Characterization of a pituitary-tumor-derived cell line, TtT/GF, that expresses Hoechst efflux ABC transporter subfamily G2 and stem cell antigen 1

Cell and Tissue Research

Volumn 354, Issue 2, 2013, Pages 563-572

  Mitsuishi, Hideo ^a   Kato, Takako ^a   Chen, Mo ^a   Cai, Li Yi ^a,b   Yako, Hideji ^a   Higuchi, Masashi ^a   Yoshida, Saishu ^a   Kanno, Naoko ^a   Ueharu, Hiroki ^a   Kato, Yukio ^a  

^a MEIJI UNIVERSITY   (Japan)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

ABC transporter; Hoechst 33342; Sca1; Stem cell; TtT GF cell line

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; STEM CELL ANTIGEN 1;

ABCB1A GENE; ABCB1B GENE; ABCG2 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; GENE; GENE EXPRESSION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SCA1 GENE; TTT GF CELL LINE;

ANIMALS; ANTIGENS, LY; ANTIGENS, SURFACE; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; MALE; MEMBRANE PROTEINS; MICE; PITUITARY GLAND; PITUITARY NEOPLASMS; RATS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84888295437     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-013-1686-7     Document Type: Article

References (53)

1. Alarid ET, Windle JJ, Whyte DB, Mellon PL (1996) Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice. Development 122:3319-3329
2. Allaerts W, Vankelecom H (2005) History and perspectives of pituitary folliculo-stellate cell research. Eur J Endocrinol 153:1-12
3. Batts TD, Machado HL, Zhang Y, Creighton CJ, Li Y, Rosen JM (2011) Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One 6:e27841
4. Bunting KD (2002) ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells 20:11-20
5. Cai LY, Kato T, Chen M, Wang H, Sekine E-I, Izumi SI, Kato Y (2012) Accumulated HSV1-TK proteins interfere with spermatogenesis through a disruption of integrity of Sertoli-germ cell junctions. J Reprod Dev 58:544-551
6. Chapman L, Nishimura A, Buckingham JC, Morris JF, Christian HC (2002) Externalization of annexin I from a folliculo-stellate-like cell line. Endocrinology 143:4330-4338
7. Chen J, Gremeaux L, Fu Q, Liekens D, Van Laere S, Vankelecom H (2009) Pituitary progenitor cells tracked down by side population dissection. Stem Cells 27:1182-1195
8. Chen L, Maruyama D, Sugiyama M, Sakai T, Mogi C, Kato M, Kurotani R, Shirasawa N, Takaki A, Renner U, Kato Y, Inoue K (2000) Cytological characterization of a pituitary folliculo-stellate-like cell line, Tpit/F1, with special reference to adenosine triphosphate-mediated neural nitric oxide synthetase expression and nitric oxide secretion. Endocrinology 141:3603-3310
9. Devnath S, Inoue K (2008) An insight to pituitary folliculo-stellate cells. J Neuroendocrinol 20:687-691
10. Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, Ross DD (1998) A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A 95:15665-15670
11. Dutsch-Wicherek M (2010) RCAS1, MT, and vimentin as potential markers of tumor microenvironment remodeling. Am J Reprod Immunol 63:181-188
12. Elkind NB, Szentpetery Z, Apati A, Ozvegy-Laczka C, Varady G, Ujhelly O, Szabo K, Homolya L, Varadi A, Buday L, Keri G, Nemet K, Sarkadi B (2005) Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Res 65:1770-1777
13. Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC (1996) Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183:1797-1806
14. Gussoni E, Soneoka Y, Strickland CD, Buzney EA, Khan MK, Flint AF, Kunkel LM, Mulligan RC (1999) Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 401:390-394
15. Herman S, Delio M, Morrow B, Samanich J (2012) Agnathia-otocephaly complex: a case report and examination of the OTX2 and PRRX1 genes. Gene 491:124-129
16. Higuchi M, Kato T, Chen M, Yako H, Yoshida S, Kanno N, Kato Y (2013) Temporospatial gene expression of Prx1 and Prx2 are involved in morphogenesis of cranial placode-derived tissues through epithelio-mesenchymal interaction during rat embryogenesis. Cell Tissue Res 353:27-40
17. Huang HC, Hu CH, Tang MC, Wang WS, Chen PM, Su Y (2007) Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. Oncogene 26:2781-2790
18. Inoue K, Matsumoto H, Koyama C, Shibata K, Nakazato Y, Ito A (1992) Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor. Endocrinology 131:3110-3116
19. Inoue K, Mogi C, Ogawa S, Tomida M, Miyai S (2002) Are folliculo-stellate cells in the anterior pituitary gland supportive cells or organ-specific stem cells? Arch Physiol Biochem 110:50-53
20. Ishikawa T, Ikegami Y, Sano K, Nakagawa H, Sawada S (2006) Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells. Curr Pharm Des 12:313-325
21. Islam MO, Kanemura Y, Tajria J, Mori H, Kobayashi S, Shofuda T, Miyake J, Hara M, Yamasaki M, Okano H (2005) Characterization of ABC transporter ABCB1 expressed in human neural stem/progenitor cells. FEBS Lett 579:3473-3480
22. Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K (2007) Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes. Endocrinology 148:1518-1523
23. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418:41-49
24. Jin L, Zhang S, Burguera BG, Couce ME, Osamura RY, Kulig E, Lloyd RV (2000) Leptin and leptin receptor expression in rat and mouse pituitary cells. Endocrinology 141:333-339
25. Korsching E, Packeisen J, Liedtke C, Hungermann D, Wulfing P, Diest PJ van, Brandt B, Boecker W, Buerger H (2005) The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol 206:451-457
26. Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelial- mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172:973-981
27. Lohrer P, Gloddek J, Hopfner U, Losa M, Uhl E, Pagotto U, Stalla GK, Renner U (2001) Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro. Neuroendocrinology 74:95-105
28. Maschler S, Gebeshuber CA, Wiedemann EM, Alacakaptan M, Schreiber M, Custic I, Beug H (2010) Annexin A1 attenuates EMT and metastatic potential in breast cancer. EMBO Mol Med 2:401-414
29. Matsson P, Pedersen JM, Norinder U, Bergstrom CA, Artursson P (2009) Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs. Pharm Res 26:1816-1831
30. Mogi C, Miyai S, Nishimura Y, Fukuro H, Yokoyama K, Takaki A, Inoue K (2004) Differentiation of skeletal muscle from pituitary folliculo-stellate cells and endocrine progenitor cells. Exp Cell Res 292:288-294
31. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
32. Osuna M, Sonobe Y, Itakura E, Devnath S, Kato T, Kato Y, Inoue K (2012) Differentiation capacity of native pituitary folliculostellate cells and brain astrocytes. J Endocrinol 213:231-237
33. Perez Castro C, Nagashima AC, Pereda MP, Goldberg V, Chervin A, Largen P, Renner U, Stalla GK, Arzt E (2000) The gp130 cytokines interleukin-11 and ciliary neurotropic factor regulate through specific receptors the function and growth of lactosomatotropic and folliculostellate pituitary cell lines. Endocrinology 141:1746-1753
34. Renner U, Gloddek J, Arzt E, Inoue K, Stalla GK (1997) Interleukin-6 is an autocrine growth factor for folliculostellate-like TtT/GF mouse pituitary tumor cells. Exp Clin Endocrinol Diabetes 105:345-352
35. Sarkadi B, Ozvegy-Laczka C, Nemet K, Varadi A (2004) ABCG2 - a transporter for all seasons. FEBS Lett 567:116-120
36. Sawicki WT, Kujawa M, Jankowska-Steifer E, Mystkowska ET, Hyc A, Kowalewski C (2006) Temporal/spatial expression and efflux activity of ABC transporter, P-glycoprotein/Abcb1 isoforms and Bcrp/Abcg2 during early murine development. Gene Expr Patterns 6:738-746
37. Spangrude GJ, Heimfeld S, Weissman IL (1988) Purification and characterization of mouse hematopoietic stem cells. Science 241:58-62
38. Strutz F, Okada H, Lo CW, Danoff T, Carone RL, Tomaszewski JE, Neilson EG (1995) Identification and characterization of a fibroblast marker: FSP1. J Cell Biol 130:393-405
39. Susa T, Kato T, Yoshida S, Yako M, Higuchi M, Kato Y (2012) Paired-related homeodomain proteins Prx1 and Prx2 are expressed in embryonic pituitary stem/progenitor cells and may be involved in the early stage of pituitary differentiation. J Neuroendocrinol 24:1201-1212
40. Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani SA (2010) Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A 107:15449-15454
41. Theile D, Staffen B, Weiss J (2010) ATP-binding cassette transporters as pitfalls in selection of transgenic cells. Anal Biochem 399:246-250
42. Traverso V, Christian HC, Morris JF, Buckingham JC (1999) Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells. Endocrinology 140:4311-4319
43. Vankelecom H (2007) Non-hormonal cell types in the pituitary candidating for stem cell. Semin Cell Dev Biol 18:559-570
44. Vankelecom H (2010) Pituitary stem/progenitor cells: embryonic players in the adult gland? Eur J Neurosci 32:2063-2081
45. Vankelecom H (2012) Pituitary stem cells drop their mask. Curr Stem Cell Res Ther 7:36-71
46. Veen HW van, Higgins CF, Konings WN (2001) Molecular basis of multidrug transport by ATP-binding cassette transporters: a proposed two-cylinder engine model. J Mol Microbiol Biotechnol 3:185-192
47. Vlotides G, Cruz-Soto M, Rubinek T, Eigler T, Auernhammer CJ, Melmed S (2006) Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells. Mol Endocrinol 20:3321-3335
48. + channels by cell contact in a cloned folliculo-stellate cell (TtT/GF). Endocrinology 138:4346-4350
49. Yoshida S, Kato T, Susa T, Cai L-Y, Nakayama M, Kato Y (2009) PROP1 coexists with SOX2 and induces PIT1-commitment cells. Biochem Biophys Res Commun 385:11-15
50. Yoshida S, Kato T, Yako H, Susa T, Cai L-Y, Osuna M, Inoue K, Kato Y (2011) Significant quantitative and qualitative transition in pituitary stem/progenitor cells occurs during the postnatal development of the rat anterior pituitary. J Neuroendocrinol 23:933-943
51. Zhang KH, Tian HY, Gao X, Lei WW, Hu Y, Wang DM, Pan XC, Yu ML, Xu GJ, Zhao FK, Song JG (2009) Ferritin heavy chain-mediated iron homeostasis and subsequent increased reactive oxygen species production are essential for epithelial-mesenchymal transition. Cancer Res 69:5340-5348
52. Zhang ZX, Koike K, Sakamoto Y, Jikihara H, Kanda Y, Inoue K, Hirota K, Miyake A (1997) Pituitary folliculo-stellate-like cell line produces a cytokine-induced neutrophil chemoattractant. Neuropeptides 31:46-51
53. Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, Sorrentino BP (2001) The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7:1028-1034