Oligoclonal TCRBV gene usage in B-cell chronic lymphocytic leukemia: Major perturbations are preferentially seen within the CD4 T-cell subset

Blood

Volumn 94, Issue 3, 1999, Pages 1063-1069

  Rezvany, Mohammad Reza ^a   Jeddi Tehrani, Mahmood ^b   Österborg, Anders ^b   Kimby, Eva ^b   Wigzell, Hans ^b   Mellstedt, Häkan ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; AGED; ANTIGEN RECOGNITION; ARTICLE; B CELL LEUKEMIA; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CODON USAGE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENETIC POLYMORPHISM; HELPER CELL; HUMAN; LEUKEMOGENESIS; LYMPHOCYTE CLONE; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE RECEPTOR GENE; T LYMPHOCYTE SUBPOPULATION;

EID: 0033178658     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.3.1063.415a17_1063_1069     Document Type: Article

References (33)

1. Fu SM, Winchester RJ, Kunkel HG: Similar idiotype specificity for the membrane IgD and IgM of human B lymphocytes. J Immunol 114:250, 1975
2. Pernis B, Brouet JC, Seligmann M: IgD and IgM on the membrane of lymphoid cells in macroglobulinemia: Evidence for identity of membrane IgD and IgM antibody activity in a case with IgG receptors. Eur J Immunol 4:776, 1974
3. Chiorazzi N, Fu SM, Moutazen G: T cell helper defect in patients with chronic lymphocytic leukemia. J Immunol 122:1087, 1979
4. Kay NE: Abnormal T cell subpopulation function in chronic lymphocytic leukemia: Excessive suppressor (T) and deficient helper (T) activity with respect to B cell proliferation. Blood 57:418, 1981
5. Lauria F, Foa F, Mantovani B: T cell functional abnormality in B-chronic lymphocytic leukemia: Evidence of a defect of the T helper subset. Br J Haematol 54:277, 1983
6. Dighiero GP, Travade P, Chevret S, Fenaux P, Chastang C, Binet JL: B cell chronic lymphocytic leukemia: Present status and future directions. Blood 78:1901, 1991
7. Foon KA, Rai KR, Gale RP: Chronic lymphocytic leukemia: New insights into biology and therapy. Ann Intern Med 113:525, 1990
8. Davis MM, Bjorkman PJ: T-cell antigen receptors genes and T-cell recognition. Nature 334:395, 1988
9. Jorgensen LJ, Reay AP, Ehrich WE, Davis MM: Molecular components of T cell recognition. Annu Rev Immunol 10:835, 1992
10. Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA: An αß T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274:209, 1996
11. Pannetier C, Cochet M, Darche S, Casrouge A, Zöller M, Kourilsky P: The sizes of the CDR3 hypervariable regions of the murine T-cell receptor ß chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci USA 90:4319, 1993
12. + T cell expansions in normal individuals and patients with rheumatoid arthritis. J Immunol 154:3538, 1995
13. Grunewald J, Tehrani MJ, Andersson R, DerSimonian H, Wigzell H: A persistent monoclonal T cell expansion in the peripheral blood of a normal adult male: A new clinical entity? Clin Exp Immunol 89:279, 1992
14. + subset in normal human subjects. J Immunol 151:5762, 1993
15. + T cell clones in elderly humans. J Immunol 158:4493, 1997
16. Farace F, Orlanducci F, Dietrich PY, Gaudin C, Angevin E, Courtier MH, Bayle C, Hercend T, Triebel F: T cell repertoire in patients with B chronic lymphocytic leukemia. Evidence for multiple in vivo T cell clonal expansions. J Immunol 153:4281, 1994
17. + T cell subsets in chronic lymphocytic leukemia. J Immunol 158:1482, 1997
18. Ideström K, Kimby E, Björkholm M, Mellstedt H, Engstedt L, Gahrton G, Johansson B, Killander D, Robérts KH, Stalfelt AM, Udén AM, Wadman B, Wählby S: Treatment of chronic lymphocytic leukaemia and well-differentiated lymphocytic lymphoma with continuous low-or intermittent high-dose prenimustine versus chlorambucil/prenisolone. Eur J Cancer Clin Oncol 18:1117, 1982
19. Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN, Pastermack BS: Clinical staging of chronic lymphocytic leukemia. Blood 46:219, 1975
20. Silver RT, Sawitsky A, Rai K, Holland JF, Glidewell O: Guidelines for protocol studies in chronic lymphocytic leukemia. Am J Hematol 4:343, 1978
21. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
22. Choi Y, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J: Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci USA 86:8941, 1989
23. Doherty JP, Roifman MC, Sueihua P, Cymerman U, Ho WKS, Thompson E, Kamel-Reid S, Cohen A: Expression of the human T cell receptor Vβ repertoire. Mol Immunol 28:607, 1991
24. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning. A Laboratory Manual (ed 2). Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
25. Cochet M, Pannetier C, Regnault A, Darche S, Leclerc C, Kourilsky P: Molecular detection and in vivo analysis of the specific T cell response to a protein antigen. Eur J Immunol 22:2639, 1992
26. + T cell expansions are found preferentially in patients with a low tumor burden. Eur J Immunol 27:2245, 1997
27. Posnett DN, Sinha R, Kabak S, Russo C: Clonal populations of T cells in normal elderly humans: The T cell equivalent to "benign monoclonal gammopathy." J Exp Med 179:609, 1994
28. Wen T, Mellstedt H, Jondal M: Presence of clonal T cell populations in chronic B lymphocytic leukemia and smoldering myeloma. J Exp Med 171:659, 1990
29. + peripheral T cells. Hum Immunol 40:93, 1994
30. Callahan JE, Kappler JW, Marrack P: Unexpected expansions of CD8-bearing cells in old mice. J Immunol 151:6657, 1993
31. Sensi M, Parmiani G: Analysis of TCR usage in human tumors: A new tool for assessing tumor-specific immune responses. Immunol Today 16:588, 1995
32. Boon T, Gajewski TF, Coulie PG: From defined human tumor antigens to defective immunization? Immunol Today 16:334, 1995
33. Salvi S, Segalla F, Rao S, Arienti F, Sartori M, Bratina G, Caronni E, Anichini A, Clemente C, Parmiani G: Overexpression of the T-cell receptor beta-chain variable region TCRBV14 in HLA-A2-matched primary human melanomas. Cancer Res 55:3374, 1995