The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK

Frontiers in Pharmacology

Volumn 4 NOV, Issue , 2013, Pages

  Beltrán, Leopoldo R ^a   Dawid, Corinna ^b   Beltrán, Madeline ^a   Gisselmann, Guenter ^a   Degenhardt, Katharina ^b   Mathie, Klaus ^b   Hofmann, Thomas ^b   Hatt, Hanns ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

6 gingerol; Capsaicin; K2p channels; Piperine; Polygodial; Pungency

Indexed keywords

(6) GINGEROL; CAPSAICIN; PIPERINE; POLYGODIAL; POTASSIUM CHANNEL; PROTEIN TASK 1; PROTEIN TASK 3; PROTEIN TRESK; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRODE; HUMAN; IC 50; INHIBITION KINETICS; MOLECULAR BIOLOGY; MUTANT; NONHUMAN; OOCYTE; VOLTAGE CLAMP TECHNIQUE; WILD TYPE; XENOPUS LAEVIS;

EID: 84889678646     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00141     Document Type: Article

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