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Volumn 24, Issue 6, 2013, Pages 480-486

Reconstituted HDL for the acute treatment of acute coronary syndrome

Author keywords

acute coronary syndrome; apoA I; cholesterol; high density lipoprotein; reverse cholesterol transport

Indexed keywords

APOLIPOPROTEIN A1; CER 001; CHOLESTEROL; CSL 111; CSL 112; ETC 216; HIGH DENSITY LIPOPROTEIN; HYPOCHOLESTEROLEMIC AGENT; MDCO 216; PLACEBO; RECONSTITUTED HIGH DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84888302969     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0000000000000020     Document Type: Review
Times cited : (66)

References (93)
  • 1
    • 23244462620 scopus 로고    scopus 로고
    • Lipoprotein retention: And clues for atheroma regression
    • Williams KJ, Tabas I. Lipoprotein retention: And clues for atheroma regression. Arterioscler Thromb Vasc Biol 2005; 25:1536-1540.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1536-1540
    • Williams, K.J.1    Tabas, I.2
  • 2
    • 56549109283 scopus 로고    scopus 로고
    • Increased inflammatory gene expression in ABC transporter-deficient macrophages: Free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions
    • Yvan-Charvet L, Welch C, Pagler TA, et al. Increased inflammatory gene expression in ABC transporter-deficient macrophages: Free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation 2008; 118:1837-1847.
    • (2008) Circulation , vol.118 , pp. 1837-1847
    • Yvan-Charvet, L.1    Welch, C.2    Pagler, T.A.3
  • 3
    • 0027253887 scopus 로고
    • Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content
    • Davies MJ, Richardson PD, Woolf N, et al. Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content. Br Heart J 1993; 69:377-381.
    • (1993) Br Heart J , vol.69 , pp. 377-381
    • Davies, M.J.1    Richardson, P.D.2    Woolf, N.3
  • 4
    • 0030857552 scopus 로고    scopus 로고
    • Relation of plaque lipid composition and morphology to the stability of human aortic plaques
    • Felton CV, Crook D, Davies MJ, Oliver MF. Relation of plaque lipid composition and morphology to the stability of human aortic plaques. Arterioscler Thromb Vasc Biol 1997; 17:1337-1345.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1337-1345
    • Felton, C.V.1    Crook, D.2    Davies, M.J.3    Oliver, M.F.4
  • 5
    • 0037072453 scopus 로고    scopus 로고
    • Multiple atherosclerotic plaque rupture in acute coronary syndrome: A three-vessel intravascular ultrasound study
    • Rioufol G, Finet G, Ginon I, et al. Multiple atherosclerotic plaque rupture in acute coronary syndrome: A three-vessel intravascular ultrasound study. Circulation 2002; 106:804-808.
    • (2002) Circulation , vol.106 , pp. 804-808
    • Rioufol, G.1    Finet, G.2    Ginon, I.3
  • 6
    • 84863337523 scopus 로고    scopus 로고
    • Characteristics and clinical significance of angiographically mild lesions in acute coronary syndromes
    • Large study of ACS patients showing radiographic features of nonculprits lesions that are associated with future events
    • Brener SJ, Mintz GS, Cristea E, et al. Characteristics and clinical significance of angiographically mild lesions in acute coronary syndromes. JACC Cardiovasc Imaging 2012; 5:S86-S94. Large study of ACS patients showing radiographic features of nonculprits lesions that are associated with future events
    • (2012) JACC Cardiovasc Imaging , vol.5
    • Brener, S.J.1    Mintz, G.S.2    Cristea, E.3
  • 7
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009; 361:1045-1057.
    • (2009) N Engl J Med , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 8
    • 84871579696 scopus 로고    scopus 로고
    • Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention: 2012 update
    • An excellent review and summary of latest treatment guidelines for ACS patients
    • Dobesh PP, Beavers CJ, Herring HR, et al. Key articles and guidelines in the management of acute coronary syndrome and in percutaneous coronary intervention: 2012 update. Pharmacotherapy 2012; 32:E348-e386. An excellent review and summary of latest treatment guidelines for ACS patients
    • (2012) Pharmacotherapy , vol.32
    • Dobesh, P.P.1    Beavers, C.J.2    Herring, H.R.3
  • 9
    • 21544467275 scopus 로고    scopus 로고
    • Pathophysiology of coronary artery disease
    • Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation 2005; 111:3481-3488.
    • (2005) Circulation , vol.111 , pp. 3481-3488
    • Libby, P.1    Theroux, P.2
  • 10
    • 0142152237 scopus 로고    scopus 로고
    • Is There A 'treatment gap' in acute coronary syndromes?
    • Krause BR, Newton RS. Is there a 'treatment gap' in acute coronary syndromes? Curr Opin Investig Drugs 2003; 4:1046-1047.
    • (2003) Curr Opin Investig Drugs , vol.4 , pp. 1046-1047
    • Krause, B.R.1    Newton, R.S.2
  • 11
    • 36448975243 scopus 로고    scopus 로고
    • High-density lipoprotein mimetics: Focus on synthetic high-density lipoprotein
    • Shah PK. High-density lipoprotein mimetics: Focus on synthetic high-density lipoprotein. Am J Cardiol 2007; 100:S62-67.
    • (2007) Am J Cardiol , vol.100
    • Shah, P.K.1
  • 12
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, et al. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization. Circulation 2001; 103:926-933.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3
  • 13
    • 33646173813 scopus 로고    scopus 로고
    • Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: A metaanalysis of randomized controlled trials
    • Briel M, Schwartz GG, Thompson PL, et al. Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: A metaanalysis of randomized controlled trials. JAMA 2006; 295:2046-2056.
    • (2006) JAMA , vol.295 , pp. 2046-2056
    • Briel, M.1    Schwartz, G.G.2    Thompson, P.L.3
  • 14
    • 84858982029 scopus 로고    scopus 로고
    • Regulation of reverse cholesterol transport: A comprehensive appraisal of available animal studies
    • An excellent review on steps in the RCT pathway
    • Annema W, Tietge UJ. Regulation of reverse cholesterol transport: A comprehensive appraisal of available animal studies. Nutr Metabol 2012; 9:25. An excellent review on steps in the RCT pathway
    • (2012) Nutr Metabol , vol.9 , pp. 25
    • Annema, W.1    Tietge, U.J.2
  • 15
    • 84859760161 scopus 로고    scopus 로고
    • Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport
    • Summary of expert consensus panel on nomenclature and challenges in developing therapeutics and diagnostics based on the RCT pathway
    • Rosenson RS, Brewer HB Jr, Davidson WS, et al. Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport. Circulation 2012; 125:1905-1919. Summary of expert consensus panel on nomenclature and challenges in developing therapeutics and diagnostics based on the RCT pathway
    • (2012) Circulation , pp. 125
    • Rosenson, R.S.1    Brewer Jr., H.B.2    Davidson, W.S.3
  • 16
    • 31044446308 scopus 로고    scopus 로고
    • Antiatherogenic role of high-density lipoproteins: Insights from genetically engineered-mice
    • Escola-Gil JC, Palomer X, Ribas V, et al. Antiatherogenic role of high-density lipoproteins: Insights from genetically engineered-mice. Front Biosci 2006; 11:1328-1348.
    • (2006) Front Biosci , vol.11 , pp. 1328-1348
    • Escola-Gil, J.C.1    Palomer, X.2    Ribas, V.3
  • 17
    • 0014963381 scopus 로고
    • Reassembly in vitro of a serum high-density lipoprotein
    • Hirz R, Scanu AM. Reassembly in vitro of a serum high-density lipoprotein. Biochim Biophys Acta 1970; 207:364-367.
    • (1970) Biochim Biophys Acta , vol.207 , pp. 364-367
    • Hirz, R.1    Scanu, A.M.2
  • 18
    • 0015212060 scopus 로고
    • Electron microscopic study on reassembly of plasma high density apoprotein with various lipids
    • Forte TM, Nichols AV, Gong EL, et al. Electron microscopic study on reassembly of plasma high density apoprotein with various lipids. Biochim Biophys Acta 1971; 248:381-386.
    • (1971) Biochim Biophys Acta , vol.248 , pp. 381-386
    • Forte, T.M.1    Nichols, A.V.2    Gong, E.L.3
  • 19
    • 0017196366 scopus 로고
    • Interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl lecithin.1. The structure of the complexes
    • Atkinson D, Smith HM, Dickson J, Austin JP. Interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl lecithin. 1. The structure of the complexes. Eur J Biochem 1976; 64:541-547.
    • (1976) Eur J Biochem , vol.64 , pp. 541-547
    • Atkinson, D.1    Smith, H.M.2    Dickson, J.3    Austin, J.P.4
  • 20
    • 0016144451 scopus 로고
    • Regulation of cellular sterol flux and synthesis by human serum lipoproteins
    • Bates SR, Rothblat GH. Regulation of cellular sterol flux and synthesis by human serum lipoproteins. Biochim Biophys Acta 1974; 360:38-55.
    • (1974) Biochim Biophys Acta , vol.360 , pp. 38-55
    • Bates, S.R.1    Rothblat, G.H.2
  • 21
    • 0016710471 scopus 로고
    • A comparative study on the removal of cellular lipids from Landschu? Tz ascites cells by human plasma apolipoproteins
    • Jackson RL, Gotto AM, Stein O, Stein Y. A comparative study on the removal of cellular lipids from Landschu? tz ascites cells by human plasma apolipoproteins. J Biol Chem 1975; 250:7204-7209.
    • (1975) J Biol Chem , vol.250 , pp. 7204-7209
    • Jackson, R.L.1    Gotto, A.M.2    Stein, O.3    Stein, Y.4
  • 22
    • 0015698504 scopus 로고
    • The removal of cholesterol from LandschH8tz ascites cells by high-density apolipoprotein
    • Stein O, Stein Y. The removal of cholesterol from LandschH8tz ascites cells by high-density apolipoprotein. Biochim Biophys Acta 1973; 326:232-244.
    • (1973) Biochim Biophys Acta , vol.326 , pp. 232-244
    • Stein, O.1    Stein, Y.2
  • 23
    • 0021733831 scopus 로고
    • Artificial HDL as an antiatherosclerotic drug
    • Orekhov AN, Misharin A, Tertov VV, et al. Artificial HDL as an antiatherosclerotic drug. Lancet 1984; 2:1149-1150.
    • (1984) Lancet , vol.2 , pp. 1149-1150
    • Orekhov, A.N.1    Misharin, A.2    Tertov, V.V.3
  • 24
    • 0024166549 scopus 로고
    • Behavior of human apolipoprotein A-I: Qhospholipid and apoHDL - Phospholipid complexes in vitro and after injection into rabbits
    • Koizumi J, Kano M, Okabayashi K, et al. Behavior of human apolipoprotein A-I: Qhospholipid and apoHDL - phospholipid complexes in vitro and after injection into rabbits. J Lipid Res 1988; 29:1405-1415.
    • (1988) J Lipid Res , vol.29 , pp. 1405-1415
    • Koizumi, J.1    Kano, M.2    Okabayashi, K.3
  • 25
    • 0024550898 scopus 로고
    • High density lipoprotein plasma fractions inhibit aortic fatty streaks in cholesterol-fed rabbits
    • Badimon JJ, Badimon L, Galvez A, et al. High density lipoprotein plasma fractions inhibit aortic fatty streaks in cholesterol-fed rabbits. Lab Invest 1989; 60:455-461.
    • (1989) Lab Invest , vol.60 , pp. 455-461
    • Badimon, J.J.1    Badimon, L.2    Galvez, A.3
  • 26
    • 0025322265 scopus 로고
    • Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit
    • Badimon JJ, Badimon L, Fuster V. Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit. J Clin Invest 1990; 85:1234-1241.
    • (1990) J Clin Invest , vol.85 , pp. 1234-1241
    • Badimon, J.J.1    Badimon, L.2    Fuster, V.3
  • 27
    • 0024592586 scopus 로고
    • A purification method for apolipoprotein A-I and A-II
    • Peitsch MC, Kress A, Lerch PG, et al. A purification method for apolipoprotein A-I and A-II. Anal Biochem 1989; 178:301-305.
    • (1989) Anal Biochem , vol.178 , pp. 301-305
    • Peitsch, M.C.1    Kress, A.2    Lerch, P.G.3
  • 28
    • 0029801069 scopus 로고    scopus 로고
    • Production and characterization of a reconstituted high density lipoprotein for therapeutic applications
    • Lerch PG, Förtsch V, Hodler G, Bolli R. Production and characterization of a reconstituted high density lipoprotein for therapeutic applications. Vox Sang 1996; 71:155-164.
    • (1996) Vox Sang , vol.71 , pp. 155-164
    • Lerch, P.G.1    Förtsch, V.2    Hodler, G.3    Bolli, R.4
  • 29
    • 0020490580 scopus 로고
    • Reaction of human lecithin cholesterol acyltransferase with synthetic micellar complexes of apolipoprotein A-I, phosphatidylcholine, and cholesterol
    • Matz CE, Jonas A. Reaction of human lecithin cholesterol acyltransferase with synthetic micellar complexes of apolipoprotein A-I, phosphatidylcholine, and cholesterol. J Biol Chem 1982; 257:4541-4546.
    • (1982) J Biol Chem , vol.257 , pp. 4541-4546
    • Matz, C.E.1    Jonas, A.2
  • 30
    • 0028835727 scopus 로고
    • Therapeutic trial of reconstituted human high-density lipoprotein in a canine model of gram-negative septic shock
    • Quezado ZM, Natanson C, Banks SM, et al. Therapeutic trial of reconstituted human high-density lipoprotein in a canine model of gram-negative septic shock. J Pharmacol Exp Ther 1995; 272:604-611.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 604-611
    • Quezado, Z.M.1    Natanson, C.2    Banks, S.M.3
  • 31
    • 0030005684 scopus 로고    scopus 로고
    • Pharmacokinetics of reconstituted human high-density lipoprotein in pigs after hemorrhagic shock with resuscitation
    • DiPiro JT, Cue JI, Richards CS, et al. Pharmacokinetics of reconstituted human high-density lipoprotein in pigs after hemorrhagic shock with resuscitation. Crit Care Med 1996; 24:440-444.
    • (1996) Crit Care Med , vol.24 , pp. 440-444
    • DiPiro, J.T.1    Cue, J.I.2    Richards, C.S.3
  • 32
    • 0027212621 scopus 로고
    • A reconstituted, apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits
    • Hubsch AP, Powell FS, Lerch PG, Doran JE. A reconstituted, apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits. Circ Shock 1993; 40:14-23.
    • (1993) Circ Shock , vol.40 , pp. 14-23
    • Hubsch, A.P.1    Powell, F.S.2    Lerch, P.G.3    Doran, J.E.4
  • 33
    • 0028853618 scopus 로고
    • Reconstituted high-density lipoprotein reduces LPS-stimulated TNF alpha
    • Casas AT, Hubsch AP, Rogers BC, Doran JE. Reconstituted high-density lipoprotein reduces LPS-stimulated TNF alpha. J Surg Res 1995; 59:544-552.
    • (1995) J Surg Res , vol.59 , pp. 544-552
    • Casas, A.T.1    Hubsch, A.P.2    Rogers, B.C.3    Doran, J.E.4
  • 34
    • 0028842055 scopus 로고
    • Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood
    • Parker TS, Levine DM, Chang JC, et al. Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood. Infect Immun 1995; 63:253-258.
    • (1995) Infect Immun , vol.63 , pp. 253-258
    • Parker, T.S.1    Levine, D.M.2    Chang, J.C.3
  • 35
    • 0029829525 scopus 로고    scopus 로고
    • Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia
    • Pajkrt D, Doran JE, Koster F, et al. Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia. J Exp Med 1996; 184: 1601-1608.
    • (1996) J Exp Med , vol.184 , pp. 1601-1608
    • Pajkrt, D.1    Doran, J.E.2    Koster, F.3
  • 36
    • 0028865357 scopus 로고
    • High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules
    • Cockerill GW, Rye KA, Gamble JR, et al. High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. Arterioscler Thromb Vasc Biol 1995; 15:1987-1994.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1987-1994
    • Cockerill, G.W.1    Rye, K.A.2    Gamble, J.R.3
  • 37
    • 0030869430 scopus 로고    scopus 로고
    • Complexes of apoA-1 with phosphatidylcholine suppress dysregulation of arterial tone by oxidized LDL
    • Ota Y, Kugiyama K, Sugiyama S, et al. Complexes of apoA-1 with phosphatidylcholine suppress dysregulation of arterial tone by oxidized LDL. Am J Physiol 1997; 273:H1215-1222.
    • (1997) Am J Physiol , vol.273
    • Ota, Y.1    Kugiyama, K.2    Sugiyama, S.3
  • 38
    • 0031826009 scopus 로고    scopus 로고
    • Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo
    • Lerch PG, Spycher MO, Doran JE. Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo. Thromb Haemost 1998; 80:316-320.
    • (1998) Thromb Haemost , vol.80 , pp. 316-320
    • Lerch, P.G.1    Spycher, M.O.2    Doran, J.E.3
  • 39
    • 0032921161 scopus 로고    scopus 로고
    • Acute effects of intravenous infusion of ApoA1/phosphatidylcholine discs on plasma lipoproteins in humans
    • Nanjee MN, Doran JE, Lerch PG, Miller NE. Acute effects of intravenous infusion of ApoA1/phosphatidylcholine discs on plasma lipoproteins in humans. Arterioscler Thromb Vasc Biol 1999; 19:979-989.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 979-989
    • Nanjee, M.N.1    Doran, J.E.2    Lerch, P.G.3    Miller, N.E.4
  • 40
    • 0033543084 scopus 로고    scopus 로고
    • Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans
    • Eriksson M, Carlson LA, Miettinen TA, Angelin B. Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans. Circulation 1999; 100:594-598.
    • (1999) Circulation , vol.100 , pp. 594-598
    • Eriksson, M.1    Carlson, L.A.2    Miettinen, T.A.3    Angelin, B.4
  • 41
    • 10744221774 scopus 로고    scopus 로고
    • Effects of intravenous apolipoprotein A-I/ phosphatidylcholine discs on LCAT PLTP, and CETP in plasma and peripheral lymph in humans
    • Kujiraoka T, Nanjee MN, Oka T, et al. Effects of intravenous apolipoprotein A-I/ phosphatidylcholine discs on LCAT, PLTP, and CETP in plasma and peripheral lymph in humans. Arterioscler Thromb Vasc Biol 2003; 23:1653-1659.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1653-1659
    • Kujiraoka, T.1    Nanjee, M.N.2    Oka, T.3
  • 42
    • 0037177140 scopus 로고    scopus 로고
    • High-density lipoprotein restores endothelial function in hypercholesterolemic men
    • Spieker LE, Sudano I, Hurlimann D, et al. High-density lipoprotein restores endothelial function in hypercholesterolemic men. Circulation 2002; 105: 1399-1402.
    • (2002) Circulation , vol.105 , pp. 1399-1402
    • Spieker, L.E.1    Sudano, I.2    Hurlimann, D.3
  • 43
    • 0038311032 scopus 로고    scopus 로고
    • Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein
    • Bisoendial RJ, Hovingh GK, Levels JHM, et al. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein. Circulation 2003; 107:2944-2948.
    • (2003) Circulation , vol.107 , pp. 2944-2948
    • Bisoendial, R.J.1    Hovingh, G.K.2    Levels, J.H.M.3
  • 44
    • 1842863230 scopus 로고    scopus 로고
    • Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/ endothelial nitric oxide synthase
    • Viswambharan H, Ming X-F, Zhu S, et al. Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/ endothelial nitric oxide synthase. Circ Res 2004; 94:918-925.
    • (2004) Circ Res , vol.94 , pp. 918-925
    • Viswambharan, H.1    Ming, X.-F.2    Zhu, S.3
  • 45
    • 34247397359 scopus 로고    scopus 로고
    • Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial
    • Tardif JC, L'Allier PL, Ibrahim R, et al. Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial. JAMA 2007; 297:1675-1682.
    • (2007) JAMA , vol.297 , pp. 1675-1682
    • Tardif, J.C.1    L'Allier, P.L.2    Ibrahim, R.3
  • 46
    • 34547631773 scopus 로고    scopus 로고
    • Reconstituted HDL increases circulating endothelial progenitor cells in patients with type 2 diabetes
    • van Oostrom O, Nieuwdorp M, Westerweel PE, et al. Reconstituted HDL increases circulating endothelial progenitor cells in patients with type 2 diabetes. Arterioscler Thromb Vasc Biol 2007; 27:1864-1865.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1864-1865
    • Van Oostrom, O.1    Nieuwdorp, M.2    Westerweel, P.E.3
  • 47
    • 58149153296 scopus 로고    scopus 로고
    • Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque
    • Shaw JA, Bobik A, Murphy A, et al. Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque. Circ Res 2008; 103:1084-1091.
    • (2008) Circ Res , vol.103 , pp. 1084-1091
    • Shaw, J.A.1    Bobik, A.2    Murphy, A.3
  • 48
    • 84865116393 scopus 로고    scopus 로고
    • Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice
    • Interesting study on the effect of CSL-111 on HDL metabolism and the RCT pathway in mice. Results show both similarities and differences between results found in human studies, thus raising caution in the use of animal models for assessing rHDL therapies
    • Chen Z, O'Neill EA, Meurer RD, et al. Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice. J Cardiovasc Pharmacol Ther 2012; 17:315-323. Interesting study on the effect of CSL-111 on HDL metabolism and the RCT pathway in mice. Results show both similarities and differences between results found in human studies, thus raising caution in the use of animal models for assessing rHDL therapies
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , pp. 315-323
    • Chen, Z.1    O'Neill, E.A.2    Meurer, R.D.3
  • 50
    • 84883633431 scopus 로고    scopus 로고
    • CSL112, a novel formulation of human apoA-IO, rapidly activates lecithin-cholesterol acyltransferase upon infusion into rabbits and monkeys
    • Easton R, Diditchenko S, Spycher M, et al. CSL112, a novel formulation of human apoA-IO, rapidly activates lecithin-cholesterol acyltransferase upon infusion into rabbits and monkeys. Coll Cardiol 2012; 59:E492.
    • (2012) Coll Cardiol , vol.59
    • Easton, R.1    Diditchenko, S.2    Spycher, M.3
  • 51
    • 84888306641 scopus 로고    scopus 로고
    • CSL a novel formulation of dramatically increases cholesterol efflux capacity in healthy subjects
    • abstract]
    • Gille A, Easton R, Wright SD, et al. CSL a novel formulation of dramatically increases cholesterol efflux capacity in healthy subjects. Circulation 2012 [abstract]; 112.
    • (2012) Circulation , vol.112
    • Gille, A.1    Easton, R.2    Wright, S.D.3
  • 52
    • 79955880471 scopus 로고    scopus 로고
    • Lecithin cholesterol acyltransferase: An anti or pro-atherogenic factor?
    • Rousset X, Shamburek R, Vaisman B, et al. Lecithin cholesterol acyltransferase: An anti or pro-atherogenic factor? Curr Atheroscler Rep 2011; 13:249-256.
    • (2011) Curr Atheroscler Rep , vol.13 , pp. 249-256
    • Rousset, X.1    Shamburek, R.2    Vaisman, B.3
  • 53
    • 0019226420 scopus 로고
    • A-imilano apoprotein decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an italian family
    • Franceschini G, Sirtori CR, Capurso A, et al. A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest 1980; 66:892-900.
    • (1980) J Clin Invest , vol.66 , pp. 892-900
    • Franceschini, G.1    Sirtori, C.R.2    Capurso, A.3
  • 54
    • 33645090443 scopus 로고    scopus 로고
    • Recombinant apolipoprotein A-IMilano for the treatment of cardiovascular diseases
    • Calabresi L, Sirtori CR, Paoletti R, Franceschini G. Recombinant apolipoprotein A-IMilano for the treatment of cardiovascular diseases. Curr Atheroscler Rep 2006; 8:163-167.
    • (2006) Curr Atheroscler Rep , vol.8 , pp. 163-167
    • Calabresi, L.1    Sirtori, C.R.2    Paoletti, R.3    Franceschini, G.4
  • 55
    • 0020644932 scopus 로고
    • Apolipoprotein A-IMilano. Detection of normal A-I in affected subjects and evidence for a cysteine for arginine substitution in the variant A-I
    • Weisgraber KH, Rall SC, Bersot TP, et al. Apolipoprotein A-IMilano. Detection of normal A-I in affected subjects and evidence for a cysteine for arginine substitution in the variant A-I. J Biol Chemistry 1983; 258:2508-2513.
    • (1983) J Biol Chemistry , vol.258 , pp. 2508-2513
    • Weisgraber, K.H.1    Rall, S.C.2    Bersot, T.P.3
  • 56
    • 0033977770 scopus 로고    scopus 로고
    • Metabolism of apolipoproteins AI and AII in subjects carrying similar apoAI mutations, apoAI Milano and apoAI Paris
    • Perez-Mendez O, Bruckert E, Franceschini G, et al. Metabolism of apolipoproteins AI and AII in subjects carrying similar apoAI mutations, apoAI Milano and apoAI Paris. Atherosclerosis 2000; 148:317-325.
    • (2000) Atherosclerosis , vol.148 , pp. 317-325
    • Perez-Mendez, O.1    Bruckert, E.2    Franceschini, G.3
  • 57
    • 0025193688 scopus 로고
    • Apolipoprotein AIMilano. Disulfide-linked dimers increase high density lipoprotein stability and hinder particle interconversion in carrier plasma
    • Franceschini G CL, Tosi C, Gianfranceschi G, et al. Apolipoprotein AIMilano. Disulfide-linked dimers increase high density lipoprotein stability and hinder particle interconversion in carrier plasma. J Biol Chem 1990; 265:1224-1231.
    • (1990) J Biol Chem , vol.265 , pp. 1224-1231
    • Franceschini G, C.L.1    Tosi, C.2    Gianfranceschi, G.3
  • 58
    • 77953891139 scopus 로고    scopus 로고
    • Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles
    • Bhat S, Sorci-Thomas MG, Calabresi L, et al. Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles. Biochemistry 2010; 49:5213-5224.
    • (2010) Biochemistry , vol.49 , pp. 5213-5224
    • Bhat, S.1    Sorci-Thomas, M.G.2    Calabresi, L.3
  • 59
    • 0030691945 scopus 로고    scopus 로고
    • High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice
    • Bielicki JK, Forte TM, McCall MR, et al. High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice. J Lipid Res 1997; 38:2314-2321.
    • (1997) J Lipid Res , vol.38 , pp. 2314-2321
    • Bielicki, J.K.1    Forte, T.M.2    McCall, M.R.3
  • 60
    • 0032890429 scopus 로고    scopus 로고
    • Recombinant apolipoproteins for the treatment of vascular diseases
    • Sirtori CR, Calabresi L, Franceschini G. Recombinant apolipoproteins for the treatment of vascular diseases. Atherosclerosis 1999; 142:29-40.
    • (1999) Atherosclerosis , vol.142 , pp. 29-40
    • Sirtori, C.R.1    Calabresi, L.2    Franceschini, G.3
  • 61
    • 0036231933 scopus 로고    scopus 로고
    • Use of recombinant apolipoproteins in vascular diseases: The case of apoA-I
    • Chiesa G, Sirtori CR. Use of recombinant apolipoproteins in vascular diseases: The case of apoA-I. Curr Opin Investig Drugs 2002; 3:420-426.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 420-426
    • Chiesa, G.1    Sirtori, C.R.2
  • 62
    • 0033534183 scopus 로고    scopus 로고
    • Cell cholesterol efflux to reconstituted high-density lipoproteins containing the apolipoprotein A-IMilano dimer
    • Calabresi L, Canavesi M, Bernini F, Franceschini G. Cell cholesterol efflux to reconstituted high-density lipoproteins containing the apolipoprotein A-IMilano dimer. Biochemistry 1999; 38:16307-16314.
    • (1999) Biochemistry , vol.38 , pp. 16307-16314
    • Calabresi, L.1    Canavesi, M.2    Bernini, F.3    Franceschini, G.4
  • 63
    • 34247171332 scopus 로고    scopus 로고
    • A unique protease-sensitive high density lipoprotein particle containing the apolipoprotein A-I(Milano) dimer effectively promotes ATP-binding Cassette A1-mediated cell cholesterol efflux
    • Favari E, Gomaraschi M, Zanotti I, et al. A unique protease-sensitive high density lipoprotein particle containing the apolipoprotein A-I(Milano) dimer effectively promotes ATP-binding Cassette A1-mediated cell cholesterol efflux. J Biol Chem 2007; 282:5125-5132.
    • (2007) J Biol Chem , vol.282 , pp. 5125-5132
    • Favari, E.1    Gomaraschi, M.2    Zanotti, I.3
  • 64
    • 0035957282 scopus 로고    scopus 로고
    • Cholesterol mobilization by free and lipidbound apoAI(Milano) and apoAI(Milano)-apoAII heterodimers
    • Wang WQ, Moses AS, Francis GA. Cholesterol mobilization by free and lipidbound apoAI(Milano) and apoAI(Milano)-apoAII heterodimers. Biochemistry 2001; 40:3666-3673.
    • (2001) Biochemistry , vol.40 , pp. 3666-3673
    • Wang, W.Q.1    Moses, A.S.2    Francis, G.A.3
  • 65
    • 70349579203 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano
    • Alexander ET, Weibel GL, Joshi MR, et al. Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano. Arterioscler Thromb Vasc Biol 2009; 29:1496-1501.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1496-1501
    • Alexander, E.T.1    Weibel, G.L.2    Joshi, M.R.3
  • 66
    • 84865743356 scopus 로고    scopus 로고
    • Reduced biliary sterol output with no change in total fecal excretion in mice expressing a human apolipoprotein A-I variant
    • Parolini C, Caligari S, Gilio D, et al. Reduced biliary sterol output with no change in total fecal excretion in mice expressing a human apolipoprotein A-I variant. Liver Int 2012; 32:1363-1371.
    • (2012) Liver Int , vol.32 , pp. 1363-1371
    • Parolini, C.1    Caligari, S.2    Gilio, D.3
  • 67
    • 0027172984 scopus 로고
    • In vivo metabolism of a mutant form of apolipoprotein A-I, apo A-IMilano, associated with familial hypoalphalipoproteinemia
    • Roma P, Gregg RE, Meng MS, et al. In vivo metabolism of a mutant form of apolipoprotein A-I, apo A-IMilano, associated with familial hypoalphalipoproteinemia. J Clin Invest 1993; 91:1445-1452.
    • (1993) J Clin Invest , vol.91 , pp. 1445-1452
    • Roma, P.1    Gregg, R.E.2    Meng, M.S.3
  • 68
    • 0027994776 scopus 로고
    • Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits
    • Ameli S, Hultgardh-Nilsson A, Cercek B, et al. Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits. Circulation 1994; 90:1935-1941.
    • (1994) Circulation , vol.90 , pp. 1935-1941
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Cercek, B.3
  • 69
    • 0038012797 scopus 로고    scopus 로고
    • Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries
    • Kaul S, Rukshin V, Santos R, et al. Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries. Circulation 2003; 107:2551-2554.
    • (2003) Circulation , vol.107 , pp. 2551-2554
    • Kaul, S.1    Rukshin, V.2    Santos, R.3
  • 70
    • 4444249250 scopus 로고    scopus 로고
    • Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)- phospholipid complex
    • Kaul S, Coin B, Hedayiti A, et al. Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)-phospholipid complex. J Am Coll Cardiol 2004; 44:1311-1319.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1311-1319
    • Kaul, S.1    Coin, B.2    Hedayiti, A.3
  • 71
    • 0242577955 scopus 로고    scopus 로고
    • Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial
    • Nissen SE, Tsunoda T, Tuzcu EM, et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial. JAMA 2003; 290:2292-2300.
    • (2003) JAMA , vol.290 , pp. 2292-2300
    • Nissen, S.E.1    Tsunoda, T.2    Tuzcu, E.M.3
  • 72
    • 40649126377 scopus 로고    scopus 로고
    • Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: In vivo assessment by intravascular ultrasound and magnetic resonance imaging
    • Parolini C, Marchesi M, Lorenzon P, et al. Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: In vivo assessment by intravascular ultrasound and magnetic resonance imaging. J Am Coll Cardiol 2008; 51:1098-1103.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1098-1103
    • Parolini, C.1    Marchesi, M.2    Lorenzon, P.3
  • 73
    • 84155166795 scopus 로고    scopus 로고
    • Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type
    • A mouse study directly comparing ApoA-I milano versus wild-type apoA-1 on atherosclerosis, which showed overall similarities in the two proteins but some advantages to ApoA-I milano in reducing markers of inflammation
    • Ibanez B, Giannarelli C, Cimmino G, et al. Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type). Atherosclerosis 2012; 220:72-77. A mouse study directly comparing ApoA-I milano versus wild-type apoA-1 on atherosclerosis, which showed overall similarities in the two proteins but some advantages to ApoA-I milano in reducing markers of inflammation
    • (2012) Atherosclerosis , vol.220 , pp. 72-77
    • Ibanez, B.1    Giannarelli, C.2    Cimmino, G.3
  • 74
    • 40649089928 scopus 로고    scopus 로고
    • Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: Magnetic resonance imaging study in an experimental model of atherosclerosis
    • Ibanez B VG, Cimmino G, Speidl WS, et al. Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: Magnetic resonance imaging study in an experimental model of atherosclerosis. J Am Coll Cardiol 2008; 51:1104-1109.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1104-1109
    • Ibanez B, V.G.1    Cimmino, G.2    Speidl, W.S.3
  • 75
    • 66149181903 scopus 로고    scopus 로고
    • Separation of product associating E. Coli host cell proteins oppA and dppa from recombinant apolipoprotein A in an industrial HIC unit operation
    • Hunter AK, Wang X, Suda EJ, et al. Separation of product associating E. coli host cell proteins OppA and DppA from recombinant apolipoprotein A in an industrial HIC unit operation. Biotechnol Prog 2008; 25:446-453; 25.
    • (2008) Biotechnol Prog , vol.2544
    • Hunter, A.K.1    Wang, X.2    Suda, E.J.3
  • 76
    • 81055140563 scopus 로고    scopus 로고
    • Progress in HDL-based therapies for atherosclerosis
    • Chyu K-Y, Peter A, Shah PK. Progress in HDL-based therapies for atherosclerosis. Curr Atheroscler Rep 2011; 13:405-412.
    • (2011) Curr Atheroscler Rep , vol.13 , pp. 405-412
    • Chyu, K.-Y.1    Peter, A.2    Shah, P.K.3
  • 77
    • 74849134637 scopus 로고    scopus 로고
    • Integrated solution to purification challenges in the manufacture of a soluble recombinant protein in E. Coli
    • Caparon MH, Rust KJ, Hunter AK, et al. Integrated solution to purification challenges in the manufacture of a soluble recombinant protein in E. coli. Biotechnol Bioeng 2010; 105:239-249.
    • (2010) Biotechnol Bioeng , vol.105 , pp. 239-249
    • Caparon, M.H.1    Rust, K.J.2    Hunter, A.K.3
  • 78
    • 84888301808 scopus 로고    scopus 로고
    • MDCO-216 (Apo A-I Milano/ POPC complex) administered to cynomolgus monkeys induces pronounced changes in plasma lipids and apolipoproteins
    • Kempen HJ BS, Zerler B, Plassmann S, et al. MDCO-216 (Apo A-I Milano/ POPC complex) administered to cynomolgus monkeys induces pronounced changes in plasma lipids and apolipoproteins. Circulation 2011; 124:A10978.
    • (2011) Circulation , vol.124
    • Kempen H.J, B.S.1    Zerler, B.2    Plassmann, S.3
  • 79
    • 0031827934 scopus 로고    scopus 로고
    • Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein AI (Milano
    • Chiesa G, Stoltzfus LJ, Michelagnoli S, et al. Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein AI (Milano). Atherosclerosis 1998; 136:139-146.
    • (1998) Atherosclerosis , vol.136 , pp. 139-146
    • Chiesa, G.1    Stoltzfus, L.J.2    Michelagnoli, S.3
  • 80
    • 0031827934 scopus 로고    scopus 로고
    • Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein AIMilano
    • Chiesa G SL, Michelagnoli S, Bielicki JK, et al. Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein AIMilano. Atherosclerosis 1998; 136:139-146.
    • (1998) Atherosclerosis , vol.136 , pp. 139-146
    • Chiesa G, S.L.1    Michelagnoli, S.2    Bielicki, J.K.3
  • 81
    • 0035954267 scopus 로고    scopus 로고
    • High-dose recombinant apolipoprotein AI (milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice.Potential implications for acute plaque stabilization
    • Shah PK, Yano J, Reyes O, et al. High-dose recombinant apolipoprotein AI (milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilization. Circulation 2001; 103:3047-3050.
    • (2001) Circulation , vol.103 , pp. 3047-3050
    • Shah, P.K.1    Yano, J.2    Reyes, O.3
  • 83
    • 84888293638 scopus 로고    scopus 로고
    • Charged lipoprotein complexes and their uses
    • Patent Application Publication US 0217312 A1 September 2006
    • Dasseux JL. Charged lipoprotein complexes and their uses. United States Patent Application Publication US 0217312 A1 September 2006; 28.
    • United States , vol.28
    • Dasseux, J.L.1
  • 84
    • 0020662151 scopus 로고
    • Reconstitution of apolipoprotein A-I from human high density lipoprotein with bovine brain sphingomyelin
    • Swaney JB. Reconstitution of apolipoprotein A-I from human high density lipoprotein with bovine brain sphingomyelin. J Biol Chem 1983; 258:1254-1259.
    • (1983) J Biol Chem , vol.258 , pp. 1254-1259
    • Swaney, J.B.1
  • 85
    • 0027169391 scopus 로고
    • Role of sphingomyelin in the regulation of cholesterol esterification in the plasma lipoproteins. Inhibition of lecithin-cholesterol acyltransferase reaction
    • Subbaiah PV, Liu M. Role of sphingomyelin in the regulation of cholesterol esterification in the plasma lipoproteins. Inhibition of lecithin-cholesterol acyltransferase reaction. J Biol Chem 1993; 268:20156-20163.
    • (1993) J Biol Chem , vol.268 , pp. 20156-20163
    • Subbaiah, P.V.1    Liu, M.2
  • 86
    • 0029782733 scopus 로고    scopus 로고
    • Sphingomyelin inhibits the lecithin-cholesterol acyltransferase reaction with reconstituted high density lipoproteins by decreasing enzyme binding
    • Bolin DJ, Jonas A. Sphingomyelin inhibits the lecithin-cholesterol acyltransferase reaction with reconstituted high density lipoproteins by decreasing enzyme binding. J Biol Chem 1996; 271:19152-19158.
    • (1996) J Biol Chem , vol.271 , pp. 19152-19158
    • Bolin, D.J.1    Jonas, A.2
  • 87
    • 0030039634 scopus 로고    scopus 로고
    • The influence of sphingomyelin on the structure and function of reconstituted high density lipoproteins
    • Rye KA, Hime NJ, Barter PJ. The influence of sphingomyelin on the structure and function of reconstituted high density lipoproteins. J Biol Chem 1996; 271:4243-4250.
    • (1996) J Biol Chem , vol.271 , pp. 4243-4250
    • Rye, K.A.1    Hime, N.J.2    Barter, P.J.3
  • 88
    • 84879432847 scopus 로고    scopus 로고
    • CER-001, a synthetic HDL-mimetic, safely mobilizes cholesterol in healthy dyslipidemic volunteers
    • Keyserling CH, Hunt TL, Klepp HM, et al. CER-001, a synthetic HDL-mimetic, safely mobilizes cholesterol in healthy dyslipidemic volunteers. Circulation 2011; 124:; A15525.
    • (2011) Circulation , vol.124
    • Keyserling, C.H.1    Hunt, T.L.2    Klepp, H.M.3
  • 89
    • 0031907135 scopus 로고    scopus 로고
    • Effects of sphingomyelin and cholesterol on lipoprotein lipase-mediated lipolysis in lipid emulsions
    • Arimoto I, Saito H, Kawashima Y, et al. Effects of sphingomyelin and cholesterol on lipoprotein lipase-mediated lipolysis in lipid emulsions. J Lipid Res 1998; 39:143-151.
    • (1998) J Lipid Res , vol.39 , pp. 143-151
    • Arimoto, I.1    Saito, H.2    Kawashima, Y.3
  • 90
    • 77957222802 scopus 로고    scopus 로고
    • Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice
    • Rousset X, Vaisman B, Auerbach B, et al. Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice. J Pharmacol Exp Ther 2010; 335:140-148.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 140-148
    • Rousset, X.1    Vaisman, B.2    Auerbach, B.3
  • 91
    • 84869991362 scopus 로고    scopus 로고
    • Measurement of reverse cholesterol transport pathways in humans: In vivo rates of free cholesterol efflux, esterification, and excretion
    • First report of a novel method based on the use of stable isotopes of cholesterol for assessing the RCT pathway in human individuals. Method shows potential promise for monitoring the effect of new HDL-modulating drugs on the RCT pathway
    • Turner S, Voogt J, Davidson M, et al. Measurement of reverse cholesterol transport pathways in humans: In vivo rates of free cholesterol efflux, esterification, and excretion. J Am Heart Association 2012; 1:E001826. First report of a novel method based on the use of stable isotopes of cholesterol for assessing the RCT pathway in human individuals. Method shows potential promise for monitoring the effect of new HDL-modulating drugs on the RCT pathway
    • (2012) J Am Heart Association
    • Turner, S.1    Voogt, J.2    Davidson, M.3
  • 92
    • 33947307937 scopus 로고    scopus 로고
    • Apolipoprotein AI mimetic peptides: Qossible new agents for the treatment of atherosclerosis
    • Sethi AA, Amar M, Shamburek RD, Remaley AT. Apolipoprotein AI mimetic peptides: Qossible new agents for the treatment of atherosclerosis. Curr Opin Investig Drugs 2007; 8:201-212.
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 201-212
    • Sethi, A.A.1    Amar, M.2    Shamburek, R.D.3    Remaley, A.T.4
  • 93
    • 77955173940 scopus 로고    scopus 로고
    • Structure/function relationships of apolipoprotein a-I mimetic peptides: Implications for antiatherogenic activities of high-density lipoprotein
    • D'Souza W, Stonik JA, Murphy A, et al. Structure/function relationships of apolipoprotein a-I mimetic peptides: Implications for antiatherogenic activities of high-density lipoprotein. Circ Res 2010; 107:217-227.
    • (2010) Circ Res , vol.107 , pp. 217-227
    • D'Souza, W.1    Stonik, J.A.2    Murphy, A.3


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