메뉴 건너뛰기




Volumn 94, Issue 6, 2013, Pages 1141-1157

At the bedside: Innate immunity as an immunotherapy tool for hematological malignancies

Author keywords

T cells; Graft versus host disease; Graft versus leukemia effect; Haploidentical hematopoietic stem cell transplantation; NK cells

Indexed keywords

BCG VACCINE; BISPHOSPHONIC ACID DERIVATIVE; BROMOHYDRIN PYROPHOSPHATE; CLOFARABINE; COMPACTIN; CYCLOPHOSPHAMIDE; DENILEUKIN DIFTITOX; EPRATUZUMAB; ETOPOSIDE; FLUDARABINE; GAMMA INTERFERON; HYDROCORTISONE; IMMUNOSTIMULATING AGENT; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; KRESTIN; METHYLPREDNISOLONE; MEVALONIC ACID; MONOCLONAL ANTIBODY; OKT 3; PAMIDRONIC ACID; PHOSPHOSTIM; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 2; RITUXIMAB; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZOLEDRONIC ACID;

EID: 84888769265     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0613343     Document Type: Review
Times cited : (45)

References (145)
  • 1
    • 33646119401 scopus 로고    scopus 로고
    • Hematopoietic stem-cell transplantation
    • Copelan, E. A. (2006) Hematopoietic stem-cell transplantation. N. Eng. J. Med. 354, 1813-1826.
    • (2006) N. Eng. J. Med , vol.354 , pp. 1813-1826
    • Copelan, E.A.1
  • 2
    • 0035902174 scopus 로고    scopus 로고
    • Haematopoietic cell transplantation as immunotherapy
    • Appelbaum, F. R. (2001) Haematopoietic cell transplantation as immunotherapy. Nature 411, 385-389.
    • (2001) Nature , vol.411 , pp. 385-389
    • Appelbaum, F.R.1
  • 4
    • 50049084370 scopus 로고    scopus 로고
    • Understanding and harnessing the graft-versus-leukaemia effect
    • Barrett, A. J. (2008) Understanding and harnessing the graft-versus-leukaemia effect. Br. J. Haematol. 142, 877-888.
    • (2008) Br. J. Haematol , vol.142 , pp. 877-888
    • Barrett, A.J.1
  • 5
    • 0842324616 scopus 로고    scopus 로고
    • Minor histocompatibility antigens-big in tumour therapy
    • Spierings, E., Wieles, B., Goulmy, E. (2004) Minor histocompatibility antigens-big in tumour therapy. Trends Immunol. 25, 56-60.
    • (2004) Trends Immunol , vol.25 , pp. 56-60
    • Spierings, E.1    Wieles, B.2    Goulmy, E.3
  • 6
    • 14844286852 scopus 로고    scopus 로고
    • Immunotherapy of cancer through targeting of minor histocompatibility antigens
    • Hambach, L., Goulmy, E. (2005) Immunotherapy of cancer through targeting of minor histocompatibility antigens. Curr. Opin. Immunol. 17, 202-210.
    • (2005) Curr. Opin. Immunol , vol.17 , pp. 202-210
    • Hambach, L.1    Goulmy, E.2
  • 7
    • 77953610444 scopus 로고    scopus 로고
    • Adoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation
    • O'Reilly, R. J., Dao, T., Koehne, G, Scheinberg, D., Doubrovina, E. (2010) Adoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation. Sem. Immunol. 22, 162-172.
    • (2010) Sem. Immunol , vol.22 , pp. 162-172
    • O'Reilly, R.J.1    Dao, T.2    Koehne, G.3    Scheinberg, D.4    Doubrovina, E.5
  • 9
    • 0037103358 scopus 로고    scopus 로고
    • Chronic graft-versus-host disease in children: Incidence, risk factors, and impact on outcome
    • AIEOP-BMT Group, Italian Association for Pediatric Hematology and Oncology-Bone Marrow Transplant
    • Zecca, M., Prete, A., Rondelli, R., Lanino, E., Balduzzi, A., Messina, C, Fagioli, F., Porta, F., Favre, C, Pession, A., Locatelli, F., AIEOP-BMT Group, Italian Association for Pediatric Hematology and Oncology-Bone Marrow Transplant (2002) Chronic graft-versus-host disease in children: incidence, risk factors, and impact on outcome. Blood 100, 1192-1200.
    • (2002) Blood , vol.100 , pp. 1192-1200
    • Zecca, M.1    Prete, A.2    Rondelli, R.3    Lanino, E.4    Balduzzi, A.5    Messina, C.6    Fagioli, F.7    Porta, F.8    Favre, C.9    Pession, A.10    Locatelli, F.11
  • 10
    • 38849112548 scopus 로고    scopus 로고
    • Searching for alternative hematopoietic stem cell donors for pediatric patients
    • Rocha, V., Locatelli, F. (2008) Searching for alternative hematopoietic stem cell donors for pediatric patients. Bone Marrow Transplant. 41, 207-214.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 207-214
    • Rocha, V.1    Locatelli, F.2
  • 11
    • 82955217779 scopus 로고    scopus 로고
    • Haploidentical hematopoietic transplantation: Current status and future perspectives
    • Reisner, Y., Hagin, D., Martelli, M. F. (2011) Haploidentical hematopoietic transplantation: current status and future perspectives. Blood 118, 6006-6017.
    • (2011) Blood , vol.118 , pp. 6006-6017
    • Reisner, Y.1    Hagin, D.2    Martelli, M.F.3
  • 13
    • 0028789191 scopus 로고
    • Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice
    • Bachar-Lustig, E., Rachamim, N., Li, H. W., Lan, F., Reisner, Y. (1995) Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice. Nat. Med. 1, 1268-1273.
    • (1995) Nat. Med , vol.1 , pp. 1268-1273
    • Bachar-Lustig, E.1    Rachamim, N.2    Li, H.W.3    Lan, F.4    Reisner, Y.5
  • 14
    • 0028125191 scopus 로고
    • Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum
    • Aversa, F., Tabilio, A., Terenzi, A., Velardi, A., Falzetti, F., Giannoni, C, Iacucci, R., Zei, T., Martelli, M. P., Gambelunghe, C, et al. (1994) Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum. Blood 84, 3948-3955.
    • (1994) Blood , vol.84 , pp. 3948-3955
    • Aversa, F.1    Tabilio, A.2    Terenzi, A.3    Velardi, A.4    Falzetti, F.5    Giannoni, C.6    Iacucci, R.7    Zei, T.8    Martelli, M.P.9    Gambelunghe, C.10
  • 17
    • 77951745554 scopus 로고    scopus 로고
    • Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplantation in children with very high-risk acute lymphoblastic leukemia: Impact of center size: An analysis on behalf of the Acute Leukemia and Pediatric Disease Working Parties of the European Blood and Marrow Transplant group
    • Pediatric Diseases and Acute Leukemia Working Parties of the European Group for Blood and Marrow Transplantation (EBMT)
    • Klingebiel, T., Cornish, J., Labopin, M., Locatelli, F., Darbyshire, P., Handgretinger, R., Balduzzi, A., Owoc-Lempach, J., Fagioli, F., Or, R., Peters, C, Aversa, F., Polge, E., Dini, G, Rocha, V., Pediatric Diseases and Acute Leukemia Working Parties of the European Group for Blood and Marrow Transplantation (EBMT). (2010) Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplantation in children with very high-risk acute lymphoblastic leukemia: impact of center size: an analysis on behalf of the Acute Leukemia and Pediatric Disease Working Parties of the European Blood and Marrow Transplant group. Blood 115, 3437-3446.
    • (2010) Blood , vol.115 , pp. 3437-3446
    • Klingebiel, T.1    Cornish, J.2    Labopin, M.3    Locatelli, F.4    Darbyshire, P.5    Handgretinger, R.6    Balduzzi, A.7    Owoc-Lempach, J.8    Fagioli, F.9    Or, R.10    Peters, C.11    Aversa, F.12    Polge, E.13    Dini, G.14    Rocha, V.15
  • 18
    • 55749091291 scopus 로고    scopus 로고
    • A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: A risk factor analysis of outcomes for patients in remission at transplantation
    • Acute Leukemia Working Party (ALWP) of European Blood and Marrow Transplant (EBMT) Group
    • Ciceri, F., Labopin, M., Aversa, F., Rowe, J. M., Bunjes, D., Lewalle, P., Nagler, A, Di Bartolomeo, P., Lacerda, J. F., Lupo Stanghellini, M. T., Polge, E., Frassoni, F., Martelli, M. F., Rocha, V., Acute Leukemia Working Party (ALWP) of European Blood and Marrow Transplant (EBMT) Group. (2008) A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation. Blood 112, 3574-3581.
    • (2008) Blood , vol.112 , pp. 3574-3581
    • Ciceri, F.1    Labopin, M.2    Aversa, F.3    Rowe, J.M.4    Bunjes, D.5    Lewalle, P.6    Nagler, A.7    Di Bartolomeo, P.8    Lacerda, J.F.9    Lupo, S.M.T.10    Polge, E.11    Frassoni, F.12    Martelli, M.F.13    Rocha, V.14
  • 23
    • 84888812471 scopus 로고    scopus 로고
    • At the bench: Preclinical rationale for exploiting NK cells and 7Ô T lymphocytes for the treatment of high-risk leukemias
    • Norell, H., Moretta, A, Silva-Santos, B., Moretta, L. (2013) At the bench: preclinical rationale for exploiting NK cells and 7Ô T lymphocytes for the treatment of high-risk leukemias. J. Leukoc. Biol. 94, 1123-1139.
    • (2013) J. Leukoc. Biol , vol.94 , pp. 1123-1139
    • Norell, H.1    Moretta, A.2    Silva-Santos, B.3    Moretta, L.4
  • 25
    • 0029003984 scopus 로고
    • Cloning of immunoglobulin-super-family members associated with HLA-C and HLA-B recognition by human natural killer cells
    • Colonna, M., Samaridis, J. (1995) Cloning of immunoglobulin-super-family members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268, 405-408.
    • (1995) Science , vol.268 , pp. 405-408
    • Colonna, M.1    Samaridis, J.2
  • 26
    • 0025677333 scopus 로고
    • Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: Correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition
    • Moretta, A., Bottino, C, Pende, D., Tripodi, G., Tambussi, G., Viale, O., Orengo, A, Barbaresi, M., Merli, A, Ciccone, E., et al. (1990) Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J. Exp. Med. 172, 1589-1598.
    • (1990) J. Exp. Med , vol.172 , pp. 1589-1598
    • Moretta, A.1    Bottino, C.2    Pende, D.3    Tripodi, G.4    Tambussi, G.5    Viale, O.6    Orengo, A.7    Barbaresi, M.8    Merli, A.9    Ciccone, E.10
  • 27
    • 0025267879 scopus 로고
    • A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function
    • Moretta, A., Tambussi, G., Bottino, C, Tripodi, G., Merli, A, Ciccone, E., Pantaleo, G., Moretta, L. (1990) A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J. Exp. Med. 171, 695-714.
    • (1990) J. Exp. Med , vol.171 , pp. 695-714
    • Moretta, A.1    Tambussi, G.2    Bottino, C.3    Tripodi, G.4    Merli, A.5    Ciccone, E.6    Pantaleo, G.7    Moretta, L.8
  • 28
    • 0027284452 scopus 로고
    • P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities
    • Moretta, A., Vitale, M., Bottino, C, Orengo, A. M., Morelli, L., Augugli-aro, R, Barbaresi, M., Ciccone, E., Moretta, L. (1993) P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J. Exp. Med. 178, 597-604.
    • (1993) J. Exp. Med , vol.178 , pp. 597-604
    • Moretta, A.1    Vitale, M.2    Bottino, C.3    Orengo, A.M.4    Morelli, L.5    Augugli-Aro, R.6    Barbaresi, M.7    Ciccone, E.8    Moretta, L.9
  • 29
    • 78751689960 scopus 로고    scopus 로고
    • Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation
    • Moretta, L., Locatelli, F., Pende, D., Marcenaro, E., Mingari, M. C, Moretta, A. (2011) Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation. Blood 117, 764-771.
    • (2011) Blood , vol.117 , pp. 764-771
    • Moretta, L.1    Locatelli, F.2    Pende, D.3    Marcenaro, E.4    Mingari, M.C.5    Moretta, A.6
  • 31
    • 14944355535 scopus 로고    scopus 로고
    • MHC class I molecules and KIRs in human history, health and survival
    • Parham, P. (2005) MHC class I molecules and KIRs in human history, health and survival. Nat. Rev. Immunol. 5, 201-214.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 201-214
    • Parham, P.1
  • 33
    • 84859159747 scopus 로고    scopus 로고
    • NK cell MHC class I specific receptors (KIR): From biology to clinical intervention
    • Thielens, A, Vivier, E., Romagne, F. (2012) NK cell MHC class I specific receptors (KIR): from biology to clinical intervention. Curr. Opin. Immunol. 24, 239-245.
    • (2012) Curr. Opin. Immunol , vol.24 , pp. 239-245
    • Thielens, A.1    Vivier, E.2    Romagne, F.3
  • 34
  • 35
    • 0033963020 scopus 로고    scopus 로고
    • Immune reconstitution after transplantation of autologous peripheral CD34+ cells: Analysis of predictive factors and comparison with unselected progenitor transplants
    • Rutella, S., Rumi, C, Laurenti, L., Pierelli, L., Sora, F., Sica, S., Leone, G. (2000) Immune reconstitution after transplantation of autologous peripheral CD34+ cells: analysis of predictive factors and comparison with unselected progenitor transplants. Br. J. Haematol. 108, 105-115.
    • (2000) Br. J. Haematol , vol.108 , pp. 105-115
    • Rutella, S.1    Rumi, C.2    Laurenti, L.3    Pierelli, L.4    Sora, F.5    Sica, S.6    Leone, G.7
  • 38
    • 84883723997 scopus 로고    scopus 로고
    • Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: Role of alloreactive NK cells
    • Locatelli, F., Pende, D., Mingari, M. C, Bertaina, A, Falco, M., Moretta, A., Moretta, L. (2013) Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells. Front. Immunol. 4, 15.
    • (2013) Front. Immunol , vol.4 , pp. 15
    • Locatelli, F.1    Pende, D.2    Mingari, M.C.3    Bertaina, A.4    Falco, M.5    Moretta, A.6    Moretta, L.7
  • 39
    • 0037111776 scopus 로고    scopus 로고
    • Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor
    • Davies, S. M., Ruggieri, L., DeFor, T., Wagner, J. E., Weisdorf, D. J., Miller, J. S., Velardi, A, Blazar, B. R (2002) Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor. Blood 100, 3825-3827.
    • (2002) Blood , vol.100 , pp. 3825-3827
    • Davies, S.M.1    Ruggieri, L.2    Defor, T.3    Wagner, J.E.4    Weisdorf, D.J.5    Miller, J.S.6    Velardi, A.7    Blazar, B.R.8
  • 41
    • 1642377663 scopus 로고    scopus 로고
    • Role of KIR ligand incompatibility in hematopoietic stem cell transplantation using unrelated donors
    • Bornhauser, M., Schwerdtfeger, R, Martin, H., Frank, K H., Theuser, C, Ehninger, G. (2004) Role of KIR ligand incompatibility in hematopoietic stem cell transplantation using unrelated donors. Blood 103, 2860-2861.
    • (2004) Blood , vol.103 , pp. 2860-2861
    • Bornhauser, M.1    Schwerdtfeger, R.2    Martin, H.3    Frank, K.H.4    Theuser, C.5    Ehninger, G.6
  • 44
    • 67049088404 scopus 로고    scopus 로고
    • Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning inten sity
    • Brunstein, C. G., Wagner, J. E., Weisdorf, D. J., Cooley, S., Noreen, H., Barker, J. N., DeFor, T., Verneris, M. R, Blazar, B. R, Miller, J. S. (2009) Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning inten sity. Blood 113, 5628-5634.
    • (2009) Blood , vol.113 , pp. 5628-5634
    • Brunstein, C.G.1    Wagner, J.E.2    Weisdorf, D.J.3    Cooley, S.4    Noreen, H.5    Barker, J.N.6    Defor, T.7    Verneris, M.R.8    Blazar, B.R.9    Miller, J.S.10
  • 45
    • 0142215546 scopus 로고    scopus 로고
    • T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation
    • Lowe, E. J., Turner, V, Handgretinger, R, Horwitz, E. M., Benaim, E., Hale, G. A, Woodard, P., Leung, W. (2003) T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation. Br. J. Haematol. 123, 323-326.
    • (2003) Br. J. Haematol , vol.123 , pp. 323-326
    • Lowe, E.J.1    Turner, V.2    Handgretinger, R.3    Horwitz, E.M.4    Benaim, E.5    Hale, G.A.6    Woodard, P.7    Leung, W.8
  • 47
    • 20144385362 scopus 로고    scopus 로고
    • Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: Evidence for the involve ment of the poliovirus receptor (CD155) and nectin-2 (CD112)
    • Pende, D., Spaggiari, G. M., Marcenaro, S., Martini, S., Rivera, P., Ca-pobianco, A, Falco, M., Lanino, E., Pierri, I., Zambello, R, Bacigalupo, A, Mingari, M. C, Moretta, A, Moretta, L. (2005) Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involve ment of the poliovirus receptor (CD155) and nectin-2 (CD112). Blood 105, 2066-2073.
    • (2005) Blood , vol.105 , pp. 2066-2073
    • Pende, D.1    Spaggiari, G.M.2    Marcenaro, S.3    Martini, S.4    Rivera, P.5    Ca-Pobianco, A.6    Falco, M.7    Lanino, E.8    Pierri, I.9    Zambello, R.10    Bacigalupo, A.11    Mingari, M.C.12    Moretta, A.13    Moretta, L.14
  • 48
    • 0030039386 scopus 로고    scopus 로고
    • The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions
    • Biassoni, R, Cantoni, C, Falco, M., Verdiani, S., Bottino, C, Vitale, M., Conte, R, Poggi, A, Moretta, A, Moretta, L. (1996) The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J. Exp. Med. 183, 645-650.
    • (1996) J. Exp. Med , vol.183 , pp. 645-650
    • Biassoni, R.1    Cantoni, C.2    Falco, M.3    Verdiani, S.4    Bottino, C.5    Vitale, M.6    Conte, R.7    Poggi, A.8    Moretta, A.9    Moretta, L.10
  • 51
    • 77955512395 scopus 로고    scopus 로고
    • Donor KIR Genes 2DL5A, 2DS1 and 3DS1are associated with a reduced rate of leukemia relapse after HLA-iden-tical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies
    • Stringaris, K, Adams, S., Uribe, M., Eniafe, R, Wu, C. O., Savani, B. N., Barrett, A. J. (2010) Donor KIR Genes 2DL5A, 2DS1 and 3DS1are associated with a reduced rate of leukemia relapse after HLA-iden-tical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies. Biol. Blood Marrow Transplant. 16, 1257-1264.
    • (2010) Biol. Blood Marrow Transplant , vol.16 , pp. 1257-1264
    • Stringaris, K.1    Adams, S.2    Uribe, M.3    Eniafe, R.4    Wu, C.O.5    Savani, B.N.6    Barrett, A.J.7
  • 54
    • 77949532253 scopus 로고    scopus 로고
    • Education of human natural killer cells by activating killer cell immunoglobulin-like receptors
    • Fauriat, C, Ivarsson, M. A, Ljunggren, H. G., Malmberg, K. J., Mi-chaelsson, J. (2010) Education of human natural killer cells by activating killer cell immunoglobulin-like receptors. Blood 115, 1166-1174.
    • (2010) Blood , vol.115 , pp. 1166-1174
    • Fauriat, C.1    Ivarsson, M.A.2    Ljunggren, H.G.3    Malmberg, K.J.4    Mi-Chaelsson, J.5
  • 55
    • 79956049903 scopus 로고    scopus 로고
    • Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: Implications in hap-loidentical HSCT
    • Sivori, S., Carlomagno, S., Falco, M., Romeo, E., Moretta, L., Moretta, A. (2011) Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: implications in hap-loidentical HSCT. Blood 117, 4284-4292.
    • (2011) Blood , vol.117 , pp. 4284-4292
    • Sivori, S.1    Carlomagno, S.2    Falco, M.3    Romeo, E.4    Moretta, L.5    Moretta, A.6
  • 56
    • 67651227579 scopus 로고    scopus 로고
    • Activating and inhibitory killer immunoglobulin-like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high-risk leukaemias
    • Moretta, A., Pende, D., Locatelli, F., Moretta, L. (2009) Activating and inhibitory killer immunoglobulin-like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high-risk leukaemias. Clin. Exp. Immunol. 157, 325-331.
    • (2009) Clin. Exp. Immunol , vol.157 , pp. 325-331
    • Moretta, A.1    Pende, D.2    Locatelli, F.3    Moretta, L.4
  • 58
    • 84879325450 scopus 로고    scopus 로고
    • KIR2DS1-dependent acquisition of CCR7 and migratory properties by human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell blasts
    • Marcenaro, E., Pesce, S., Sivori, S., Carlomagno, S., Moretta, L., Moretta, A. (2013) KIR2DS1-dependent acquisition of CCR7 and migratory properties by human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell blasts. Blood 121, 3396-3401.
    • (2013) Blood , vol.121 , pp. 3396-3401
    • Marcenaro, E.1    Pesce, S.2    Sivori, S.3    Carlomagno, S.4    Moretta, L.5    Moretta, A.6
  • 59
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • Hsu, K. C, Keever-Taylor, C. A, Wilton, A, Pinto, C, Heller, G., Arkun, K, O'Reilly, R J., Horowitz, M. M., Dupont, B. (2005) Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. Blood 105, 4878-4884.
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3    Pinto, C.4    Heller, G.5    Arkun, K.6    O'Reilly, R.J.7    Horowitz, M.M.8    Dupont, B.9
  • 64
    • 77949898005 scopus 로고    scopus 로고
    • NKAML: A pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia
    • Rubnitz, J. E., Inaba, H., Ribeiro, R. C, Pounds, S., Rooney, B., Bell, T., Pui, C. H., Leung, W. (2010) NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. J. Clin. Oncol. 28, 955-959.
    • (2010) J. Clin. Oncol , vol.28 , pp. 955-959
    • Rubnitz, J.E.1    Inaba, H.2    Ribeiro, R.C.3    Pounds, S.4    Rooney, B.5    Bell, T.6    Pui, C.H.7    Leung, W.8
  • 67
    • 77954143558 scopus 로고    scopus 로고
    • 7Ô T cell effector functions: A blend of innate programming and acquired plasticity
    • Bonneville, M., O'Brien, R L., Born, W. K. (2010) 7Ô T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10, 467-478.
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 467-478
    • Bonneville, M.1    O'Brien, R.L.2    Born, W.K.3
  • 70
    • 84865718141 scopus 로고    scopus 로고
    • IL-17-producing y8 T cells and innate lymphoid cells
    • Sutton, C. E., Mielke, L. A, Mills, K. H. (2012) IL-17-producing y8 T cells and innate lymphoid cells. Eur. J. Immunol. 42, 2221-2231.
    • (2012) Eur. J. Immunol , vol.42 , pp. 2221-2231
    • Sutton, C.E.1    Mielke, L.A.2    Mills, K.H.3
  • 72
    • 68649104004 scopus 로고    scopus 로고
    • YS T cells and the lymphoid stress-surveillance response
    • Hayday, A. C. (2009) yS T cells and the lymphoid stress-surveillance response. Immunity 31, 184-196.
    • Immunity , vol.31 , pp. 184-196
    • Hayday, A.1
  • 74
    • 82755192491 scopus 로고    scopus 로고
    • The in-traepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy
    • Strid, J., Sobolev, O., Zafirova, B., Polic, B., Hayday, A. (2011) The in-traepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science 334, 1293-1297.
    • (2011) Science , vol.334 , pp. 1293-1297
    • Strid, J.1    Sobolev, O.2    Zafirova, B.3    Polic, B.4    Hayday, A.5
  • 75
    • 33846783090 scopus 로고    scopus 로고
    • Skin 7Ô T-cell functions in homeo-stasis and wound healing
    • Jameson, J., Havran, W. L. (2007) Skin 7Ô T-cell functions in homeo-stasis and wound healing. Immunol. Rev. 215, 114-122.
    • (2007) Immunol. Rev , vol.215 , pp. 114-122
    • Jameson, J.1    Havran, W.L.2
  • 76
    • 79952343500 scopus 로고    scopus 로고
    • YS T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody
    • Braza, M. S., Klein, B., Fiol, G., Rossi, J. F. (2011) yS T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody. Haemato-logica 96, 400-407.
    • Haemato-logica , vol.96 , pp. 400-407
    • Braza, M.S.1    Klein, B.2    Fiol, G.3    Rossi, J.4
  • 79
    • 0034660687 scopus 로고    scopus 로고
    • Stimulation of 7Ô T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma
    • Kunzmann, V., Bauer, E., Feurle, J., Weissinger, F., Tony, H. P., Wil-helm, M. (2000) Stimulation of 7Ô T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood 96, 384-392.
    • (2000) Blood , vol.96 , pp. 384-392
    • Kunzmann, V.1    Bauer, E.2    Feurle, J.3    Weissinger, F.4    Tony, H.P.5    Wil-Helm, M.6
  • 82
    • 33846813974 scopus 로고    scopus 로고
    • Safety profile and anti-tumor effects of adoptive immunotherapy using 7Ô T cells against advanced renal cell carcinoma: A pilot study
    • Kobayashi, H., Tanaka, Y, Yagi, J., Osaka, Y, Nakazawa, H., Uchiyama, T., Minato, N., Toma, H. (2007) Safety profile and anti-tumor effects of adoptive immunotherapy using 7Ô T cells against advanced renal cell carcinoma: a pilot study. Cancer Immunol. Immunother. 56, 469-476.
    • (2007) Cancer Immunol. Immunother , vol.56 , pp. 469-476
    • Kobayashi, H.1    Tanaka, Y.2    Yagi, J.3    Osaka, Y.4    Nakazawa, H.5    Uchiyama, T.6    Minato, N.7    Toma, H.8
  • 83
  • 84
    • 41149139540 scopus 로고    scopus 로고
    • Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded V79VÔ2 T cells from renal cell carcinoma patients
    • Viey, E., Lucas, C, Romagne, F., Escudier, B., Chouaib, S., Caignard, A. (2008) Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded V79VÔ2 T cells from renal cell carcinoma patients. J. Immunother. 31, 313-323.
    • (2008) J. Immunother , vol.31 , pp. 313-323
    • Viey, E.1    Lucas, C.2    Romagne, F.3    Escudier, B.4    Chouaib, S.5    Caignard, A.6
  • 85
  • 88
    • 34250207973 scopus 로고    scopus 로고
    • Long term disease-free survival in acute leukemia patients recovering with increased 7Ô T cells after partially mismatched related donor bone marrow transplantation
    • Godder, K. T., Henslee-Downey, P. J., Mehta, J., Park, B. S., Chiang, K Y, Abhyankar, S., Lamb, L. S. (2007) Long term disease-free survival in acute leukemia patients recovering with increased 7Ô T cells after partially mismatched related donor bone marrow transplantation. Bone Marrow Transplant. 39, 751-757.
    • (2007) Bone Marrow Transplant , vol.39 , pp. 751-757
    • Godder, K.T.1    Henslee-Downey, P.J.2    Mehta, J.3    Park, B.S.4    Chiang, K.Y.5    Abhyankar, S.6    Lamb, L.S.7
  • 89
    • 0032610496 scopus 로고    scopus 로고
    • Graft-facilitating doses of ex vivo activated 7Ô T cells do not cause lethal murine graft-vs.-host disease
    • Drobyski, W. R., Majewski, D., Hanson, G. (1999) Graft-facilitating doses of ex vivo activated 7Ô T cells do not cause lethal murine graft-vs.-host disease. Biol. Blood Marrow Transplant. 5, 222-230.
    • (1999) Biol. Blood Marrow Transplant , vol.5 , pp. 222-230
    • Drobyski, W.R.1    Majewski, D.2    Hanson, G.3
  • 92
    • 0028979453 scopus 로고
    • Human V79VÔ2 cells are stimulated in a cross-reactive fashion by a variety of phosphorylated metabolites
    • Burk, M. R, Mori, L., De Libero, G. (1995) Human V79VÔ2 cells are stimulated in a cross-reactive fashion by a variety of phosphorylated metabolites. Eur. J. Immunol. 25, 2052-2058.
    • (1995) Eur. J. Immunol , vol.25 , pp. 2052-2058
    • Burk, M.R.1    Mori, L.2    de Libero, G.3
  • 93
    • 0029073751 scopus 로고
    • Natural and synthetic non-peptide antigens recognized by human 7Ô T cells
    • Tanaka, Y., Morita, C. T., Nieves, E., Brenner, M. B., Bloom, B. R (1995) Natural and synthetic non-peptide antigens recognized by human 7Ô T cells. Nature 375, 155-158.
    • (1995) Nature , vol.375 , pp. 155-158
    • Tanaka, Y.1    Morita, C.T.2    Nieves, E.3    Brenner, M.B.4    Bloom, B.R.5
  • 97
    • 0037455013 scopus 로고    scopus 로고
    • Human T cell receptor 7Ô cells recognize endogenous me-valonate metabolites in tumor cells
    • Gober, H. J., Kistowska, M., Angman, L., Jeno, P., Mori, L., De Libero, G. (2003) Human T cell receptor 7Ô cells recognize endogenous me-valonate metabolites in tumor cells. J. Exp. Med. 197, 163-168.
    • (2003) J. Exp. Med , vol.197 , pp. 163-168
    • Gober, H.J.1    Kistowska, M.2    Angman, L.3    Jeno, P.4    Mori, L.5    de Libero, G.6
  • 98
    • 67649213021 scopus 로고    scopus 로고
    • Reduced expression of the meval-onate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by V79VÔ2 T cells
    • Li, J., Herold, M. J., Kimmel, B., Muller, L, Rincon-Orozco, B., Kunzmann, V-, Herrmann, T. (2009) Reduced expression of the meval-onate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by V79VÔ2 T cells. J. Immunol. 182, 8118-8124.
    • (2009) J. Immunol , vol.182 , pp. 8118-8124
    • Li, J.1    Herold, M.J.2    Kimmel, B.3    Muller, L.4    Rincon-Orozco, B.5    Kunzmann, V.6    Herrmann, T.7
  • 99
    • 58149086028 scopus 로고    scopus 로고
    • Peripheral blood monocytes are responsible for 7Ô T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP
    • Roelofs, A. J., Jauhiainen, M., Monkkonen, H., Rogers, M. J., Monkkonen, J., Thompson, K (2009) Peripheral blood monocytes are responsible for 7Ô T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. Br. J. Haematol. 144, 245-250.
    • (2009) Br. J. Haematol , vol.144 , pp. 245-250
    • Roelofs, A.J.1    Jauhiainen, M.2    Monkkonen, H.3    Rogers, M.J.4    Monkkonen, J.5    Thompson, K.6
  • 101
    • 30444431620 scopus 로고    scopus 로고
    • Alkylamines cause V79VÔ2 T-cell activation and proliferation by inhibiting the mevalonate pathway
    • Thompson, K, Rojas-Navea, J., Rogers, M. J. (2006) Alkylamines cause V79VÔ2 T-cell activation and proliferation by inhibiting the mevalonate pathway. Blood 107, 651-654.
    • (2006) Blood , vol.107 , pp. 651-654
    • Thompson, K.1    Rojas-Navea, J.2    Rogers, M.J.3
  • 102
    • 84874971805 scopus 로고    scopus 로고
    • Human cord blood 7Ô T cells expressing public V72 chains dominate the response to bisphosphonate plus interleukin-15
    • Cairo, C, Sagnia, B., Cappelli, G., Colizzi, V., Leke, R G., Leke, R. J., Pauza, C. D. (2013) Human cord blood 7Ô T cells expressing public V72 chains dominate the response to bisphosphonate plus interleukin-15. Immunology 138, 346-360.
    • (2013) Immunology , vol.138 , pp. 346-360
    • Cairo, C.1    Sagnia, B.2    Cappelli, G.3    Colizzi, V.4    Leke, R.G.5    Leke, R.J.6    Pauza, C.D.7
  • 103
    • 77953646926 scopus 로고    scopus 로고
    • Cytokine requirements for the differentiation and expansion of IL-17A-and IL-22-pro-ducing human V72VÔ2 T cells
    • Ness-Schwickerath, K J., Jin, C, Morita, C. T. (2010) Cytokine requirements for the differentiation and expansion of IL-17A-and IL-22-pro-ducing human V72VÔ2 T cells. J. Immunol. 184, 7268-7280.
    • (2010) J. Immunol , vol.184 , pp. 7268-7280
    • Ness-Schwickerath, K.J.1    Jin, C.2    Morita, C.T.3
  • 104
    • 84880923112 scopus 로고    scopus 로고
    • Y 8 T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK
    • Inatsuka, C, Yang, Y, Gad, E., Rastetter, L., Disis, M. L., Lu, H. (2013) y 8 T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK. Cancer Immunol. Immunother. 62, 1335-1345.
    • Cancer Immunol. Immunother , vol.62 , pp. 1335-1345
    • Inatsuka, C.1    Yang, Y.2    Gad, E.3    Rastetter, L.4    Disis, M.L.5
  • 105
    • 78650399313 scopus 로고    scopus 로고
    • IL-17 production by y8 T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer
    • Takeuchi, A, Dejima, T., Yamada, H., Shibata, K, Nakamura, R, Eto, M., Nakatani, T., Naito, S., Yoshikai, Y (2011) IL-17 production by y8 T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer. Eur. J. Immunol. 41, 246-251.
    • (2011) Eur. J. Immunol , vol.41 , pp. 246-251
    • Takeuchi, A.1    Dejima, T.2    Yamada, H.3    Shibata, K.4    Nakamura, R.5    Eto, M.6    Nakatani, T.7    Naito, S.8    Yoshikai, Y.9
  • 106
    • 78650334358 scopus 로고    scopus 로고
    • CD70-CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human 7Ô peripheral blood lymphocytes
    • DeBarros, A, Chaves-Ferreira, M., d'Orey, F., Ribot, J. C, Silva-Santos, B. (2011) CD70-CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human 7Ô peripheral blood lymphocytes. Eur. J. Immunol. 41, 195-201.
    • (2011) Eur. J. Immunol , vol.41 , pp. 195-201
    • Debarros, A.1    Chaves-Ferreira, M.2    D'Orey, F.3    Ribot, J.C.4    Silva-Santos, B.5
  • 108
    • 11344259248 scopus 로고    scopus 로고
    • Human 7Ô T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation
    • Otto, M., Barfield, R C, Iyengar, R., Gatewood, J., Muller, I., Holladay, M. S., Houston, J., Leung, W., Handgretinger, R (2005) Human 7Ô T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation. J. Immunother. 28, 73-78.
    • (2005) J. Immunother , vol.28 , pp. 73-78
    • Otto, M.1    Barfield, R.C.2    Iyengar, R.3    Gatewood, J.4    Muller, I.5    Holladay, M.S.6    Houston, J.7    Leung, W.8    Handgretinger, R.9
  • 109
    • 28544448891 scopus 로고    scopus 로고
    • Combination immunotherapy with clinical-scale enriched human 7Ô T cells, hul4.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblas-toma
    • Otto, M., Barfield, R C, Martin, W. J., Iyengar, R, Leung, W., Leimig, T., Chaleff, S., Gillies, S. D., Handgretinger, R (2005) Combination immunotherapy with clinical-scale enriched human 7Ô T cells, hul4.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblas-toma. Clin. Cancer Res. 11,8486-8491.
    • (2005) Clin. Cancer Res , vol.11 , pp. 8486-8491
    • Otto, M.1    Barfield, R.C.2    Martin, W.J.3    Iyengar, R.4    Leung, W.5    Leimig, T.6    Chaleff, S.7    Gillies, S.D.8    Handgretinger, R.9
  • 114
  • 118
    • 79960903905 scopus 로고    scopus 로고
    • Phase I/II study of adoptive transfer of 7Ô T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma
    • Kobayashi, H., Tanaka, Y, Yagi, J., Minato, N., Tanabe, K (2011) Phase I/II study of adoptive transfer of 7Ô T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma. Cancer Immunol. Immunother. 60, 1075-1084.
    • (2011) Cancer Immunol. Immunother , vol.60 , pp. 1075-1084
    • Kobayashi, H.1    Tanaka, Y.2    Yagi, J.3    Minato, N.4    Tanabe, K.5
  • 119
    • 67650032911 scopus 로고    scopus 로고
    • Clinical and immunological evaluation of zoledronate-activated V79 7Ô T-cell-based immunotherapy for patients with multiple myeloma
    • Abe, Y, Muto, M., Nieda, M., Nakagawa, Y, Nicol, A, Kaneko, T., Goto, S., Yokokawa, K, Suzuki, K (2009) Clinical and immunological evaluation of zoledronate-activated V79 7Ô T-cell-based immunotherapy for patients with multiple myeloma. Exp. Hematol. 37, 956-968.
    • (2009) Exp. Hematol , vol.37 , pp. 956-968
    • Abe, Y.1    Muto, M.2    Nieda, M.3    Nakagawa, Y.4    Nicol, A.5    Kaneko, T.6    Goto, S.7    Yokokawa, K.8    Suzuki, K.9
  • 122
    • 78650386896 scopus 로고    scopus 로고
    • Zoledronate-activated V79 7Ô T cell-based immunotherapy is feasible and restores the impairment of 7Ô T cells in patients with solid tumors
    • Noguchi, A, Kaneko, T., Kamigaki, T., Fujimoto, K, Ozawa, M., Saito, M., Ariyoshi, N., Goto, S. (2011) Zoledronate-activated V79 7Ô T cell-based immunotherapy is feasible and restores the impairment of 7Ô T cells in patients with solid tumors. Cytotherapy. 13, 92-97.
    • (2011) Cytotherapy , vol.13 , pp. 92-97
    • Noguchi, A.1    Kaneko, T.2    Kamigaki, T.3    Fujimoto, K.4    Ozawa, M.5    Saito, M.6    Ariyoshi, N.7    Goto, S.8
  • 125
    • 22044456043 scopus 로고    scopus 로고
    • Professional antigen-presentation function by human 7Ô T Cells
    • Brandes, M., Willimann, K, Moser, B. (2005) Professional antigen-presentation function by human 7Ô T Cells. Science. 309, 264-268.
    • (2005) Science , vol.309 , pp. 264-268
    • Brandes, M.1    Willimann, K.2    Moser, B.3
  • 127
    • 31144449879 scopus 로고    scopus 로고
    • Potentiation of antigen-stimulated V79VÔ2 T cell cytokine production by immature dendritic cells (DC) and reciprocal effect on DC maturation
    • Devilder, M. C, Maillet, S., Bouyge-Moreau, L, Donnadieu, E., Bonneville, M., Scotet, E. (2006) Potentiation of antigen-stimulated V79VÔ2 T cell cytokine production by immature dendritic cells (DC) and reciprocal effect on DC maturation. J. Immunol. 176, 1386-1393.
    • (2006) J. Immunol , vol.176 , pp. 1386-1393
    • Devilder, M.C.1    Maillet, S.2    Bouyge-Moreau, L.3    Donnadieu, E.4    Bonneville, M.5    Scotet, E.6
  • 128
    • 33947718052 scopus 로고    scopus 로고
    • A tuberculosis vaccine based on phosphoantigens and fusion proteins induces distinct y8 and a/3 T cell responses in primates
    • Cendron, D., Ingoure, S., Martino, A, Casetti, R, Horand, F., Romagne, F., Sicard, H., Fournie, J. J., Poccia, F. (2007) A tuberculosis vaccine based on phosphoantigens and fusion proteins induces distinct y8 and a/3 T cell responses in primates. Eur. J. Immunol. 37, 549-565.
    • (2007) Eur. J. Immunol , vol.37 , pp. 549-565
    • Cendron, D.1    Ingoure, S.2    Martino, A.3    Casetti, R.4    Horand, F.5    Romagne, F.6    Sicard, H.7    Fournie, J.J.8    Poccia, F.9
  • 129
    • 67651087317 scopus 로고    scopus 로고
    • The NKG2D ligand ULBP4 binds to TCR79/Ô2 and induces cytotoxicity to tumor cells through both TCR7Ô and NKG2D
    • Kong, Y., Cao, W., Xi, X., Ma, C, Cui, L., He, W. (2009) The NKG2D ligand ULBP4 binds to TCR79/Ô2 and induces cytotoxicity to tumor cells through both TCR7Ô and NKG2D. Blood. 114, 310-317.
    • (2009) Blood , vol.114 , pp. 310-317
    • Kong, Y.1    Cao, W.2    Xi, X.3    Ma, C.4    Cui, L.5    He, W.6
  • 130
    • 77956032245 scopus 로고    scopus 로고
    • Identification of a panel of ten cell surface protein antigens associated with immunotargeting of leukemias and lymphomas by peripheral blood y8 T cells
    • Gomes, A. Q., Correia, D. V., Grosso, A. R., Lanca, T., Ferreira, C, Lacerda, J. F., Barata, J. T., Silva, M. G., Silva-Santos, B. (2010) Identification of a panel of ten cell surface protein antigens associated with immunotargeting of leukemias and lymphomas by peripheral blood y8 T cells. Haematologica. 95, 1397-1404.
    • (2010) Haematologica , vol.95 , pp. 1397-1404
    • Gomes, A.Q.1    Correia, D.V.2    Grosso, A.R.3    Lanca, T.4    Ferreira, C.5    Lacerda, J.F.6    Barata, J.T.7    Silva, M.G.8    Silva-Santos, B.9
  • 134
    • 84875746357 scopus 로고    scopus 로고
    • Ex vivo characterization of 7Ô T-cell repertoire in patients after adoptive transfer of V79VÔ2 T cells expressing the interleukin-2 receptor /3-chain and the common. chain
    • Izumi, T., Kondo, M., Takahashi, T., Fujieda, N., Kondo, A, Tamura, N., Murakawa, T., Nakajima, J., Matsushita, H., Kakimi, K (2013) Ex vivo characterization of 7Ô T-cell repertoire in patients after adoptive transfer of V79VÔ2 T cells expressing the interleukin-2 receptor /3-chain and the common. chain. Cytotherapy. 15, 481-491.
    • (2013) Cytotherapy , vol.15 , pp. 481-491
    • Izumi, T.1    Kondo, M.2    Takahashi, T.3    Fujieda, N.4    Kondo, A.5    Tamura, N.6    Murakawa, T.7    Nakajima, J.8    Matsushita, H.9    Kakimi, K.10
  • 135
    • 84888779872 scopus 로고    scopus 로고
    • Recombinant human IL-15 promotes in vivo expansion of adoptively transferred NK cells in a first-in-human phase I dose escalation study in patients with AML
    • Cooley, S., Verneris, M. R, Curtsinger, J., McKenna, D., Weisdorf, D. J., Blazar, B. R., Waldmann, T. A, Miller, J. S. (2012) Recombinant human IL-15 promotes in vivo expansion of adoptively transferred NK cells in a first-in-human phase I dose escalation study in patients with AML. Blood. 120, 894.
    • (2012) Blood , vol.120 , pp. 894
    • Cooley, S.1    Verneris, M.R.2    Curtsinger, J.3    McKenna, D.4    Weisdorf, D.J.5    Blazar, B.R.6    Waldmann, T.A.7    Miller, J.S.8
  • 136
    • 79961015575 scopus 로고    scopus 로고
    • Differentiation of human peripheral blood VÔ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells
    • Correia, D. V., Fogli, M., Hudspeth, K, da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011) Differentiation of human peripheral blood VÔ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells. Blood 118, 992-1001.
    • (2011) Blood , vol.118 , pp. 992-1001
    • Correia, D.V.1    Fogli, M.2    Hudspeth, K.3    da Silva, M.G.4    Mavilio, D.5    Silva-Santos, B.6
  • 137
    • 84872225254 scopus 로고    scopus 로고
    • Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors
    • Ni, J., Miller, M., Stojanovic, A, Garbi, N., Cerwenka, A. (2012) Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J. Exp. Med. 209, 2351-2365.
    • (2012) J. Exp. Med , vol.209 , pp. 2351-2365
    • Ni, J.1    Miller, M.2    Stojanovic, A.3    Garbi, N.4    Cerwenka, A.5
  • 141
    • 80051720194 scopus 로고    scopus 로고
    • Chi-meric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter, D. L., Levine, B. L., Kalos, M., Bagg, A., June, C. H. (2011) Chi-meric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Eng. J. Med. 365, 725-733.
    • (2011) N. Eng. J. Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 143
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos, M., Levine, B. L., Porter, D. L., Katz, S., Grupp, S. A., Bagg, A., June, C. H. (2011) T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Science translational medicine. 3, 95ra73.
    • (2011) Science Translational Medicine , vol.3
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3    Katz, S.4    Grupp, S.A.5    Bagg, A.6    June, C.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.