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Volumn 3, Issue 23, 2011, Pages 2603-2612

Hydrophilic interaction LC-MS/MS analysis of opioids in urine: Significance of glucuronide metabolites

Author keywords

[No Author keywords available]

Indexed keywords

CODEINE; CODEINE 6 BETA DEXTRO GLUCURONIDE; DRUG METABOLITE; HYDROCODONE; HYDROMORPHONE; HYDROMORPHONE 6 BETA DEXTRO GLUCURONIDE; MORPHINE; MORPHINE 6 GLUCURONIDE; NARCOTIC ANALGESIC AGENT; OXYCODONE; OXYMORPHONE; OXYMORPHONE 6 BETA DEXTRO GLUCURONIDE; UNCLASSIFIED DRUG;

EID: 82955205886     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.266     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 0029738663 scopus 로고    scopus 로고
    • The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine
    • Milne RW, Nation RL, Somogyi AA. The disposition of morphine and its 3-and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine. Drug Metab. Rev. 28(3), 345-472 (1996). (Pubitemid 26300413)
    • (1996) Drug Metabolism Reviews , vol.28 , Issue.3 , pp. 345-472
    • Milne, R.W.1    Nation, R.L.2    Somogyi, A.A.3
  • 4
    • 0017585361 scopus 로고
    • Actions and metabolism of codeine (methylmorphine) administration by continuous intravenous infusion to humans
    • Nomof H, Elliott H W, Parker KD. Actions and metabolism of codeine (methylmorphine) administration by continuous intravenous infusion to humans. Clin. Toxicol. 11, 517-529 (1977). (Pubitemid 8305643)
    • (1977) Clinical Toxicology , vol.11 , Issue.5 , pp. 517-529
    • Nomof, N.1    Elliott, H.W.2    Parker, K.D.3
  • 7
    • 0031894377 scopus 로고    scopus 로고
    • The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
    • Coffman BL, King CD, Rios GR, Tephly TR. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab. Dispos. 26(1), 73-77 (1998). (Pubitemid 28071328)
    • (1998) Drug Metabolism and Disposition , vol.26 , Issue.1 , pp. 73-77
    • Coffman, B.L.1    King, C.D.2    Rios, G.R.3    Tephly, T.R.4
  • 8
    • 0033645752 scopus 로고    scopus 로고
    • Genetic polymorphism of udp-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: Ethnic diversity of alleles and potential clinical signifcance
    • Bhasker CR, McKinnon W, Stone A et al. Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical signifcance. Pharmacogenetics 10(8), 679-685 (2000).
    • (2000) Pharmacogenetics , vol.10 , Issue.8 , pp. 679-685
    • Bhasker, C.R.1    McKinnon, W.2    Stone, A.3
  • 9
    • 33644958925 scopus 로고    scopus 로고
    • Haplotype analysis of udp-glucuronosyltransferase 2B7 gene (UGT2B7) polymorphisms in healthy japanese subjects
    • Saito K, Moriya H, Sawaguchi T et al. Haplotype analysis of UDP-glucuronosyltransferase 2B7 gene (UGT2B7) polymorphisms in healthy Japanese subjects. Clin. Biochem. 39(3), 303-308 (2006).
    • (2006) Clin. Biochem. , vol.39 , Issue.3 , pp. 303-308
    • Saito, K.1    Moriya, H.2    Sawaguchi, T.3
  • 10
    • 0742286803 scopus 로고    scopus 로고
    • Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
    • DOI 10.1007/s00210-003-0832-2
    • Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics and biochemistry. Naunyn Schmiedebergs Arch. Pharmacol. 369, 23-37 (2004). (Pubitemid 38161221)
    • (2004) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.369 , Issue.1 , pp. 23-37
    • Zanger, U.M.1    Raimundo, S.2    Eichelbaum, M.3
  • 11
    • 33646178983 scopus 로고    scopus 로고
    • Evidence of morphine metabolism to hydromorphone in pain patients chronically treated with morphine
    • Cone EJ, Heit HA, Yale HC, Gourlay D. Evidence of morphine metabolism to hydromorphone in pain patients chronically treated with morphine. J. Anal. Toxicol. 30(1), 1-6 (2006).
    • (2006) J. Anal. Toxicol. , vol.30 , Issue.1 , pp. 1-6
    • Cone, E.J.1    Heit, H.A.2    Yale, H.C.3    Gourlay, D.4
  • 12
    • 0033819965 scopus 로고    scopus 로고
    • Identifcation of hydrocodone in human urine following controlled codeine administration
    • Oyler JM, Cone EJ, Hoseph RE Jr, Huestis MA. Identifcation of hydrocodone in human urine following controlled codeine administration. J. Anal. Toxicol. 24(7), 530-535 (2000).
    • (2000) J. Anal. Toxicol. , vol.24 , Issue.7 , pp. 530-535
    • Oyler, J.M.1    Cone, E.J.2    Hoseph Jr., R.E.3    Huestis, M.A.4
  • 13
    • 0018174146 scopus 로고
    • Determination of oxycodone and a major metabolite in urine by electron-capture GLC
    • Baselt RC, Stewart CB. Determination of oxycodone and a major metabolite in urine by electron-capture GLC. J. Anal. Toxicol. 2(3), 107-109 (1978). (Pubitemid 8384715)
    • (1978) Journal of Analytical Toxicology , vol.2 , Issue.3 , pp. 107-109
    • Baselt, R.C.1    Stewart, C.B.2
  • 14
    • 75749092990 scopus 로고    scopus 로고
    • Simultaneous liquid chromatography-ms quantifcation of urinary opiates, cocaine and metabolites in opiate-dependent pregnant women in methadone-maintenance treatment
    • Shakleya DM, Dams R, Choo RE, Jones H. Huestis MA. Simultaneous liquid chromatography-MS quantifcation of urinary opiates, cocaine and metabolites in opiate-dependent pregnant women in methadone-maintenance treatment. J. Anal. Toxicol. 34, 17-25 (2010).
    • (2010) J. Anal. Toxicol. , vol.34 , pp. 17-25
    • Shakleya, D.M.1    Dams, R.2    Choo, R.E.3    Jones, H.4    Huestis, M.A.5
  • 15
    • 33847697700 scopus 로고    scopus 로고
    • Simultaneous determination of codeine morphine hydrocodone hydromorphone oxycodone 6-acetylmorphine in urine serum plasma, whole blood and meconium by lc-ms/ms
    • Coles R, Kushnir MM, Nelson GJ, McMillin GW, Urry FM. Simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, oxycodone and 6-acetylmorphine in urine, serum, plasma, whole blood and meconium by LC-MS/MS. J. Anal. Toxicol. 31, 1-14 (2007).
    • (2007) J. Anal. Toxicol. , vol.31 , pp. 1-14
    • Coles, R.1    Kushnir, M.M.2    Nelson, G.J.3    McMillin, G.W.4    Urry, F.M.5
  • 16
    • 58349090627 scopus 로고    scopus 로고
    • Determination of opiates and cocaine in urine by high ph mobile phase reversed phase uplc-ms/ms
    • Berg T, Lundanes E, Christophersen AS, Strand DH. Determination of opiates and cocaine in urine by high pH mobile phase reversed phase UPLC-MS/MS. J. Chromatog B 877, 421-432 (2009).
    • (2009) J. Chromatog B , vol.877 , pp. 421-432
    • Berg, T.1    Lundanes, E.2    Christophersen, A.S.3    Strand, D.H.4
  • 17
    • 34147149612 scopus 로고    scopus 로고
    • Electrospray LC-MS method with solid-phase extraction for accurate determination of morphine-, codeine-, and ethylmorphine-glucuronides and 6-acetylmorphine in urine
    • Svensson JO, Andersson M, Gustavsson E, Beck O. Electrospray LC-MS method with solid-phase extraction for accurate determination of morphine-, codeine-and ethylmorphine-glucuronides and 6-acetylmorphine in urine. J. Anal. Toxicol. 31, 81-86 (2007). (Pubitemid 46557478)
    • (2007) Journal of Analytical Toxicology , vol.31 , Issue.2 , pp. 81-86
    • Svensson, J.-O.1    Andersson, M.2    Gustavsson, E.3    Beck, O.4
  • 18
    • 0037932381 scopus 로고    scopus 로고
    • Urine drug testing for opioids, cocaine, and metabolites by direct injection liquid chromatography/tandem mass spectrometry
    • Dams R, Murphy CM, Lambert WE, Huestis MA. Urine drug testing for opioids, cocaine and metabolites by direct injection liquid chromatography- tandem MS. Rapid Commun. Mass Spectrom. 17, 1665-1670 (2003). (Pubitemid 36841349)
    • (2003) Rapid Communications in Mass Spectrometry , vol.17 , Issue.14 , pp. 1665-1670
    • Dams, R.1    Murphy, C.M.2    Lambert, W.E.3    Huestis, M.A.4
  • 19
    • 84860389784 scopus 로고    scopus 로고
    • Online extraction lc-ms/ms method for the simultaneous quantitative confrmation of urine drugs of abuse and metabolites: Amphetamines, opiates, cocaine, cannabis, benzodiazepines and methadone
    • de Jager AD, Bailey NL. Online extraction LC-MS/MS method for the simultaneous quantitative confrmation of urine drugs of abuse and metabolites: amphetamines, opiates, cocaine, cannabis, benzodiazepines and methadone. J. Chromatog. B 879, 2642-2652 (2011).
    • (2011) J. Chromatog. B , vol.879 , pp. 2642-2652
    • De Jager, A.D.1    Bailey, N.L.2
  • 20
    • 27944505459 scopus 로고    scopus 로고
    • Lc-esi-ms/ms analysis for the quantifcation of morphine, codeine, morphine-3-p-d-glucuronide, morphine-6-p-d-glucuronide and codeine-6-p-d- glucuronide in human urine
    • Murphy CM, Huestis MA. LC-ESI-MS/MS analysis for the quantifcation of morphine, codeine, morphine-3-p-D-glucuronide, morphine-6-p-D-glucuronide and codeine-6-p-D-glucuronide in human urine. J. Mass Spectrom. 40, 1412-1416 (2005).
    • (2005) J. Mass Spectrom. , vol.40 , pp. 1412-1416
    • Murphy, C.M.1    Huestis, M.A.2
  • 22
    • 0032984647 scopus 로고    scopus 로고
    • GC-MS confrmation of codeine, morphine 6-Acetylmorphine, hydrocodone, hydromorphone, oxycodone and oxymorphone in urine
    • Meatherall R. GC-MS confrmation of codeine, morphine 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone and oxymorphone in urine. J. Anal. Toxicol. 23(3), 177-186 (1999).
    • (1999) J. Anal. Toxicol. , vol.23 , Issue.3 , pp. 177-186
    • Meatherall, R.1
  • 23
    • 0027180160 scopus 로고
    • The quantitative conversion of morphine 3-β-D glucuronide to morphine using β-glucuronidase obtained from Patella vulgata as compared to acid hydrolysis
    • Jennison TA, Wozniak E, Nelson G, Urry FM. The quantitative conversion of morphine-3-b-D-glucuronide to morphine using beta-glucuronidase obtained from Patella vulgata as compared to acid hydrolysis. J. Anal. Toxicol. 17(4), 208-210 (1993). (Pubitemid 23212199)
    • (1993) Journal of Analytical Toxicology , vol.17 , Issue.4 , pp. 208-210
    • Jennison, T.A.1    Wozniak, E.2    Nelson, G.3    Urry, F.M.4
  • 25
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
    • DOI 10.1021/ac020361s
    • Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal. Chem. 75, 3019-3030 (2003). (Pubitemid 36830428)
    • (2003) Analytical Chemistry , vol.75 , Issue.13 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 26
    • 0242408853 scopus 로고    scopus 로고
    • High levels of morphine-6-glucuronide in street heroin addicts
    • DOI 10.1007/s00213-003-1531-x
    • Antonilli L, Semeraro F, Suriano C, Signore L, Nencini P. High levels of morphone-6-glucuronide in street heroin addicts. Psychopharmacol. 170, 200-204 (2003). (Pubitemid 37421531)
    • (2003) Psychopharmacology , vol.170 , Issue.2 , pp. 200-204
    • Antonilli, L.1    Semeraro, F.2    Suriano, C.3    Signore, L.4    Nencini, P.5
  • 27
    • 82955247369 scopus 로고    scopus 로고
    • Disposition of Toxic Drugs Chemicals in Man.(7th Edition)
    • Foster City CA USA2004
    • Baselt, RC. Disposition of Toxic Drugs and Chemicals in Man. (7th Edition). Biomedical Publications, Foster City, CA, USA2004.
    • Biomedical Publications
    • Baselt, R.C.1
  • 29
    • 0031449611 scopus 로고    scopus 로고
    • Determination of morphine and its 3- and 6-glucuronides, codeine, codeine-glucuronide and 6-monoacetylmorphine in body fluids by liquid chromatography atmospheric pressure chemical ionization mass spectrometry
    • DOI 10.1016/S0378-4347(97)00384-8, PII S0378434797003848
    • Bogusz MJ, Maier R-D, Erkens M, Driessen S. Determination of morphine and its 3-and 6-glucuronides, codeine, codeine-glucuronide and 6-monoacetylmorphine in body fuids by liquid chromatography atmospheric pressure chemical ionization MS. J. Chromatog. B 703, 115-127 (1997). (Pubitemid 28011250)
    • (1997) Journal of Chromatography B: Biomedical Applications , vol.703 , Issue.1-2 , pp. 115-127
    • Bogusz, M.J.1    Maier, R.-D.2    Erkens, M.3    Driessen, S.4
  • 30
    • 34249937715 scopus 로고    scopus 로고
    • Morphine glucuronosyltransferase activity in human liver microsomes is inhibited by a variety of drugs that are co-administered with morphine
    • Hara Y, Nakajima M, Miyamoto K, Yokoi T. Morphine glucuronosyltransferase activity in human liver microsomes is inhibited by a variety of drugs that are co-administered with morphine. Drug Metab. Pharmacokinet. 22, 103-112 (2007).
    • (2007) Drug Metab. Pharmacokinet. , vol.22 , pp. 103-112
    • Hara, Y.1    Nakajima, M.2    Miyamoto, K.3    Yokoi, T.4
  • 32
    • 72149090100 scopus 로고    scopus 로고
    • Inhibitory effects of polyphenols on human cytochrome p450 3A4 and 2C9 activity
    • Kimura Y, Ito H, Ohnishi R, Hatano T. Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity. Food Chem. Toxicol. 48, 429-435 (2010).
    • (2010) Food Chem. Toxicol. , vol.48 , pp. 429-435
    • Kimura, Y.1    Ito, H.2    Ohnishi, R.3    Hatano, T.4


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