Retinal pigment epithelial cells express a functional receptor for glucagon-like peptide-1 (GLP-1)

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Puddu, Alessandra ^a   Sanguineti, Roberta ^a   Montecucco, Fabrizio ^b,c   Viviani, Giorgio L ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; VASCULOTROPIN A; ENZYME INHIBITOR; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; VEGFA PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; CELL LINE; CELL SURVIVAL; CYTOLOGY; GENE SILENCING; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME;

CELL LINE; CELL SURVIVAL; ENZYME INHIBITORS; GENE SILENCING; GLUCAGON-LIKE PEPTIDE 1; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, GLUCAGON; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84889026586     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/975032     Document Type: Article

References (38)

1. Holst J. J., The physiology of glucagon-like peptide 1. Physiological Reviews 2007 87 4 1409 1439 2-s2.0-35748957503 10.1152/physrev.00034.2006 (Pubitemid 350041474)
2. Baggio L. L., Drucker D. J., Biology of Incretins: GLP-1 and GIP. Gastroenterology 2007 132 6 2131 2157 2-s2.0-34248223285 10.1053/j.gastro.2007. 03.054 (Pubitemid 46711096)
3. Puddu A., Storace D., Durante A., Odetti P., Viviani G. L., Glucagon-like peptide-1 counteracts the detrimental effects of advanced glycation end-products in the pancreatic beta cell line HIT-T 15. Biochemical and Biophysical Research Communications 2010 398 3 462 466 2-s2.0-77955273235 10.1016/j.bbrc.2010.06.100
4. Puddu A., Mach F., Nencioni A., Viviani G. L., Montecucco F., An emerging role of glucagon-like peptide-1 in preventing advanced-glycation-end-product- mediated damages in diabetes. Mediators of Inflammation 2013 2013 9 10.1155/2013/591056 591056
5. Wajchenberg B. L., Clinical approaches to preserve β -cell function in diabetes. Advances in Experimental Medicine and Biology 2010 654 515 535 2-s2.0-77953931504 10.1007/978-90-481-3271-3-23
6. Vilsboll T., The effects of glucagon-like peptide-1 on the beta cell. Diabetes, Obesity and Metabolism 2009 11 supplement 3 11 18
7. Urusova I. A., Farilla L., Hui H., D'Amico E., Perfetti R., GLP-1 inhibition of pancreatic islet cell apoptosis. Trends in Endocrinology and Metabolism 2004 15 1 27 33 2-s2.0-1042278911 10.1016/j.tem.2003.11.006 (Pubitemid 38198096)
8. Thorens B., Expression cloning of the pancreatic β cell receptor for the gluco- incretin hormone glucagon-like peptide 1. Proceedings of the National Academy of Sciences of the United States of America 1992 89 18 8641 8645 2-s2.0-0026775150
9. Doyle M. E., Egan J. M., Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacology and Therapeutics 2007 113 3 546 593 2-s2.0-33847617011 10.1016/j.pharmthera.2006.11.007 (Pubitemid 46365961)
10. Quoyer J., Longuet C., Broca C., Linck N., Costes S., Varin E., Bockaert J. L., Bertrand G., Dalle S., GLP-1 mediates antiapoptotic effect by phosphorylating bad through a β -arrestin 1-mediated ERK1/2 activation in pancreatic β -cells. Journal of Biological Chemistry 2010 285 3 1989 2002 2-s2.0-76249122645 10.1074/jbc.M109.067207
11. Montrose-Rafizadeh C., Avdonin P., Garant M. J., Rodgers B. D., Kole S., Yang H., Levine M. A., Schwindinger W., Bernier M., Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells. Endocrinology 1999 140 3 1132 1140 2-s2.0-0032941026 (Pubitemid 29104213)
12. Drucker D. J., Nauck M. A., The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. The Lancet 2006 368 9548 1696 1705 2-s2.0-33846006173 10.1016/S0140-6736(06)69705-5 (Pubitemid 46048557)
13. Fu Z., Kuang H. Y., Hao M., Gao X. Y., Liu Y., Shao N., Protection of exenatide for retinal ganglion cells with different glucose concentrations. Peptides 2011 37 25 31
14. Zhang Y., Wang Q., Zhang J., Lei X., Xu G. T., Ye W., Protection of exendin-4 analogue in early experimental diabetic retinopathy. Graefe's Archive for Clinical and Experimental Ophthalmology 2009 247 5 699 706 2-s2.0-64449087059 10.1007/s00417-008-1004-3
15. Zhang Y., Zhang J., Wang Q., Lei X., Chu Q., Xu G.-T., Ye W., Intravitreal injection of exendin-4 analogue protects retinal cells in early diabetic rats. Investigative Ophthalmology and Visual Science 2011 52 1 278 285 2-s2.0-79952230999 10.1167/iovs.09-4727
16. Antonetti D. A., Barber A. J., Bronson S. K., Freeman W. M., Gardner T. W., Jefferson L. S., Kester M., Kimball S. R., Krady J. K., LaNoue K. F., Norbury C. C., Quinn P. G., Sandirasegarane L., Simpson I. A., Diabetic retinopathy: Seeing beyond glucose-induced microvascular disease. Diabetes 2006 55 9 2401 2411 2-s2.0-33750597534 10.2337/db05-1635 (Pubitemid 44871140)
17. Gardner T. W., Antonetti D. A., Barber A. J., LaNoue K. F., Levison S. W., Diabetic retinopathy: more than meets the eye. Survey of Ophthalmology 2002 47 supplement 2 S253 S262 2-s2.0-0036943831 10.1016/S0039-6257(02)00387-9 (Pubitemid 36351245)
18. Zhang J., Wu Y., Jin Y., Ji F., Sinclair S. H., Luo Y., Xu G., Lu L., Dai W., Yanoff M., Li W., Xu G.-T., Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes. Investigative Ophthalmology and Visual Science 2008 49 2 732 742 2-s2.0-40649087674 10.1167/iovs.07-0721
19. Bok D., The retinal pigment epithelium: a versatile partner in vision. Journal of Cell Science 1993 17 189 195 2-s2.0-0027741818 (Pubitemid 24041298)
20. Strauss O., The retinal pigment epithelium in visual function. Physiological Reviews 2005 85 3 845 881 2-s2.0-21244451958 10.1152/physrev. 00021.2004 (Pubitemid 40885218)
21. Buteau J., Roduit R., Susini S., Prentki M., Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells. Diabetologia 1999 42 7 856 864 2-s2.0-0032768616 10.1007/s001250051238 (Pubitemid 29325077)
22. Adams N. R., Pathological changes in the tissues of infertile ewes with clover disease. Journal of Comparative Pathology 1976 86 1 29 35 2-s2.0-0017105382
23. Luciano Viviani G., Puddu A., Sacchi G., Garuti A., Storace D., Durante A., Monacelli F., Odetti P., Glycated fetal calf serum affects the viability of an insulin-secreting cell line in vitro. Metabolism 2008 57 2 163 169 2-s2.0-38049144209 10.1016/j.metabol.2007.08.020
24. Hemmings B. A., Restuccia D. F., PI3K-PKB/Akt pathway, cold spring harb. Perspectives in Biology and Medicine 2012 4 a011189
25. Buteau J., Foisy S., Joly E., Prentki M., Glucagon-like peptide 1 induces pancreatic β -cell proliferation via transactivation of the epidermal growth factor receptor. Diabetes 2003 52 1 124 132 2-s2.0-0037221488 10.2337/diabetes.52.1.124 (Pubitemid 36042116)
26. Kimura R., Okouchi M., Kato T., Imaeda K., Okayama N., Asai K., Joh T., Epidermal growth factor receptor transactivation is necessary for glucagon-like Peptide-1 to protect PC12 cells from apoptosis. Neuroendocrinology 2013 97 300 308
27. Kvanta A., Expression and regulation of vascular endothelial growth factor in choroidal fibroblasts. Current Eye Research 1995 14 11 1015 1020 2-s2.0-0028883542
28. Foxton R. H., Finkelstein A., Vijay S., Dahlmann-Noor A., Khaw P. T., Morgan J. E., Shima D. T., Ng Y. S., VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma. The American Journal of Pathology 2013 182 1379 1390
29. Simó R., Villarroel M., Corraliza L., Hernández C., Garcia-Ramírez M., The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier-implications for the pathogenesis of diabetic retinopathy. Journal of Biomedicine and Biotechnology 2010 2010 15 2-s2.0-77953170750 10.1155/2010/190724 190724
30. + channels in pancreatic beta cells: role, regulation and potential as therapeutic targets. Diabetologia 2003 46 8 1046 1062 2-s2.0-0042879894 10.1007/s00125-003-1159-8 (Pubitemid 37041235)
31. Rafiq I., da Silva Xavier G., Hooper S., Rutter G. A., Glucose-stimulated preproinsulin gene expression and nuclear trans- location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. Journal of Biological Chemistry 2000 275 21 15977 15984 2-s2.0-0034717337 10.1074/jbc.275.21.15977 (Pubitemid 30366902)
32. Trumper K., Trumper A., Trusheim H., Arnold R., Goke B., Horsch D., Integrative mitogenic role of protein kinase B/Akt in beta-cells. Annals of the New York Academy of Sciences 2000 921 242 250 (Pubitemid 32094549)
33. Bernal-Mizrachi E., Wen W., Stahlhut S., Welling C. M., Permutt M. A., Islet β cell expression of constitutively active Akt1/PKB α induces striking hypertrophy, hyperplasia, and hyperinsulinemia. Journal of Clinical Investigation 2001 108 11 1631 1638 2-s2.0-0035210374 10.1172/JCI200113785 (Pubitemid 33144873)
34. Tuttle R. L., Gill N. S., Pugh W., Lee J.-P., Koeberlein B., Furth E. E., Polonsky K. S., Naji A., Birnbaum M. J., Regulation of pancreatic β -cell growth and survival by the serine/threonine protein kinase Akt1/PKB α Nature Medicine 2001 7 10 1133 1137 2-s2.0-0034781057 10.1038/nm1001-1133 (Pubitemid 33010022)
35. Arnette D., Gibson T. B., Lawrence M. C., January B., Khoo S., McGlynn K., Vanderbilt C. A., Cobb M. H., Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic β cells. Journal of Biological Chemistry 2003 278 35 32517 32525 2-s2.0-0041375468 10.1074/jbc.M301174200 (Pubitemid 37055689)
36. + influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic β -cells. Journal of Biological Chemistry 2002 277 50 48146 48151 2-s2.0-0037073717 10.1074/jbc.M209165200 (Pubitemid 35470763)
37. Puddu A., Sanguineti R., Mach F., Dallegri F., Viviani G. L., Montecucco F., Update on the protective molecular pathways improving pancreatic Beta-cell dysfunction. Mediators of Inflammation 2013 2013 14 10.1155/2013/750540 750540
38. Harikumar K. G., Wootten D., Pinon D. I., Koole C., Ball A. M., Furness S. G., Graham B., Dong M., Christopoulos A., Miller L. J., Sexton P. M., Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery. Proceedings of the National Academy of Sciences of the United States of America 2012 109 18607 18612