Heterogeneity in utilization of N-glycosylation sites Asn624 and Asn138 in human lactoferrin : A study with glycosylation-site mutants

Biochemical Journal

Volumn 319, Issue 1, 1996, Pages 117-122

  Van Berkel, Patrick H C ^a   Van Veen, Harry A ^b   Geerts, Marlieke E J ^b   De Boer, Herman A ^a   Nuijens, Jan H ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Pharming Group NV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; GLUTAMINE; GLYCOPROTEIN; LACTOFERRIN; MUTANT PROTEIN; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL LINE; CONTROLLED STUDY; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLAMMATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; PROTEIN SECRETION;

ASPARAGINE; DENSITOMETRY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMANS; LACTOFERRIN; MOLECULAR WEIGHT; MUTAGENESIS, SITE-DIRECTED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029810761     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3190117     Document Type: Article

References (41)

1. Andersen, B. F., Baker, H. M., Norris, G. E., Rice, D. W. and Baker, E. N. (1989) J. Mol. Biol. 209, 711-734
2. Sanchez, L., Calvo, M. and Brock, J. H. (1992) Arch. Dis. Childh. 67, 657-661
3. Reiter, B., Brock, J. H. and Steel, E. D. (1975) Immunology 28, 83-95
4. Arnold, R. R., Cole, M. F. and McGhee, J. R. (1977) Science 197, 263-265
5. Kijlstra, A. and Jeurissen, S. H. M. (1982) Immunology 47, 263-270
6. Brigitan, B. E., Hassett, D. J., Rosen, G. M., Hamill, D. R. and Cohen, M. S. (1989) Biochem. J. 264, 447-455
7. Crouch, S. P. M., Slater, K. J. and Fletcher, J. (1992) Blood 80, 235-240
8. Appelmelk, B. J., An, Y. Q., Geerts, M., Thijs, B. G., de Boer, H. A., MacLaren, D. M., de Graaff, J. and Nuijens, J. H. (1994) Infect. Immun. 62, 2628-2632
9. Rey, M. W., Woloshuk, S. L. de Boer, H. A. and Pieper, F. R. (1990) Nucleic Acids Res. 18, 5288
10. Anderson, B. F., Baker, H. M., Norris, G. E., Rumball, S. V. and Baker, E. N. (1990) Nature (London) 344, 784-787
11. Spik, G., Strecker, G., Fournet, B., Bouquelet, S., Montreuil, J., Dorland, L., van Halbeek, H. and Vliegenthart, J. F. G. (1982) Eur. J. Biochem. 121, 413-419
12. Opdenakker, G., Rudd, P. M., Ponting, C. P. and Dwek, R. A. (1993) FASEB J. 7, 1330-1337
13. Mohonen, I. and Karjalainen, M. (1984) Biochim. Biophys. Acta 788, 364-367
14. Nakai, K. and Kanehisa, M. (1988) J. Biochem. (Tokyo) 104, 693-699
15. Allen, S. A., Naim, H. Y. and Bulleid. N. J. (1995) J. Biol. Chem. 270, 4797-4804
16. Grinnell, B. W., Walls, J. D. and Gerlitz, B. (1991) J. Biol. Chem. 226, 9778-9785
17. Spik, G., Coddeville, B. and Montreuil, J. (1988) Biochimie 70, 1459-1469
18. van Berkel, P. H. C., Geerts, M. E. J., van Veen, H. A., Kooiman, P. M., Pieper, F. R., de Boer, H. A. and Nuijens, J. H. (1995) Biochem. J. 312, 107-114
19. Powell, M. J. and Ogden, J. E. (1990) Nucleic Acids Res. 18, 4013
20. Panella, T. J., Liu, Y., Huang, A. T. and Teng, C. T. (1991) Cancer Res. 51, 3037-3043
21. Liang, Q. and Richardson, T. (1993) J. Agric. Food Chem. 41, 1800-1807
22. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 488-492
23. Konings, R. N. H., Luiten, R. G. M. and Peeters, B. P. H. (1986) Gene 46, 269-276
24. Deng, W. P. and Nickoloff, J. A. (1992) Anal. Biochem. 200, 81-88
25. Argos, P. (1987) J. Mol. Biol. 197, 331-348
26. Towbin, H., Staehelin, T. and Gordon, J. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354
27. Nuijens, J. H., Abbink, J. J., Wachtfogel, Y. T., Colman, R. W., Eerenberg, A. J. M., Dors, D., Kamp, A. J. M., Strack van Schijndel, R. J. M., Thijs, L. G. and Hack, C. E. (1992) J. Lab. Clin. Med. 119, 159-168
28. McClure, D. B., Walls, J. D. and Grinnell, B. W. (1992) J. Biol. Chem. 267, 19710-19717
29. Legrand, D., Salmon, V., Coddeville, B., Benaissa, M., Plancke, Y. and Spik, G. (1995) FEBS Lett. 365, 57-60
30. Ward, P. P., Piddington, C. S., Cunningham, G. A., Zhou, X., Wyatt, R. D. and Conneely, O. M. (1995) Bio/Technology 13, 498-503
31. Kasturi, L., Eshleman, J. R., Wunner, W. H. and Shakin-Eshleman, S. H. (1995) J. Biol. Chem. 270, 14756-14761
32. Hasegawa, M., Orita, T., Kojima, T., Tomonoh, K., Hirata, Y. and Ochi, N. (1992) Eur. J. Biochem. 210, 9-12
33. Sawidou, G., Klein, M., Grey, A. A., Dorrington, K. J. and Carver, J. P. (1984) Biochemistry 23, 3736-3740
34. Platenburg, G. J., Kootwijk, E. P. A., Kooiman, P. M., Woloshuk, S. L., Nuijens, J. H., Krimpenfort, P. J. A., Pieper, F. R., de Boer, H. A. and Strijker, R. (1994) Transgenic Res. 3, 99-108
35. Derisbourg, P., Wieruszeski, J. M., Montreuil, J. and Spik, G. (1990) Biochem. J. 269, 821-825
36. Parekh, R. B., Tse, A. G. D., Dwek, R. A., Williams, A. F. and Rademacher, T. W. (1987) EMBO J. 6, 1233-1244
37. Sato, T., Takio, K., Kobata, A., Greenwalt, D. E. and Furukawa, K. (1995) J. Biochem. 117, 147-157
38. Kawakami, H. and Lönnerdal, B. (1991) Am. J. Physiol. 261, G841-G846
39. Alcantara, J., Padda, J. S. and Schryvers, A. B. (1992) Can. J. Microbiol. 38, 1202-1205
40. Imber, M. J. and Pizzo, S. V. (1983) Biochem. J. 212, 249-257
41. Legrand, D., Mazurier, J., Colavizza, D., Montreuil, J. and Spik, G. (1990) Biochem. J. 266, 575-581