NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy

Kidney International

Volumn 84, Issue 5, 2013, Pages 895-901

  Knauf, Felix ^a   Asplin, John R ^b   Granja, Ignacio ^b   Schmidt, Insa M ^a   Moeckel, Gilbert W ^a   David, Rachel J ^a   Flavell, Richard A ^a   Aronson, Peter S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LithoLink Corporation   (United States)

Author keywords

crystal nephropathy; inflammasome; NALP3; oxalate

Indexed keywords

CALCIUM CARBONATE; CALCIUM OXALATE; CREATININE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MESSENGER RNA; NITROGEN; OXALIC ACID; SOLUBLE OXALATE; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HISTOLOGY; HOMEOSTASIS; INFLAMMATION; KIDNEY DISEASE; KIDNEY FAILURE; MORTALITY; MOUSE; NONHUMAN; OXALIC ACID NEPHROPATHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL; WILD TYPE;

ANIMALS; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GENOTYPE; INFLAMMASOMES; INFLAMMATION MEDIATORS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEPHRITIS; OXALATES; PHENOTYPE; RENAL INSUFFICIENCY; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84888332141     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.207     Document Type: Article

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