A large-scale method for the selective depletion of αβ T lymphocytes from PBSC for allogeneic transplantation

Cytotherapy

Volumn 9, Issue 8, 2007, Pages 746-754

  Chaleff, S ^a   Otto, M ^a   Barfield, R C ^a   Leimig, T ^a   Iyengar, R ^a   Martin, J ^a   Holiday, M ^a   Houston, J ^a   Geiger, T ^a   Huppert, V ^b   Handgretinger, R ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b MILTENYI BIOTEC GMBH   (Germany)

Author keywords

Allogeneic transplantation; Natural killer cells; Peripheral mobilized stem cells; T cell depletion; T lymphocytes

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR;

ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ARTICLE; BIOTINYLATION; CELL CULTURE; CELL SPECIFICITY; COLONY FORMING UNIT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; KNOCKOUT MOUSE; LEUKAPHERESIS; MEDICAL INSTRUMENTATION; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SCID MOUSE; STEM CELL MOBILIZATION; T CELL DEPLETION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 36849036501     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240701644000     Document Type: Article

References (34)

1. Filipovich, AH, McGlave, P. and Ramsay, NK (1982) Treatment of donor bone marrow with OKT3 (PAN-T monoclonal antibody) for prophylaxis of graft-vs.-host disease (GvHD) in histocompatible allogeneic bone marrow transplantation (BMT): A pilot study. J Clin Immunol, 2, pp. 154S-7S.
2. Filipovich, AH, Vallera, DA and Youle, RJ (1987) Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow. Transplantation, 44, pp. 62-69.
3. Martin, PJ, Hansen, JA and Torok-Storb, B. (1988) Effects of treating marrow with a CD3-specific immunotoxin for prevention of acute graft-versus-host disease. Bone Marrow Transplant, 3, pp. 437-444.
4. + cells using the CliniMACS device. J Hematother, 8, pp. 209-218.
5. + progenitors for autologous and allogeneic transplantation in children. Bone Marrow Transplant, 24, pp. 583-589.
6. Handgretinger, R., Klingebiel, T. and Lang, P. (2001) Megadose transplantation of purified peripheral blood CD34(+) progenitor cells from HLA-mismatched parental donors in children. Bone Marrow Transplant, 27, pp. 777-783.
7. + selected hematopoietic cells: clinical problems and current challenges. Leuk Lymphoma, 45, pp. 447-453.
8. Horowitz, MM, Gale, RP and Sondel, PM (1990) Graft-versus-leukemia reactions after bone marrow transplantation. Blood, 75, pp. 555-562.
9. Ruggeri, L., Mancusi, A. and Capanni, M. (2005) Exploitation of alloreactive NK cells in adoptive immunotherapy of cancer. Curr Opin Immunol, 17, pp. 211-217.
10. Gordon, PR, Leimig, T. and Mueller, I. (2002) A large-scale method for T cell depletion: Towards graft engineering of mobilized peripheral blood stem cells. Bone Marrow Transplant, 30, pp. 69-74.
11. Benaim, E., Hale, G. and Horwitz, EM (2005) Reduced-intensity conditioning (RIC) in haploidentical transplantation [abstract]. Blood, p. 104.
12. Doherty, PC. (1992) The function of gamma delta T cells. Br J Haematol, 81, pp. 321-324.
13. Drobyski, WR, Majewski, D. and Hanson, G. (1999) Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease. Biol Blood Marrow Transplant, 5, pp. 222-230.
14. + T cells in disease-free survivors following T cell-depleted, partially mismatched, related donor bone marrow transplantation for leukemia. J Hematother, 5, pp. 503-509.
15. Schilbach, K., Geiselhart, A. and Handgretinger, R. (2001) Induction of proliferation and augmented cytotoxicity of gammadelta T lymphocytes by bisphosphonate clodronate. Blood, 97, pp. 2917-2918.
16. Blazar, BR, Taylor, PA, Bluestone, JA and Vallera, DA. (1996) Murine gamma/delta-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens. Blood, 87, pp. 4463-4472.
17. Shultz, LD, Lyons, BL and Burzenski, LM (2005) Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R{gamma}null mice engrafted with mobilized human hemopoietic stem cells. J Immunol, 174, pp. 6477-6489.
18. Ho, VT and Soiffer, RJ. (2001) The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood, 98, pp. 3192-3204.
19. + progenitor cells from related and unrelated donors in children with nonmalignant diseases. Bone Marrow Transplant, 33, pp. 25-32.
20. Barfield, RC, Otto, M. and Houston, J. (2004) A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation. Cytotherapy, 6, pp. 1-6.
21. Sims-Poston, L., Handgretinger, R. and Eldridge, PW. (2005) Graft composition of Clinimacs system T-cell depleted HPC-A used for transplant [abstract]. Cytotherapy, 5, p. 35.
22. Leung, W., Iyengar, R. and Turner, V. (2004) Determinants of antileukemia effects of allogeneic NK cells. J Immunol, 172, pp. 644-650.
23. Ruggeri, L., Capanni, M. and Urbani, E. (2002) Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science, 295, pp. 2097-2100.
24. Uffermann-Gretzinger, S., Lossos, IS and Vayntrub, TA (2002) Rapid establishment of dendritic cell chimerism in allogeneic hematopoietic cell transplant recipients. Blood, 99, pp. 1442-1448.
25. Lamb Jr, LS and Lopez, RD. (2005) Gammadelta T cells: A new frontier for immunotherapy?. Biol Blood Marrow Transplant, 11, pp. 161-168.
26. Champlin, RE, Passweg, JR and Zhang, MJ (2000) T-cell depletion of bone marrow transplants for leukemia from donors other than HLA-identical siblings: Advantage of T-cell antibodies with narrow specificities. Blood, 95, pp. 3996-4003.
27. Keever-Taylor, CA, Craig, A. and Molter, M. (2001) Complement-mediated T-cell depletion of bone marrow: Comparison of T10B9.1A-31 and Muromonab-Orthoclone OKT3. Cytotherapy, 3, pp. 467-481.
28. Borst, J., van Dongen, JJ and de Vries, E. (1990) BMA031, a monoclonal antibody suited to identify the T-cell receptor alpha beta/CD3 complex on viable human T lymphocytes in normal and disease states. Hum Immunol, 29, pp. 175-188.
29. Borst, J., van Dongen, JJ and Devries, E. (1990) BMA031 a monoclonal antibody suited to identify the T-cell receptor alpha beta/CD3 complex on viable human T lymphocytes in normal and disease states. Hum Immunol, 29, pp. 175-188.
30. Hebart, H., Ehninger, G. and Schmidt, H. (1995) Treatment of steroid-resistant graft-versus-host disease after allogeneic bone marrow transplantation with anti-CD3/TCR monoclonal antibodies. Bone Marrow Transplant, 15, pp. 891-894.
31. Otto, M., Barfield, RC and Iyengar, R. (2005) Human gammadelta T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation. J Immunother, 28, pp. 73-78.
32. Kunzmann, V., Bauer, E. and Feurle, J. (2000) Stimulation of gammadelta T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood, 96, pp. 384-392.
33. Wilhelm, M., Kunzmann, V. and Eckstein, S. (2003) Gammadelta T cells for immune therapy of patients with lymphoid malignancies. Blood, 102, pp. 200-206.
34. Miller, JS, Soignier, Y. and Panoskaltsis-Mortari, A. (2005) Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood, 105, pp. 3051-3057.