H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2

Cellular Immunology

Volumn 286, Issue 1-2, 2013, Pages 22-30

  Song, Xin ^a   Chen, Hui Xin ^a   Wang, Xiao Yan ^b   Deng, Xi Yun ^c   Xi, Yin Xue ^a   He, Qing ^a   Peng, Tie Li ^a   Chen, Jie ^a   Chen, Wei ^a   Wong, Benjamin Chun Yu ^d   Chen, Min Hu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

CagA; Cdx2; Claudin 2; Helicobacter pylori; Invasiveness; Signal transduction; Tight junction

Indexed keywords

CAGA PROTEIN; CLAUDIN 2; TRANSCRIPTION FACTOR CDX2;

ARTICLE; BACTERIAL STRAIN; BINDING SITE; CARCINOMA CELL; CELL DEDIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; DNA FLANKING REGION; GAP JUNCTION; GENE TARGETING; GENETIC CODE; GENETIC TRANSCRIPTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; STOMACH CARCINOMA; TIGHT JUNCTION; TUMOR INVASION; UPREGULATION; WILD TYPE;

AJC; APICAL JUNCTIONAL COMPLEX; CAGA; CDX2; CLAUDIN-2; CYTOTOXIN-ASSOCIATED GENE A; DESMOSOME; DS; EDTA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMSA; ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT; FCS; FETAL CALF SERUM; HELICOBACTER PYLORI; HEPATOCYTE NUCLEAR FACTOR; HNF; IBD; INFLAMMATORY BOWEL DISEASE; INVASIVENESS; PI; PROPIDIUM IODIDE; SIGNAL TRANSDUCTION; TIGHT JUNCTION; TJ; TJ ZONE; TJZ; ZO-1; ZONULAE OCCLUDENTES-1;

ADENOCARCINOMA; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BINDING SITES; CELL DEDIFFERENTIATION; CELL LINE, TUMOR; CLAUDIN-2; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HELICOBACTER PYLORI; HOMEODOMAIN PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; NEOPLASM INVASIVENESS; PROTEIN BINDING; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TIGHT JUNCTIONS;

EID: 84888353476     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2013.10.008     Document Type: Article

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