메뉴 건너뛰기




Volumn 14, Issue 1, 2013, Pages

Galectin-3: Its role in asthma and potential as an anti-inflammatory target

Author keywords

Airway hyperresponsiveness; Airway remodeling; Galectin 3; Inflammation; Leukocyte

Indexed keywords

GALECTIN 3; ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; OVALBUMIN;

EID: 84889812679     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-136     Document Type: Review
Times cited : (64)

References (101)
  • 1
    • 0037136416 scopus 로고    scopus 로고
    • Galectinomics: finding themes in complexity
    • Cooper DN. Galectinomics: finding themes in complexity. Biochim Biophys Acta 2002, 1572:209-231.
    • (2002) Biochim Biophys Acta , vol.1572 , pp. 209-231
    • Cooper, D.N.1
  • 2
    • 0033052588 scopus 로고    scopus 로고
    • C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway
    • Vasta GR, Quesenberry M, Ahmed H, O'Leary N. C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway. Dev Comp Immunol 1999, 23:401-420.
    • (1999) Dev Comp Immunol , vol.23 , pp. 401-420
    • Vasta, G.R.1    Quesenberry, M.2    Ahmed, H.3    O'Leary, N.4
  • 3
    • 80555149784 scopus 로고    scopus 로고
    • Galectins as pattern recognition receptors: structure, function, and evolution
    • Vasta GR. Galectins as pattern recognition receptors: structure, function, and evolution. Adv Exp Med Biol 2012, 946:21-36.
    • (2012) Adv Exp Med Biol , vol.946 , pp. 21-36
    • Vasta, G.R.1
  • 6
    • 1542337781 scopus 로고    scopus 로고
    • Seeing strangers or announcing " danger" : galectin-3 in two models of innate immunity
    • Sato S, Nieminen J. Seeing strangers or announcing " danger" : galectin-3 in two models of innate immunity. Glycoconj J 2004, 19:583-591.
    • (2004) Glycoconj J , vol.19 , pp. 583-591
    • Sato, S.1    Nieminen, J.2
  • 7
    • 65649109738 scopus 로고    scopus 로고
    • Roles of galectins in infection
    • Vasta GR. Roles of galectins in infection. Nat Rev Microbiol 2009, 7:424-438.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 424-438
    • Vasta, G.R.1
  • 8
    • 0032852619 scopus 로고    scopus 로고
    • Galectins: an evolutionarily conserved family of animal lectins with multifunctional properties; a trip from the gene to clinical therapy
    • Rabinovich GA. Galectins: an evolutionarily conserved family of animal lectins with multifunctional properties; a trip from the gene to clinical therapy. Cell Death Differ 1999, 6:711-721.
    • (1999) Cell Death Differ , vol.6 , pp. 711-721
    • Rabinovich, G.A.1
  • 10
    • 0032875554 scopus 로고    scopus 로고
    • God must love galectins; he made so many of them
    • Cooper DN, Barondes SH. God must love galectins; he made so many of them. Glycobiology 1999, 9:979-984.
    • (1999) Glycobiology , vol.9 , pp. 979-984
    • Cooper, D.N.1    Barondes, S.H.2
  • 11
    • 0033777862 scopus 로고    scopus 로고
    • Galectins: a new family of regulators of inflammation
    • Liu FT. Galectins: a new family of regulators of inflammation. Clin Immunol 2000, 97:79-88.
    • (2000) Clin Immunol , vol.97 , pp. 79-88
    • Liu, F.T.1
  • 12
    • 70349853957 scopus 로고    scopus 로고
    • Galectins
    • La Jolla, California: Cold Spring Harbor NY: The Consortium of Glycobiology Editors, Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME
    • Cummings RD, Liu FT. Galectins. Essentials of Glycobiology 2009, La Jolla, California: Cold Spring Harbor NY: The Consortium of Glycobiology Editors, Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME.
    • (2009) Essentials of Glycobiology
    • Cummings, R.D.1    Liu, F.T.2
  • 13
    • 67349258025 scopus 로고    scopus 로고
    • Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation
    • Rabinovich GA, Toscano MA. Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat Rev Immunol 2009, 9:338-352.
    • (2009) Nat Rev Immunol , vol.9 , pp. 338-352
    • Rabinovich, G.A.1    Toscano, M.A.2
  • 14
    • 0020058758 scopus 로고
    • Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies
    • Ho MK, Springer TA. Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J Immunol 1982, 128:1221-1228.
    • (1982) J Immunol , vol.128 , pp. 1221-1228
    • Ho, M.K.1    Springer, T.A.2
  • 16
    • 0036816147 scopus 로고    scopus 로고
    • Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions
    • Brewer CF, Miceli MC, Baum LG. Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions. Curr Opin Struct Biol 2002, 12:616-623.
    • (2002) Curr Opin Struct Biol , vol.12 , pp. 616-623
    • Brewer, C.F.1    Miceli, M.C.2    Baum, L.G.3
  • 18
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu FT, Rabinovich GA. Galectins as modulators of tumour progression. Nat Rev Cancer 2005, 5:29-41.
    • (2005) Nat Rev Cancer , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 19
    • 4544295231 scopus 로고    scopus 로고
    • Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity
    • Elad-Sfadia G, Haklai R, Balan E, Kloog Y. Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. J Biol Chem 2004, 279:34922-34930.
    • (2004) J Biol Chem , vol.279 , pp. 34922-34930
    • Elad-Sfadia, G.1    Haklai, R.2    Balan, E.3    Kloog, Y.4
  • 20
    • 0034737710 scopus 로고    scopus 로고
    • Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner
    • Menon RP, Strom M, Hughes RC. Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner. FEBS Lett 2000, 470:227-231.
    • (2000) FEBS Lett , vol.470 , pp. 227-231
    • Menon, R.P.1    Strom, M.2    Hughes, R.C.3
  • 25
    • 62549134859 scopus 로고    scopus 로고
    • Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis
    • Saegusa J, Hsu DK, Chen HY, Yu L, Fermin A, Fung MA, Liu FT. Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol 2009, 174:922-931.
    • (2009) Am J Pathol , vol.174 , pp. 922-931
    • Saegusa, J.1    Hsu, D.K.2    Chen, H.Y.3    Yu, L.4    Fermin, A.5    Fung, M.A.6    Liu, F.T.7
  • 29
    • 80054689970 scopus 로고    scopus 로고
    • Elevated production of galectin-3 is correlated with juvenile idiopathic arthritis disease activity, severity, and progression
    • Ezzat MH, El-Gammasy TM, Shaheen KY, Osman AO. Elevated production of galectin-3 is correlated with juvenile idiopathic arthritis disease activity, severity, and progression. Int J Rheum Dis 2011, 14:345-352.
    • (2011) Int J Rheum Dis , vol.14 , pp. 345-352
    • Ezzat, M.H.1    El-Gammasy, T.M.2    Shaheen, K.Y.3    Osman, A.O.4
  • 30
    • 35448956586 scopus 로고    scopus 로고
    • Serum galectin-3 and galectin-3 binding protein levels in Behcet's disease and their association with disease activity
    • Lee YJ, Kang SW, Song JK, Park JJ, Bae YD, Lee EY, Lee EB, Song YW. Serum galectin-3 and galectin-3 binding protein levels in Behcet's disease and their association with disease activity. Clin Exp Rheumatol 2007, 25:S41-S45.
    • (2007) Clin Exp Rheumatol , vol.25
    • Lee, Y.J.1    Kang, S.W.2    Song, J.K.3    Park, J.J.4    Bae, Y.D.5    Lee, E.Y.6    Lee, E.B.7    Song, Y.W.8
  • 35
    • 0024288959 scopus 로고
    • IgE-binding protein. Subcellular location and gene expression in many murine tissues and cells
    • Gritzmacher CA, Robertson MW, Liu FT. IgE-binding protein. Subcellular location and gene expression in many murine tissues and cells. J Immunol 1988, 141:2801-2806.
    • (1988) J Immunol , vol.141 , pp. 2801-2806
    • Gritzmacher, C.A.1    Robertson, M.W.2    Liu, F.T.3
  • 40
    • 80054796332 scopus 로고    scopus 로고
    • Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3
    • Darrow AL, Shohet RV, Maresh JG. Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3. Physiol Genomics 2011, 43:1144-1152.
    • (2011) Physiol Genomics , vol.43 , pp. 1144-1152
    • Darrow, A.L.1    Shohet, R.V.2    Maresh, J.G.3
  • 41
    • 42149133147 scopus 로고    scopus 로고
    • Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniae
    • Nieminen J, St-Pierre C, Bhaumik P, Poirier F, Sato S. Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniae. J Immunol 2008, 180:2466-2473.
    • (2008) J Immunol , vol.180 , pp. 2466-2473
    • Nieminen, J.1    St-Pierre, C.2    Bhaumik, P.3    Poirier, F.4    Sato, S.5
  • 42
    • 70350140359 scopus 로고    scopus 로고
    • Upregulation of oxidative stress markers in human microvascular endothelial cells by complexes of serum albumin and digestion products of glycated casein
    • Deo P, Glenn JV, Powell LA, Stitt AW, Ames JM. Upregulation of oxidative stress markers in human microvascular endothelial cells by complexes of serum albumin and digestion products of glycated casein. J Biochem Mol Toxicol 2009, 23:364-372.
    • (2009) J Biochem Mol Toxicol , vol.23 , pp. 364-372
    • Deo, P.1    Glenn, J.V.2    Powell, L.A.3    Stitt, A.W.4    Ames, J.M.5
  • 43
    • 33646015980 scopus 로고    scopus 로고
    • Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3
    • Gil CD, La M, Perretti M, Oliani SM. Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3. Cell Biol Int 2006, 30:338-344.
    • (2006) Cell Biol Int , vol.30 , pp. 338-344
    • Gil, C.D.1    La, M.2    Perretti, M.3    Oliani, S.M.4
  • 44
    • 38849191822 scopus 로고    scopus 로고
    • Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow
    • Rao SP, Wang Z, Zuberi RI, Sikora L, Bahaie NS, Zuraw BL, Liu FT, Sriramarao P. Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol 2007, 179:7800-7807.
    • (2007) J Immunol , vol.179 , pp. 7800-7807
    • Rao, S.P.1    Wang, Z.2    Zuberi, R.I.3    Sikora, L.4    Bahaie, N.S.5    Zuraw, B.L.6    Liu, F.T.7    Sriramarao, P.8
  • 45
    • 0029900083 scopus 로고    scopus 로고
    • Expression of galectin-3 modulates T-cell growth and apoptosis
    • Yang RY, Hsu DK, Liu FT. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc Natl Acad Sci U S A 1996, 93:6737-6742.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 6737-6742
    • Yang, R.Y.1    Hsu, D.K.2    Liu, F.T.3
  • 48
    • 0034855758 scopus 로고    scopus 로고
    • Galectin-3 protects human breast carcinoma cells against nitric oxide-induced apoptosis: implication of galectin-3 function during metastasis
    • Moon BK, Lee YJ, Battle P, Jessup JM, Raz A, Kim HR. Galectin-3 protects human breast carcinoma cells against nitric oxide-induced apoptosis: implication of galectin-3 function during metastasis. Am J Pathol 2001, 159:1055-1060.
    • (2001) Am J Pathol , vol.159 , pp. 1055-1060
    • Moon, B.K.1    Lee, Y.J.2    Battle, P.3    Jessup, J.M.4    Raz, A.5    Kim, H.R.6
  • 49
    • 0037013214 scopus 로고    scopus 로고
    • Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation
    • Yu F, Finley RL, Raz A, Kim HR. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem 2002, 277:15819-15827.
    • (2002) J Biol Chem , vol.277 , pp. 15819-15827
    • Yu, F.1    Finley, R.L.2    Raz, A.3    Kim, H.R.4
  • 50
    • 0034685681 scopus 로고    scopus 로고
    • Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis
    • Matarrese P, Tinari N, Semeraro ML, Natoli C, Iacobelli S, Malorni W. Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett 2000, 473:311-315.
    • (2000) FEBS Lett , vol.473 , pp. 311-315
    • Matarrese, P.1    Tinari, N.2    Semeraro, M.L.3    Natoli, C.4    Iacobelli, S.5    Malorni, W.6
  • 53
    • 40049098522 scopus 로고    scopus 로고
    • CD66b regulates adhesion and activation of human eosinophils
    • Yoon J, Terada A, Kita H. CD66b regulates adhesion and activation of human eosinophils. J Immunol 2007, 179:8454-8462.
    • (2007) J Immunol , vol.179 , pp. 8454-8462
    • Yoon, J.1    Terada, A.2    Kita, H.3
  • 54
    • 0033870111 scopus 로고    scopus 로고
    • Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses
    • Hsu DK, Yang RY, Pan Z, Yu L, Salomon DR, Fung-Leung WP, Liu FT. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 2000, 156:1073-1083.
    • (2000) Am J Pathol , vol.156 , pp. 1073-1083
    • Hsu, D.K.1    Yang, R.Y.2    Pan, Z.3    Yu, L.4    Salomon, D.R.5    Fung-Leung, W.P.6    Liu, F.T.7
  • 55
    • 0031850611 scopus 로고    scopus 로고
    • Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice
    • Colnot C, Ripoche MA, Milon G, Montagutelli X, Crocker PR, Poirier F. Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice. Immunology 1998, 94:290-296.
    • (1998) Immunology , vol.94 , pp. 290-296
    • Colnot, C.1    Ripoche, M.A.2    Milon, G.3    Montagutelli, X.4    Crocker, P.R.5    Poirier, F.6
  • 56
    • 0028874589 scopus 로고
    • Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages
    • Liu FT, Hsu DK, Zuberi RI, Kuwabara I, Chi EY, Henderson WR. Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am J Pathol 1995, 147:1016-1028.
    • (1995) Am J Pathol , vol.147 , pp. 1016-1028
    • Liu, F.T.1    Hsu, D.K.2    Zuberi, R.I.3    Kuwabara, I.4    Chi, E.Y.5    Henderson, W.R.6
  • 59
    • 0037460123 scopus 로고    scopus 로고
    • Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro
    • Nair MG, Cochrane DW, Allen JE. Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro. Immunol Lett 2003, 85:173-180.
    • (2003) Immunol Lett , vol.85 , pp. 173-180
    • Nair, M.G.1    Cochrane, D.W.2    Allen, J.E.3
  • 60
    • 20044387192 scopus 로고    scopus 로고
    • Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
    • Raes G, Brys L, Dahal BK, Brandt J, Grooten J, Brombacher F, Vanham G, Noel W, Bogaert P, Boonefaes T, et al. Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol 2005, 77:321-327.
    • (2005) J Leukoc Biol , vol.77 , pp. 321-327
    • Raes, G.1    Brys, L.2    Dahal, B.K.3    Brandt, J.4    Grooten, J.5    Brombacher, F.6    Vanham, G.7    Noel, W.8    Bogaert, P.9    Boonefaes, T.10
  • 61
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T (H)1/T (H)2 paradigm
    • Wynn TA. Fibrotic disease and the T (H)1/T (H)2 paradigm. Nat Rev Immunol 2004, 4:583-594.
    • (2004) Nat Rev Immunol , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 65
    • 23944500772 scopus 로고    scopus 로고
    • C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions
    • Cumpstey I, Sundin A, Leffler H, Nilsson UJ. C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions. Angew Chem Int Ed Engl 2005, 44:5110-5112.
    • (2005) Angew Chem Int Ed Engl , vol.44 , pp. 5110-5112
    • Cumpstey, I.1    Sundin, A.2    Leffler, H.3    Nilsson, U.J.4
  • 66
    • 0029942555 scopus 로고    scopus 로고
    • Galectin-3 promotes adhesion of human neutrophils to laminin
    • Kuwabara I, Liu FT. Galectin-3 promotes adhesion of human neutrophils to laminin. J Immunol 1996, 156:3939-3944.
    • (1996) J Immunol , vol.156 , pp. 3939-3944
    • Kuwabara, I.1    Liu, F.T.2
  • 67
    • 0037083447 scopus 로고    scopus 로고
    • Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumonia
    • Sato S, Ouellet N, Pelletier I, Simard M, Rancourt A, Bergeron MG. Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumonia. J Immunol 2002, 168:1813-1822.
    • (2002) J Immunol , vol.168 , pp. 1813-1822
    • Sato, S.1    Ouellet, N.2    Pelletier, I.3    Simard, M.4    Rancourt, A.5    Bergeron, M.G.6
  • 68
    • 33748791467 scopus 로고    scopus 로고
    • Crosslinking of CD66B on peripheral blood neutrophils mediates the release of interleukin-8 from intracellular storage
    • Schroder AK, Uciechowski P, Fleischer D, Rink L. Crosslinking of CD66B on peripheral blood neutrophils mediates the release of interleukin-8 from intracellular storage. Hum Immunol 2006, 67:676-682.
    • (2006) Hum Immunol , vol.67 , pp. 676-682
    • Schroder, A.K.1    Uciechowski, P.2    Fleischer, D.3    Rink, L.4
  • 69
    • 0031949975 scopus 로고    scopus 로고
    • Embryonic implantation in galectin 1/galectin 3 double mutant mice
    • Colnot C, Fowlis D, Ripoche MA, Bouchaert I, Poirier F. Embryonic implantation in galectin 1/galectin 3 double mutant mice. Dev Dyn 1998, 211:306-313.
    • (1998) Dev Dyn , vol.211 , pp. 306-313
    • Colnot, C.1    Fowlis, D.2    Ripoche, M.A.3    Bouchaert, I.4    Poirier, F.5
  • 70
    • 0033571388 scopus 로고    scopus 로고
    • Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils
    • Feuk-Lagerstedt E, Jordan ET, Leffler H, Dahlgren C, Karlsson A. Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils. J Immunol 1999, 163:5592-5598.
    • (1999) J Immunol , vol.163 , pp. 5592-5598
    • Feuk-Lagerstedt, E.1    Jordan, E.T.2    Leffler, H.3    Dahlgren, C.4    Karlsson, A.5
  • 71
    • 33847718338 scopus 로고    scopus 로고
    • Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer
    • Nieminen J, Kuno A, Hirabayashi J, Sato S. Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer. J Biol Chem 2007, 282:1374-1383.
    • (2007) J Biol Chem , vol.282 , pp. 1374-1383
    • Nieminen, J.1    Kuno, A.2    Hirabayashi, J.3    Sato, S.4
  • 72
    • 0028951736 scopus 로고
    • A human lectin, galectin-3 (epsilon bp/Mac-2), stimulates superoxide production by neutrophils
    • Yamaoka A, Kuwabara I, Frigeri LG, Liu FT. A human lectin, galectin-3 (epsilon bp/Mac-2), stimulates superoxide production by neutrophils. J Immunol 1995, 154:3479-3487.
    • (1995) J Immunol , vol.154 , pp. 3479-3487
    • Yamaoka, A.1    Kuwabara, I.2    Frigeri, L.G.3    Liu, F.T.4
  • 73
    • 27644480032 scopus 로고    scopus 로고
    • Galectin-3 interacts with naive and primed neutrophils, inducing innate immune responses
    • Nieminen J, St-Pierre C, Sato S. Galectin-3 interacts with naive and primed neutrophils, inducing innate immune responses. J Leukoc Biol 2005, 78:1127-1135.
    • (2005) J Leukoc Biol , vol.78 , pp. 1127-1135
    • Nieminen, J.1    St-Pierre, C.2    Sato, S.3
  • 77
    • 79954985884 scopus 로고    scopus 로고
    • Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes
    • Lopez E, Zafra MP, Sastre B, Gamez C, Lahoz C, Del Pozo V. Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes. Mediators Inflamm 2011, 2011:823279.
    • (2011) Mediators Inflamm , vol.2011 , pp. 823279
    • Lopez, E.1    Zafra, M.P.2    Sastre, B.3    Gamez, C.4    Lahoz, C.5    Del Pozo, V.6
  • 78
    • 0027338013 scopus 로고
    • Epsilon BP, a beta-galactoside-binding animal lectin, recognizes IgE receptor (Fc epsilon RI) and activates mast cells
    • Frigeri LG, Zuberi RI, Liu FT. Epsilon BP, a beta-galactoside-binding animal lectin, recognizes IgE receptor (Fc epsilon RI) and activates mast cells. Biochemistry 1993, 32:7644-7649.
    • (1993) Biochemistry , vol.32 , pp. 7644-7649
    • Frigeri, L.G.1    Zuberi, R.I.2    Liu, F.T.3
  • 79
    • 0028237187 scopus 로고
    • Activation of rat basophilic leukemia cells by epsilon BP, an IgE-binding endogenous lectin
    • Zuberi RI, Frigeri LG, Liu FT. Activation of rat basophilic leukemia cells by epsilon BP, an IgE-binding endogenous lectin. Cell Immunol 1994, 156:1-12.
    • (1994) Cell Immunol , vol.156 , pp. 1-12
    • Zuberi, R.I.1    Frigeri, L.G.2    Liu, F.T.3
  • 80
    • 41949104907 scopus 로고    scopus 로고
    • Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition
    • Suzuki Y, Inoue T, Yoshimaru T, Ra C. Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition. Biochim Biophys Acta 2008, 1783:924-934.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 924-934
    • Suzuki, Y.1    Inoue, T.2    Yoshimaru, T.3    Ra, C.4
  • 81
    • 33749530044 scopus 로고    scopus 로고
    • Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression
    • Chen HY, Sharma BB, Yu L, Zuberi R, Weng IC, Kawakami Y, Kawakami T, Hsu DK, Liu FT. Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol 2006, 177:4991-4997.
    • (2006) J Immunol , vol.177 , pp. 4991-4997
    • Chen, H.Y.1    Sharma, B.B.2    Yu, L.3    Zuberi, R.4    Weng, I.C.5    Kawakami, Y.6    Kawakami, T.7    Hsu, D.K.8    Liu, F.T.9
  • 83
    • 30744445427 scopus 로고    scopus 로고
    • Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
    • Stillman BN, Hsu DK, Pang M, Brewer CF, Johnson P, Liu FT, Baum LG. Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol 2006, 176:778-789.
    • (2006) J Immunol , vol.176 , pp. 778-789
    • Stillman, B.N.1    Hsu, D.K.2    Pang, M.3    Brewer, C.F.4    Johnson, P.5    Liu, F.T.6    Baum, L.G.7
  • 84
    • 0036232707 scopus 로고    scopus 로고
    • Induction of cell death in T lymphocytes by invasin via beta1-integrin
    • Arencibia I, Frankel G, Sundqvist KG. Induction of cell death in T lymphocytes by invasin via beta1-integrin. Eur J Immunol 2002, 32:1129-1138.
    • (2002) Eur J Immunol , vol.32 , pp. 1129-1138
    • Arencibia, I.1    Frankel, G.2    Sundqvist, K.G.3
  • 85
    • 0029959827 scopus 로고    scopus 로고
    • Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells
    • Brown TJ, Shuford WW, Wang WC, Nadler SG, Bailey TS, Marquardt H, Mittler RS. Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells. J Biol Chem 1996, 271:27686-27695.
    • (1996) J Biol Chem , vol.271 , pp. 27686-27695
    • Brown, T.J.1    Shuford, W.W.2    Wang, W.C.3    Nadler, S.G.4    Bailey, T.S.5    Marquardt, H.6    Mittler, R.S.7
  • 86
    • 0031573142 scopus 로고    scopus 로고
    • CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway
    • Lesage S, Steff AM, Philippoussis F, Page M, Trop S, Mateo V, Hugo P. CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway. J Immunol 1997, 159:4762-4771.
    • (1997) J Immunol , vol.159 , pp. 4762-4771
    • Lesage, S.1    Steff, A.M.2    Philippoussis, F.3    Page, M.4    Trop, S.5    Mateo, V.6    Hugo, P.7
  • 88
    • 0036678172 scopus 로고    scopus 로고
    • An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells
    • Ng PP, Dela Cruz JS, Sorour DN, Stinebaugh JM, Shin SU, Shin DS, Morrison SL, Penichet ML. An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells. Proc Natl Acad Sci U S A 2002, 99:10706-10711.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10706-10711
    • Ng, P.P.1    Dela Cruz, J.S.2    Sorour, D.N.3    Stinebaugh, J.M.4    Shin, S.U.5    Shin, D.S.6    Morrison, S.L.7    Penichet, M.L.8
  • 89
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999, 17:255-281.
    • (1999) Annu Rev Immunol , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 91
    • 33645101537 scopus 로고    scopus 로고
    • Inflammatory subtypes in asthma: assessment and identification using induced sputum
    • Simpson JL, Scott R, Boyle MJ, Gibson PG. Inflammatory subtypes in asthma: assessment and identification using induced sputum. Respirology 2006, 11:54-61.
    • (2006) Respirology , vol.11 , pp. 54-61
    • Simpson, J.L.1    Scott, R.2    Boyle, M.J.3    Gibson, P.G.4
  • 98
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 2008, 8:183-192.
    • (2008) Nat Rev Immunol , vol.8 , pp. 183-192
    • Barnes, P.J.1
  • 101


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.