Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

Journal of Controlled Release

Volumn 153, Issue 1, 2011, Pages 4-15

  Rapoport, Natalya ^a   Nam, Kweon Ho ^a   Gupta, Roohi ^a   Gao, Zhongao ^a,c   Mohan, Praveena ^a   Payne, Allison ^b   Todd, Nick ^b   Liu, Xin ^b   Kim, Taeho ^b   Shea, Jill ^b   Scaife, Courtney ^b   Parker, Dennis L ^b   Jeong, Eun Kee ^b   Kennedy, Anne M ^b  

^a Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Fluorine MRI; Fluorine MRS; Pancreatic cancer; Perfluorocarbon nanoemulsion; Ultrasonography; Ultrasound mediated chemotherapy

Indexed keywords

ANIMAL MODEL; BIODISTRIBUTIONS; LONG CIRCULATING; MICROBUBBLES; MR SPECTROSCOPY; MULTIMODAL IMAGING; NANO-DROPLETS; NANO-EMULSIONS; NANOCARRIERS; NANODROPLET; PACLITAXEL; PANCREATIC CANCERS; PERFLUOROCARBONS; SECOND GENERATION; SOLID TUMORS; STABLE CAVITATION; THERAPEUTIC AGENTS; THERAPEUTIC PROPERTIES; THERAPEUTIC ULTRASOUND; TUMOR IMAGING; TUMOR REGRESSION; TUMOR TISSUES; ULTRASOUND IMAGING; ULTRASOUND-MEDIATED CHEMOTHERAPY; NANOEMULSION;

BLOCK COPOLYMERS; CHEMOTHERAPY; COPOLYMERIZATION; CROWN ETHERS; DISEASES; DROPS; EMULSIFICATION; ETHERS; FLUORINE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGICAL MODELS; TUMORS; ULTRASONOGRAPHY; BIOACOUSTICS;

ULTRASONICS;

COPOLYMER; CROWN ETHER DERIVATIVE; FLUOROCARBON; MACROGOL; PACLITAXEL; PERFLUORO 15 CROWN 5 ETHER; PHOSPHOLIPID; POLYCAPROLACTONE; POLYLACTIDE; UNCLASSIFIED DRUG; CROWN ETHER; POLY(ETHYLENE OXIDE) CO POLY(LACTIDE); POLY(ETHYLENE OXIDE) CO POLY(LEVO LACTIDE); POLY(ETHYLENE OXIDE) CO POLYCAPROLACTONE;

ACOUSTICS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BREAST CANCER; CANCER THERAPY; CANCER TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG FORMULATION; ECHOGRAPHY; FLUORINE NUCLEAR MAGNETIC RESONANCE; HUMAN; HUMAN CELL; MICROBUBBLE; MOLECULAR IMAGING; MOLECULAR STABILITY; MOUSE; NANOEMULSION; NONHUMAN; PANCREAS CANCER; PARTICLE SIZE; PRIORITY JOURNAL; THERMOMETRY; ULTRASOUND; ULTRASOUND MEDIATED TUMOR IMAGING; ULTRASOUND MEDIATED TUMOR THERAPY; ULTRASOUND THERAPY; VAPORIZATION; ACOUSTIC DROPLET VAPORIZATION; CANCER MODEL; CANCER REGRESSION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; HIGH INTENSITY FOCUSED ULTRASOUND; METASTASIS INHIBITION; MICELLE; MONITORING; NANOTECHNOLOGY; NANOTHERAPY; NUCLEAR MAGNETIC RESONANCE SCANNER; PHANTOM; ULTRASOUND SCANNER; ULTRASOUND TRANSDUCER;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; EMULSIONS; FEMALE; FLUOROCARBONS; HUMANS; MICE; NANOMEDICINE; NEOPLASMS; PACLITAXEL; PANCREATIC NEOPLASMS; ULTRASONIC THERAPY;

EID: 79960102276     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.01.022     Document Type: Conference Paper

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