메뉴 건너뛰기




Volumn 97, Issue 4, 2013, Pages 300-308

Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis

Author keywords

Apoptosis; EGF transactivation; G protein coupled receptor; Glucagon like peptide 1; Methylglyoxal; PC12 cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCAGON LIKE PEPTIDE 1; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84879148073     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000345529     Document Type: Article
Times cited : (23)

References (54)
  • 1
    • 3543067962 scopus 로고    scopus 로고
    • Neurodegenerative disorders associated with diabetes mellitus
    • Ristow M: Neurodegenerative disorders associated with diabetes mellitus. J Mol Med 2004; 82: 510-529.
    • (2004) J Mol Med , vol.82 , pp. 510-529
    • Ristow, M.1
  • 2
    • 0029012763 scopus 로고
    • Incidence and risk factors of vascular dementia and alzheimer's disease in a defined elderly japanese population: The hisayama study
    • Yoshitake T, Kiyohara Y, Kato I, Ohmura T, Iwamoto H, Nakayama K, Ohmori S, Nomiyama K, Kawano H, Ueda K, et al: Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study. Neurology 1995; 45: 1161-1168.
    • (1995) Neurology , vol.45 , pp. 1161-1168
    • Yoshitake, T.1    Kiyohara, Y.2    Kato, I.3    Ohmura, T.4    Iwamoto, H.5    Nakayama, K.6    Ohmori, S.7    Nomiyama, K.8    Kawano, H.9    Ueda, K.10
  • 4
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of alzheimer disease and decline in cognitive function
    • Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA: Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004; 61: 661-666.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 6
    • 0038248960 scopus 로고    scopus 로고
    • Glucagonlike peptide-1 decreases endogenous amyloid-peptide (a) levels and protects hippocampal neurons from death induced by a and iron
    • Perry T, Lahiri DK, Sambamurti K, Chen D, Mattson MP, Egan JM, Greig NH: Glucagonlike peptide-1 decreases endogenous amyloid-peptide (A levels and protects hippocampal neurons from death induced by A and iron. J Neurosci Res 2003; 72: 603-612.
    • (2003) J Neurosci Res , vol.72 , pp. 603-612
    • Perry, T.1    Lahiri, D.K.2    Sambamurti, K.3    Chen, D.4    Mattson, M.P.5    Egan, J.M.6    Greig, N.H.7
  • 7
    • 22144491473 scopus 로고    scopus 로고
    • Enhancing central nervous system endogenous glp-1 receptor pathways for intervention in alzheimer's disease
    • Perry T, Greig NH: Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease. Curr Alzheimer Res 2005; 2: 377-385.
    • (2005) Curr Alzheimer Res , vol.2 , pp. 377-385
    • Perry, T.1    Greig, N.H.2
  • 9
    • 0032756827 scopus 로고    scopus 로고
    • Immunocytochemical evidence for a paracrine interaction between gip and glp-1-producing cells in canine small intestine
    • Damholt AB, Kofod H, Buchan AM: Immunocytochemical evidence for a paracrine interaction between GIP and GLP-1-producing cells in canine small intestine. Cell Tissue Res 1999; 298: 287-293.
    • (1999) Cell Tissue Res , vol.298 , pp. 287-293
    • Damholt, A.B.1    Kofod, H.2    Buchan, A.M.3
  • 10
    • 0035827528 scopus 로고    scopus 로고
    • Src and pyk2 mediate g-protein-coupled receptor activation of epidermal growth factor receptor but are not required for coupling to the mitogen-Activated protein kinase signaling cascade
    • Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, Okigaki M, Cary LA, Moolenaar WH, Schlessinger J: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor but are not required for coupling to the mitogen-Activated protein kinase signaling cascade. J Biol Chem 2001; 276: 20130-20135.
    • (2001) J Biol Chem , vol.276 , pp. 20130-20135
    • Andreev, J.1    Galisteo, M.L.2    Kranenburg, O.3    Logan, S.K.4    Chiu, E.S.5    Okigaki, M.6    Cary, L.A.7    Moolenaar, W.H.8    Schlessinger, J.9
  • 11
    • 0037784011 scopus 로고    scopus 로고
    • Glp-1 and gip are colocalized in a subset of endocrine cells in the small intestine
    • Mortensen K, Christensen LL, Holst JJ, Orskov C: GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul Pept 2003; 114: 189-196.
    • (2003) Regul Pept , vol.114 , pp. 189-196
    • Mortensen, K.1    Christensen, L.L.2    Holst, J.J.3    Orskov, C.4
  • 12
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 with the bloodbrain barrier
    • Kastin AJ, Akerstrom V, Pan W: Interactions of glucagon-like peptide-1 with the bloodbrain barrier. J Mol Neurosci 2002; 18: 7-14.
    • (2002) J Mol Neurosci , vol.18 , pp. 7-14
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 13
    • 0028325376 scopus 로고
    • Divergent tissue-specific and developmental expression of receptors for glucagon and glucagonlike peptide-1 in the mouse
    • Campos RV, Lee YC, Drucker DJ: Divergent tissue-specific and developmental expression of receptors for glucagon and glucagonlike peptide-1 in the mouse. Endocrinology 1994; 134: 2156-2164.
    • (1994) Endocrinology , vol.134 , pp. 2156-2164
    • Campos, R.V.1    Lee, Y.C.2    Drucker, D.J.3
  • 14
    • 0028814666 scopus 로고
    • Structural characterization by affinity cross-linking of glucagon-like peptide-1 ( 7-36) amide receptor in rat brain
    • Calvo JC, Yusta B, Mora F, Blazquez E: Structural characterization by affinity cross-linking of glucagon-like peptide-1 (7-36) amide receptor in rat brain. J Neurochem 1995; 64: 299-306.
    • (1995) J Neurochem , vol.64 , pp. 299-306
    • Calvo, J.C.1    Yusta, B.2    Mora, F.3    Blazquez, E.4
  • 15
    • 0028867442 scopus 로고
    • Distribution of glp-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain glp-1 binding sites
    • Goke R, Larsen PJ, Mikkelsen JD, Sheikh SP: Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995; 7: 2294-2300.
    • (1995) Eur J Neurosci , vol.7 , pp. 2294-2300
    • Goke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 16
    • 34848901678 scopus 로고    scopus 로고
    • Geniposide, a novel agonist for glp-1 receptor, prevents pc12 cells from oxidative damage via map kinase pathway
    • Liu J, Yin F, Zheng X, Jing J, Hu Y: Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway. Neurochem Int 2007; 51: 361-369.
    • (2007) Neurochem Int , vol.51 , pp. 361-369
    • Liu, J.1    Yin, F.2    Zheng, X.3    Jing, J.4    Hu, Y.5
  • 17
    • 52249112474 scopus 로고    scopus 로고
    • Mutated recombinant human glucagon-like peptide-1 protects sh-sy5y cells from apoptosis induced by amyloid-peptide ( 1-42)
    • Qin Z, Sun Z, Huang J, Hu Y, Wu Z, Mei B: Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-peptide (1-42). Neurosci Lett 2008; 444: 217-221.
    • (2008) Neurosci Lett , vol.444 , pp. 217-221
    • Qin, Z.1    Sun, Z.2    Huang, J.3    Hu, Y.4    Wu, Z.5    Mei, B.6
  • 19
    • 1342323632 scopus 로고    scopus 로고
    • Erbb receptors: Directing key signaling networks throughout life
    • Holbro T, Hynes NE: ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 2004; 44: 195-217.
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 20
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the egf receptor in signalling by g-protein-coupled receptors
    • Daub H, Weiss FU, Wallasch C, Ullrich A: Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996; 379: 557-560.
    • (1996) Nature , vol.379 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ullrich, A.4
  • 21
    • 0035952656 scopus 로고    scopus 로고
    • Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission
    • Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A: Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 2001; 20: 1594-1600.
    • (2001) Oncogene , vol.20 , pp. 1594-1600
    • Gschwind, A.1    Zwick, E.2    Prenzel, N.3    Leserer, M.4    Ullrich, A.5
  • 22
    • 0036378574 scopus 로고    scopus 로고
    • Structure-function of the glucagon receptor family of gprotein-coupled receptors: The glucagon, gip, glp-1, and glp-2 receptors
    • Brubaker PL, Drucker DJ: Structure-function of the glucagon receptor family of Gprotein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors. Receptors Channels 2002; 8: 179-188.
    • (2002) Receptors Channels , vol.8 , pp. 179-188
    • Brubaker, P.L.1    Drucker, D.J.2
  • 23
    • 0030770603 scopus 로고    scopus 로고
    • Critical role of calcium-dependent epidermal growth factor receptor transactivation in pc12 cell membrane depolarization and bradykinin signaling
    • Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, Ullrich A: Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem 1997; 272: 24767-24770.
    • (1997) J Biol Chem , vol.272 , pp. 24767-24770
    • Zwick, E.1    Daub, H.2    Aoki, N.3    Yamaguchi-Aoki, Y.4    Tinhofer, I.5    Maly, K.6    Ullrich, A.7
  • 25
    • 0030837027 scopus 로고    scopus 로고
    • The m1 muscarinic acetylcholine receptor transactivates the egf receptor to modulate ion channel activity
    • Tsai W, Morielli AD, Peralta EG: The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity. EMBO J 1997; 16: 4597-4605.
    • (1997) EMBO J , vol.16 , pp. 4597-4605
    • Tsai, W.1    Morielli, A.D.2    Peralta, E.G.3
  • 26
    • 0345258507 scopus 로고    scopus 로고
    • Activation of tyrosine kinases by reactive oxygen species in vascular smooth muscle cells: Significance and involvement of egf receptor transactivation by angiotensin ii
    • Frank GD, Eguchi S: Activation of tyrosine kinases by reactive oxygen species in vascular smooth muscle cells: significance and involvement of EGF receptor transactivation by angiotensin II. Antioxid Redox Signal 2003; 5: 771-780.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 771-780
    • Frank, G.D.1    Eguchi, S.2
  • 27
    • 0037371354 scopus 로고    scopus 로고
    • Distinct mechanisms of receptor and non-receptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: Role of metalloprotease and protein kinase c
    • Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, Eguchi S: Distinct mechanisms of receptor and non-receptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-. Mol Cell Biol 2003; 23: 1581-1589.
    • (2003) Mol Cell Biol , vol.23 , pp. 1581-1589
    • Frank, G.D.1    Mifune, M.2    Inagami, T.3    Ohba, M.4    Sasaki, T.5    Higashiyama, S.6    Dempsey, P.J.7    Eguchi, S.8
  • 28
    • 0030614911 scopus 로고    scopus 로고
    • G subunits mediate src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for g-protein-coupled receptor-mediated ras activation
    • Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK, Lefkowitz RJ: G subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G-protein-coupled receptor-mediated Ras activation. J Biol Chem 1997; 272: 4637-4644.
    • (1997) J Biol Chem , vol.272 , pp. 4637-4644
    • Luttrell, L.M.1    Della Rocca, G.J.2    Van Biesen, T.3    Luttrell, D.K.4    Lefkowitz, R.J.5
  • 29
    • 0033599039 scopus 로고    scopus 로고
    • Egf receptor transactivation by g-protein-coupled receptors requires metalloproteinase cleavage of prohb-egf
    • Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A: EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999; 402: 884-888.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 30
    • 0035896502 scopus 로고    scopus 로고
    • Activation of mapks by angiotensin ii in vascular smooth muscle cells. Metalloprotease-dependent egf receptor activation is required for activation of erk and p38 mapk but not for jnk
    • Eguchi S, Dempsey PJ, Frank GD, Motley ED, Inagami T: Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK. J Biol Chem 2001; 276: 7957-7962.
    • (2001) J Biol Chem , vol.276 , pp. 7957-7962
    • Eguchi, S.1    Dempsey, P.J.2    Frank, G.D.3    Motley, E.D.4    Inagami, T.5
  • 31
    • 0346245840 scopus 로고    scopus 로고
    • Emerging roles of tace as a key protease in erbb ligand shedding
    • Dempsey PJ, Garton K, Raines EW: Emerging roles of TACE as a key protease in ErbB ligand shedding. Mol Interv 2002; 2: 136-141.
    • (2002) Mol Interv , vol.2 , pp. 136-141
    • Dempsey, P.J.1    Garton, K.2    Raines, E.W.3
  • 33
    • 0032527705 scopus 로고    scopus 로고
    • The cellular response to oxidative stress: Influences of mitogen-Activated protein kinase signalling pathways on cell survival
    • Wang X, Martindale JL, Liu Y, Holbrook NJ: The cellular response to oxidative stress: influences of mitogen-Activated protein kinase signalling pathways on cell survival. Biochem J 1998; 333: 291-300.
    • (1998) Biochem J , vol.333 , pp. 291-300
    • Wang, X.1    Martindale, J.L.2    Liu, Y.3    Holbrook, N.J.4
  • 34
    • 84916265276 scopus 로고
    • Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal
    • Cohen S: Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J Biol Chem 1962; 237: 1555-1562.
    • (1962) J Biol Chem , vol.237 , pp. 1555-1562
    • Cohen, S.1
  • 35
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by macrophage-like cells that is related to egf
    • Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M: A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991; 251: 936-939.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsbrun, M.5
  • 36
    • 0024593476 scopus 로고
    • Structure and function of human amphiregulin: A member of the epidermal growth factor family
    • Shoyab M, Plowman GD, McDonald VL, Bradley JG, Todaro GJ: Structure and function of human amphiregulin: a member of the epidermal growth factor family. Science 1989; 243: 1074-1076.
    • (1989) Science , vol.243 , pp. 1074-1076
    • Shoyab, M.1    Plowman, G.D.2    McDonald, V.L.3    Bradley, J.G.4    Todaro, G.J.5
  • 37
    • 0021752924 scopus 로고
    • Human transforming growth factor: Precursor structure and expression in e. Coli
    • Derynck R, Roberts AB, Winkler ME, Chen EY, Goeddel DV: Human transforming growth factor-: precursor structure and expression in E. coli . Cell 1984; 38: 287-297.
    • (1984) Cell , vol.38 , pp. 287-297
    • Derynck, R.1    Roberts, A.B.2    Winkler, M.E.3    Chen, E.Y.4    Goeddel, D.V.5
  • 39
    • 0028937620 scopus 로고
    • Epiregulin. A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes
    • Toyoda H, Komurasaki T, Uchida D, Takayama Y, Isobe T, Okuyama T, Hanada K: Epiregulin. A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes. J Biol Chem 1995; 270: 7495-7500.
    • (1995) J Biol Chem , vol.270 , pp. 7495-7500
    • Toyoda, H.1    Komurasaki, T.2    Uchida, D.3    Takayama, Y.4    Isobe, T.5    Okuyama, T.6    Hanada, K.7
  • 40
    • 0035947578 scopus 로고    scopus 로고
    • Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily
    • Strachan L, Murison JG, Prestidge RL, Sleeman MA, Watson JD, Kumble KD: Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily. J Biol Chem 2001; 276: 18265-18271.
    • (2001) J Biol Chem , vol.276 , pp. 18265-18271
    • Strachan, L.1    Murison, J.G.2    Prestidge, R.L.3    Sleeman, M.A.4    Watson, J.D.5    Kumble, K.D.6
  • 41
    • 0032915392 scopus 로고    scopus 로고
    • Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
    • Hackel PO, Zwick E, Prenzel N, Ullrich A: Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 1999; 11: 184-189.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 184-189
    • Hackel, P.O.1    Zwick, E.2    Prenzel, N.3    Ullrich, A.4
  • 42
    • 0032939325 scopus 로고    scopus 로고
    • Multiple positive and negative regulators of signaling by the egf-receptor
    • Moghal N, Sternberg PW: Multiple positive and negative regulators of signaling by the EGF-receptor. Curr Opin Cell Biol 1999; 11: 190-196.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 190-196
    • Moghal, N.1    Sternberg, P.W.2
  • 45
    • 0037221488 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 induces pancreatic cell proliferation via transactivation of the epidermal growth factor receptor
    • Buteau J, Foisy S, Joly E, Prentki M: Glucagon-like peptide 1 induces pancreatic cell proliferation via transactivation of the epidermal growth factor receptor. Diabetes 2003; 52: 124-132.
    • (2003) Diabetes , vol.52 , pp. 124-132
    • Buteau, J.1    Foisy, S.2    Joly, E.3    Prentki, M.4
  • 47
    • 0000912287 scopus 로고    scopus 로고
    • Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia-And free radical-induced injuries
    • Peng H, Wen TC, Tanaka J, Maeda N, Matsuda S, Desaki J, Sudo S, Zhang B, Sakanaka M: Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia-And free radical-induced injuries. J Cereb Blood Flow Metab 1998; 18: 349-360.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 349-360
    • Peng, H.1    Wen, T.C.2    Tanaka, J.3    Maeda, N.4    Matsuda, S.5    Desaki, J.6    Sudo, S.7    Zhang, B.8    Sakanaka, M.9
  • 48
    • 0346037347 scopus 로고    scopus 로고
    • Cyclic amp induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of map kinase, akt, and neurite outgrowth in pc12 cells
    • Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Muller-Esterl W, Zeuzem S: Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. J Biol Chem 2002; 277: 43623-43630.
    • (2002) J Biol Chem , vol.277 , pp. 43623-43630
    • Piiper, A.1    Dikic, I.2    Lutz, M.P.3    Leser, J.4    Kronenberger, B.5    Elez, R.6    Cramer, H.7    Muller-Esterl, W.8    Zeuzem, S.9
  • 49
    • 33745714456 scopus 로고    scopus 로고
    • Adams as mediators of egf receptor transactivation by g-protein-coupled receptors
    • Ohtsu H, Dempsey PJ, Eguchi S: ADAMs as mediators of EGF receptor transactivation by G-protein-coupled receptors. Am J Physiol Cell Physiol 2006; 291:C1-C10.
    • (2006) Am J Physiol Cell Physiol , vol.291 , pp. C1-C10
    • Ohtsu, H.1    Dempsey, P.J.2    Eguchi, S.3
  • 51
    • 0036289647 scopus 로고    scopus 로고
    • Metalloprotease inhibitor blocks angiotensin iiinduced migration through inhibition of epidermal growth factor receptor transactivation
    • Saito S, Frank GD, Motley ED, Dempsey PJ, Utsunomiya H, Inagami T, Eguchi S: Metalloprotease inhibitor blocks angiotensin IIinduced migration through inhibition of epidermal growth factor receptor transactivation. Biochem Biophys Res Commun 2002; 294: 1023-1029.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 1023-1029
    • Saito, S.1    Frank, G.D.2    Motley, E.D.3    Dempsey, P.J.4    Utsunomiya, H.5    Inagami, T.6    Eguchi, S.7
  • 53
    • 79952575223 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor is a potent neurotrophic factor for pc12 cells
    • Zhou Y, Besner GE: Heparin-binding epidermal growth factor-like growth factor is a potent neurotrophic factor for PC12 cells. Neurosignals 2010; 18: 141-151.
    • (2010) Neurosignals , vol.18 , pp. 141-151
    • Zhou, Y.1    Besner, G.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.