The PERICLES research program: An integrated approach to characterize the combined effects of mixtures of pesticide residues to which the French population is exposed

Toxicology

Volumn 313, Issue 2-3, 2013, Pages 83-93

  Crepet A ^a   Heraud F ^a,f   Bechaux C ^a   Gouze, M E ^a   Pierlot, S ^a   Fastier, A ^a   Leblanc, J Ch ^a   Le Hegarat L ^b   Takakura, N ^b   Fessard, V ^b   Tressou, J ^c   Maximilien, R ^d   de Sousa, G ^e   Nawaz, A ^e   Zucchini Pascal, N ^e   Rahmani, R ^e   Audebert, M ^e   Graillot, V ^e   Cravedi, J P ^e  

^a FRENCH AGENCY FOR FOOD   (France)

^b ANSES (French Agency for Food   (France)

^c Food Risk Analysis Methodologies   (France)

^d INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^e TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^f EUROPEAN FOOD SAFETY AUTHORITY   (Italy)

Author keywords

Cytoxicity; Dietary exposure; Dose addition; Genotoxicity; In vitro toxicity tests; Pesticide mixtures; PXR transactivation

Indexed keywords

CAPTAN; CLOFENVINFOS; CYHALOTHRIN; CYPRODINIL; CYTOCHROME P450 3A4; DIELDRIN; DIPHENYLAMINE; ENILCONAZOLE; ETHION; FENITROTHION; IPRODIONE; LINURON; MALEIC HYDRAZIDE; METHIDATHION; PESTICIDE RESIDUE; PHOSALONE; PROCYMIDONE; TRIADIMENOL; CELL RECEPTOR; DRUG MIXTURE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL FUNCTION; CYTOTOXICITY; DIETARY EXPOSURE; DIETARY INTAKE; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; HEALTH HAZARD; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; KIDNEY CELL; LIVER CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; TOXICITY TESTING; TRANSACTIVATION; ANALYSIS; ANIMAL; BIOASSAY; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; DRUG MIXTURE; FOOD CONTAMINATION; FRANCE; GENETICS; MEDICAL RESEARCH; METHODOLOGY; PREDICTIVE VALUE; PROCEDURES; STANDARDS; TOXICITY; TRANSCRIPTION INITIATION; CYTOXICITY; DOSE ADDITION; DRUG EFFECT; IN VITRO TOXICITY TESTS; PESTICIDE MIXTURES; PXR TRANSACTIVATION; STANDARD;

RATTUS;

ANIMALS; APOPTOSIS; BIOMEDICAL RESEARCH; CELL LINE; CELL SURVIVAL; COMPLEX MIXTURES; ENDPOINT DETERMINATION; ENVIRONMENTAL EXPOSURE; FOOD CONTAMINATION; FRANCE; HUMANS; OXIDATIVE STRESS; PESTICIDE RESIDUES; PREDICTIVE VALUE OF TESTS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESEARCH DESIGN; TOXICITY TESTS; TRANSCRIPTIONAL ACTIVATION;

CYTOXICITY; DIETARY EXPOSURE; DOSE ADDITION; GENOTOXICITY; IN VITRO TOXICITY TESTS; PESTICIDE MIXTURES; PXR TRANSACTIVATION;

EID: 84888287363     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.04.005     Document Type: Article

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