메뉴 건너뛰기




Volumn 5, Issue 22, 2013, Pages 2803-2820

The challenges of LC-MS/MS analysis of opiates and opioids in urine

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYLIDENE 1,5 DIMETHYL 3,3 DIPHENYLPYRROLIDINE; BUPRENORPHINE; BUPRENORPHINE 3 GLUCURONIDE; BUPRENORPHINE PLUS NALOXONE; CODEINE; DIAMORPHINE; DIHYDROCODEINE; DIHYDROMORPHINE; ENDORPHIN; FENTANYL; HYDROCODONE; HYDROMORPHONE; METHADONE; MORPHINE; MORPHINE 6 ACETATE; NALOXONE; NALOXONE 3 GLUCURONIDE; NARCOTIC ANALGESIC AGENT; NORBUPRENORPHINE; NORBUPRENORPHINE 3 GLUCURONIDE; NORCODEINE; NORFENTANYL; NOROXYCODONE; NOROXYMORPHONE; OPIATE; OXYCODONE; OXYMORPHONE; OXYMORPHONE 3 GLUCURONIDE; PETHIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84889569083     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.244     Document Type: Review
Times cited : (23)

References (79)
  • 1
    • 0029852678 scopus 로고    scopus 로고
    • Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the μ-opioid receptor gene
    • Matthes HW, Maldonado R, Simonin F et al. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the μ-opioid receptor gene. Nature 383, 819-823 (1996
    • (1996) Nature , vol.383 , pp. 819-823
    • Matthes, H.W.1    Maldonado, R.2    Simonin, F.3
  • 3
    • 44649093947 scopus 로고    scopus 로고
    • Opioids and the control of respiration
    • DOI 10.1093/bja/aen094
    • Pattinson KT. Opioids and the control of respiration. Br. J. Anaesth. 100(6), 747-758 (2008 (Pubitemid 351774332)
    • (2008) British Journal of Anaesthesia , vol.100 , Issue.6 , pp. 747-758
    • Pattinson, K.T.S.1
  • 4
    • 0022546230 scopus 로고
    • Inhibition of gastrointestinal transit by morphine in rats results primarily from direct drug action on gut opioid sites
    • Manara L, Bianchi G, Ferretti P, Tavani A. Inhibition of gastrointestinal transit by morphine in rats results from direct drug action on gut opioid sites. J. Pharmacol. Exp. Ther. 237(3), 945-949 (1986 (Pubitemid 16088118)
    • (1986) Journal of Pharmacology and Experimental Therapeutics , vol.237 , Issue.3 , pp. 945-949
    • Manara, L.1    Bianchi, G.2    Ferretti, P.3    Tavani, A.4
  • 6
    • 84863649956 scopus 로고    scopus 로고
    • Management of opioid analgesic overdose
    • Boyer EW. Management of opioid analgesic overdose. N. Engl. J. Med. 367(2), 146-155 (2012
    • (2012) N. Engl. J. Med , vol.367 , Issue.2 , pp. 146-155
    • Boyer, E.W.1
  • 8
    • 43649101761 scopus 로고    scopus 로고
    • Therapeutic opioids: A ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids
    • Opioids
    • Manchikanti L, Singh A. Therapeutic opioids: A ten-year perspective on the complexities and complications of the escalating use, abuse and non-medical use of opioids. Pain Physician 11, S63-S88 (2008 (Pubitemid 351682079)
    • (2008) Pain Physician , vol.11 , Issue.SPEC. ISSUE. 2
    • Manchikanti, L.1    Singh, A.2
  • 9
    • 84871890217 scopus 로고    scopus 로고
    • 2011 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 29th annual report
    • Bronstein AC, Spyker DA, Cantilena LR Jr, Rumack BH, Dart RC. 2011 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 29th annual report. Clin. Toxicol. Phila) 50(10), 911-1164 (2012
    • (2012) Clin. Toxicol. Phila , vol.50 , Issue.10 , pp. 911-1164
    • Bronstein, A.C.1    Spyker, D.A.2    Cantilena Jr., L.R.3    Rumack, B.H.4    Dart, R.C.5
  • 10
    • 45549108542 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs
    • Cunha-Oliveira T, Rego AC, Oliveira CR. Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs. Brain Res. Rev. 58, 192-208 (2008
    • (2008) Brain Res. Rev , vol.58 , pp. 192-208
    • Cunha-Oliveira, T.1    Rego, A.C.2    Oliveira, C.R.3
  • 11
    • 38049086787 scopus 로고    scopus 로고
    • Association of personality disorders, family conflicts and treatment with quality of life in opiate addiction
    • Karow A, Verthein U, Krausz M, Schäfer I. Association of personality disorders, family conflicts and treatment with quality of life in opiate addiction. Eur. Addict. Res. 14, 38-46 (2008
    • (2008) Eur. Addict. Res , vol.14 , pp. 38-46
    • Karow, A.1    Verthein, U.2    Krausz, M.3    Schäfer, I.4
  • 12
    • 33751574267 scopus 로고    scopus 로고
    • Neurorobiology and evidence-based biological treatments for substance abuse disorders
    • Ivanov IS, Schulz, KP, Palmero RC, Newcorn JH. Neurobiology and evidence-based biological treatments for substance abuse disorders. CNS Spectr. 11(11), 864-877 (2006 (Pubitemid 44845664)
    • (2006) CNS Spectrums , vol.11 , Issue.11 , pp. 864-877
    • Ivanov, I.S.1    Schulz, K.P.2    Palmero, R.C.3    Newcorn, J.H.4
  • 14
    • 33645509739 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature
    • Rook EJ, Huitema ADR, van den Brink W, van Ree JM, Beijnen JH. Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature. Curr. Clin. Pharmacol. 1(1), 109-118 (2006
    • (2006) Curr. Clin. Pharmacol , vol.1 , Issue.1 , pp. 109-118
    • Rook, E.J.1    Huitema, A.D.R.2    Van Den Brink, W.3    Van Ree, J.M.4    Beijnen, J.H.5
  • 16
    • 0029738663 scopus 로고    scopus 로고
    • The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine
    • Milne RW, Nation RL, Somogyi AA. The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine. Drug Metab. Rev. 28(3), 345-472 (1996 (Pubitemid 26300413)
    • (1996) Drug Metabolism Reviews , vol.28 , Issue.3 , pp. 345-472
    • Milne, R.W.1    Nation, R.L.2    Somogyi, A.A.3
  • 18
    • 0031894377 scopus 로고    scopus 로고
    • The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
    • Coffman BL, King CD, Rios GR, Tephly TR. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab. Dispos. 26(1), 73-77 (1998 (Pubitemid 28071328)
    • (1998) Drug Metabolism and Disposition , vol.26 , Issue.1 , pp. 73-77
    • Coffman, B.L.1    King, C.D.2    Rios, G.R.3    Tephly, T.R.4
  • 20
    • 0017744829 scopus 로고
    • Isolation and identification of morphine 3- and 6-glucuronides, morphine 3,6-diglucuronide, morphine 3-ethereal sulfate, normorphine, and normorphine 6-glucuronide as morphine metabolites in humans
    • DOI 10.1002/jps.2600660921
    • Yeh SY, Gorodetzky CW, Krebs HA. Isolation and identification of morphine 3- and 6-glucuronides, morphine-3,6-diglucuronide, morphine 3-ethereal sulfate, normorphine, and normorphine 6-glucuronide as morphine metabolites in humans. J. Pharm. Sci. 66(9), 1288-1293 (1977 (Pubitemid 8163981)
    • (1977) Journal of Pharmaceutical Sciences , vol.66 , Issue.9 , pp. 1288-1293
    • Yeh, S.Y.1    Gorodetzky, C.W.2    Krebs, H.A.3
  • 21
    • 0141631451 scopus 로고    scopus 로고
    • Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes
    • DOI 10.1080/0049825031000121608
    • Projean D, Morin P-E, Tu TM, Ducharme J. Identification of CYP3A4 and CYP2C8 as the major cytochrome P450s responsible for morphine N-demethylation in human liver microsomes. Xenobiotica 33(8), 841-854 (2003 (Pubitemid 37129907)
    • (2003) Xenobiotica , vol.33 , Issue.8 , pp. 841-854
    • Projean, D.1    Morin, P.-E.2    Tu, T.M.3    Ducharme, J.4
  • 23
    • 0017585361 scopus 로고
    • Actions and metabolism of codeine (methylmorphine) administration by continuous intravenous infusion to humans
    • Nomof N, Elliott HW, Parker KD. Actions and metabolism of codeine (methylmorphine) administration by continuous intravenous infusion to humans. Clin. Toxicol. 11(5), 517-529 (1977 (Pubitemid 8305643)
    • (1977) Clinical Toxicology , vol.11 , Issue.5 , pp. 517-529
    • Nomof, N.1    Elliott, H.W.2    Parker, K.D.3
  • 24
    • 0030033493 scopus 로고    scopus 로고
    • Analgesic and immunomodulatory effects of codeine and codeine 6-glucuronide
    • DOI 10.1023/A:1016059618633
    • Srinivasan V, Wielbo D, Simpkins J, Karlix J, Sloan K, Tebbett I. Analgesic and immunomodulatory effects of codeine and codeine 6-glucuronide. Pharm. Res. 13(2), 296-300 (1996 (Pubitemid 26072151)
    • (1996) Pharmaceutical Research , vol.13 , Issue.2 , pp. 296-300
    • Srinivasan, V.1    Wielbo, D.2    Simpkins, J.3    Karlix, J.4    Sloan, K.5    Tebbett, I.6
  • 25
    • 0018750637 scopus 로고
    • Comparative metabolism of codeine in man, rat, dog, guinea-pig and rabbit: Identification of four new metabolites
    • Cone EJ, Darwin WD, Gorodetzky CW. Comparative metabolism of codeine in man, rat, dog, guinea-pig and rabbit: Identification of four new metabolites. J. Pharm. Pharmacol. 31, 314-317 (1979 (Pubitemid 9207596)
    • (1979) Journal of Pharmacy and Pharmacology , vol.31 , Issue.5 , pp. 314-317
    • Cone, E.J.1    Darwin, W.D.2    Gorodetzky, C.W.3
  • 26
    • 33646178983 scopus 로고    scopus 로고
    • Evidence of morphine metabolism to hydromorphone in pain patients chronically treated with morphine
    • Cone EJ, Heit HA, Yale HC, Gourlay D. Evidence of morphine metabolism to hydromorphone in pain patients chronically treated with morphine. J. Anal. Toxicol. 30(1), 1-6 (2006
    • (2006) J. Anal. Toxicol , vol.30 , Issue.1 , pp. 1-6
    • Cone, E.J.1    Heit, H.A.2    Yale, H.C.3    Gourlay, D.4
  • 27
    • 0033819965 scopus 로고    scopus 로고
    • Identification of hydrocodone in human urine following controlled codeine administration
    • Oyler JM, Cone EJ, Hoseph RE Jr, Huestis MA. Identification of hydrocodone in human urine following controlled codeine administration. J. Anal. Toxicol. 24(7), 530-535 (2000
    • (2000) J. Anal. Toxicol , vol.24 , Issue.7 , pp. 530-535
    • Oyler, J.M.1    Cone, E.J.2    Hoseph Jr., R.E.3    Huestis, M.A.4
  • 28
    • 0018142043 scopus 로고
    • Comparative metabolism of hydrocodone in man, rat, guinea pig, rabbit, and dog
    • Cone EJ, Darwin WD, Gorodetzky CW, Tan T. Comparative metabolism of hydrocodone in man, rat, guinea pig, rabbit and dog. Drug Metab. Dispos. 6(4), 488-493 (1978 (Pubitemid 8399700)
    • (1978) Drug Metabolism and Disposition , vol.6 , Issue.4 , pp. 488-493
    • Cone, E.J.1    Darwin, W.D.2    Gorodetzky, C.W.3    Tan, T.4
  • 30
    • 84870703709 scopus 로고    scopus 로고
    • Excretion profile of hydrocodone, hydromorphone and norhydrocodone in urine following single dose administration of hydrocodone to healthy volunteers
    • Valtier S, Bebarta VS. Excretion profile of hydrocodone, hydromorphone and norhydrocodone in urine following single dose administration of hydrocodone to healthy volunteers. J. Anal. Toxicol. 36(7), 507-514 (2012
    • (2012) J. Anal. Toxicol , vol.36 , Issue.7 , pp. 507-514
    • Valtier, S.1    Bebarta, V.S.2
  • 31
    • 0018174146 scopus 로고
    • Determination of oxycodone and a major metabolite in urine by electron-capture GLC
    • Baselt RC, Stewart CB. Determination of oxycodone and a major metabolite in urine by electron-capture GLC. J. Anal. Toxicol. 2(3), 107-109 (1978 (Pubitemid 8384715)
    • (1978) Journal of Analytical Toxicology , vol.2 , Issue.3 , pp. 107-109
    • Baselt, R.C.1    Stewart, C.B.2
  • 32
    • 33646183072 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites
    • Lalovic B, Kharasch E, Hoffer C, Risler L, Liu-Chen L-Y, Shen DD. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites. Clin. Pharmacol. Ther. 79(5), 461-479 (2006
    • (2006) Clin. Pharmacol. Ther , vol.79 , Issue.5 , pp. 461-479
    • Lalovic, B.1    Kharasch, E.2    Hoffer, C.3    Risler, L.4    Liu-Chen, L.-Y.5    Shen, D.D.6
  • 33
    • 84883004626 scopus 로고    scopus 로고
    • Prescription opioids I Metabolism and excretion patterns of oxycodone in urine following controlled single dose administration
    • Cone EJ, Heltsley R, Black DL, Mitchell JM, LoDico CP, Flegel RR. Prescription opioids. I. Metabolism and excretion patterns of oxycodone in urine following controlled single dose administration. J. Anal. Toxicol. 37(5), 255-264 (2013
    • (2013) J. Anal. Toxicol , vol.37 , Issue.5 , pp. 255-264
    • Cone, E.J.1    Heltsley, R.2    Black, D.L.3    Mitchell, J.M.4    LoDico, C.P.5    Flegel, R.R.6
  • 34
    • 0020601851 scopus 로고
    • Oxymorphone metabolism and urinary excretion in human, rat, guinea pig, rabbit, and dog
    • Cone EJ, Darwin WD, Buchwald WF, Gorodetzky CW. Oxymorphone metabolism and urinary excretion in human, rat, guinea-pig, rabbit, and dog. Drug Metab. Dispos. 11(5), 446-450 (1983 (Pubitemid 13021124)
    • (1983) Drug Metabolism and Disposition , vol.11 , Issue.5 , pp. 446-450
    • Cone, E.J.1    Darwin, W.D.2    Buchwald, W.F.3    Gorodetzky, C.W.4
  • 35
    • 0030774527 scopus 로고    scopus 로고
    • Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: Implications for interindividual variability in disposition, efficacy, and drug interactions
    • Labroo RB, Paine MF, Thummel KE, Kharasch ED. Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: Implications for interindividual variability in disposition, efficacy and drug interactions. Drug Metab. Dispos. 25(9), 1072-1080 (1997 (Pubitemid 27396495)
    • (1997) Drug Metabolism and Disposition , vol.25 , Issue.9 , pp. 1072-1080
    • Labroo, R.B.1    Paine, M.F.2    Thummel, K.E.3    Kharasch, E.D.4
  • 36
    • 84877851541 scopus 로고    scopus 로고
    • Metabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: Methadone and buprenorphine
    • Moody DE. Metabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: Methadone and buprenorphine. Expert Opin. Drug Metab. Toxicol. 9(6), 675-697 (2013
    • (2013) Expert Opin. Drug Metab. Toxicol , vol.9 , Issue.6 , pp. 675-697
    • Moody, D.E.1
  • 37
    • 85027916764 scopus 로고    scopus 로고
    • Steps physicians report taking to reduce diversion of buprenorphine
    • Yang A, Arfken CL, Johanson C-E. Steps physicians report taking to reduce diversion of buprenorphine. Am. J. Addict. 22(3), 184-187 (2013
    • (2013) Am. J. Addict , vol.22 , Issue.3 , pp. 184-187
    • Yang, A.1    Arfken, C.L.2    Johanson, C.-E.3
  • 39
    • 33646557959 scopus 로고    scopus 로고
    • Does random urine drug testing reduce illicit drug use in chronic pain patients receiving opioids?
    • Manchikanti L, Manchukonda R, Pampati V et al Does random urine drug testing reduce illicit drug use in chronic pain patients receiving opioids? Pain Physician 9(2), 123-129 (2006
    • (2006) Pain Physician , vol.9 , Issue.2 , pp. 123-129
    • Manchikanti, L.1    Manchukonda, R.2    Pampati, V.3
  • 40
    • 0036329422 scopus 로고    scopus 로고
    • Role of urine toxicology testing in the management of chronic opioid therapy
    • DOI 10.1097/00002508-200207001-00009
    • Katz N, Fanciullo GJ. Role of urine toxicology testing in the management of chronic opioid therapy. Clin. J. Pain 18(4 Suppl.), S76-S82 (2002 (Pubitemid 34815397)
    • (2002) Clinical Journal of Pain , vol.18 , Issue.4 SUPPL.
    • Katz, N.1    Fanciullo, G.J.2    Jamison, R.N.3
  • 41
  • 42
    • 78650149855 scopus 로고    scopus 로고
    • False-positive' and 'false-negative' test results in clinical urine drug testing
    • Reisfield GM, Goldberger BA, Bertholf RL. 'False-positive' and 'false-negative' test results in clinical urine drug testing. Bioanalysis 1(5), 937-952 (2009
    • (2009) Bioanalysis , vol.1 , Issue.5 , pp. 937-952
    • Reisfield, G.M.1    Goldberger, B.A.2    Bertholf, R.L.3
  • 43
    • 0037372778 scopus 로고    scopus 로고
    • National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Recommendations for the use of laboratory tests to support poisoned patients who present to the emergency department
    • DOI 10.1373/49.3.357
    • Wu AHB, McKay C, Broussard LA et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Recommendations for the use of laboratory tests to support poisoned patients who present to the emergency department. Clin. Chem. 49(3), 357-379 (2003 (Pubitemid 36250197)
    • (2003) Clinical Chemistry , vol.49 , Issue.3 , pp. 357-379
    • Wu, A.H.B.1    McKay, C.2    Broussard, L.A.3    Hoffman, R.S.4    Kwong, T.C.5    Moyer, T.P.6    Otten, E.M.7    Welch, S.L.8    Wax, P.9
  • 44
    • 75749122658 scopus 로고    scopus 로고
    • Beating the system: A study of a creatinine assay and its efficacy in authenticating human urine specimens
    • Villena VP. Beating the system: A study of a creatinine assay and its efficacy in authenticating human urine specimens. J. Anal. Toxicol. 34(1), 39-44 (2010
    • (2010) J. Anal. Toxicol , vol.34 , Issue.1 , pp. 39-44
    • Villena, V.P.1
  • 45
    • 0033814551 scopus 로고    scopus 로고
    • The characterization of human urine for specimen validity determination in workplace drug testing: A review
    • Cook JD, Caplan YH, LoDico CP, Bush DM. The characterization of human urine for specimen validity determination in workplace drug testing: A review. J. Anal. Toxicol. 24(7), 579-588 (2000
    • (2000) J. Anal. Toxicol , vol.24 , Issue.7 , pp. 579-588
    • Cook, J.D.1    Caplan, Y.H.2    LoDico, C.P.3    Bush, D.M.4
  • 46
    • 58149512344 scopus 로고    scopus 로고
    • Criteria for opiate identification using liquid chromatography linked to tandem mass spectrometry: Problems in routine practice
    • Fox EJ, Twigger S, Allen KR. Criteria for opiate identification using liquid chromatography linked to tandem mass spectrometry: Problems in routine practice. Ann. Clin. Biochem. 46(Pt 1), 50-57 (2009
    • (2009) Ann. Clin. Biochem , vol.46 , Issue.PART 1 , pp. 50-57
    • Fox, E.J.1    Twigger, S.2    Allen, K.R.3
  • 47
    • 82955205886 scopus 로고    scopus 로고
    • Hydrophilic interaction LC-MS/MS analysis of opioids in urine: Significance of glucuronide metabolites
    • French D, Wu AHB, Lynch K. Hydrophilic interaction LC-MS/MS analysis of opioids in urine: Significance of glucuronide metabolites. Bioanalysis 3(23), 2603-2612 (2011
    • (2011) Bioanalysis , vol.3 , Issue.23 , pp. 2603-2612
    • French, D.1    Wu, A.H.B.2    Lynch, K.3
  • 48
    • 84867663548 scopus 로고    scopus 로고
    • Improved detection of opioid use in chronic pain patients through monitoring of opioid glucuronides in urine
    • Dickerson JA, Laha TJ, Pagano MB, O'Donnell BR, Hoofnagle AN. Improved detection of opioid use in chronic pain patients through monitoring of opioid glucuronides in urine. J. Anal. Toxicol. 36(8), 541-547 (2012
    • (2012) J. Anal. Toxicol , vol.36 , Issue.8 , pp. 541-547
    • Dickerson, J.A.1    Laha, T.J.2    Pagano, M.B.3    O'Donnell, B.R.4    Hoofnagle, A.N.5
  • 49
    • 0038574979 scopus 로고    scopus 로고
    • Ion suppression in mass spectrometry
    • DOI 10.1373/49.7.1041
    • Annesley TM. Ion suppression in mass spectrometry. Clin. Chem. 49(7), 1041-1044 (2003 (Pubitemid 36751088)
    • (2003) Clinical Chemistry , vol.49 , Issue.7 , pp. 1041-1044
    • Annesley, T.M.1
  • 50
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
    • DOI 10.1021/ac020361s
    • Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal. Chem. 75(13), 3019-3030 (2003 (Pubitemid 36830428)
    • (2003) Analytical Chemistry , vol.75 , Issue.13 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 51
    • 0142195729 scopus 로고    scopus 로고
    • Matrix effect in bio-analysis of illicit drugs with LC-MS/MS: Influence of ionization type, sample preparation, and biofluid
    • DOI 10.1016/S1044-0305(03)00574-9
    • Dams R, Huestis MA, Lambert WE, Murphy CM. Matrix effect in bioanalysis of illicit drugs with LC-MS/MS: Influence of ionization type, sample preparation and biofluid. J. Am. Soc. Mass Spectrom. 14(11), 1290-1294 (2003 (Pubitemid 37330133)
    • (2003) Journal of the American Society for Mass Spectrometry , vol.14 , Issue.11 , pp. 1290-1294
    • Dams, R.1    Huestis, M.A.2    Lambert, W.E.3    Murphy, C.M.4
  • 52
    • 0027956422 scopus 로고
    • Confirmatory tests for drugs in the workplace by gas chromatography-mass spectrometry
    • DOI 10.1016/0021-9673(94)85218-9
    • Goldberger BA, Cone EJ. Confirmatory tests for drugs in the workplace by gas chromatography-mass spectrometry. J. Chromatogr. A 674(1-2), 73-86 (1994 (Pubitemid 24244769)
    • (1994) Journal of Chromatography A , vol.674 , Issue.1-2 , pp. 73-86
    • Goldberger, B.A.1    Cone, E.J.2
  • 53
    • 0344678331 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry: Potential in forensic and clinical toxicology
    • Marquet P, Lachâtre G. Liquid chromatography-mass spectrometry: Potential in forensic and clinical toxicology. J. Chromatogr. B Biomed. Sci. Appl. 733(1-2), 93-118 (1999
    • (1999) J. Chromatogr. B Biomed. Sci. Appl , vol.733 , pp. 93-118
    • Marquet, P.1    Lachâtre, G.2
  • 54
    • 75749140124 scopus 로고    scopus 로고
    • Urine drug testing of chronic pain patients II Prevalence patterns of prescription opiates and metabolites
    • Heltsley R, Zichterman A, Black DL et al. Urine drug testing of chronic pain patients. II. Prevalence patterns of prescription opiates and metabolites. J. Anal. Toxicol. 34, 32-38 (2010
    • (2010) J. Anal. Toxicol , vol.34 , pp. 32-38
    • Heltsley, R.1    Zichterman, A.2    Black, D.L.3
  • 55
    • 77952288931 scopus 로고    scopus 로고
    • Urine testing for norcodeine, norhydrodone, and noroxycodone facilitates interpretation and reduces false negatives
    • Cone EJ, Zichterman A, Heltsley R et al. Urine testing for norcodeine, norhydrodone, and noroxycodone facilitates interpretation and reduces false negatives. Forensic Sci. Int. 198(1), 58-61 (2010
    • (2010) Forensic Sci. Int , vol.198 , Issue.1 , pp. 58-61
    • Cone, E.J.1    Zichterman, A.2    Heltsley, R.3
  • 56
    • 37349099727 scopus 로고    scopus 로고
    • Determination of illicit drugs and their metabolites in human urine by liquid chromatography tandem mass spectrometry including relative ion intensity criterion
    • Concheiro M, Castro AD, Quintela O, Cruz A, López-Rivadulla M. Determination of illicit drugs and their metabolites in human urine by liquid chromatography tandem mass spectrometry including relative ion intensity criteria. J. Anal. Toxicol. 31(9), 573-580 (2007 (Pubitemid 350291669)
    • (2007) Journal of Analytical Toxicology , vol.31 , Issue.9 , pp. 573-580
    • Concheiro, M.1    De Castro, A.2    Quintela, O.3    Cruz, A.4    Lopez-Rivadulla, M.5
  • 57
    • 84862615124 scopus 로고    scopus 로고
    • Dilute and shoot: Analysis of drugs of abuse using selected reaction monitoring for quantification and full scan product ion spectra for identification
    • Fitzgerald RL, Griffin TL, Yun Y-M et al. Dilute and shoot: Analysis of drugs of abuse using selected reaction monitoring for quantification and full scan product ion spectra for identification. J. Anal. Toxicol. 36, 106-111 (2012
    • (2012) J. Anal. Toxicol , vol.36 , pp. 106-111
    • Fitzgerald, R.L.1    Griffin, T.L.2    Yun, Y.-M.3
  • 58
    • 0037932381 scopus 로고    scopus 로고
    • Urine drug testing for opioids, cocaine, and metabolites by direct injection liquid chromatography/tandem mass spectrometry
    • Dams R, Murphy CM, Lambert WE, Huestis MA. Urine drug testing for opioids, cocaine and metabolites by direct injection liquid chromatography/ tandem mass spectrometry. Rapid Commun. Mass Spectrom. 17(14), 1665-1670 (2003 (Pubitemid 36841349)
    • (2003) Rapid Communications in Mass Spectrometry , vol.17 , Issue.14 , pp. 1665-1670
    • Dams, R.1    Murphy, C.M.2    Lambert, W.E.3    Huestis, M.A.4
  • 59
    • 75749092990 scopus 로고    scopus 로고
    • Simultaneous liquid chromatography-mass spectrometry quantification of urinary opiates, cocaine, and metabolites in opiate-dependent pregnant women in methadone-maintenance treatment
    • Shakleya DM, Dams R, Choo RE, Jones H, Huestis MA. Simultaneous liquid chromatography-mass spectrometry quantification of urinary opiates, cocaine, and metabolites in opiate-dependent pregnant women in methadone-maintenance treatment. J. Anal. Toxicol. 34(1), 17-25 (2010
    • (2010) J. Anal. Toxicol , vol.34 , Issue.1 , pp. 17-25
    • Shakleya, D.M.1    Dams, R.2    Choo, R.E.3    Jones, H.4    Huestis, M.A.5
  • 60
    • 77957655311 scopus 로고    scopus 로고
    • A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-Triple quadrupole mass spectrometer
    • Dowling G, Regan L, Tierney J, Nangle M. A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-Triple quadrupole mass spectrometer. J. Chromatogr. A 1217(44), 6857-6866 (2010
    • (2010) J. Chromatogr , vol.A1217 , Issue.44 , pp. 6857-6866
    • Dowling, G.1    Regan, L.2    Tierney, J.3    Nangle, M.4
  • 61
    • 29144475156 scopus 로고    scopus 로고
    • Direct analysis of opiates in urine by liquid chromatography - Tandem mass spectrometry
    • Edinboro LE, Backer RC, Poklis A. Direct ana¬lysis of opiates in urine by liquid chromatography-Tandem mass spectrometry. J. Anal. Toxicol. 29(7), 704-710 (2005 (Pubitemid 41803361)
    • (2005) Journal of Analytical Toxicology , vol.29 , Issue.7 , pp. 704-710
    • Edinboro, L.E.1    Backer, R.C.2    Poklis, A.3
  • 62
    • 47749148401 scopus 로고    scopus 로고
    • A high-throughput multicomponent screening method for diuretics, masking agents, central nervous system (CNS) stimulants and opiates in human urine by UPLC-MS/MS
    • DOI 10.1002/jms.1436
    • Thörngren J-O, Östervall F, Garle M. A high-Throughput multicomponent screening method for diuretics, masking agents, central nervous system (CNS) stimulants and opiates in human urine by UPLC-MS/MS. J. Mass Spectrom. 43(7), 980-992 (2008 (Pubitemid 352029667)
    • (2008) Journal of Mass Spectrometry , vol.43 , Issue.7 , pp. 980-992
    • Thorngren, J.-O.1    Ostervall, F.2    Garle, M.3
  • 63
    • 34447327514 scopus 로고    scopus 로고
    • Validation of direct injection electrospray LC-MS/MS for confirmation of opiates in urine drug testing
    • DOI 10.1002/jms.1219
    • Gustavsson E, Andersson M, Stephanson N, Beck O. Validation of direct injection electrospray LC-MS/MS for confirmation of opiates in urine drug testing. J. Mass Spectrom. 42(7), 881-889 (2007 (Pubitemid 47057070)
    • (2007) Journal of Mass Spectrometry , vol.42 , Issue.7 , pp. 881-889
    • Gustavsson, E.1    Andersson, M.2    Stephanson, N.3    Beck, O.4
  • 64
    • 0032986050 scopus 로고    scopus 로고
    • The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds
    • DOI 10.1002 /(SICI) 1097-0231 (19990630)13:12<1175::AID-RCM639>3.0. CO;2-0
    • Bonfiglio R, King RC, Olah TV, Merkle K. The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds. Rapid Commun. Mass Spectrom. 13(12), 1175-1185 (1999 (Pubitemid 29285118)
    • (1999) Rapid Communications in Mass Spectrometry , vol.13 , Issue.12 , pp. 1175-1185
    • Bonfiglio, R.1    King, R.C.2    Olah, T.V.3    Merkle, K.4
  • 65
    • 27944505459 scopus 로고    scopus 로고
    • LC-ESI-MS/MS analysis for the quantification of morphine, codeine, morphine-3-β-D-glucuronide, morphine-6-β-D-glucuronide, and codeine-6-β-D-glucuronide in human urine
    • DOI 10.1002/jms.921
    • Murphy CM, Huestis MA. LC-ESI-MS/MS ana¬lysis for the quantification of morphine, codeine, morphine-3-b-d-glucuronide, morphine-6-b-d-glucuronide, and codeine-6-b-d-glucuronide in human urine. J. Mass Spectrom. 40, 1412-1416 (2005 (Pubitemid 41667204)
    • (2005) Journal of Mass Spectrometry , vol.40 , Issue.11 , pp. 1412-1416
    • Murphy, C.M.1    Huestis, M.A.2
  • 66
    • 33847697700 scopus 로고    scopus 로고
    • Simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, oxycodone and 6-Acetylmorphine in urine, serum, plasma, whole blood, and meconium by LC-MS-MS
    • Coles R, Kushnir MM, Nelson GJ, McMillin GA, Urry FM. Simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, oxycodone and 6-Acetylmorphine in urine, serum, plasma, whole blood, and meconium by LC-MS-MS. J. Anal. Toxicol. 31(1), 1-10 (2007
    • (2007) J. Anal. Toxicol , vol.31 , Issue.1 , pp. 1-10
    • Coles, R.1    Kushnir, M.M.2    Nelson, G.J.3    McMillin, G.A.4    Urry, F.M.5
  • 68
    • 84862621692 scopus 로고    scopus 로고
    • Patterns of free (unconjugated) buprenorphine, norbuprenorphine and their glucuronides in urine using liquid chromatography-Tandem mass spectrometry
    • McMillin GA, Davis R, Carlisle H, Clark C, Marin SJ, Moody DE. Patterns of free (unconjugated) buprenorphine, norbuprenorphine and their glucuronides in urine using liquid chromatography-Tandem mass spectrometry. J. Anal. Toxicol. 36(2), 81-87 (2012
    • (2012) J. Anal. Toxicol , vol.36 , Issue.2 , pp. 81-87
    • McMillin, G.A.1    Davis, R.2    Carlisle, H.3    Clark, C.4    Marin, S.J.5    Moody, D.E.6
  • 69
    • 33745792137 scopus 로고    scopus 로고
    • An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites
    • DOI 10.1002/jms.1021
    • Musshoff F, Trafkowski J, Kuepper U, Madea B. An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites. J. Mass Spectrom. 41(5), 633-640 (2006 (Pubitemid 44023118)
    • (2006) Journal of Mass Spectrometry , vol.41 , Issue.5 , pp. 633-640
    • Musshoff, F.1    Trafkowski, J.2    Kuepper, U.3    Madea, B.4
  • 70
    • 5344275249 scopus 로고    scopus 로고
    • Confirmatory analysis for drugs of abuse in plasma and urine by high-performance liquid chromatography-tandem mass spectrometry with respect to criteria for compound identification
    • DOI 10.1016/j.jchromb.2004.04.039, PII S1570023204006427
    • Maralikova B, Weinmann W. Confirmatory analysis for drugs of abuse in plasma and urine by high-performance liquid chromatography-Tandem mass spectrometry with respect to criteria for compound identification. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 811(1), 21-30 (2004 (Pubitemid 39348844)
    • (2004) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.811 , Issue.1 SPEC. ISSUE. , pp. 21-30
    • Maralikova, B.1    Weinmann, W.2
  • 71
    • 84860389784 scopus 로고    scopus 로고
    • Online extraction LC-MS/MS method for simultaneous quantitative confirmation of urine drugs of abuse and metabolites: Amphetamines, opiates, cocaine, cannabis, benzodiazepines and methadone
    • de Jager AD, Bailey NL. Online extraction LC-MS/MS method for simultaneous quantitative confirmation of urine drugs of abuse and metabolites: Amphetamines, opiates, cocaine, cannabis, benzodiazepines and methadone. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879(29), 2642-2652 (2011
    • (2011) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.879 , Issue.29 , pp. 2642-2652
    • De Jager, A.D.1    Bailey, N.L.2
  • 72
    • 39649104093 scopus 로고    scopus 로고
    • Online solid-phase extraction liquid chromatography-electrospray-Tandem mass spectrometry analysis of buprenorphine and three metabolites in human urine
    • Liu A-C, Lin T-Y, Su L-W, Fuh M-R. Online solid-phase extraction liquid chromatography-electrospray-Tandem mass spectrometry analysis of buprenorphine and three metabolites in human urine. Talanta 75(1), 198-204 (2008
    • (2008) Talanta , vol.75 , Issue.1 , pp. 198-204
    • Liu, A.-C.1    Lin, T.-Y.2    Su, L.-W.3    Fuh, M.-R.4
  • 73
    • 84872351736 scopus 로고    scopus 로고
    • Development and validation of twoLC-MS/MS methods for the detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and opioids in urine using turbulent flow chromatography
    • Schaefer N, Peters B, Schmidt P, Ewald AH. Development and validation of twoLC-MS/MS methods for the detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and opioids in urine using turbulent flow chromatography. Anal. Bioanal. Chem. 405(1), 247-258 (2013
    • (2013) Anal. Bioanal. Chem , vol.405 , Issue.1 , pp. 247-258
    • Schaefer, N.1    Peters, B.2    Schmidt, P.3    Ewald, A.H.4
  • 74
    • 33748471966 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography
    • DOI 10.1002/jssc.200600199
    • Hemström P, Irqum K. Hydrophilic interaction chromatography. J. Sep. Sci. 29(12), 1784-1821 (2006 (Pubitemid 44348484)
    • (2006) Journal of Separation Science , vol.29 , Issue.12 , pp. 1784-1821
    • Hemstrom, P.1    Irgum, K.2
  • 75
    • 0018567422 scopus 로고
    • Practical aspects of reversed-phase liquid chromatography applied to biochemical and biomedical research
    • DOI 10.1016/0003-2697(79)90038-1
    • Brown PR, Krstulovic AM. Practical aspects of reversed-phase liquid chromatography applied to biochemical and biomedical research. Anal. Biochem. 99(1), 1-21 (1979 (Pubitemid 10197701)
    • (1979) Analytical Biochemistry , vol.99 , Issue.1 , pp. 1-21
    • Brown, P.R.1    Krstulovic, A.M.2
  • 76
    • 77950811207 scopus 로고    scopus 로고
    • Recent advances in application of hydrophilic interaction chromatography for quantitative analysis
    • Jian W, Edom RW, Xu Y, Weng N. Recent advances in application of hydrophilic interaction chromatography for quantitative analysis. J. Sep. Sci. 33, 681-697 (2010
    • (2010) J. Sep. Sci , vol.33 , pp. 681-697
    • Jian, W.1    Edom, R.W.2    Xu, Y.3    Weng, N.4
  • 77
    • 79955365485 scopus 로고    scopus 로고
    • Analysis of polar metabolites by hydrophilic interaction chromatography-MS/MS
    • Jian W, Xu Y, Edom RW, Weng N. Analysis of polar metabolites by hydrophilic interaction chromatography-MS/MS. Bioanalysis 3(8), 899-912 (2011
    • (2011) Bioanalysis , vol.3 , Issue.8 , pp. 899-912
    • Jian, W.1    Xu, Y.2    Edom, R.W.3    Weng, N.4
  • 78
    • 0021184489 scopus 로고
    • The metabolism and excretion of buprenorphine in humans
    • Cone EJ, Gorodetzky CW, Yousefnejad D, Buchwald WF, Johnson RE. The metabolism and excretion of buprenorphine in humans. Drug Metab. Dispos. 12(5), 577-581 (1984 (Pubitemid 14020828)
    • (1984) Drug Metabolism and Disposition , vol.12 , Issue.5 , pp. 577-581
    • Cone, E.J.1    Gorodetzky, C.W.2    Yousefnejad, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.