Evidence for subsites in the galectins involved in sugar binding at the nonreducing end of the central galactose of oligosaccharide ligands: Sequence analysis, homology modeling and mutagenesis studies of hamster galectin-3

Glycobiology

Volumn 8, Issue 1, 1998, Pages 45-57

  Henrick, Kim ^a,b   Bawumia, Sulemana ^a   Barboni, Erminia A M ^a,c   Mehul, Bruno ^a,d   Hughes, R Colin ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Institute for Cancer Research   (France)

Author keywords

Galectins; Mutagenesis; Sugar binding sites

Indexed keywords

GALECTIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOHYDRATE ANALYSIS; HAMSTER; MODEL; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STEREOCHEMISTRY; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DIFFERENTIATION; BASE SEQUENCE; BINDING SITES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CATTLE; CRICETINAE; DNA PRIMERS; GALACTOSE; GALECTIN 3; HUMANS; LECTINS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGOSACCHARIDES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SIALIC ACIDS;

BOVINAE; CRICETINAE;

EID: 0031885334     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/8.1.45     Document Type: Article

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