-
1
-
-
33747338728
-
Tumor necrosis factor inhibitors for rheumatoid arthritis
-
Scott D.L., Kingsley G.H. Tumor necrosis factor inhibitors for rheumatoid arthritis. N. Engl. J. Med. 2006, 355:704-712.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 704-712
-
-
Scott, D.L.1
Kingsley, G.H.2
-
2
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes I.B., Schett G. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 2011, 365:2205-2219.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
3
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T., Deng C.X., Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009, 460:587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
4
-
-
33751113602
-
Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
-
Haigis M.C., Guarente L.P. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev. 2006, 20:2913-2921.
-
(2006)
Genes Dev.
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
5
-
-
80052453175
-
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
-
Niederer F., Ospelt C., Brentano F., Hottiger M.O., Gay R.E., Gay S., Detmar M., Kyburz D. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann. Rheum. Dis. 2011, 70:1866-1873.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1866-1873
-
-
Niederer, F.1
Ospelt, C.2
Brentano, F.3
Hottiger, M.O.4
Gay, R.E.5
Gay, S.6
Detmar, M.7
Kyburz, D.8
-
6
-
-
77951717549
-
SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway
-
Gagarina V., Gabay O., Dvir-Ginzberg M., Lee E.J., Brady J.K., Quon M.J., Hall D.J. SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. Arthritis Rheum. 2010, 62:1383-1392.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 1383-1392
-
-
Gagarina, V.1
Gabay, O.2
Dvir-Ginzberg, M.3
Lee, E.J.4
Brady, J.K.5
Quon, M.J.6
Hall, D.J.7
-
7
-
-
69449107308
-
SIRT1 regulation of apoptosis of human chondrocytes
-
Takayama K., Ishida K., Matsushita T., Fujita N., Hayashi S., Sasaki K., Tei K., Kubo S., Matsumoto T., Fujioka H., Kurosaka M., Kuroda R. SIRT1 regulation of apoptosis of human chondrocytes. Arthritis Rheum. 2009, 60:2731-2740.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2731-2740
-
-
Takayama, K.1
Ishida, K.2
Matsushita, T.3
Fujita, N.4
Hayashi, S.5
Sasaki, K.6
Tei, K.7
Kubo, S.8
Matsumoto, T.9
Fujioka, H.10
Kurosaka, M.11
Kuroda, R.12
-
8
-
-
85027953113
-
Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice
-
Gabay O., Oppenhiemer H., Meir H., Zaal K., Sanchez C., Dvir-Ginzberg M. Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. Ann. Rheum. Dis. 2012, 71:613-616.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 613-616
-
-
Gabay, O.1
Oppenhiemer, H.2
Meir, H.3
Zaal, K.4
Sanchez, C.5
Dvir-Ginzberg, M.6
-
9
-
-
78650978303
-
Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions
-
Fujita N., Matsushita T., Ishida K., Kubo S., Matsumoto T., Takayama K., Kurosaka M., Kuroda R. Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions. J. Orthop. Res. 2011, 29:511-515.
-
(2011)
J. Orthop. Res.
, vol.29
, pp. 511-515
-
-
Fujita, N.1
Matsushita, T.2
Ishida, K.3
Kubo, S.4
Matsumoto, T.5
Takayama, K.6
Kurosaka, M.7
Kuroda, R.8
-
10
-
-
84879858356
-
Overexpression of SIRT6 suppresses inflammatory responses and bone destruction in collagen-induced arthritic mice
-
Lee H.S., Ka S.O., Lee S.M., Lee S.I., Park J.W., Park B.H. Overexpression of SIRT6 suppresses inflammatory responses and bone destruction in collagen-induced arthritic mice. Arthritis Rheum. 2013, 65:1776-1785.
-
(2013)
Arthritis Rheum.
, vol.65
, pp. 1776-1785
-
-
Lee, H.S.1
Ka, S.O.2
Lee, S.M.3
Lee, S.I.4
Park, J.W.5
Park, B.H.6
-
11
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara T.L., Michishita E., Adler A.S., Damian M., Berber E., Lin M., McCord R.A., Ongaigui K.C., Boxer L.D., Chang H.Y., Chua K.F. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell 2009, 136:62-74.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
Chua, K.F.11
-
12
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-β toxicity through inhibiting NF-κB signaling
-
Chen J., Zhou Y., Mueller-Steiner S., Chen L.-F., Kwon H., Yi S., Mucke L., Gan L. SIRT1 protects against microglia-dependent amyloid-β toxicity through inhibiting NF-κB signaling. J. Biol. Chem. 2005, 280:40364-40374.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.-F.4
Kwon, H.5
Yi, S.6
Mucke, L.7
Gan, L.8
-
13
-
-
78649738291
-
SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310
-
Rothgiesser K.M., Erener S., Waibel S., Lüscher B., Hottiger M.O. SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310. J. Cell Sci. 2010, 123:4251-4258.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 4251-4258
-
-
Rothgiesser, K.M.1
Erener, S.2
Waibel, S.3
Lüscher, B.4
Hottiger, M.O.5
-
15
-
-
77954937171
-
The changing face of rheumatoid arthritis: sustained remission for all?
-
Isaacs J.D. The changing face of rheumatoid arthritis: sustained remission for all?. Nat. Rev. Immunol. 2010, 10:605-611.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 605-611
-
-
Isaacs, J.D.1
-
16
-
-
42949171833
-
NF-κB and its relevance to arthritis and inflammation
-
Simmonds R.E., Foxwell B.M. NF-κB and its relevance to arthritis and inflammation. Rheumatology 2008, 47:584-590.
-
(2008)
Rheumatology
, vol.47
, pp. 584-590
-
-
Simmonds, R.E.1
Foxwell, B.M.2
-
17
-
-
84888839715
-
PTU-154 Sirt2 modulates the inflammatory response in oesophageal adenocarcinoma
-
Schulz L.K.E., Lao-Sirieix P., Donovan M.O., Fitzgerald R.C. PTU-154 Sirt2 modulates the inflammatory response in oesophageal adenocarcinoma. Gut 2013, 62:A111.
-
(2013)
Gut
, vol.62
-
-
Schulz, L.K.E.1
Lao-Sirieix, P.2
Donovan, M.O.3
Fitzgerald, R.C.4
-
18
-
-
84885173084
-
The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation
-
Pais T.F., Szego E.M., Marques O., Miller-Fleming L., Antas P., Guerreiro P., de Oliveira R.M., Kasapoglu B., Outeiro T.F. The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation. EMBO J. 2013, 32:2603-2616.
-
(2013)
EMBO J.
, vol.32
, pp. 2603-2616
-
-
Pais, T.F.1
Szego, E.M.2
Marques, O.3
Miller-Fleming, L.4
Antas, P.5
Guerreiro, P.6
de Oliveira, R.M.7
Kasapoglu, B.8
Outeiro, T.F.9
-
19
-
-
84865375172
-
Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction
-
Boissier M.-C., Semerano L., Challal S., Saidenberg-Kermanac'h N., Falgarone G. Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. J. Autoimmun. 2012, 39:222-228.
-
(2012)
J. Autoimmun.
, vol.39
, pp. 222-228
-
-
Boissier, M.-C.1
Semerano, L.2
Challal, S.3
Saidenberg-Kermanac'h, N.4
Falgarone, G.5
-
20
-
-
80055113353
-
Activation of Sirt1 by resveratrol inhibits TNF-alpha induced inflammation in fibroblasts
-
Zhu X., Liu Q., Wang M., Liang M., Yang X., Xu X., Zou H., Qiu J. Activation of Sirt1 by resveratrol inhibits TNF-alpha induced inflammation in fibroblasts. PLoS One 2011, 6:e27081.
-
(2011)
PLoS One
, vol.6
-
-
Zhu, X.1
Liu, Q.2
Wang, M.3
Liang, M.4
Yang, X.5
Xu, X.6
Zou, H.7
Qiu, J.8
-
21
-
-
82955235595
-
Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function
-
Xuzhu G., Komai-Koma M., Leung B.P., Howe H.S., McSharry C., McInnes I.B., Xu D. Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Ann. Rheum. Dis. 2012, 71:129-135.
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 129-135
-
-
Xuzhu, G.1
Komai-Koma, M.2
Leung, B.P.3
Howe, H.S.4
McSharry, C.5
McInnes, I.B.6
Xu, D.7
-
22
-
-
77956677458
-
Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress
-
Schug T.T., Xu Q., Gao H., Peres-da-Silva A., Draper D.W., Fessler M.B., Purushotham A., Li X. Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Mol. Cell. Biol. 2010, 30:4712-4721.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4712-4721
-
-
Schug, T.T.1
Xu, Q.2
Gao, H.3
Peres-da-Silva, A.4
Draper, D.W.5
Fessler, M.B.6
Purushotham, A.7
Li, X.8
-
23
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., Mayo M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 2004, 23:2369-2380.
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
24
-
-
84868473102
-
Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment
-
Schett G., Gravallese E. Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment. Nat. Rev. Rheumatol. 2012, 8:656-664.
-
(2012)
Nat. Rev. Rheumatol.
, vol.8
, pp. 656-664
-
-
Schett, G.1
Gravallese, E.2
-
25
-
-
70349968220
-
Il-17 as a future therapeutic target for rheumatoid arthritis
-
Berg W.B.v.d., Miossec P. Il-17 as a future therapeutic target for rheumatoid arthritis. Nat. Rev. Immunol. 2009, 5:549-553.
-
(2009)
Nat. Rev. Immunol.
, vol.5
, pp. 549-553
-
-
Berg, W.1
Miossec, P.2
-
26
-
-
84881034102
-
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection
-
Eskandarian H.A., Impens F., Nahori M.A., Soubigou G., Coppee J.Y., Cossart P., Hamon M.A. A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection. Science 2013, 341:1238858.
-
(2013)
Science
, vol.341
, pp. 1238858
-
-
Eskandarian, H.A.1
Impens, F.2
Nahori, M.A.3
Soubigou, G.4
Coppee, J.Y.5
Cossart, P.6
Hamon, M.A.7
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