Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype

Cancer Immunology, Immunotherapy

Volumn 62, Issue 11, 2013, Pages 1697-1709

  Göthert, Joachim Rudolf ^a   Eisele, Lewin ^a   Klein Hitpass, Ludger ^a   Weber, Stefanie ^a   Zesewitz, Marie Louise ^a   Sellmann, Ludger ^a   Röth, Alexander ^a   Pircher, Hanspeter ^b   Dührsen, Ulrich ^a   Dürig, Jan ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

CD8+ T cells; Chronic lymphocytic leukemia; Gene set enrichment analysis; KLRG1

Indexed keywords

CD38 ANTIGEN; KILLER CELL LECTIN LIKE RECEPTOR G1; NATURAL KILLER CELL LECTIN LIKE RECEPTOR; UNCLASSIFIED DRUG; UVOMORULIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL EXPANSION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; EFFECTOR CELL; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; LYMPHOCYTE FUNCTION; MAJOR CLINICAL STUDY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TUMOR MICROENVIRONMENT;

ANIMALS; CADHERINS; CD8-POSITIVE T-LYMPHOCYTES; CELL MEMBRANE; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; LECTINS, C-TYPE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MICE; MICE, INBRED C3H; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTE SUBSETS; TRANS-ACTIVATORS; TRANSCRIPTOME;

EID: 84888346574     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-013-1473-z     Document Type: Article

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