.2    Koo, J.S.3    Bresalier, R.S.4
  • 65
    • 0032510596 scopus 로고    scopus 로고
    • Activation of NF-kappa-B via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosainduced mucin overproduction in epithelial cells
    • Li JD, Feng WJ, Gallup MG, Gum J, Kim Y, Basbaum C. Activation of NF-kappa-B via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosainduced mucin overproduction in epithelial cells. Proc Natl Acad Sci USA 1998;95: 5718-5723.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5718-5723
    • Li, J.D.1    Feng, W.J.2    Gallup, M.G.3    Gum, J.4    Kim, Y.5    Basbaum, C.6
  • 66
    • 0037160093 scopus 로고    scopus 로고
    • Transforming growth factor-beta-Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription
    • Jono H, Shuto T, Xu H, Kai H, Lim DJ, Gum JR, Kim JS, Yamaoka S, Feng XH, Li JD. Transforming growth factor-beta-Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription. J Biol Chem 2002;277:45547-45557.
    • (2002) J Biol Chem , vol.277 , pp. 45547-45557
    • Jono, H.1    Shuto, T.2    Xu, H.3    Kai, H.4    Lim, D.J.5    Gum, J.R.6    Kim, J.S.7    Yamaoka, S.8    Feng, X.H.9    Li, J.D.10
  • 67
    • 0035863509 scopus 로고    scopus 로고
    • The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters
    • Aslam F, Palumbo L, Augenlicht LH, Velcich A. The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters. Cancer Res 2001;61: 570-576.
    • (2001) Cancer Res , vol.61 , pp. 570-576
    • Aslam, F.1    Palumbo, L.2    Augenlicht, L.H.3    Velcich, A.4
  • 68
    • 0037199957 scopus 로고    scopus 로고
    • Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1
    • Perrais M, Pigny P, Copin MC, Aubert JP, Van Seuningen I. Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1. J Biol Chem 2002;277:32258-32267.
    • (2002) J Biol Chem , vol.277 , pp. 32258-32267
    • Perrais, M.1    Pigny, P.2    Copin, M.C.3    Aubert, J.P.4    Van Seuningen, I.5
  • 69
    • 0037462878 scopus 로고    scopus 로고
    • Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression
    • Yamamoto H, Bai YQ, Yuasa Y. Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression. Biochem Biophys Res Commun 2003;300:813-818.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 813-818
    • Yamamoto, H.1    Bai, Y.Q.2    Yuasa, Y.3
  • 70
    • 1542343886 scopus 로고    scopus 로고
    • Understanding the biochemical activities of galectin-1 and galectin-3 in the nucleus
    • Patterson RJ,WangW,Wang JL. Understanding the biochemical activities of galectin-1 and galectin-3 in the nucleus. Glycoconj J 2004;19:499-506.
    • (2004) Glycoconj J , vol.19 , pp. 499-506
    • Patterson, R.J.1    Wang, W.2    Wang, J.L.3
  • 72
    • 24744455701 scopus 로고    scopus 로고
    • Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis by activating Akt in human bladder carcinoma cells
    • Oka N, Nakahara S, Takenaka Y, Fukumori T, Hogan V, Kanayama HO, Yanagawa T, Raz A. Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis by activating Akt in human bladder carcinoma cells. Cancer Res 2005;65:7546-7553.
    • (2005) Cancer Res , vol.65 , pp. 7546-7553
    • Oka, N.1    Nakahara, S.2    Takenaka, Y.3    Fukumori, T.4    Hogan, V.5    Kanayama, H.O.6    Yanagawa, T.7    Raz, A.8
  • 74
    • 0030707480 scopus 로고    scopus 로고
    • Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
    • Akahani S, Nangia-Makker P, Inohara H, Kim HR, Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res 1997;57:5272-5276.
    • (1997) Cancer Res , vol.57 , pp. 5272-5276
    • Akahani, S.1    Nangia-Makker, P.2    Inohara, H.3    Kim, H.R.4    Raz, A.5
  • 75
    • 11144237933 scopus 로고    scopus 로고
    • Inhibition of N-(4-hydroxyphenyl)retinamideinduced apoptosis in breast cancer cells by galectin-3
    • Choi JH, Chun KH, Raz A, Lotan R. Inhibition of N-(4-hydroxyphenyl)retinamideinduced apoptosis in breast cancer cells by galectin-3. Cancer Biol Ther 2004;3:447-452.
    • (2004) Cancer Biol Ther , vol.3 , pp. 447-452
    • Choi, J.H.1    Chun, K.H.2    Raz, A.3    Lotan, R.4
  • 76
    • 0036510564 scopus 로고    scopus 로고
    • Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest
    • Yoshii T, Fukumori T, Honjo Y, Inohara H, Kim HR, Raz A. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. J Biol Chem 2002;277:6852-6857.
    • (2002) J Biol Chem , vol.277 , pp. 6852-6857
    • Yoshii, T.1    Fukumori, T.2    Honjo, Y.3    Inohara, H.4    Kim, H.R.5    Raz, A.6
  • 78
    • 0027936362 scopus 로고
    • Identification of human cellular and secreted ligands for galectin-3
    • Inohara H, Raz A. Identification of human cellular and secreted ligands for galectin-3. Biochem Biophys Res Commun 1994;201:1366-1375.
    • (1994) Biochem Biophys Res Commun , vol.201 , pp. 1366-1375
    • Inohara, H.1    Raz, A.2
  • 79
    • 0029027525 scopus 로고
    • Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells
    • Ohhannesian DW, Lotan D, Thomas P, Jessup JM, Fukuda M, Gabius HG, Lotan R. Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells. Cancer Res 1995;55:2191-2199.
    • (1995) Cancer Res , vol.55 , pp. 2191-2199
    • Ohhannesian, D.W.1    Lotan, D.2    Thomas, P.3    Jessup, J.M.4    Fukuda, M.5    Gabius, H.G.6    Lotan, R.7
  • 80
    • 0027229657 scopus 로고    scopus 로고
    • Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain
    • Koths K, Taylor E, Halenbeck R, Casipit C, Wang A. Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain. J Biol Chem 2003;268: 14245-14249.
    • (2003) J Biol Chem , vol.268 , pp. 14245-14249
    • Koths, K.1    Taylor, E.2    Halenbeck, R.3    Casipit, C.4    Wang, A.5
  • 81
    • 0035445710 scopus 로고    scopus 로고
    • Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
    • Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ. Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. Nucleic Acids Res 2001;27:3595-3602.
    • (2001) Nucleic Acids Res , vol.27 , pp. 3595-3602
    • Park, J.W.1    Voss, P.G.2    Grabski, S.3    Wang, J.L.4    Patterson, R.J.5
  • 82
    • 0034638829 scopus 로고    scopus 로고
    • Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin-3
    • Hikita C, Vijayakumar S, Takit J, Erdjument-Bromage H, Tempst P, Al-Awqati Q. Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin-3. J Cell Biol 2000;151:1235-1246.
    • (2000) J Cell Biol , vol.151 , pp. 1235-1246
    • Hikita, C.1    Vijayakumar, S.2    Takit, J.3    Erdjument-Bromage, H.4    Tempst, P.5    Al-Awqati, Q.6
  • 83
    • 0026601921 scopus 로고
    • Surface expression of functional IgE binding protein, an endogenous lectin, on mast cells and macrophages
    • Frigeri LG, Liu FT. Surface expression of functional IgE binding protein, an endogenous lectin, on mast cells and macrophages. J Immunol 1992;148:861-867.
    • (1992) J Immunol , vol.148 , pp. 861-867
    • Frigeri, L.G.1    Liu, F.T.2
  • 86
    • 0031885334 scopus 로고    scopus 로고
    • Evidence for subsites in the galectins involved in sugar binding at the nonreducing end of the central galactose of oligosaccharide ligands: sequence analysis, homology modeling and mutagenesis studies of hamster galectin-3
    • Henrick K, Bawumia S, Barboni EAM, Mehul B, Hughes RC. Evidence for subsites in the galectins involved in sugar binding at the nonreducing end of the central galactose of oligosaccharide ligands: sequence analysis, homology modeling and mutagenesis studies of hamster galectin-3. Glycobiology 1998;8:45-47.
    • (1998) Glycobiology , vol.8 , pp. 45-47
    • Henrick, K.1    Bawumia, S.2    Barboni, E.A.M.3    Mehul, B.4    Hughes, R.C.5
  • 87
    • 0036262673 scopus 로고    scopus 로고
    • High-affinity binding of recombinant human galectin-4 to SO3-3Gal-GalNAc pyranoside
    • Ideo H, Seko A, Ohkura T, Matta KL, Yamashita K. High-affinity binding of recombinant human galectin-4 to SO3-3Gal-GalNAc pyranoside. Glycobiology 2002;12:199-208.
    • (2002) Glycobiology , vol.12 , pp. 199-208
    • Ideo, H.1    Seko, A.2    Ohkura, T.3    Matta, K.L.4    Yamashita, K.5
  • 88
    • 0030750226 scopus 로고    scopus 로고
    • Novel GalNAc containing glycans on cytokeratins are recognized in vitro by galectins with type II carbohydrate recognition domains
    • Goletz S, Hanisch FG, Karsten U. Novel GalNAc containing glycans on cytokeratins are recognized in vitro by galectins with type II carbohydrate recognition domains. J Cell Sci 1997;110:1585-1596.
    • (1997) J Cell Sci , vol.110 , pp. 1585-1596
    • Goletz, S.1    Hanisch, F.G.2    Karsten, U.3
  • 89
    • 20344384247 scopus 로고    scopus 로고
    • Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs
    • Glinskii OV, Huxley VH, Glinsky GV, Pienta KJ, Raz A, Glinsky VV. Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. Neoplasia 2005;7:522-527.
    • (2005) Neoplasia , vol.7 , pp. 522-527
    • Glinskii, O.V.1    Huxley, V.H.2    Glinsky, G.V.3    Pienta, K.J.4    Raz, A.5    Glinsky, V.V.6
  • 90
    • 0026581048 scopus 로고
    • Modulation of the lung colonization of B16-F1 melanoma cells by citrus pectin
    • Platt D, Raz A. Modulation of the lung colonization of B16-F1 melanoma cells by citrus pectin. J Natl Cancer Inst 1992;84:438-442.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 438-442
    • Platt, D.1    Raz, A.2
  • 91
    • 0028608812 scopus 로고
    • Effects of natural complex carbohydrate (citrus pectin) on murine melanoma cell properties related to galectin-3 functions
    • Inohara H, Raz A. Effects of natural complex carbohydrate (citrus pectin) on murine melanoma cell properties related to galectin-3 functions. Glycoconj J 1994;11:527-532.
    • (1994) Glycoconj J , vol.11 , pp. 527-532
    • Inohara, H.1    Raz, A.2
  • 92
    • 0029900083 scopus 로고    scopus 로고
    • Expression of galectin-3 modulates T-cell growth and apoptosis
    • Yang RY, Hsu DK, Liu FT. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc Natl Acad Sci USA 1996;93:6737-6742.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6737-6742
    • Yang, R.Y.1    Hsu, D.K.2    Liu, F.T.3
  • 93
    • 0030707480 scopus 로고    scopus 로고
    • Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
    • Akahani S, Nangia-Makker P, Inohara H, Kim HR, Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res 1997;57:5272-5276.
    • (1997) Cancer Res , vol.57 , pp. 5272-5276
    • Akahani, S.1    Nangia-Makker, P.2    Inohara, H.3    Kim, H.R.4    Raz, A.5
  • 95
    • 0034487992 scopus 로고    scopus 로고
    • Effects of daily oral administration of quercetin chalcone and modified citrus pectin
    • Hayashi A, Hayashi A, Gillen AC, Lott JR. Effects of daily oral administration of quercetin chalcone and modified citrus pectin. Altern Med Rev 2000;5:546-552.
    • (2000) Altern Med Rev , vol.5 , pp. 546-552
    • Hayashi, A.1    Hayashi, A.2    Gillen, A.C.3    Lott, J.R.4
  • 97
    • 33646581315 scopus 로고    scopus 로고
    • Toward a core nutraceutical program for cancer management
    • McCarty MF and Block KI. Toward a core nutraceutical program for cancer management. Integr Cancer Ther 2006;5:150-171.
    • (2006) Integr Cancer Ther , vol.5 , pp. 150-171
    • McCarty, M.F.1    Block, K.I.2
  • 98
    • 34848848768 scopus 로고    scopus 로고
    • Inhibition of galectin-3 mediated cellular interactions by pectic polysaccharides from dietary sources
    • Sathisha UV, Jayaram S, Nayaka MAH, Dharmesh SM. Inhibition of galectin-3 mediated cellular interactions by pectic polysaccharides from dietary sources. Glycoconj J 2007;24:497-507.
    • (2007) Glycoconj J , vol.24 , pp. 497-507
    • Sathisha, U.V.1    Jayaram, S.2    Nayaka, M.A.H.3    Dharmesh, S.M.4
  • 99
    • 33144454670 scopus 로고    scopus 로고
    • Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis
    • Rabinovich GA, Cumashi A, Bianco GA, Ciavardelli D, Iurisci I, D'Egidio M, Piccolo E, Tinari N, Nifantiev N, Iacobelli S. Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis. Glycobiology 2006;16:210-220.
    • (2006) Glycobiology , vol.16 , pp. 210-220
    • Rabinovich, G.A.1    Cumashi, A.2    Bianco, G.A.3    Ciavardelli, D.4    Iurisci, I.5    D'Egidio, M.6    Piccolo, E.7    Tinari, N.8    Nifantiev, N.9    Iacobelli, S.10
  • 100
    • 13844256109 scopus 로고    scopus 로고
    • Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
    • Zou J, Glinsky VV, Landon LA, Matthews L, Deutscher SL. Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion. Carcinogenesis 2005;26:309-318.
    • (2005) Carcinogenesis , vol.26 , pp. 309-318
    • Zou, J.1    Glinsky, V.V.2    Landon, L.A.3    Matthews, L.4    Deutscher, S.L.5
  • 101
    • 33846241804 scopus 로고    scopus 로고
    • Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries
    • André S, Maljaars CE, Halkes KM, Gabius HJ, Kamerling JP. Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries. Bioorg Med Chem Lett 2007;17:793-798.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 793-798
    • André, S.1    Maljaars, C.E.2    Halkes, K.M.3    Gabius, H.J.4    Kamerling, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.