Novel recombinant human lactoferrin: Differential activation of oxidative stress related gene expression

Journal of Biotechnology

Volumn 168, Issue 4, 2013, Pages 666-675

  Kruzel, Marian L ^a   Actor, Jeffrey K ^b   Zimecki, Michał ^d   Wise, Jasen ^e   Płoszaj, Paulina ^b,h   Mirza, Shaper ^c   Kruzel, Mark ^b   Hwang, Shen An ^b   Ba, Xueqing ^f,g   Boldogh, Istvan ^f  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^d INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^e QIAGEN   (United States)

^f University of Texas Medical Branch School of Medicine   (United States)

^g NORTHEAST NORMAL UNIVERSITY   (China)

^h WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Antioxidant; Gene expression; Inflammation; Recombinant human lactoferrin

Indexed keywords

BIOLOGICAL PROPERTIES; CATION EXCHANGE CHROMATOGRAPHY; CHINESE HAMSTER OVARY CELLS; INFLAMMATION; MALDI-TOF MASS SPECTROMETRIC ANALYSIS; POST-TRANSLATIONAL MODIFICATIONS; RECOMBINANT HUMAN LACTOFERRIN; RECOMBINANT HUMAN LACTOFERRIN (RHLF);

ANTIOXIDANTS; CELL CULTURE; GENE EXPRESSION; MAMMALS; POLYSACCHARIDES; PROTEINS; PURIFICATION;

BODY FLUIDS;

COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; GLYCAN; LACTOFERRIN; PEROXIREDOXIN; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BREAST MILK; CHO CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION SYSTEM; HUMAN; ION EXCHANGE CHROMATOGRAPHY; ISOELECTRIC POINT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PURIFICATION; STREPTOCOCCUS PNEUMONIAE; UPREGULATION;

CRICETULUS GRISEUS; EUKARYOTA; MAMMALIA;

ANTIOXIDANT; BACILLUS CALMETTE-GUÉRIN VACCINE; BCG; CFU; CHINESE HAMSTER OVARY CELLS; CHO; COLONY FORMING UNITS; COX; CYCLOOXYGENASE; ELISA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLUTATHIONE PEROXIDASE; GPX; HEK; HLF; HUMAN EPITHELIAL KINDNEY CELLS; HUMAN MILK LACTOFERRIN; ICP-MS; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; INFLAMMATION; LIPOPOLYSACCHARIDE; LPS; MALDI-TOF; MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHT; METHOTREXATE; MTX; PEROXIREDOXINS; PRDX; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE; PTGS; REACTIVE OXYGEN SPECIES; RECOMBINANT HUMAN LACTOFERRIN; RHLF; ROS; SOD; SUPEROXIDE DISMUTASE; TF; TRANSFERRIN;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GENE EXPRESSION; GLYCOSYLATION; HUMANS; LACTOFERRIN; MASS SPECTROMETRY; NEUTROPHILS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS;

EID: 84888847586     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2013.09.011     Document Type: Article

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