Accumulated HSV1-TK proteins interfere with spermatogenesis through a disruption of the integrity of Sertoli-germ cell junctions

Journal of Reproduction and Development

Volumn 58, Issue 5, 2012, Pages 544-551

  Cai, Li Yi ^a,b   Kato, Takako ^b   Chen, Mo ^b   Wang, HongHua ^a   Sekine, Ei ichiro ^b   Izumi, Shun ichiro ^c   Kato, Yukio ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b MEIJI UNIVERSITY   (Japan)

^c TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

HSV1 TK; Infertility; Spermatogenesis; Testin; Transgenic rat

Indexed keywords

PROTEIN; RECOMBINANT PROTEIN; TESTIN PROTEIN, RAT; THYMIDINE KINASE; VIRUS PROTEIN;

ANIMAL; ARTICLE; CELL JUNCTION; CROSS BREEDING; ENZYMOLOGY; EPIDIDYMIS; FISCHER 344 RAT; GENE EXPRESSION PROFILING; GENETICS; GENITAL HERPES; HERPES SIMPLEX VIRUS 1; HUMAN; MALE; MALE INFERTILITY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RAT; SERTOLI CELL; SPERMATOGENESIS; SPERMATOZOON; TESTIS; TRANSGENIC RAT; ULTRASTRUCTURE; VIROLOGY;

ANIMALS; CROSSES, GENETIC; EPIDIDYMIS; GENE EXPRESSION PROFILING; HERPES GENITALIS; HERPESVIRUS 1, HUMAN; HUMANS; INFERTILITY, MALE; INTERCELLULAR JUNCTIONS; MALE; PROTEINS; RATS; RATS, INBRED F344; RATS, TRANSGENIC; RECOMBINANT PROTEINS; SERTOLI CELLS; SPERMATOGENESIS; SPERMATOZOA; TESTIS; THYMIDINE KINASE; VIRAL PROTEINS;

ANIMALIA; RATTUS; SIMPLEXVIRUS;

EID: 84869036029     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.2011-010     Document Type: Article

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