A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-triple quadrupole mass spectrometer

Journal of Chromatography A

Volumn 1217, Issue 44, 2010, Pages 6857-6866

  Dowling, Geraldine ^a   Regan, Liam ^a   Tierney, Julie ^a   Nangle, Michael ^a  

^a Backweston Laboratory Complex   (Ireland)

Author keywords

Drugs of abuse; Human urine; Hybrid liquid chromatography mass spectrometry; Method validation

Indexed keywords

6-MONOACETYLMORPHINE; ANALYTES; ANALYTICAL STRATEGY; BUPRENORPHINE; CALIBRATION CURVES; COLLISION ENERGIES; COMMISSION DECISION 2002/657/EC; DRUG IDENTIFICATION; DRUGS OF ABUSE; FORENSIC LABORATORY; HUMAN URINE; HYBRID LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; ILLICIT DRUG; INFORMATION-DEPENDENT ACQUISITIONS; INTERNAL STANDARDS; IRELAND; KETAMINE; LIBRARY SEARCH; LIGNOCAINE; LINEAR ION TRAP; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; METHOD VALIDATIONS; METHYLENEDIOXYMETHAMPHETAMINE; MORPHINE-3-GLUCURONIDE; MULTIPLE REACTION MONITORING; OPIOIDS; POSITIVE MODE; PRODUCT ION SPECTRA; PSEUDOEPHEDRINE; RAPID METHOD; REGRESSION COEFFICIENT; RUNTIMES; TRIPLE-QUADRUPOLE MASS SPECTROMETER; TRIPLE-QUADRUPOLE MASS SPECTROMETRY; URINE SAMPLE; VALIDATION DATA;

CHROMATOGRAPHY; CRIME; DEUTERIUM; DRUG PRODUCTS; ELECTRON TRAPS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONS; LIQUIDS; MASS SPECTROMETRY; METHANOL; ORGANIC POLYMERS; PATIENT MONITORING;

BODY FLUIDS;

1 BENZYLPIPERAZINE DERIVATIVE; 2 ETHYLIDENE 1,5 DIMETHYL 3,3 DIPHENYLPYRROLIDINE; 3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; AMPHETAMINE; BENZOYLECGONINE; BUPRENORPHINE; COCAINE; CODEINE; DIHYDROCODEINE; HOMOCOCAINE; KETAMINE; LIDOCAINE; METHADONE; METHAMPHETAMINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 ACETATE; OPIATE; PSEUDOEPHEDRINE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG TRAFFIC; EQUIPMENT DESIGN; FORENSIC IDENTIFICATION; HUMAN; HYBRID LIQUID CHROMATOGRAPHY MASS SPECTROMETRY; ION TRAP MASS SPECTROMETRY; IRELAND; MASS SPECTROMETER; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS MONITORING; QUANTITATIVE ANALYSIS; REACTION TIME; STANDARD; URINALYSIS; VALIDATION PROCESS;

AMPHETAMINES; CALIBRATION; CHROMATOGRAPHY, LIQUID; COCAINE; HUMANS; LINEAR MODELS; MASS SPECTROMETRY; METHADONE; MORPHINE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION;

EID: 77957655311     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.08.043     Document Type: Article

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