메뉴 건너뛰기




Volumn 16, Issue 3, 1998, Pages 205-219

The folate receptor as a potential therapeutic anticancer target

Author keywords

Antifolate drug therapy; Folate receptor; Immunotherapy; Potocytosis

Indexed keywords

10 PROPARGYL 5,8 DIDEAZAFOLIC ACID; AG 2032; ANTINEOPLASTIC AGENT; FOLIC ACID; FOLIC ACID ANTAGONIST; FOLIC ACID DERIVATIVE; LOMETREXOL; MONOCLONAL ANTIBODY; N [5 [2 (2 AMINO 1,4,5,6,7,8 HEXAHYDRO 4 OXOPYRIDO[2,3 D]PYRIMIDIN 6 YL)ETHYL] 2 THENOYL]GLUTAMIC ACID; N [[5 [2 (2 AMINO 4,6,7,8 TETRAHYDRO 4 OXO 1H PYRIMIDO[5,4 B][1,4]THIAZIN 6 YL)ETHYL] 2 THIENYL]CARBONYL]GLUTAMIC ACID; PLEVITREXED; RALTITREXED; RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 0032427784     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006147932159     Document Type: Review
Times cited : (55)

References (97)
  • 1
    • 0029818146 scopus 로고    scopus 로고
    • Folate receptors
    • Antony AC: Folate receptors. Annu Rev Nutr 16: 501-521, 1996
    • (1996) Annu Rev Nutr , vol.16 , pp. 501-521
    • Antony, A.C.1
  • 2
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson RGW, Kamen BA, Rothberg KG, Lacey SW: Potocytosis: sequestration and transport of small molecules by caveolae. Science 255: 410-411, 1992
    • (1992) Science , vol.255 , pp. 410-411
    • Anderson, R.G.W.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 3
    • 0025951931 scopus 로고
    • Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis
    • Leamon CP, Low PS: Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc Natl Acad Sci USA 88: 5572-5576, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5572-5576
    • Leamon, C.P.1    Low, P.S.2
  • 7
    • 0023950855 scopus 로고
    • Human ovarian carcinoma lysis by cytotoxic T cells targeted by bispecific monoclonal antibodies: Analysis of the antibody components
    • Mezzanzanica D, Canevari S, Menard S, Pupa SM, Tagliabue E, Lanzavecchia A, Colnaghi MI: Human ovarian carcinoma lysis by cytotoxic T cells targeted by bispecific monoclonal antibodies: analysis of the antibody components. Int J Cancer 41: 609-615, 1988
    • (1988) Int J Cancer , vol.41 , pp. 609-615
    • Mezzanzanica, D.1    Canevari, S.2    Menard, S.3    Pupa, S.M.4    Tagliabue, E.5    Lanzavecchia, A.6    Colnaghi, M.I.7
  • 8
    • 0028267011 scopus 로고
    • A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors
    • Habeck LL, Leitner TA, Shackelford KA, Gossett LS, Schultz RM, Andis SL, Shih C, Grindey GB, Mendelsohn LG: A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res 54: 1021-1026, 1994
    • (1994) Cancer Res , vol.54 , pp. 1021-1026
    • Habeck, L.L.1    Leitner, T.A.2    Shackelford, K.A.3    Gossett, L.S.4    Schultz, R.M.5    Andis, S.L.6    Shih, C.7    Grindey, G.B.8    Mendelsohn, L.G.9
  • 9
    • 0029802509 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol
    • Mendelsohn LG, Shih C, Schultz RM, Worzalla JF: Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol. Invest New Drugs 14: 287-294, 1996
    • (1996) Invest New Drugs , vol.14 , pp. 287-294
    • Mendelsohn, L.G.1    Shih, C.2    Schultz, R.M.3    Worzalla, J.F.4
  • 11
    • 0007468491 scopus 로고    scopus 로고
    • Low serum-folic-acid in malignancy
    • Magnus EM: Low serum-folic-acid in malignancy. Lancet 1963: 302
    • Lancet , vol.1963 , pp. 302
    • Magnus, E.M.1
  • 13
    • 0014061228 scopus 로고
    • Folate activity in serum and red cells of patients with cancer
    • Magnus EM: Folate activity in serum and red cells of patients with cancer. Cancer Res 27: 490-497, 1967
    • (1967) Cancer Res , vol.27 , pp. 490-497
    • Magnus, E.M.1
  • 14
    • 0014733562 scopus 로고
    • A macromolecular factor in some leukemic cells which binds folic acid
    • Rothenberg SP: A macromolecular factor in some leukemic cells which binds folic acid. Proc Soc Exp Biol Med 133: 428-432, 1970
    • (1970) Proc Soc Exp Biol Med , vol.133 , pp. 428-432
    • Rothenberg, S.P.1
  • 15
    • 0015023980 scopus 로고
    • Further observations on the folate-binding factor in some leukemic cells
    • Rothenberg SP, daCosta M: Further observations on the folate-binding factor in some leukemic cells. J Clin Invest 50: 719-726, 1971
    • (1971) J Clin Invest , vol.50 , pp. 719-726
    • Rothenberg, S.P.1    DaCosta, M.2
  • 17
    • 0025740371 scopus 로고
    • The conversion of the human membrane-associated folate-binding protein (folate receptor) to the soluble folate-binding protein by a membrane-associated metalloprotease
    • Elwood PC, Deutsch JC, Kolhouse JF: The conversion of the human membrane-associated folate-binding protein (folate receptor) to the soluble folate-binding protein by a membrane-associated metalloprotease. J Biol Chem 266: 2346-2353, 1991
    • (1991) J Biol Chem , vol.266 , pp. 2346-2353
    • Elwood, P.C.1    Deutsch, J.C.2    Kolhouse, J.F.3
  • 18
    • 0022289620 scopus 로고
    • Folate-binding protein and the estrogen receptor in breast cancer
    • Rochman H, Selhub J, Karrison T: Folate-binding protein and the estrogen receptor in breast cancer. Cancer Detect Prev 8: 71-75, 1985
    • (1985) Cancer Detect Prev , vol.8 , pp. 71-75
    • Rochman, H.1    Selhub, J.2    Karrison, T.3
  • 21
    • 0028148692 scopus 로고
    • The folate receptor in central nervous system malignancies of childhood
    • Weitman SD, Frazier KM, Kamen BA: The folate receptor in central nervous system malignancies of childhood. J Neuro-Oncol 21: 107-112, 1994
    • (1994) J Neuro-Oncol , vol.21 , pp. 107-112
    • Weitman, S.D.1    Frazier, K.M.2    Kamen, B.A.3
  • 22
    • 0024415796 scopus 로고
    • Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells
    • Elwood PC: Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells. J Biol Chem 264: 14893-14901, 1989
    • (1989) J Biol Chem , vol.264 , pp. 14893-14901
    • Elwood, P.C.1
  • 23
    • 0024336971 scopus 로고
    • Complementary DNA for the folate-binding protein correctly predicts anchoring to the membrane by glycosylphosphatidylinositol
    • Lacey SW, Sanders JM, Rothberg KG, Anderson RGW, Kamen BA: Complementary DNA for the folate-binding protein correctly predicts anchoring to the membrane by glycosylphosphatidylinositol. J Clin Invest 84: 715-720, 1989
    • (1989) J Clin Invest , vol.84 , pp. 715-720
    • Lacey, S.W.1    Sanders, J.M.2    Rothberg, K.G.3    Anderson, R.G.W.4    Kamen, B.A.5
  • 24
    • 0024440701 scopus 로고
    • Homologous membrane folate-binding proteins in human placenta: Cloning and sequence of a cDNA
    • Ratnam M, Marquardt H, Duhring JL, Freisheim JH: Homologous membrane folate-binding proteins in human placenta: cloning and sequence of a cDNA. Biochemistry 28: 8249-8254, 1989
    • (1989) Biochemistry , vol.28 , pp. 8249-8254
    • Ratnam, M.1    Marquardt, H.2    Duhring, J.L.3    Freisheim, J.H.4
  • 25
    • 0026481219 scopus 로고
    • Genomic organization of the human folate receptor genes on chromosome 11q13
    • Ragoussis J, Senger G, Trowsdale J, Campbell IG: Genomic organization of the human folate receptor genes on chromosome 11q13. Genomics 14: 423-430, 1992
    • (1992) Genomics , vol.14 , pp. 423-430
    • Ragoussis, J.1    Senger, G.2    Trowsdale, J.3    Campbell, I.G.4
  • 28
    • 0027204595 scopus 로고
    • Mapping genes according to their amplification status in tumor cells: Contribution to the map of 11q13
    • Szepetowski P, Perucca-Lostanlen D, Gaudray P: Mapping genes according to their amplification status in tumor cells: contribution to the map of 11q13. Genomics 16: 745-750, 1993
    • (1993) Genomics , vol.16 , pp. 745-750
    • Szepetowski, P.1    Perucca-Lostanlen, D.2    Gaudray, P.3
  • 31
    • 0027931489 scopus 로고
    • UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor
    • Orr RE, Kamen BA: UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor. Cancer Res 54: 3905-3911, 1994
    • (1994) Cancer Res , vol.54 , pp. 3905-3911
    • Orr, R.E.1    Kamen, B.A.2
  • 32
    • 0028850829 scopus 로고
    • Identification of a point mutation in the folate receptor gene that confers a dominant negative phenotype
    • Orr RE, Kamen BA: Identification of a point mutation in the folate receptor gene that confers a dominant negative phenotype. Cancer Res 55: 847-852, 1995
    • (1995) Cancer Res , vol.55 , pp. 847-852
    • Orr, R.E.1    Kamen, B.A.2
  • 33
    • 0031010021 scopus 로고    scopus 로고
    • Identification of amino acid residues that determine the differential ligand specificities of folate receptors α and β
    • Shen F, Zheng X, Wang J, Ratnam M: Identification of amino acid residues that determine the differential ligand specificities of folate receptors α and β. Biochemistry 36: 6157-6163, 1997
    • (1997) Biochemistry , vol.36 , pp. 6157-6163
    • Shen, F.1    Zheng, X.2    Wang, J.3    Ratnam, M.4
  • 34
    • 0019305850 scopus 로고
    • Three-dimensional molecular modeling and drug design
    • Gund P, Andose JD, Rhodes JB, Smith GM: Three-dimensional molecular modeling and drug design. Science 208: 1425-1431, 1980.
    • (1980) Science , vol.208 , pp. 1425-1431
    • Gund, P.1    Andose, J.D.2    Rhodes, J.B.3    Smith, G.M.4
  • 36
    • 0026446685 scopus 로고
    • Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates
    • Wang X, Shen F, Freisheim JH, Gentry LE, Ratnam M: Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates. Biochem Pharmacol 44: 1898-1901, 1992
    • (1992) Biochem Pharmacol , vol.44 , pp. 1898-1901
    • Wang, X.1    Shen, F.2    Freisheim, J.H.3    Gentry, L.E.4    Ratnam, M.5
  • 38
    • 0030062634 scopus 로고    scopus 로고
    • Role of membrane folate-binding protein in the cytotoxicity of 5,10-dideazatetrahydrofolic acid in human ovarian carcinoma cell lines in vitro
    • Sen S, Erba E, D'Incalci M, Bottero F, Canevari S, Tomassetti A: Role of membrane folate-binding protein in the cytotoxicity of 5,10-dideazatetrahydrofolic acid in human ovarian carcinoma cell lines in vitro. Br J Cancer 73: 525-530, 1996
    • (1996) Br J Cancer , vol.73 , pp. 525-530
    • Sen, S.1    Erba, E.2    D'Incalci, M.3    Bottero, F.4    Canevari, S.5    Tomassetti, A.6
  • 39
    • 6544276693 scopus 로고    scopus 로고
    • Membrane transport and biological activity of stereoisomers AG2032 and AG2034: Novel inhibitors of glycinamide ribonucleotide formyltransferase
    • Amsterdam, June 16-19
    • Jansen G, Peters GJ, Kathmann I, Boritzki TJ, Jackson RC: Membrane transport and biological activity of stereoisomers AG2032 and AG2034: novel inhibitors of glycinamide ribonucleotide formyltransferase (abstr). 10th NCI-EORTC Symposium on New Drugs in Cancer Therapy, Amsterdam, June 16-19, 1998
    • (1998) 10th NCI-EORTC Symposium on New Drugs in Cancer Therapy
    • Jansen, G.1    Peters, G.J.2    Kathmann, I.3    Boritzki, T.J.4    Jackson, R.C.5
  • 40
    • 9844255823 scopus 로고    scopus 로고
    • Super in vitro synergy between trimetrexate and the polyglutamylatable antifolates AG2034, AG2032, AG2009 and Tomudex against human HCT-8 colon cells
    • abstr
    • Faessel H, Slocum HK, Jackson RC, Boritzki TJ, Rustum YM, Greco WR: Super in vitro synergy between trimetrexate and the polyglutamylatable antifolates AG2034, AG2032, AG2009 and Tomudex against human HCT-8 colon cells. Proc Am Assoc Cancer Res 37: 385 (abstr), 1996
    • (1996) Proc Am Assoc Cancer Res , vol.37 , pp. 385
    • Faessel, H.1    Slocum, H.K.2    Jackson, R.C.3    Boritzki, T.J.4    Rustum, Y.M.5    Greco, W.R.6
  • 42
    • 0028986856 scopus 로고
    • Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
    • Spinella MJ, Brigle KE, Sierra EE, Goldman ID: Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J Biol Chem 270: 7842-7849, 1995
    • (1995) J Biol Chem , vol.270 , pp. 7842-7849
    • Spinella, M.J.1    Brigle, K.E.2    Sierra, E.E.3    Goldman, I.D.4
  • 45
    • 0029883293 scopus 로고    scopus 로고
    • Augmentation of the therapeutic activity of Lometrexol [(6-R)5,10-dideazatetrahydrofolate] by oral folic acid
    • Alati T, Worzalla JF, Shih C, Bewley JR, Lewis S, Moran RG, Grindey GB: Augmentation of the therapeutic activity of Lometrexol [(6-R)5,10-dideazatetrahydrofolate] by oral folic acid. Cancer Res 56: 2331-2335, 1996
    • (1996) Cancer Res , vol.56 , pp. 2331-2335
    • Alati, T.1    Worzalla, J.F.2    Shih, C.3    Bewley, J.R.4    Lewis, S.5    Moran, R.G.6    Grindey, G.B.7
  • 47
    • 0009180212 scopus 로고    scopus 로고
    • Antitumor therapeutic index of LY309887 is improved with increased folic acid supplementation in mice maintained on a folate-deficient diet
    • abstr
    • Worzalla JF, Self TD, Theobald KS, Rutherford PG, Gossett LS, Shih C, Mendelsohn LG: Antitumor therapeutic index of LY309887 is improved with increased folic acid supplementation in mice maintained on a folate-deficient diet. Proc Am Assoc Cancer Res 37: 383 (abstr), 1996
    • (1996) Proc Am Assoc Cancer Res , vol.37 , pp. 383
    • Worzalla, J.F.1    Self, T.D.2    Theobald, K.S.3    Rutherford, P.G.4    Gossett, L.S.5    Shih, C.6    Mendelsohn, L.G.7
  • 49
    • 0031052281 scopus 로고    scopus 로고
    • Folate-based thymidylate synthase inhibitors in cancer chemotherapy
    • Takemura Y, Jackman AL: Folate-based thymidylate synthase inhibitors in cancer chemotherapy. Anticancer Drugs 8: 3-16, 1997
    • (1997) Anticancer Drugs , vol.8 , pp. 3-16
    • Takemura, Y.1    Jackman, A.L.2
  • 50
    • 0029658045 scopus 로고    scopus 로고
    • Tomudex (ZD1694): From concept to care, a programme in rational drug discovery
    • Jackman AL, Boyle FT, Harrap KR: Tomudex (ZD1694): from concept to care, a programme in rational drug discovery. Invest New Drugs 14: 305-316, 1996
    • (1996) Invest New Drugs , vol.14 , pp. 305-316
    • Jackman, A.L.1    Boyle, F.T.2    Harrap, K.R.3
  • 55
    • 9344267746 scopus 로고    scopus 로고
    • A phase n study in advanced breast cancer: ZD1694 ('Tomudex') a novel direct and specific thymidylate synthase inhibitor
    • Hatschek T, Wilking N, Zalcberg J, Spiers J, Seymour L: A phase n study in advanced breast cancer: ZD1694 ('Tomudex') a novel direct and specific thymidylate synthase inhibitor. Br J Cancer 74: 479-481, 1996
    • (1996) Br J Cancer , vol.74 , pp. 479-481
    • Hatschek, T.1    Wilking, N.2    Zalcberg, J.3    Spiers, J.4    Seymour, L.5
  • 57
    • 0003387879 scopus 로고    scopus 로고
    • Phase I trial of ZD9331, a non-polyglutamatable thymidylate synthase inhibitor given as a five-day continuous infusion
    • abstr
    • Rees C, Judson I, Beale P, Mitchell F, Smith R, Mayne K, Averbuch S, Jackman A: Phase I trial of ZD9331, a non-polyglutamatable thymidylate synthase inhibitor given as a five-day continuous infusion. Proc Am Soc Clin Oncol 16: 208 (abstr), 1997
    • (1997) Proc Am Soc Clin Oncol , vol.16 , pp. 208
    • Rees, C.1    Judson, I.2    Beale, P.3    Mitchell, F.4    Smith, R.5    Mayne, K.6    Averbuch, S.7    Jackman, A.8
  • 59
    • 0000405942 scopus 로고    scopus 로고
    • Addition of Herceptin (humanized anti-her2 antibody) to first line chemotherapy for her2 overexpressing metastatic breast cancer (her2+/MBC) markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • abstr
    • Slamon D, Leyland-Jones B, Shak S, Paton V, Bajamonde A, Fleming T, Eiermann W, Wolter J, Baselga J, Norton L: Addition of Herceptin (humanized anti-her2 antibody) to first line chemotherapy for her2 overexpressing metastatic breast cancer (her2+/MBC) markedly increases anticancer activity: a randomized, multinational controlled phase III trial. Proc Am Soc Clin Oncol 17: 98 (abstr), 1998
    • (1998) Proc Am Soc Clin Oncol , vol.17 , pp. 98
    • Slamon, D.1    Leyland-Jones, B.2    Shak, S.3    Paton, V.4    Bajamonde, A.5    Fleming, T.6    Eiermann, W.7    Wolter, J.8    Baselga, J.9    Norton, L.10
  • 60
    • 0027406702 scopus 로고
    • Trophoblast and ovarian cancer antigen LK26: Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein
    • Garin-Chesa P, Campbell I, Saigo PE, Lewis JL, Old LJ, Rettig WJ: Trophoblast and ovarian cancer antigen LK26: sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am J Pathol 142: 557-567, 1993
    • (1993) Am J Pathol , vol.142 , pp. 557-567
    • Garin-Chesa, P.1    Campbell, I.2    Saigo, P.E.3    Lewis, J.L.4    Old, L.J.5    Rettig, W.J.6
  • 61
    • 0028301692 scopus 로고
    • Chimeric murine-human antibodies directed against folate-binding receptor are efficient mediators of ovarian carcinoma cell killing
    • Coney LR, Mezzanzanica D, Sanborn D, Casalini P, Colnaghi MI, Zurawski VR: Chimeric murine-human antibodies directed against folate-binding receptor are efficient mediators of ovarian carcinoma cell killing. Cancer Res 54: 2448-2455, 1994
    • (1994) Cancer Res , vol.54 , pp. 2448-2455
    • Coney, L.R.1    Mezzanzanica, D.2    Sanborn, D.3    Casalini, P.4    Colnaghi, M.I.5    Zurawski, V.R.6
  • 65
    • 0029035763 scopus 로고
    • Single-dose intraperitoneal radioimmunotherapy with the murine monoclonal antibody I-131 MOv18: Clinical results in patients with minimal residual disease of ovarian cancer
    • Crippa F, Bolis G, Seregni E, Gavoni N, Scarfone G, Ferraris C, Buraggi GL, Bombardieri E: Single-dose intraperitoneal radioimmunotherapy with the murine monoclonal antibody I-131 MOv18: clinical results in patients with minimal residual disease of ovarian cancer. Eur J Cancer 31A: 686-690, 1995
    • (1995) Eur J Cancer , vol.31 A , pp. 686-690
    • Crippa, F.1    Bolis, G.2    Seregni, E.3    Gavoni, N.4    Scarfone, G.5    Ferraris, C.6    Buraggi, G.L.7    Bombardieri, E.8
  • 70
    • 0028947838 scopus 로고
    • Inhibition of bispecific monoclonal antibody (bsAb)-targeted cytolysis by human-anti-mouse antibodies in ovarian carcinoma patients treated with bsAb-targeted activated T-lymphocytes
    • Lamers CHJ, Gratama JW, Warnaar SO, Stoter G, Bolhuis RLH: Inhibition of bispecific monoclonal antibody (bsAb)-targeted cytolysis by human-anti-mouse antibodies in ovarian carcinoma patients treated with bsAb-targeted activated T-lymphocytes. Int J Cancer 60: 450-457, 1995
    • (1995) Int J Cancer , vol.60 , pp. 450-457
    • Lamers, C.H.J.1    Gratama, J.W.2    Warnaar, S.O.3    Stoter, G.4    Bolhuis, R.L.H.5
  • 71
    • 0030773742 scopus 로고    scopus 로고
    • Chimeric bispecific OC/TR monoclonal antibody mediates lysis of tumor cells expressing the folate-binding protein (MOv18) and displays decreased immunogenicity in patients
    • Luiten RM, Warnaar SO, Sanborn D, Lamers CHJ, Bolhuis RLH, Litvinov SV, Zurawski VR, Coney LR: Chimeric bispecific OC/TR monoclonal antibody mediates lysis of tumor cells expressing the folate-binding protein (MOv18) and displays decreased immunogenicity in patients. J Immunother 20: 496-504, 1997
    • (1997) J Immunother , vol.20 , pp. 496-504
    • Luiten, R.M.1    Warnaar, S.O.2    Sanborn, D.3    Lamers, C.H.J.4    Bolhuis, R.L.H.5    Litvinov, S.V.6    Zurawski, V.R.7    Coney, L.R.8
  • 72
    • 0030466658 scopus 로고    scopus 로고
    • CD3-CD28 costimulation as a means to avoiding T cell preactivation in bispecific monoclonal antibody-based treatment of ovarian carcinoma
    • Mazzoni A, Mezzanzanica D, Jung G, Wolf H, Colnaghi MI, Canevari S: CD3-CD28 costimulation as a means to avoiding T cell preactivation in bispecific monoclonal antibody-based treatment of ovarian carcinoma. Cancer Res 56: 5443-5449, 1996
    • (1996) Cancer Res , vol.56 , pp. 5443-5449
    • Mazzoni, A.1    Mezzanzanica, D.2    Jung, G.3    Wolf, H.4    Colnaghi, M.I.5    Canevari, S.6
  • 73
    • 0029073423 scopus 로고
    • Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate receptor-positive tumor cells for lysis
    • Kranz DM, Patrick TA, Brigle KE, Spinella MJ, Roy EJ: Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate receptor-positive tumor cells for lysis. Proc Natl Acad Sci USA 92: 9057-9061, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9057-9061
    • Kranz, D.M.1    Patrick, T.A.2    Brigle, K.E.3    Spinella, M.J.4    Roy, E.J.5
  • 74
    • 0031149555 scopus 로고    scopus 로고
    • Single-chain Fv/folate conjugates mediate efficient lysis of folate receptor-positive tumor cells
    • Cho BK, Roy EJ, Patrick TA, Kranz DM: Single-chain Fv/folate conjugates mediate efficient lysis of folate receptor-positive tumor cells. Bioconjug Chem 8: 338-346, 1997
    • (1997) Bioconjug Chem , vol.8 , pp. 338-346
    • Cho, B.K.1    Roy, E.J.2    Patrick, T.A.3    Kranz, D.M.4
  • 75
    • 0031780611 scopus 로고    scopus 로고
    • Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate
    • Roy EJ, Cho BK, Rund LA, Patrick TA, Kranz DM: Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate. Int J Cancer 76: 761-766, 1998
    • (1998) Int J Cancer , vol.76 , pp. 761-766
    • Roy, E.J.1    Cho, B.K.2    Rund, L.A.3    Patrick, T.A.4    Kranz, D.M.5
  • 78
    • 0026496180 scopus 로고
    • Cytotoxicity of momordin-folate conjugates in cultured human cells
    • Leamon CP, Low PS: Cytotoxicity of momordin-folate conjugates in cultured human cells. J Biol Chem 267: 24966-24971, 1992
    • (1992) J Biol Chem , vol.267 , pp. 24966-24971
    • Leamon, C.P.1    Low, P.S.2
  • 79
    • 0027423248 scopus 로고
    • Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells: Contribution of translocation domain
    • Leamon CP, Pastan I, Low PS: Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells: contribution of translocation domain. J Biol Chem 268: 24847-24854, 1993
    • (1993) J Biol Chem , vol.268 , pp. 24847-24854
    • Leamon, C.P.1    Pastan, I.2    Low, P.S.3
  • 80
    • 0028794831 scopus 로고
    • Folate-mediated tumor cell targeting of liposome-entrapped dorubicin in vitro
    • Lee RJ, Low PS: Folate-mediated tumor cell targeting of liposome-entrapped dorubicin in vitro. Biochim Biophys Acta 1233: 134-144, 1995
    • (1995) Biochim Biophys Acta , vol.1233 , pp. 134-144
    • Lee, R.J.1    Low, P.S.2
  • 83
    • 0030163022 scopus 로고    scopus 로고
    • Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of Gallium-67-deferoxamine-folate
    • Mathias CJ, Wang S, Lee RJ, Waters DJ, Low PS, Green MA: Tumor-selective radiopharmaceutical targeting via receptor-mediated endocytosis of Gallium-67-deferoxamine-folate. J Nucl Med 37: 1003-1008, 1996
    • (1996) J Nucl Med , vol.37 , pp. 1003-1008
    • Mathias, C.J.1    Wang, S.2    Lee, R.J.3    Waters, D.J.4    Low, P.S.5    Green, M.A.6
  • 85
    • 0000630588 scopus 로고
    • Imaging of folate receptors with I-125 labeled folate using small animal imaging system built with plastic scintillating optical fibers
    • abstr
    • Antich P, Kulkarni PV, Constantinescu A, Prior J, Nguyen T, Anderson J, Weitman S, Kamen B, Parkey RW: Imaging of folate receptors with I-125 labeled folate using small animal imaging system built with plastic scintillating optical fibers. J Nucl Med 35: 222 (abstr), 1994
    • (1994) J Nucl Med , vol.35 , pp. 222
    • Antich, P.1    Kulkarni, P.V.2    Constantinescu, A.3    Prior, J.4    Nguyen, T.5    Anderson, J.6    Weitman, S.7    Kamen, B.8    Parkey, R.W.9
  • 86
    • 0028220371 scopus 로고
    • Inhibition of leukaemia cell proliferation by folic acid-polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells
    • Citro G, Szczylik C, Ginobbi P, Zupi G, Calabretta B: Inhibition of leukaemia cell proliferation by folic acid-polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells. Br J Cancer 69: 463-467, 1994
    • (1994) Br J Cancer , vol.69 , pp. 463-467
    • Citro, G.1    Szczylik, C.2    Ginobbi, P.3    Zupi, G.4    Calabretta, B.5
  • 87
    • 0031044157 scopus 로고    scopus 로고
    • Folic acid-polylysine carrier improves efficacy of c-myc antisense oligodeoxynucleotides on human melanoma (M14) cells
    • Ginobbi P, Geiser TA, Ombres D, Citro G: Folic acid-polylysine carrier improves efficacy of c-myc antisense oligodeoxynucleotides on human melanoma (M14) cells. Anticancer Res 17: 29-35, 1997
    • (1997) Anticancer Res , vol.17 , pp. 29-35
    • Ginobbi, P.1    Geiser, T.A.2    Ombres, D.3    Citro, G.4
  • 88
    • 0028924955 scopus 로고
    • Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
    • Wang S, Lee RJ, Cauchon G, Gorenstein DG, Low PS: Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. Proc Natl Acad Sci USA 92: 3318-3322, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3318-3322
    • Wang, S.1    Lee, R.J.2    Cauchon, G.3    Gorenstein, D.G.4    Low, P.S.5
  • 89
    • 0031442693 scopus 로고    scopus 로고
    • Folate and antifolate pharmacology
    • Kamen B: Folate and antifolate pharmacology. Semin Oncol 24 (Suppl 18): S18-30-S18-39, 1997
    • (1997) Semin Oncol , vol.24 , Issue.18 SUPPL.
    • Kamen, B.1
  • 90
    • 0028430957 scopus 로고
    • Folate receptor-mediated DNA delivery into tumor cells: Potosomal disruption results in enhanced gene expression
    • Gottschalk S, Cristiano RJ, Smith LC, Woo SLC: Folate receptor-mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther 1: 185-191, 1994
    • (1994) Gene Ther , vol.1 , pp. 185-191
    • Gottschalk, S.1    Cristiano, R.J.2    Smith, L.C.3    Woo, S.L.C.4
  • 91
    • 0026566559 scopus 로고
    • DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood
    • Bergsagel DJ, Finegold MJ, Butel JS, Kupsky WJ, Garcea RL: DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. N Engl J Med 326: 988-993, 1992
    • (1992) N Engl J Med , vol.326 , pp. 988-993
    • Bergsagel, D.J.1    Finegold, M.J.2    Butel, J.S.3    Kupsky, W.J.4    Garcea, R.L.5
  • 92
    • 0028971951 scopus 로고
    • Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors
    • Lednicky JA, Garcea RL, Bergsagel DJ, Butel JS: Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors. Virology 212: 710-717, 1995
    • (1995) Virology , vol.212 , pp. 710-717
    • Lednicky, J.A.1    Garcea, R.L.2    Bergsagel, D.J.3    Butel, J.S.4
  • 94
    • 0022361679 scopus 로고
    • SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice
    • Palmiter RD, Chen HY, Messing A, Brinster RL: SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature 316: 457-460, 1985
    • (1985) Nature , vol.316 , pp. 457-460
    • Palmiter, R.D.1    Chen, H.Y.2    Messing, A.3    Brinster, R.L.4
  • 95
    • 0031040856 scopus 로고    scopus 로고
    • Folate receptors as potential therapeutic targets in choroid plexus tumors of SV40 transgenic mice
    • Patrick TA, Kranz DM, van Dyke TA, Poy EJ: Folate receptors as potential therapeutic targets in choroid plexus tumors of SV40 transgenic mice. J Neuro-Oncol 32: 111-123, 1997
    • (1997) J Neuro-Oncol , vol.32 , pp. 111-123
    • Patrick, T.A.1    Kranz, D.M.2    Van Dyke, T.A.3    Poy, E.J.4
  • 96
    • 6544281694 scopus 로고    scopus 로고
    • Characterization of a folate receptor-positive cell line isolated from a SV-40-Tag induced murine brain tumor
    • abstr
    • Gruner B, Moore R, Barrera H, Weitman S: Characterization of a folate receptor-positive cell line isolated from a SV-40-Tag induced murine brain tumor. Proc Am Assoc Cancer Res 39: 430 (abstr), 1998
    • (1998) Proc Am Assoc Cancer Res , vol.39 , pp. 430
    • Gruner, B.1    Moore, R.2    Barrera, H.3    Weitman, S.4
  • 97
    • 0027952583 scopus 로고
    • Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae
    • Smart EJ, Foster DC, Ying YS, Kamen BA, Anderson RGW: Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae. J Cell Biol 124: 307-313, 1994
    • (1994) J Cell Biol , vol.124 , pp. 307-313
    • Smart, E.J.1    Foster, D.C.2    Ying, Y.S.3    Kamen, B.A.4    Anderson, R.G.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.