Could capsaicinoids help to support weight management? A systematic review and meta-analysis of energy intake data

Appetite

Volumn 73, Issue , 2014, Pages 183-188

  Whiting, S ^a   Derbyshire, E J ^a   Tiwari, B ^b  

^a School of Healthcare Science   (United Kingdom)

^b TEAGASC FOOD RESEARCH CENTRE   (Ireland)

Author keywords

Capsaicin; Capsaicinoids; Chili; Chilli; Energy intake; Weight management

Indexed keywords

ALKALOID; CAPSAICIN; CAPSAICINOIDS; CARBOHYDRATE; CATECHOLAMINE; SIBUTRAMINE; UNCLASSIFIED DRUG;

ADRENERGIC SYSTEM; APPETITE; BODY MASS; BROWN ADIPOSE TISSUE; CALORIC INTAKE; DATA BASE; EFFECT SIZE; ENERGY BALANCE; ENERGY EXPENDITURE; ETHNIC AND RACIAL GROUPS; ETHNICITY; EVIDENCE BASED PRACTICE; EXERCISE; FAT CONTENT; FOOD INTAKE; HORMONE DETERMINATION; HUMAN; HUNGER; LIPID OXIDATION; MEAL; MEDLINE; META ANALYSIS; ORBITAL CORTEX; PEPPER; PHYSICAL ACTIVITY; REVIEW; SATIETY; SENSATION; SYSTEMATIC REVIEW; WEIGHT CONTROL; WEIGHT REDUCTION;

CAPSAICIN; CAPSAICINOIDS; CHILI; CHILLI; ENERGY INTAKE; WEIGHT MANAGEMENT;

CAPSAICIN; CAPSICUM; ENERGY INTAKE; FOOD PREFERENCES; HUMANS; OBESITY; PHYTOTHERAPY; PLANT EXTRACTS; WEIGHT LOSS;

EID: 84889654600     PISSN: 01956663     EISSN: 10958304     Source Type: Journal    
DOI: 10.1016/j.appet.2013.11.005     Document Type: Review

References (45)

1. Adan R.A.H., Vanderschuren L.J.M.J., E la Fleur S. Anti-obesity drugs and neural circuits of feeding. Trends in Pharmacological Sciences 2008, 29(4):208-217.
2. Ahuja K.D., Robertson I.K., Geraghty D.P., Ball M.J. The effect of 4-week chilli supplementation on metabolic and arterial function in humans. European Journal of Clinical Nutrition 2007, 61(3):326-333.
3. Bax L., Yu L.M., Ikeda N., Tsuruta H., Moons K.G. Development and validation of MIX. Comprehensive free software for meta-analysis of causal research data. BMC Medical Research Methodology 2006, 6:50.
4. Belza A., Frandsen E., Kondrup J. Body fat loss achieved by stimulation of thermogenesis by a combination of bioactive food ingredients. A placebo-controlled, double-blind 8-week intervention in obese subjects. International Journal of Obesity 2007, 31(1):121-130.
5. Borenstein M. Introduction to meta-analysis 2009, John Wiley & Sons, Chichester, U.K.
6. Castañeda T.R., Tong J., Datta R., Culler M., Tschöp M.H. Ghrelin in the regulation of body weight and metabolism. Frontiers in Neuroendocrinology 2010, 31(1):44-60.
7. Choi S.E., Kim T.H., Yi S.A., Hwang Y.C., Hwang W.S., Choe S.J., et al. Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. Nutrition Research 2011, 31(6):468-478.
8. Clapham J.C., Arch J.R.S., Tadayyon M. Anti-obesity drugs. A critical review of current therapies and future opportunities. Pharmacology & Therapeutics 2001, 89(1):81-121.
9. Galgani J.E., Ravussin E. Effect of dihydrocapsiate on resting metabolic rate in humans. The American Journal of Clinical Nutrition 2010, 92(5):1089-1093.
10. Gonlachanvit S. Are rice and spicy diet good for functional gastrointestinal disorders?. Journal of Neurogastroenterology and Motility 2010, 16(2):131-138.
11. Gunthorpe M.J., Szallasi A. Peripheral TRPV1 receptors as targets for drug development. New molecules and mechanisms. Current Pharmaceutical Design 2008, 14(1):32-41.
12. Henning S.M., Zhang Y., Seeram N.P., Lee R.P., Wang P., Bowerman S., et al. Antioxidant capacity and phytochemical content of herbs and spices in dry, fresh and blended herb paste form. International Journal of Food Sciences and Nutrition 2011, 62(3):219-225.
13. Higgins J.P., Thompson S.G., Deeks J.J., Altman D.G. Measuring inconsistency in meta-analyses. BMJ 2003, 327(7414):557-560.
14. Hill J.O. Understanding and addressing the epidemic of obesity. An energy balance perspective. Endocrine Reviews 2006, 27(7):750-761.
15. Holst J.J. The physiology of glucagon-like peptide 1. Physiological Reviews 2007, 87(4):1409-1439.
16. Horner K.M., Byrne N.M., Cleghorn G.J., Naslund E., King N.A. The effects of weight loss strategies on gastric emptying and appetite control. Obesity Reviews. An Official Journal of the International Association for the Study of Obesity 2011, 12(11):935-951.
17. Hursel R., Westerterp-Plantenga M.S. Thermogenic ingredients and body weight regulation. International Journal of Obesity 2010, 34(4):659-669.
18. Josse A.R., Sherriffs S.S., Holwerda A.M., Andrews R., Staples A.W., Phillips S.M. Effects of capsinoid ingestion on energy expenditure and lipid oxidation at rest and during exercise. Nutrition & Metabolism 2010, 7:65.
19. Kadohisa M., Rolls E.T., Verhagen J.V. Orbitofrontal cortex. Neuronal representation of oral temperature and capsaicin in addition to taste and texture. Neuroscience 2004, 127(1):207-221.
20. Kwon K.-T., Uddin M.S., Jung G.-W., Sim J.-E., Lee S.-M., Woo H.-C., et al. Solubility of red pepper (Capsicum annum) oil in near- and supercritical carbon dioxide and quantification of capsaicin. Korean Journal of Chemical Engineering 2011, 28(6):1433-1438.
21. Lee T.A., Li Z., Zerlin A., Heber D. Effects of dihydrocapsiate on adaptive and diet-induced thermogenesis with a high protein very low calorie diet. A randomized control trial. Nutrition & Metabolism 2010, 7:78.
22. Lejeune M.P., Kovacs E.M., Westerterp-Plantenga M.S. Effect of capsaicin on substrate oxidation and weight maintenance after modest body-weight loss in human subjects. The British Journal of Nutrition 2003, 90(3):651-659.
23. Ludy M.-J., Mattes R.D. The effects of hedonically acceptable red pepper doses on thermogenesis and appetite. Physiology & Behavior 2011, 102(3-4):251-258.
24. Ludy M.-J., Moore G.E., Mattes R.D. The effects of capsaicin and capsiate on energy balance. Critical review and meta-analyses of studies in humans. Chemical Senses 2012, 37(2):103-121.
25. Luo X.J., Peng J., Li Y.J. Recent advances in the study on capsaicinoids and capsinoids. European Journal of Pharmacology 2011, 650(1):1-7.
26. McGavigan A.K., Murphy K.G. Gut hormones. The future of obesity treatment?. British Journal of Clinical Pharmacology 2012, 74(6):911-919.
27. Meghvansi M.K., Siddiqui S., Khan M.H., Gupta V.K., Vairale M.G., Gogoi H.K., et al. Naga chilli. A potential source of capsaicinoids with broad-spectrum ethnopharmacological applications. Journal of Ethnopharmacology 2010, 132(1):1-14.
28. Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses. The PRISMA statement. International Journal of Surgery 2010, 8(5):336-341.
29. Reinbach H.C., Martinussen T., Moller P. Effects of hot spices on energy intake, appetite and sensory specific desires in humans. Food Quality and Preference 2010, 21(6):655-661.
30. Reinbach H.C., Smeets A., Martinussen T., Moller P., Westerterp-Plantenga M.S. Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance. Clinical Nutrition 2009, 28(3):260-265.
31. Rolls E.T. The functions of the orbitofrontal cortex. Brain and Cognition 2004, 55(1):11-29.
32. Rolls E.T. Smell, taste, texture, and temperature multimodal representations in the brain, and their relevance to the control of appetite. Nutrition Reviews 2004, 62(11 Pt 2):S193-204. discussion S224-141.
33. Sanatombi K., Sharma G.J. Capsaicin content and pungency of different capsicum spp. Cultivars. Notulae Botanicae Horti Agrobotanici Cluj-Napoca 2008, 36(2):89-90.
34. Smeets A., Westerterp-Plantenga M. The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. European Journal of Nutrition 2009, 48(4):229-234.
35. Snitker S., Fujishima Y., Shen H., Ott S., Pi-Sunyer X., Furuhata Y., et al. Effects of novel capsinoid treatment on fatness and energy metabolism in humans. Possible pharmacogenetic implications. The American Journal of Clinical Nutrition 2009, 89(1):45-50.
36. Stern L., Iqbal N., Seshadri P., Chicano K.L., Daily D.A., McGrory J., et al. The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults. One-year follow-up of a randomized trial. Annals of Internal Medicine 2004, 140(10):778-785.
37. Szallasi A., Cruz F., Geppetti P. TRPV1. A therapeutic target for novel analgesic drugs?. Trends in Molecular Medicine 2006, 12(11):545-554.
38. Tominaga M., Tominaga T. Structure and function of TRPV1. Pflugers Archiv. European Journal of Physiology 2005, 451(1):143-150.
39. Westerterp-Plantenga M.S., Smeets A., Lejeune M.P. Sensory and gastrointestinal satiety effects of capsaicin on food intake. International Journal of Obesity 2005, 29(6):682-688.
40. Whiting S., Derbyshire E., Tiwari B.K. Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite 2012, 59(2):341-348.
41. Yang Z.-H., Wang X.-H., Wang H.-P., Hu L.-Q., Zheng X.-M., Li S.-W. Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization. Urology 2010, 75(3):735-741.
42. Yoneshiro T., Aita S., Kawai Y., Iwanaga T., Saito M. Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans. The American Journal of Clinical Nutrition 2012, 95(4):845-850.
43. Yoshioka M., Imanaga M., Ueyama H., Yamane M., Kubo Y., Boivin A., et al. Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth. The British Journal of Nutrition 2004, 91(6):991-995.
44. Yoshioka M., Lim K., Kikuzato S., Kiyonaga A., Tanaka H., Shindo M., et al. Effects of red-pepper diet on the energy metabolism in men. Journal of Nutritional Science and Vitaminology 1995, 41(6):647-656.
45. Yoshioka M., St-Pierre S., Drapeau V., Dionne I., Doucet E., Suzuki M., et al. Effects of red pepper on appetite and energy intake. The British Journal of Nutrition 1999, 82(2):115-123.