Polycyclic Aromatic Hydrocarbons

Bioactive Compounds in Foods

Volumn , Issue , 2009, Pages 378-399

  Cano Lerida, Laura ^a   Rose, Martin ^b   Walton, Paul ^c  

^a JOHNSON MATTHEY TECHNOLOGY CENTRE   (United Kingdom)

^b CENTRAL SCIENCE LABORATORY   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Environmental fate and degradation; Health effects and risk assessments; Methods of analysis; Occurrence and mechanism of formation; PAHs in food and dietary intake; PAHs in food, exposure assessment and health effects; Polycyclic aromatic hydrocarbons; Regulations; Sources of PAHs in foods

Indexed keywords

EID: 84889269384     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444302288.ch14     Document Type: Chapter

References (103)

1. Amir, S., Hafidi, M., Merlina, G., Hamdi, H. and Revel, J.C. (2005) Fate of polycyclic aromatic hydrocarbons during composting of lagooning sewage sludge. Chemosphere, 58, 449-458.
2. ATSDR (1995) Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs). Agency for Toxic Substances and Disease Registry, Department of Health and Human Services, Public Health Service, Atlanta, GA.
3. Baird, W.M., Hooven, L.A. and Mahadevan, B. (2005) Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action. Environmental and Molecular Mutagenesis, 45, 106-114.
4. Baran, S., Oleszczuk, P. and Baranowska, E. (2003) Degradation of soil environment in the post-flooding area: Content of polycyclic aromatic hydrocarbons (PAHs) and S-triazine herbicides. Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastes, 38, 799-812.
5. Biernoth, G. and Rost, H.E. (1968) Vorkommen polcyclischer aromatischer Kohlenwasserstoffe in Speiseolen und deren Entfernung. Archiv für Hygiene und Bakteriologie, 152, 238-250.
6. Bigham, S., Medlar, J., Kabir, A., Shende, C., Alli, A. and Malik, A. (2002) Sol-gel capillary microextraction. Analytical Chemistry, 74, 752-761.
7. Booth, P. and Gribben, K. (2005) A review of the formation, environmental fate, and forensic methods for PAHs from aluminum smelting processes. Environmental Forensics, 6, 133-142.
8. Burger, J., Nisbet, I.C.T. and Gochfeld, M. (1992) Metal levels in regrown feathers-assessment of contamination on the wintering and breeding grounds in the same individuals. Journal of Toxicology and Environmental Health, 37, 363-374.
9. Bystol, A.J., Yu, S. and Campiglia, A.D. (2003) Analysis of polycyclic aromatic hydrocarbons in HPLC fractions by laser-excited time-resolved Shpol'skii spectrometry with cryogenic fiber-optic probes. Talanta, 60, 449-458.
10. Chiu, K.H., Yak, H.K., Wai, C.A. and Lang, Q.Y. (2005) Dry ice-originated supercritical and liquid carbon dioxide extraction of organic pollutants from environmental samples. Talanta, 65, 149-154.
11. Chuang, J.C., Pollard, M.A., Chou, Y.L., Menton, R.G. and Wilson, N.K. (1998) Evaluation of enzyme-linked immunosorbent assay for the determination of polycyclic aromatic hydrocarbons in house dust and residential soil. Science of the Total Environment, 224, 189-199.
12. Ciganek, M., Raszyk, J., Kohoutek, J., Ansorgova, A., Salava, J. and Palac, J. (2000) Polycyclic aromatic hydrocarbons (PAHs, nitro-PAHs, oxy-PAHs), polychlorinated biphenyls (PCBs) and organic chlorinated pesticides (OCPs) in the indoor and outdoor air of pig and cattle houses. Veterinarni Medicina, 45, 217-226.
13. Ciganek, M., Ulrich, R., Neca, J. and Raszyk, J. (2002) Exposure of pig fatteners and dairy cows to polycyclic aromatic hydrocarbons. Veterinarni Medicina, 47, 137-142.
14. Costales, M. and Bruya, J. (2005) Discussion of the error associated with polycyclic aromatic hydrocarbon (PAH) analyses. Environmental Forensics, 6, 175-185.
15. Demaneche, S., Meyer, C., Micoud, J., Louwagie, M., Willison, J.C. and Jouanneau, Y. (2004) Identificaion and functional analysis of two aromatic-ring-hydroxylating dioxygenases from a Sphingomonas strain that degrades various polycyclic aromatic hydrocarbons. Applied and Environmental Microbiology, 70, 6714-6725.
16. Dennis, M.J., Massey, R.C., Macweeny, D.J., Knowles, M.E. and Watson, D. (1991) Factors affecting the polycyclic aromatic hydrocarbon content of cereals, fats and other food products. Food Additives and Contaminants, 8, 517-530.
17. Department of Health (1998) 1996 Annual Report of the Committees of Toxicity, Mutagenicity, Carcinogenicity of Chemicals in Food, Consumer Products and the Environment. The Stationery Office. Available from: http://www.archive.officialdocuments.co.uk/document/doh/toxicity/toxic.htm
18. de Vos, R.H., van Dokkum, W., Schouten, A. and de Jong-Berkhout, P. (1990) Polycyclic aromatic hydrocarbons in Dutch total diet samples (1984-1986) Food and Chemical Toxicology, 28, 263-268.
19. Divi, R.L., Beland, F.A., Fu, P.P., Von Tungeln, L.S., Schoket, B., Eltz Camara, J., Ghei, M., Rothman, N., Sinha, R. and Poirier, M.C. (2002) Highly sensitive chemiluminescence immunoassay for benzo[a]pyrene-DNA adducts: Validation by comparison with other methods, and use in human biomonitoring. Carcinogenesis, 23, 2043-2049.
20. Dreij, K., Seidel, A. and Jernstrom, B. (2005) Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo a, l pyrene and benzo alpha pyrene in human cells. Chemical Research in Toxicology, 18, 655-664.
21. Ensing, K. and de Boer, T. (1999) Tailor-made materials for tailor-made applications: Application of molecular imprints in chemical analysis. Trac-Trends in Analytical Chemistry, 18, 138-145.
22. Environmental Protection Agency (1991) Methods for the Determination of Organic Compounds in Drinking Water, EPA 600 ± 4-88 ± 039. US Government Printing Office, Washington, DC.
23. European Commission (2002) Opinion of the Scientific Committee on Food on the Risks to Human Health of Polycyclic Aromatic Hydrocarbons in Food, SCF/CS/CNTM/PAH/29. Peer Consultation Workshop on Approaches to Polycyclic Aromatic Hydrocarbon (Pah) Health Assessment.
24. Fent, K. (2003) Ecotoxicological problems associated with contaminated sites. Toxicology Letters, 140, 353-365.
25. Fisher, M. and Schechter, I. (2000) Encyclopedia of Analytical Chemistry, Polynuclear Aromatic Hydrocarbons Analysis in Environmental Samples. Wiley, Chichester, pp. 3143-3172.
26. Flowers, L., Rieth, S.H., Foureman, G.L., Hertzberg, R., Nesnow, S., Murphy, D.L., Cogliano, V.J., Schoeny, R.S. and Hofmann, E.L. (2002) Health assessment of polycyclic aromatic hydrocarbon mixtures: Current practices and future directions. Polycyclic Aromatic Compounds, 22, 811-821.
27. FSA (2002) Food Survey Information Sheet 31/02 December 2002 PAHs in the UK diet: 2000 total diet study samples. Available from: http://www.food.gov.uk/science/surveillance
28. Gertz, C.H. and Kogelheide, H. (1994) Untersuchung und Beurteilung von PAK in Speisefetten und-olen. Fett-Wissenschaft-Technologie (Fat Science Technology), 96, 175-180.
29. Gorelick, N.J. and Reeder, N.L. (1993) Detection of multiple polycyclic aromatic hydrocarbon DNA adducts by a high-performance liquid-chromatography P-32 postlabeling method. Environmental Health Perspectives, 99, 207-211.
30. Gregory, J., Foster, K., Tyler, H. and Wiseman, M. (1990) Dietary and Nutritional Survey of British Adults. HMSO, London, UK.
31. 2 years. Vol 1: Report of the Diet and Nutrition Survey. HMSO, London, UK.
32. Gregory, J., Lowe, S., Bates, C.J., Prentice, A., Jackson, L.V., Smithers, G., Wenlock, R. and Farron, M. (2000) National Diet and Nutrition Survey: Young People aged 4-18 years. Vol. 1: Report of the Diet and Nutrition Survey. The Stationery Office, London, UK.
33. Guillen, M.D. and Sopelana, P. (2004) Occurrence of polycyclic aromatic hydrocarbons in smoked cheese. Journal of Dairy Science, 87, 556-564.
34. Guillen, M.D. and Sopelana, P. (2005) Headspace solid-phase microextraction as a tool to estimate the contamination of smoked cheeses by polycyclic aromatic hydrocarbons. Journal of Dairy Science, 88, 13-20.
35. Hawthorne, S.B., Grabanski, C.B., Miller, D.J. and Kreitinger, J.P. (2005) Solid-phase microextraction measurement of parent and alkyl polycyclic aromatic hydrocarbons in milliliter sediment pore water samples and determination of K-DOC values. Environmental Science and Technology, 39, 2795-2803.
36. Hennion, M.C. (1999) Solid-phase extraction: Method development, sorbents, and coupling with liquid chromatography. Journal of Chromatography A, 856, 3-54.
37. Hu, Y.L., Yang, Y.Y., Huang, J.X. and Li, G.K. (2005) Preparation and applicaion of poly(dimethylsiloxane)/beta-cyclodextrin solid-phase microextraction membrane. Analytica Chimica Acta, 543, 17-24.
38. IPCS (1998) Selected Non-heterocyclic Polycyclic Aromatic Hydrocarbons. Environmental Health Criteria 202. World Health Organisation, Geneva.
39. Jeffy, B.D., Chirnomas, R.B. and Romagnolo, D.F. (2002) Epigenetics of breast cancer: Polycyclic aromatic hydrocarbons as risk factors. Environmental and Molecular Mutagenesis, 39, 235-244.
40. Jira, W. (2004) A GC/MS method for the determination of carcinogenic polycyclic aromatic hydrocarbons (PAH) in smoked meat products and liquid smokes. European Food Research and Technology, 218, 208-212.
41. Jones, J.M., Anderson, J.W. and Tukey, R.H. (2000) Using the metabolism of PAHs in a human cell line to characterize environmental samples. Environmental Toxicology and Pharmacology, 8, 119-126.
42. Jones, S.H., Chase, M., Sowles, J., Hennigar, P., Landry, N., Wells, P.G., Harding, G.C.H., Krahforst, C. and Brun, L. (2001) Monitoring for toxic contaminants in mytilus edulis from New Hampshire and the Gulf of Maine. Journal of Shellfish Research, 20, 1203-1214.
43. Kanaly, R.A. and Harayama, S. (2000) Biodegradation of high-molecular-weight polycyclic aromatic hydrocarbons by bacteria. Journal of Bacteriology, 182, 2059-2067.
44. Kazerouni, N., Sinha, R., Hsu, C.H., Greenberg, A. and Rothman, N. (2001) Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study. Food and Chemical Toxicology, 39, 423-436.
45. Laor, Y. and Rebhun, M. (2002) Evidence for nonlinear binding of PAHs to dissolved humic acids. Environmental Science and Technology, 36, 955-961.
46. Larsson, B.K., Eriksson, A.T. and Cervenka, M. (1987) Polycyclic aromatic hydrocarbons in crude and deodorizen vegetable oils. Journal of the American Oil Chemists' Society, 64, 365-370.
47. Leonard, S.S., Wang, S., Shi, X.L., Jordan, B.S., Castranova, V. and Dubick, M.A. (2000) Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NF kappa B activation and TNF-alpha release in macrophages. Toxicology, 150, 147-157.
48. Lerario, V.L., Giandomenico, S., Lopez, L. and Cardellicchio, N. (2003) Sources and distribution of polycyclic aromatic hydrocarbons (PAHs) in sediments from the Mar Piccolo of Taranto, Ionian Sea, southern Italy. Annali Di Chimica, 93, 397-406.
49. Li, S., Olegario, R.M., Banyasz, J.L. and Shafer, K.H. (2003) Gas chromatography-mass spectrometry analysis of polycyclic aromatic hydrocarbons in single puff of cigarette smoke. Journal of Analytical and Applied Pyrolysis, 66, 155-163.
50. Librando, V., Tomaselli, G. and Tringali, G. (2005) Optimization of supercritical fluid extraction by carbon dioxide with organic modifiers of polycyclic aromatic hydrocarbons from urban particulate matter. Annali Di Chimica, 95, 211-216.
51. Lodovici, M., Dolara, P., Casalini, C., Ciappellano, S. and Testolini, G. (1995) Polycyclic aromatic hydrocarbon contamination in the Italian diet. Food Additives and Contaminants, 12, 703-713.
52. Mackay, D., Paterso, S. and Shiu, W.Y. (1992) Generic models for evaluating the regional fate of chemicals. Chemosphere 24, 695-717.
53. Mallakin, A., Babu, T.S., Dixon, D.G. and Greenberg, B.M. (2002) Sites of toxicity of specific photooxidation products of anthracene to higher plants: Inhibition of Photosynthetic activity and electron transport in Lemna gibba L. G-3 (duckweed). Environmental Toxicology, 17, 462-471.
54. Manoli, E. and Samara, C. (1999) Polycyclic aromatic hydrocarbons in natural waters: Sources, occurrence and analysis. Trac-Trends in Analytical Chemistry, 18, 417-428.
55. Mastral, A.M., Garcia, T., Lopez, J.M., Murillo, R., Callen, M.S. and Navarro, M.V. (2004) Where are the limits of the gas-phase fluorescence on the polycyclic aromatic compound analysis? Polycyclic Aromatic Compounds, 24, 325-332.
56. Mastrangelo, G., Fadda, E. and Marzia, V. (1996) Polycyclic aromatic hydrocarbons and cancer in man. Environmental Health Perspectives, 104, 1166-1170.
57. Matuszewska, A. and Czaja, M. (2000) The use of synchronous luminescence spectroscopy in qualitative analysis of aromatic fraction of hard coal thermolysis products. Talanta, 52, 457-464.
58. Menichini, E., Bocca, A., Merli, F., Ianni, D. and Monfredini, F. (1991) Polycyclic aromatic hydrocarbons in olive oils on the Italian market. Food Additives and Contaminants, 8, 363-369.
59. Ministry of Agriculture, Fisheries and Food (1994) The British Diet: Finding the Facts 1989-1993. Food Surveillance Paper, 40. HMSO, London, UK.
60. Moret, S. and Conte, L.S. (2000) Polycyclic aromatic hydrocarbons in edible fats and oils: Occurrence and analytical methods. Journal of Chromatography A, 882, 245-253.
61. Moret, S., Dudine, A. and Conte, L.S. (2000) Processing effects on polyaromatic hydrocarbon content of grapeseed oil. Journal of the American Oil Chemists Society, 77, 1289-1292.
62. Mostafa, G.A. (2002) Monitoring of polycyclic aromatic hydrocarbons in seafoods from Lake Timsah. International Journal of Environmental Health Research, 12, 83-91.
63. Mottier, P., Parisod, V. and Turesky, R.J. (2000) Quantitative determination of polycyclic aromatic hydrocarbons in barbecued meat sausages by gas chromatography coupled to mass spectrometry. Journal of Agricultural and Food Chemistry, 48, 1160-1166.
64. Narbonne, J.F., Aarab, N., Clerandeau, C., Daubeze, M., Narbonne, J., Champeau, O. and Garrigues, P. (2005) Scale of classification based on biochemical markers in mussels: Application to pollution monitoring in Mediterranean coasts and temporal trends. Biomarkers, 10, 58-71.
65. O'Connor, T.P. (2002) National distribution of chemical concentrations in mussels and oysters in the USA. Marine Environmental Research, 53, 117-143.
66. Oliferova, L., Statkus, M., Tsysin, G., Shpigun, O. and Zolotov, Y. (2005) On-line solid-phase extraction and HPLC determination of polycyclic aromatic hydrocarbons in water using fluorocarbon polymer sorbents. Analytica Chimica Acta, 538, 35-40.
67. Olson, L.G., Uibel, R.H. and Harris, J.M. (2004) C18-modified metal-colloid substrates for surface-enhanced Raman detection of trace-level polycyclic aromatic hydrocarbons in aqueous solution. Applied Spectroscopy, 58, 1394-1400.
68. Oros, D.R. and Ross, J.R.M. (2005) Polycyclic aromatic hydrocarbons in bivalves from the San Francisco estuary: Spatial distributions, temporal trends, and sources (1993-2001). Marine Environmental Research, 60, 466-488.
69. Ovrebo, S., Haugen, A., Phillips, D.H. and Hewer, A. (1992) Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood-cells from coke-oven workers-correlation with job categories. Cancer Research, 52, 1510-1514.
70. Ovrebo, S., Haugen, A., Fjeldstad, P.E., Hemminki, K. and Szyfter, K. (1994) Biological monitoring of exposure to polycyclic aromatic hydrocarbon in an electrode paste plant. Journal of Occupational and Environmental Medicine, 36, 303-310.
71. Paschke, A., Popp, P. and Schuurmann, G. (1999) Solubility and partitioning studies with polycyclic aromatic hydrocarbons using an optimized SPME procedure. Fresenius Journal of Analytical Chemistry, 363, 426-428.
72. Patel, R., Zhou, R.N., Zinszer, K., Josse, F. and Cernosek, R. (2000) Real-time detection of organic compounds in liquid environments using polymer-coated thickness shear mode quartz resonators. Analytical Chemistry, 72, 4888-4898.
73. Pavanello, S., Favretto, D., Brugnone, F., Mastrangelo, G., Dal Pra, G. and Clonfero, E. (1999) HPLC/fluorescence determination of anti-BPDE-DNA adducts in mononuclear white blood cells from PAH-exposed humans. Carcinogenesis, 20, 431-435.
74. Peattie, M.E., Buss, D.H., Lindsay, D.G. and Smart, G.A. (1983) Reorganisation of the British Total Diet Study for monitoring food constituents from 1981. Food and Chemical Toxicology, 21, 503-507.
75. Phillips, D.H. (1983) 50 Years of benzo(alpha)pyrene. Nature, 303, 468-472.
76. Pufulete, M., Battershill, J., Boobis, A. and Fielder, R. (2004) Approaches to carcinogenic risk assessment for polycyclic aromatic hydrocarbons: A UK perspective. Regulatory Toxicology and Pharmacology, 40, 54-66.
77. Rigou, P., Saini, S. and Setford, S.J. (2004) Field-based supercritical fluid extraction and immunoassay for determination of PAHs in soils. International Journal of Environmental Analytical Chemistry, 84, 979-994.
78. Ritchie, G., Still, K., Rossi, J., III, Bekkedal, M., Bobb, A. and Arfsten, D. (2003) Biological and health effects of exposure to kerosene-based jet fuels and performance additives. Journal of Toxicology and Environmental Health-Part B-Critical Reviews, 6, 357-451.
79. Rizova, V., Nikodinovski, M. and Kendrovski, V. (2005) PAHs-the sources of pollution of the environment and their toxicological impact on human's health. Journal of Environmental Protection and Ecology, 6, 1-7.
80. Rodriguez-Sanmartin, P., Moreda-Pineiro, A., Bermejo-Barrera, A. and Bermejo-Barrera, P. (2005) Ultrasound-assisted solvent extraction of total polycyclic aromatic hydrocarbons from mussels followed by spectrofluorimetric determination. Talanta, 66, 683-690.
81. Roy, G., Vuillemin, R. and Guyomarch, J. (2005) On-site determination of polynuclear aromatic hydrocarbons in seawater by stir bar sorptive extraction (SBSE) and thermal desorption GC-MS. Talanta, 66, 540-546.
82. Sagredos, A.N., Sinha-Roy, D. and Thomas, A. (1988) The determination, occurrence and composition of polycyclic aromatic hydrocarbons in oils and fats. Fett-Wissenschaft-Technologie (Fat Science Technology), 90, 76-81.
83. Schaum, J., Schuda, L., Wu, C., Sears, R., Ferrario, J. and Andrews, K. (2003) A national survey of persistent, bioaccumulative, and toxic (PBT) pollutants in the United States milk supply. Journal of Exposure Analysis and Environmental Epidemiology, 13, 177-186.
84. Schneider, U.A., Brown, M.M. and Logan, R.A. (1995) Screening assay for dioxin-like compounds based on competitive-binding to the murine hepatic Ah receptor 1. Assay development. Environmental Science and Technology, 29, 2595-2602.
85. Siddiqi, M.A., Yuan, Z.X. and Honey, S.A. (2002) Metabolism of PAHs and methyl-substituted PAHs by sphingomonas paucimobilis strain EPA 505. Polycyclic Aromatic Compounds, 22, 3-4.
86. Sluszny, C., Gridin, V.V., Bulatov, V. and Schechter, I. (2002) Analysis of polycyclic aromatic hydrocarbons in heterogeneous samples. Reviews in Analytical Chemistry, 21, 77-165.
87. Sluszny, C., Gridin, V.V., Bulatov, V. and Schechter, I. (2004) Polymer film sensor for sampling and remote analysis of polycyclic aromatic hydrocarbons in clear and turbid aqueous environments. Analytica Chimica Acta, 522, 145-152.
88. Smith, B.W. and Hurtubise, R.J. (2004) New methodology for the characterization of (+/-)-anti-BPDE-DNA adducts an tetrol I-1 with solid-matrix phosphorescence. Analytica Chimica Acta, 502, 149-159.
89. Speer, K., Steeg, E., Horstmann, P., Kühn, T.H. and Montag, A. (1990) Determination and distribution of polycyclic aromatic hydrocarbons in native vegetable oils, smoked fish products, mussels and oysters, and bream from the River Elbe. Journal of High Resolution Chromatography and Chromatography, 13, 104-111.
90. Stolyhwo, A. and Sikorski, Z.E. (2005) Polycyclic aromatic hydrocarbons in smoked fish-a critical review. Food Chemistry, 91, 303-311.
91. Storelli, M.M. and Marcotrigiano, G.O. (2001) Polycyclic aromatic hydrocarbons in mussels (Mytilus gallo-provincialis) form the Ionian Sea, Italy. Journal of Food Protection, 64, 405-409.
92. Swetman, A., Head, S. and Evans, D. (1999) Contamination of coconut oil by PAH. Inform, 10, 706-712.
93. Tamakawa, K. (2004) Handbook of Food Analysis: Food Science and Technology. Vol. 2. (ed. L. Nollet). Marcel Dekker, Inc., New York, pp. 138.
94. Ter Laak, T.L., Mayer, P., Busser, F.J.M., Klamer, H.J.C. and Hermens, J.L.M. (2005) Sediment dilution method to determine sorption coefficients of hydrophobic organic chemicals. Environmental Science & Technology, 39, 4220-4225.
95. Thurman, E.M. and Mills, M.S. (1998) Solid-Phase Extraction: Principles and Practice. Wiley/Interscience, New York, 372 pp.
96. Tiscornia, E., Forina, M. and Evangelisti, F. (1982) Composizione chimica dell'olio di oliva e sue variazioni indotte dal processo di rettificazione. La Rivista Italiana delle Sostanze Grasse, 59, 519-556.
97. U.S. Environmental Protection Agency (2002) O. O. R. A. D., National Center for Environmental Assessment, Washington Office, Washington, DC.
98. Wani, M.A., El-Mahdy, M.A., Hamada, F.M., Wani, G., Zhu, Q., Wang, Q. and Wani, A.A. (2002) Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21waf1/cip1 and pRb. Mutation Research, 505, 13-25.
99. Weisshoff, H., Preiss, A., Nehls, I., Win, T. and Mugge, C. (2002) Development of an HPLC-NMR method for the determination of PAHs in soil samples-a comparison with conventional methods. Analytical and Bioanalytical Chemistry, 373, 810-819.
100. Wenzl, T., Simon, R., Kleiner, J. and Anklam, E. (2006) Analytical methods for polycyclic aromatic hydrocarbons (PAHs) in food and the environment needed for new food legislation in the European Union. Trends in Analytical Chemistry, 25, 716-725.
101. Wootton, E.C., Dyrynda, E.A., Pipe, R.K. and Ratcliffe, N.A. (2003) Comparisons of PAH-induced im-munomodulation in three bivalve molluscs. Aquatic Toxicology, 65, 13-25.
102. Zabiegala, B., Kot, A. and Namiesnik, J. (2000) Long-term monitoring of organic pollutants in water-application of passive dosimetry. Chemia Analityczna, 45, 645-657.
103. Zmirou, D., Masclet, P., Boudet, C., Dor, F. and Dechenaux, J. (2000) Personal exposure to atmospheric polycyclic aromatic hydrocarbons in a general adult population and lung cancer risk assessment. Journal of Occupational and Environmental Medicine, 42, 121-126.