Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 85, Issue 3 PART A, 2013, Pages 390-397

  Aranda, Cristina ^a   Urbiola, Koldo ^a   Méndez Ardoy, Alejandro ^b   García Fernández, José M ^c   Ortiz Mellet, Carmen ^b   De Ilarduya, Conchita Tros ^a,b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c CSIC   (Spain)

Author keywords

Folate receptors; Folic acid; Gene delivery; Nanomedicine; Pharmaceutics; Polycationic amphiphilic cyclodextrins

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLODEXTRIN DERIVATIVE; FOLATE RECEPTOR; FOLIC ACID; LUCIFERASE ENCODING PLASMID DNA; NAKED DNA; PE125 LUCIFERASE ENCODING PLASMID DNA; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL VIABILITY; CONTROLLED STUDY; COVALENT BOND; DRUG DISTRIBUTION; DRUG FORMULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO GENE TRANSFER; IN VIVO STUDY; LARGE SCALE PRODUCTION; LUNG; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; REPORTER GENE; ZETA POTENTIAL;

FOLATE RECEPTORS; FOLIC ACID; GENE DELIVERY; NANOMEDICINE; PHARMACEUTICS; POLYCATIONIC AMPHIPHILIC CYCLODEXTRINS;

CYCLODEXTRINS; DNA; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC THERAPY; HELA CELLS; HEP G2 CELLS; HUMANS; LIVER; LUCIFERASES; LUNG; NANOPARTICLES; PLASMIDS; POLYAMINES; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 84888371527     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.06.011     Document Type: Article

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