Nanodroplet-mediated histotripsy for image-guided targeted ultrasound cell ablation

Theranostics

Volumn 3, Issue 11, 2013, Pages 851-864

  Vlaisavljevich, Eli ^a   Durmaz, Yasemin Yuksel ^a   Maxwell, Adam ^b   ElSayed, Mohamed ^a   Xu, Zhen ^a,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cavitation; Histotripsy; Nanodroplets; Targeted cell ablation; Therapeutic ultrasound

Indexed keywords

ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; CROSS LINKING; ERYTHROCYTE; HISTOTRIPSY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMAGE QUALITY; MATERIAL STATE; MICROBUBBLE; NANODEVICE; NANODROPLET; NANOENCAPSULATION; PARTICLE SIZE; SIMULATION; TARGET CELL DESTRUCTION; TUMOR CELL; TUMOR VASCULARIZATION; ULTRASOUND THERAPY;

CAVITATION; HISTOTRIPSY; NANODROPLETS; TARGETED CELL ABLATION.; THERAPEUTIC ULTRASOUND;

ABLATION TECHNIQUES; ANIMALS; DOGS; ERYTHROCYTES; FLUOROCARBONS; MICROSCOPY, VIDEO; MODELS, THEORETICAL; MOLECULAR TARGETED THERAPY; NANOPARTICLES; NEOPLASMS; ULTRASONIC THERAPY;

EID: 84888808200     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.6717     Document Type: Article

References (53)

1. Campbell RB. Tumor physiology and delivery of nanopharmaceuticals. Anticancer Agents Med Chem. 2006; 6: 503-12.
2. Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci U S A. 1998; 95: 4607-12.
3. Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev. 2011; 63: 131-5.
4. Fang J, Nakamura H, Maeda H. The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev. 2011; 63: 136-51.
5. Gao Z, Kennedy AM, Christensen DA, Rapoport NY. Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy. Ultrasonics. 2008; 48: 260-70. Epub 2007 Nov 19.
6. Kawabata Ki, Asami R, Yoshikawa H, Azuma T, Umemura Si. Sustaining Microbubbles Derived from Phase Change Nanodroplet by Low-Amplitude Ultrasound Exposure. Jpn J Appl Phys. 2010; 49: 07HF20.
7. Sheeran PS, Luois S, Dayton PA, Matsunaga TO. Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound. Langmuir. 2011; 27: 10412-20.
8. Sheeran PS, Wong VP, Luois S, McFarland RJ, Ross WD, Feingold S, et al. Decafluorobutane as a Phase-Change Contrast Agent for Low-Energy Extravascular Ultrasonic Imaging. Ultrasound Med Biol. 2011; 37: 1518-30.
9. Du L, Jin Y, Zhou W, Zhao J. Ultrasound-Triggered Drug Release and Enhanced Anticancer Effect of Doxorubicin-Loaded Poly(D,L-Lactide-co-Glycolide)-Methoxy-Poly(Ethylene Glycol) Nanodroplets. Ultrasound Med Biol. 2011; 37: 1252-58.
10. Rapoport N, Nam KH, Gupta R, Gao Z, Mohan P, Payne A, et al. Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions. J Control Release. 2011; 153: 4-15.
11. Rapoport NY, Nam KH, Gao Z, Kennedy A. Application of Ultrasound for Targeted Nanotherapy of Malignant Tumors. Acoust Phys. 2009; 55: 594-601.
12. Gao Z, Kennedy AM, Christensen DA, Rapoport NY. Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy. Ultrasonics. 2008; 48: 260-70.
13. Kripfgans OD, Fowlkes JB, Miller DL, Eldevik OP, Carson PL. Acoustic droplet vaporization for therapeutic and diagnostic applications. Ultrasound Med Biol. 2000; 26: 1177-89.
14. Sheeran PS, Wong VP, Luois S, McFarland RJ, Ross WD, Feingold S, et al. Decafluorobutane as a Phase-Change Contrast Agent for Low-Energy Extravascular Ultrasonic Imaging. Ultrasound Med Biol. 2011; 37: 1518-30.
15. Kawabata K, Asami R, Axuma T, Umemura S. Acoustic response of microbubbles derived from phase-change nanodroplet. Jpn J Appl Phys. 2010; 49: 07HF18.
16. Sheeran PS, Luois S, Dayton PA, Matsunaga TO. Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound. Langmuir. 2011; 27: 10412-20.
17. Wilson K, Homan K, Emelianov S. Biomedical photoacoustics beyond thermal expansion using triggered nanodroplet vaporization for contrast-enhanced imaging. Nat Commun. 2012; 3: 618.
18. Kawabata Ki, Asami R, Azuma T, Yoshikawa H, Umemura Si. Cavitation assisted HIFU with phase-change nano droplet. IEEE International Ultrasonics Symposium. 2008;: 780-3.
19. Kopechek JA, Zhang P, Burgess MT, Porter TM. Synthesis of phase-shift nanoemulsions with narrow size distributions for acoustic droplet vaporization and bubble-enhanced ultrasound-mediated ablation. J Vis Exp. 2012;: e4308.
20. Zhang M, Fabiilli ML, Haworth KJ, Padilla F, Swanson SD, Kripfgans OD, et al. Acoustic droplet vaporization for enhancement of thermal ablation by high intensity focused ultrasound. Acad Radiol. 2011; 18: 1123-32.
21. Kieran K, Hall TL, Parsons JE, Wolf JS, Jr., Fowlkes JB, Cain CA, et al. Refining histotripsy: defining the parameter space for the creation of nonthermal lesions with high intensity, pulsed focused ultrasound of the in vitro kidney. J Urol. 2007; 178: 672-6.
22. Winterroth F, Xu Z, Wang TY, Wilkinson JE, Fowlkes JB, Roberts WW, et al. Examining and analyzing subcellular morphology of renal tissue treated by histotripsy. Ultrasound Med Biol. 2011; 37: 78-86.
23. Xu Z, Fan Z, Hall TL, Winterroth F, Fowlkes JB, Cain CA. Size measurement of tissue debris particles generated from pulsed ultrasound cavitational therapy-histotripsy. Ultrasound Med Biol. 2009; 35: 245-55.
24. Xu Z, Fowlkes JB, Cain CA. A new strategy to enhance cavitational tissue erosion using a high-intensity, Initiating sequence. IEEE Trans Ultrason Ferroelectr Freq Control. 2006; 53: 1412-24.
25. Xu Z, Fowlkes JB, Rothman ED, Levin AM, Cain CA. Controlled ultrasound tissue erosion: the role of dynamic interaction between insonation and microbubble activity. J Acoust Soc Am. 2005; 117: 424-35.
26. Xu Z, Ludomirsky A, Eun LY, Hall TL, Tran BC, Fowlkes JB, et al. Controlled ultrasound tissue erosion. IEEE Trans Ultrason Ferroelectr Freq Control. 2004; 51: 726-36.
27. Maxwell AD, Owens G, Gurm HS, Ives K, Myers DD, Jr., Xu Z. Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model. J Vasc Interv Radiol. 2011; 22: 369-77.
28. Xu Z, Owens G, Gordon D, Cain C, Ludomirsky A. Noninvasive creation of an atrial septal defect by histotripsy in a canine model. Circulation. 2010; 121: 742-9.
29. Durmaz H, Dag A, Altintas O, Erdogan T, Hizal G, Tunca U. One-pot synthesis of ABC type triblock copolymers via in situ click 3+2 and Diels-Alder 4+2 reactions. Macromolecules 2007; 40: 191-98.
30. Durmaz YY, Vlaisavljevich E, Xu Z, Elsayed MEH. Development of targeted nano-bubbles for ultrasound imaging and ablation of prostate cancer. 35th Annual Symposium of Macromolecular Science & Engineering. Ann Arbor, Michigan. 2011.
31. Durmaz YY, Vlaisavljevich E, Xu Z, ElSayed MEH. Development of nanodroplets for targeted ultrasound-mediated ablation of cancer. Engineering Graduate Symposium. Ann Arbor, Michigan. 2011.
32. Bartczak D, Kanaras AG. Preparation of peptide-functionalized gold nanoparticles using one pot EDC/sulfo-NHS coupling. Langmuir. 2011; 27: 10119-23.
33. Nam K, Kimura T, Kishida A. Controlling coupling reaction of EDC and NHS for preparation of collagen gels using ethanol/water co-solvents. Macromol Biosci. 2008; 8: 32-7.
34. Wildling L, Unterauer B, Zhu R, Rupprecht A, Haselgrubler T, Rankl C, et al. Linking of sensor molecules with amino groups to amino-functionalized AFM tips. Bioconjug Chem. 2011; 22: 1239-48.
35. Yang X, Church CC. A model for the dynamics of gas bubbles in soft tissue. J Acoust Soc Am. 2005; 118: 3595-606.
36. Maxwell AD, Cain CA, Hall TL, Fowlkes JB, Xu Z. Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials. Ultrasound Med Biol. 2013; 39: 449-65.
37. Sheeran PS, Dayton PA. Phase-change contrast agents for imaging and therapy. Curr Pharm Des. 2012; 18: 2152-65.
38. Masuzaki R, Tateishi R, Yoshida H, Sato T, Ohki T, Goto T, et al. Assessing liver tumor stiffness by transient elastography. Hepatol Int. 2007; 1: 394-7.
39. Zhang M, Nigwekar P, Castaneda B, Hoyt K, Joseph JV, di Sant'Agnese A, et al. Quantitative characterization of viscoelastic properties of human prostate correlated with histology. Ultrasound Med Biol. 2008; 34: 1033-42.
40. Friedman M, Strauss M, Amendt P, London R, Glinsky M. Two-dimensional Rayleigh model for bubble evolution in soft tissue. Phys Fluids. 2002; 14: 1768-80.
41. Ayme EJ, Carstensen EL. Cavitation induced by asymmetric distorted pulses of ultrasound: theoretical predictions. IEEE Trans Ultrason Ferroelectr Freq Control. 1989; 36: 32-40.
42. Parsons JE, Cain CA, Fowlkes JB. Cost-effective assembly of a basic fiber-optic hydrophone for measurement of high-amplitude therapeutic ultrasound fields. J Acoust Soc Am. 2006; 119: 1432-40.
43. Normand V, Lootens DL, Amici E, Plucknett KP, Aymard P. New insight into agarose gel mechanical properties. Biomacromolecules. 2000; 1: 730-8.
44. Maxwell AD, Wang TY, Yuan L, Duryea AP, Xu Z, Cain CA. A tissue phantom for visualization and measurement of ultrasound-induced cavitation damage. Ultrasound Med Biol. 2010; 36: 2132-43.
45. O'Reilly RK. Spherical polymer micelles: nanosized reaction vessels? Phil. Trans. R. Soc. A. 2007; 365: 2863-78.
46. Zhulina EB, Adam M, LaRue I, Sheiko SS, Rubinstein M. Diblock Copolymer Micelles in a Dilute Solution. Macromolecules. 2005; 38: 5330-51.
47. Matyjaszewski K, Xia J. Atom Transfer Radical Polymerization. Chem Rev. 2001; 101: 2921-90.
48. Gao Z, Kennedy AM, Christensen DA, Rapoport NY. Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy. Ultrasonics. 2008; 48: 260-70.
49. Shiraishi K, Endoh R, Furuhata H, Nishihara M, Suzuki R, Maruyama K, et al. A facile preparation method of a PFC-containing nano-sized emulsion for theranostics of solid tumors. Int J Pharm. 2011; 421: 379-87.
50. Wang C-H, Kang S-T, Lee Y-H, Luo Y-L, Huang Y-F, Yeh C-K. Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis. Biomaterials. 2012; 33: 1939-47.
51. Apfel RE, Holland CK. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound. Ultrasound Med Biol. 1991; 17: 179-85.
52. Carstensen EL, Gracewski S, Dalecki D. The search for cavitation in vivo. Ultrasound Med Biol. 2000; 26: 1377-85.
53. Leighton TG. The Acoustic Bubble. Academic Press. 1994.