Production and characterization of a reconstituted high density lipoprotein for therapeutic applications

Vox Sanguinis

Volumn 71, Issue 3, 1996, Pages 155-164

  Lerch, Peter G ^a   Förtsch, Vreni ^a   Hodler, Gerhard ^a   Bolli, Reinhard ^a  

^a Central Laboratory in Bern   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; CHOLIC ACID; HIGH DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE;

ARTICLE; ATHEROSCLEROSIS; DIALYSIS; ELECTRON MICROSCOPY; FREEZE DRYING; PASTEURIZATION; PLASMA; PRIORITY JOURNAL; SEPTIC SHOCK; VIRUS INACTIVATION;

EID: 0029801069     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.1996.7130155.x     Document Type: Article

References (62)

1. Miller GJ, Miller NE: Plasma-high-density-lipoprotein concentration and development of ischaemic heart disease. Lancet 1975;i:16-19.
2. Glomset JA: The plasma lecithin:cholesterol acyltransferase reaction. J Lipid Res 1968;9: 155-167.
3. Fielding CJ, Shore VG, Fielding PE: A protein cofactor of lecithin:cholesterol acyltransferase. Biochem Biophys Res Commun 1972;46: 1493-1498.
4. Ulevitch RJ, Johnston AR, Weinstein DB: New function for high density lipoproteins: Their participation in intravascular reactions of bacterial lipopolysaccharides. J Clin Invest 1979;64: 1516-1524.
5. Freudenberg MA, Bog-Hansen TC, Back U, Galanos C: Interaction of lipopolysaccharides with plasma high-density lipoprotein in rat. Infect Immun 1980;28:373-380.
6. Munford RS, Hall CL, Dietschy JM: Binding of Salmonella typhimurium lipopolysaccharides to rat high-density lipoproteins. Infect Immun 1981;34:835-843.
7. Levine DM, Parker TS, Donnelly TM, Walsh A, Rubin AL: In vivo protection against endotoxin by plasma high density lipoprotein. Proc Natl Acad Sci USA 1993;90:12040-12044.
8. Hubsch AP, Powell FS, Lerch PG, Doran JE: A reconstituted, apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits. Circ Shock 1993;40:14-23.
9. Hubsch AP, Casas AT, Doran JE: Protective effects of reconstituted high density lipoproteins in rabbit gram negative bacteremia models. J Lab Clin Med 1995;126:548-558.
10. James RW, Hochstrasser AC, Borghini I, Martin B, Pometta D, Hochstrasser D: Characterization of a human high density lipoprotein-associated protein, NA1/NA2 - identity with SP-40,40, an inhibitor of complement-mediated cytolysis. Arterioscler Thromb 1991;11:645-652.
11. Broze GJ, Warren LA, Novotny WF, Higuchi DA, Girard JJ, Miletich JP: The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: Insight into its possible mechanism of action. Blood 1988;71:335-343.
12. Benditt EP, Eriksen N: Amyloid protein SAA is associated with high density lipoprotein from human serum. Proc Natl Acad Sci USA 1977; 74:4025-4028.
13. de Beer FC, Soutar AK, Baltz ML, Trayner IM, Feinstein A, Pepy MB: Low density lipoprotein and very low density lipoprotein are selectively bound by aggregated C-reactive protein. J Exp Med 1982;156:230-242.
14. Ho YK, Brown MS, Goldstein JL: Hydrolysis and excretion of cytoplasmic cholesteryl esters by macrophages: Stimulation by high density lipoproteins and other agents. J Lipid Res 1980; 21:391-398.
15. Brook JG, Aviram M: Platelet lipoprotein interactions. Semin Thromb Hemost 1988;14:258-265.
16. Owens RJ, Anantharamaiah GM, Kahlon JB, Srinivas RV, Compans RW, Segrest JP: Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formation. J Clin Invest 1990;86:1142-1150.
17. Hajduk SL, Moore DR, Vasudevacharaya J, Siqueira H, Torri AF, Tytler EM, Esko JD: Lysis of Trypanosoma brucei by toxic subspecies of human high density lipoprotein. J Biol Chem 1989;264:5210-5217.
18. Boyles JK, Zoellner CD, Anderson LJ, Kosik LM, Pitas RE, Weisgraber KH, Hui DJ, Mahley RW, Gebickehaerter PJ, Ignatius MJ, Shooter EM: A role for apolipoprotein-E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J Clin Invest 1989;83:1015-1031.
19. Peitsch MC, Kress A, Lerch PG, Morgenthaler JJ, Isliker H, Heiniger HJ: A purification method for apolipoprotein A-I and A-II. Anal Biochem 1989;178:301-305.
20. Lerch PG, Morgenthaler JJ, Peitsch MC, Friedli H, Hodler G, Doran JE, Isliker H, Heiniger HJ: Isolation and properties of apolipoprotein A for therapeutic use. Protides Biol Fluids 1989;36: 409-416.
21. Nanjee MN, Crouse JR, King JM, Hovorka R, Rees SE, Carson ER, Morgenthaler JJ, Lerch P, Miller NE: Effects of intravenous infusion of lipid-free apolipoprotein A-I in humans. Arterioscler Thromb, in press.
22. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
23. Hara I, Okazaki M: High-performance liquid chromatography of scrum lipoproteins. Methods Enzymol 1986;129:57-78.
24. Markwell MAK, Haas SM, Bieber LL, Tolbert NE: A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 1978; 87:206-210.
25. Gornall AG, Bardawill CJ, David MM: Determination of serum proteins by means of the Biuret reaction. J Biol Chem 1949;177:751-766.
26. Swaney JB, O'Brien K: Cross-linking studies of the self-association properties of apoA-I and apoA-II from human high density lipoprotein. J Biol Chem 1978;253:7069-7077.
27. Chen PS, Toribara TY, Warner H: Microdetermination of phosphorus. Anal Chem 1956;28: 1756-1758.
28. Forte TM, Nordhausen RW: Electron microscopy of negatively stained lipoproteins. Methods Enzymol 1986;128:442-457.
29. Chen Y-H, Yang JT, Martinez HM: Determination of secondary structures of proteins by circular dichroism and optical rotatory dispersion. Biochemistry 1972;11:4120-4131.
30. Chen GC, Kane JP: Circular dichroism of lipoprotein lipids. Methods Enzymol 1986;128: 519-527.
31. Chen CH, Albers JJ: Interspecies activation of lecithin-cholesterol acyltransferase by apolipoprotein A-I isolated from the plasma of humans, horses, sheep, goats and rabbits. Biochim Biophys Acta 1983;753:40-46.
32. Albers JJ, Adolphson JL, Chen CH: Radioimmunoassay of human plasma lecithin-cholesterol acyltransferase. J Clin Invest 1981;67:141-148.
33. Bonelli FS, Jonas A: Reaction of lecithin cholesterol acyltransferase with water-soluble substrates. J Biol Chem 1989;264:14723-14728.
34. Wurfel MM, Kunitake ST, Lichenstein H, Kane JP, Wright SD: Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med 1994;180:1025-1035.
35. Kistler P, Nitschmann H: Large scale production of human plasma fractions. Vox Sang 1962; 7:414-424.
36. Lux SE, Hirz R, Shrager RI, Gotto AM: The influence of lipid on the conformation of human plasma high density apolipoproteins. J Biol Chem 1972;247:2598-2606.
37. Assmann G, Brewer HB: Lipid-protein interactions in high density lipoproteins. Proc Natl Acad Sci USA 1974;71:989-993.
38. Wald JH, Krul ES, Jonas A: Structure of apolipoprotein-A-I in three homogeneous, reconstituted high density lipoprotein particles. J Biol Chem 1990;265:20037-20043.
39. Sparks DL, Lund-Katz S, Phillips MC: The charge and structural stability of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. J Biol Chem 1992; 267:25839-25847.
40. Jonas A: Lecithin-cholesterol acyltransferase in the metabolism of high-density lipoproteins. Biochim Biophys Acta 1991;1084:205-220.
41. Schumaker VN, Puppione DL: Sequential flotation ultracentrifugation. Methods Enzymol 1986;128:155-170.
42. Brewer HB, Ronan R, Meng M, Bishop C: Isolation and characterization of apolipoproteins A-I, A-II, and A-IV Methods Enzymol 1986; 128:223-246.
43. Hamilton RL, Williams MC, Fielding CJ, Havel RJ: Discoidal structure of nascent high density lipoproteins from perfused rat liver. J Clin Invest 1976;58:667-680.
44. Hénin Y, Maréchal V, Barré-Sinoussi F, Chermann J-C, Morgenthaler JJ: Inactivation and partition of human immunodeficiency virus during Kistler and Nitschmann fractionation of human blood plasma. Vox Sang 1988;54:78-83.
45. Kobayashi H, Tsuzuki M: The effect of disinfectants and heat on hepatitis B virus. J Hosp Infect 1984;5(suppl A):93-94.
46. Gerety RJ, Aronson DL: Plasma derivatives and viral hepatitis. Transfusion 1982;22:347-351.
47. Cuthbertson B, Rennie JG, Aw D: Safety of albumin preparations manufactured from plasma not tested for HIV antibody. Lancet 1987;ii:41.
48. Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R: Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc Natl Acad Sci USA 1993;90:2793-2797.
49. Prince AM, Horowitz B, Brotman B: Sterilization of hepatitis and HTLV-II viruses by exposure to tri(n-butyl)phosphate and sodium cholate. Lancet 1986;i:706.
50. Billigton D, Coleman R: Effects of bile salts on human erythrocytes. Plasma membrane vesiculation, phospholipid solubilization and their possible relationship to bile secretion. Biochim Biophys Acta 1978;509:33-47.
51. Shiao YJ, Chen JC, Wang CN, Wang TC: The mode of action of primary bile salts on human platelets. Biochim Biophys Acta 1993;1146: 282-293.
52. Bonomo EA, Swaney JB: A rapid method for the synthesis of protein-lipid complexes using adsorption chromatography. J Lipid Res 1988; 29:380-384.
53. Jonas A: Reconstitution of high-density lipoproteins. Methods Enzymol 1986;128:553-582.
54. Brouillette CG, Anantharamaia GM: Structural models of human apolipoprotein A-I. Biochim Biophys Acta 1995;1256:103-129.
55. Atkinson D, Small DM: Recombinant lipoproteins: Implications for structure and assembly of native lipoproteins. Annu Rev Biophys Chem 1986;15:403-456.
56. Doran JE, Lerch P, Hubsch AP: Natural and artificial lipoproteins modulate lipopolysaccharide-induced tumor necrosis factor production in vitro and in vivo. Old Herborn University Semin 1994;5:106-121.
57. Cué JI, DiPiro JT, Brunner LJ, Doran JE, Blankenship ME, Mansberger AR, Hawkins ML: Reconstituted high density lipoprotein inhibits physiologic and tumor necrosis factor response to lipopolysaccharide in rabbits. Arch Surg 1994;129:193-197.
58. Nichols AV, Gong EL, Blanche PJ, Forte TM: Characterization of discoidal complexes of phosphatidylcholine, apolipoprotein A-I and cholesterol by gradient gel electrophoresis. Biochim Biophys Acta 1983;750:353-364.
59. Sparks DL, Davidson WS, Lund-Katz S, Phillips MC: Effect of cholesterol on the charge and structure of apolipoprotein A-I recombinant high density lipoprotein particles. J Biol Chem 1993;268:23250-23257.
60. Hubsch AP, Doran JE, Lerch PG, Hodler G, Morgenthaler JJ, Heiniger HJ: Apolipoprotein A-I-enriched lipoprotein attenuates tumor necrosis factor production and shock in an anesthetized rabbit endotoxemia model; in Faist E (ed): Host Defense Dysfunction in Trauma, Shock and Sepsis. Heidelberg, Springer, 1993, pp 789-793.
61. Quezado ZMN, Natanson C, Banks SM, Alling DW, Koey CA, Danner RL, Elin RJ, Hosseini JM, Parker TS, Levine DM, Rubin AL, Hoffman WD: Therapeutic trial of reconstituted human high-density lipoprotein in a canine model of gram-negative septic shock. J Pharmacol Exp Ther 1995;272:604-611.
62. Casas AT, Hubsch AP, Carter BC, Doran JE: Reconstituted high-density lipoprotein reduces LPS-stimulated TNFα. J Surg Res 1995;59: 544-552.