Complexes of apoA-1 with phosphatidylcholine suppress dysregulation of arterial tone by oxidized LDL

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 3 42-3, 1997, Pages

  Ota, Yasutaka ^a   Kugiyama, Kiyotaka ^a   Sugiyama, Seigo ^a   Matsumura, Toshiyuki ^a   Terano, Tsuyoshi ^b   Yasue, Hirofumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b Chemo Sero Therapeutic Research Institute   (Japan)

Author keywords

Endothelium; High density lipoproteins; Lysophosphatidylcholine; Spontaneous lipid transfer

Indexed keywords

APOLIPOPROTEIN A1; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HIGH DENSITY LIPOPROTEIN; LYSOPHOSPHATIDYLCHOLINE; OXIDIZED LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTERY TONE; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ISOLATED ARTERY; LIPID PEROXIDATION; LIPID TRANSPORT; NONHUMAN; PRIORITY JOURNAL; SWINE; VASOMOTOR REFLEX;

EID: 0030869430     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.3.h1215     Document Type: Article

References (13)

1. Bossaller, C., G. B. Habib, H. Yamamoto, C. Williams, S. Wells, and P. D. Henry. Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5′-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J. Clin. Invest. 79: 170-174, 1987.
2. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal. Biochem. 72: 248-254, 1976.
3. Doody, M. C., H. J. Pownall, Y. J. Kao, and L. C. Smith. Mechanism and kinetics of transfer of a fluorescent fatty acid between single-walled phosphatidylcholine vesicles. Biochemistry 19: 108-116, 1980.
4. Galle, J., E. Bassenge, and R. Busse. Oxidized low density lipoproteins potentiate vasoconstrictions to various agonists by direct interaction with vascular smooth muscle. Circ. Res. 66: 1287-1293, 1990.
5. Gerner, E. W., A. E. Crus, D. G. Stickney, D. K. Holmes, and P. S. Culver. Factors regulating membrane permeability alter thermal resistance. Ann. NY Acad. Sci. 335: 215-233, 1980.
6. Green, D. H. R., A. R. Tall, and R. M. Glickman. Rat intestine secretes discoid high density lipoprotein. J. Clin. Invest. 61: 528-534, 1978.
7. Hara, H., and S. Yokoyama. Interaction of free apolipoprotein with macrophages. J. Biol. Chem. 266: 3080-3086, 1991.
8. Jamieson, D. G., D. C. Usher, D. J. Rader, and E. Lavi. Apolipoprotein (a) deposition in atherosclerotic plaques of cerebral vessels. A potential role for endothelial cells in lesion formation. Am. J. Pathol. 147: 1567-1574, 1995.
9. Jonas, A. Reconstitution of high-density lipoproteins. Methods Enzymol. 128: 553-582, 1986.
10. Jones, L. A., T. Teramoto, D. J. Juhn, R. B. Goldberg, A. H. Rubenstein, and G. S. Getz. Characterization of lipoprotein produced by the perfused rhesus monkey liver. J. Lipid. Res. 25: 319-335, 1984.
11. Kugiyama, K., S. A. Kerns, J. D. Morrisett, R. Roberts, and P. D. Henry. Impairment of endothelium-dependent arterial relaxation by lysolecitin in modified low-density lipoproteins. Nature 344: 160-162, 1990.
12. Kugiyama, K., M. Ohgushi, S. Sugiyama, T. Murohara, K. Fukunaga, E. Miyamoto, and H. Yasue. Lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation. Circ. Res. 71: 1422-1428, 1992.
13. Kugiyama, K., T. Sakamoto, I. Misumi, S. Sugiyama, M. Ohgushi, H. Ogawa, M. Horiguchi, and H. Yasue. Transferable lipids in oxidized low-density lipoprotein stimulate plasminogen activator inhibitor-1 and inhibit tissue-type plasminogen activator release from endothelial cells. Circ. Res. 73: 335-343, 1993.