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Volumn 12, Issue 1, 2013, Pages

Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

Author keywords

ARMS; ERMS; MEF2D; Myogenin and MyoD; Rhabdomyosarcoma

Indexed keywords

AGAR; LUCIFERASE; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2D PROTEIN; MYOD PROTEIN; MYOGENIN; MYOSIN HEAVY CHAIN; PROTEIN P21; UNCLASSIFIED DRUG;

EID: 84888234168     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-150     Document Type: Article
Times cited : (30)

References (51)
  • 1
    • 0033588883 scopus 로고    scopus 로고
    • Rhabdomyosarcoma-working out the pathways
    • Merlino G, Helman LJ. Rhabdomyosarcoma-working out the pathways. Oncogene 1999, 18:5340-5348.
    • (1999) Oncogene , vol.18 , pp. 5340-5348
    • Merlino, G.1    Helman, L.J.2
  • 2
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • Barr FG, Galili N, Holick J, Biegel JA, Rovera G, Emanuel BS. Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 1993, 3:113-117.
    • (1993) Nat Genet , vol.3 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 4
    • 0033997229 scopus 로고    scopus 로고
    • Skeletal muscle development in the mouse embryo
    • Kablar B, Rudnicki MA. Skeletal muscle development in the mouse embryo. Histol Histopathol 2000, 15:649-656.
    • (2000) Histol Histopathol , vol.15 , pp. 649-656
    • Kablar, B.1    Rudnicki, M.A.2
  • 5
    • 0038480134 scopus 로고    scopus 로고
    • Looking back to the embryo: defining transcriptional networks in adult myogenesis
    • Parker MH, Seale P, Rudnicki MA. Looking back to the embryo: defining transcriptional networks in adult myogenesis. Nat Rev Genet 2003, 4:497-507.
    • (2003) Nat Rev Genet , vol.4 , pp. 497-507
    • Parker, M.H.1    Seale, P.2    Rudnicki, M.A.3
  • 6
    • 0036437330 scopus 로고    scopus 로고
    • Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos
    • Pownall ME, Gustafsson MK, Emerson CP. Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. Annu Rev Cell Dev Biol 2002, 18:747-783.
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 747-783
    • Pownall, M.E.1    Gustafsson, M.K.2    Emerson, C.P.3
  • 8
    • 0027297310 scopus 로고
    • Myogenin gene disruption results in perinatal lethality because of severe muscle defect
    • Nabeshima Y, Hanaoka K, Hayasaka M, Esumi E, Li S, Nonaka I, Nabeshima Y. Myogenin gene disruption results in perinatal lethality because of severe muscle defect. Nature 1993, 364:532-535.
    • (1993) Nature , vol.364 , pp. 532-535
    • Nabeshima, Y.1    Hanaoka, K.2    Hayasaka, M.3    Esumi, E.4    Li, S.5    Nonaka, I.6    Nabeshima, Y.7
  • 9
  • 10
  • 11
    • 63049120997 scopus 로고    scopus 로고
    • MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state
    • Yang Z, MacQuarrie KL, Analau E, Tyler AE, Dilworth FJ, Cao Y, Diede SJ, Tapscott SJ. MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state. Genes Dev 2009, 23:694-707.
    • (2009) Genes Dev , vol.23 , pp. 694-707
    • Yang, Z.1    MacQuarrie, K.L.2    Analau, E.3    Tyler, A.E.4    Dilworth, F.J.5    Cao, Y.6    Diede, S.J.7    Tapscott, S.J.8
  • 12
    • 38049147787 scopus 로고    scopus 로고
    • MEF2: a central regulator of diverse developmental programs
    • Potthoff MJ, Olson EN. MEF2: a central regulator of diverse developmental programs. Development 2007, 134:4131-4140.
    • (2007) Development , vol.134 , pp. 4131-4140
    • Potthoff, M.J.1    Olson, E.N.2
  • 13
    • 0028279115 scopus 로고
    • Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis
    • Edmondson DG, Lyons GE, Martin JF, Olson EN. Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development 1994, 120:1251-1263.
    • (1994) Development , vol.120 , pp. 1251-1263
    • Edmondson, D.G.1    Lyons, G.E.2    Martin, J.F.3    Olson, E.N.4
  • 15
    • 4644220664 scopus 로고    scopus 로고
    • A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation
    • Penn BH, Bergstrom DA, Dilworth FJ, Bengal E, Tapscott SJ. A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation. Genes Dev 2004, 18:2348-2353.
    • (2004) Genes Dev , vol.18 , pp. 2348-2353
    • Penn, B.H.1    Bergstrom, D.A.2    Dilworth, F.J.3    Bengal, E.4    Tapscott, S.J.5
  • 16
    • 0029590104 scopus 로고
    • Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
    • Molkentin JD, Black BL, Martin JF, Olson EN. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell 1995, 83:1125-1136.
    • (1995) Cell , vol.83 , pp. 1125-1136
    • Molkentin, J.D.1    Black, B.L.2    Martin, J.F.3    Olson, E.N.4
  • 17
    • 0032437107 scopus 로고    scopus 로고
    • Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
    • Black BL, Olson EN. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol 1998, 14:167-196.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 167-196
    • Black, B.L.1    Olson, E.N.2
  • 18
    • 0030894683 scopus 로고    scopus 로고
    • Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
    • Han J, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 1997, 386:296-299.
    • (1997) Nature , vol.386 , pp. 296-299
    • Han, J.1    Jiang, Y.2    Li, Z.3    Kravchenko, V.V.4    Ulevitch, R.J.5
  • 19
    • 0030988939 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway
    • Dodou E, Treisman R. The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway. Mol Cell Biol 1997, 17:1848-1859.
    • (1997) Mol Cell Biol , vol.17 , pp. 1848-1859
    • Dodou, E.1    Treisman, R.2
  • 20
    • 0034698113 scopus 로고    scopus 로고
    • Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4
    • Youn HD, Grozinger CM, Liu JO. Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4. J Biol Chem 2000, 275:22563-22567.
    • (2000) J Biol Chem , vol.275 , pp. 22563-22567
    • Youn, H.D.1    Grozinger, C.M.2    Liu, J.O.3
  • 21
    • 33645655559 scopus 로고    scopus 로고
    • Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells
    • D'Andrea M, Pisaniello A, Serra C, Senni MI, Castaldi L, Molinaro M, Bouche M. Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells. J Cell Physiol 2006, 207:379-388.
    • (2006) J Cell Physiol , vol.207 , pp. 379-388
    • D'Andrea, M.1    Pisaniello, A.2    Serra, C.3    Senni, M.I.4    Castaldi, L.5    Molinaro, M.6    Bouche, M.7
  • 23
    • 0036165434 scopus 로고    scopus 로고
    • MEF2: a calcium-dependent regulator of cell division, differentiation and death
    • McKinsey TA, Zhang CL, Olson EN. MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci 2002, 27:40-47.
    • (2002) Trends Biochem Sci , vol.27 , pp. 40-47
    • McKinsey, T.A.1    Zhang, C.L.2    Olson, E.N.3
  • 24
    • 0037162697 scopus 로고    scopus 로고
    • Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
    • Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 2002, 110:479-488.
    • (2002) Cell , vol.110 , pp. 479-488
    • Zhang, C.L.1    McKinsey, T.A.2    Chang, S.3    Antos, C.L.4    Hill, J.A.5    Olson, E.N.6
  • 25
    • 0034635987 scopus 로고    scopus 로고
    • Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
    • Lu J, McKinsey TA, Nicol RL, Olson EN. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proc Natl Acad Sci U S A 2000, 97:4070-4075.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4070-4075
    • Lu, J.1    McKinsey, T.A.2    Nicol, R.L.3    Olson, E.N.4
  • 27
    • 84878849371 scopus 로고    scopus 로고
    • Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation
    • Sebastian S, Faralli H, Yao Z, Rakopoulos P, Palii C, Cao Y, Singh K, Liu QC, Chu A, Aziz A, et al. Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation. Genes Dev 2013, 27:1247-1259.
    • (2013) Genes Dev , vol.27 , pp. 1247-1259
    • Sebastian, S.1    Faralli, H.2    Yao, Z.3    Rakopoulos, P.4    Palii, C.5    Cao, Y.6    Singh, K.7    Liu, Q.C.8    Chu, A.9    Aziz, A.10
  • 30
    • 0027414452 scopus 로고
    • Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis
    • Tapscott SJ, Thayer MJ, Weintraub H. Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. Science 1993, 259:1450-1453.
    • (1993) Science , vol.259 , pp. 1450-1453
    • Tapscott, S.J.1    Thayer, M.J.2    Weintraub, H.3
  • 31
    • 33646041022 scopus 로고    scopus 로고
    • Results of a prospective minimal disseminated disease study in human rhabdomyosarcoma using three different molecular markers
    • Sartori F, Alaggio R, Zanazzo G, Garaventa A, Di Cataldo A, Carli M, Rosolen A. Results of a prospective minimal disseminated disease study in human rhabdomyosarcoma using three different molecular markers. Cancer 2006, 106:1766-1775.
    • (2006) Cancer , vol.106 , pp. 1766-1775
    • Sartori, F.1    Alaggio, R.2    Zanazzo, G.3    Garaventa, A.4    Di Cataldo, A.5    Carli, M.6    Rosolen, A.7
  • 32
    • 84873835668 scopus 로고    scopus 로고
    • Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors
    • MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ. Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors. Mol Cell Biol 2013, 33:773-784.
    • (2013) Mol Cell Biol , vol.33 , pp. 773-784
    • MacQuarrie, K.L.1    Yao, Z.2    Fong, A.P.3    Diede, S.J.4    Rudzinski, E.R.5    Hawkins, D.S.6    Tapscott, S.J.7
  • 33
    • 0026020867 scopus 로고
    • An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers
    • Sun XH, Baltimore D. An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers. Cell 1991, 64:459-470.
    • (1991) Cell , vol.64 , pp. 459-470
    • Sun, X.H.1    Baltimore, D.2
  • 34
    • 79960348707 scopus 로고    scopus 로고
    • Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes
    • Londhe P, Davie JK. Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes. Skelet Muscle 2011, 1:14.
    • (2011) Skelet Muscle , vol.1 , pp. 14
    • Londhe, P.1    Davie, J.K.2
  • 35
    • 35748951646 scopus 로고    scopus 로고
    • Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle
    • Davie JK, Cho JH, Meadows E, Flynn JM, Knapp JR, Klein WH. Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol 2007, 311:650-664.
    • (2007) Dev Biol , vol.311 , pp. 650-664
    • Davie, J.K.1    Cho, J.H.2    Meadows, E.3    Flynn, J.M.4    Knapp, J.R.5    Klein, W.H.6
  • 37
    • 32544460284 scopus 로고    scopus 로고
    • Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1
    • Ohkawa Y, Marfella CG, Imbalzano AN. Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1. Embo J 2006, 25:490-501.
    • (2006) Embo J , vol.25 , pp. 490-501
    • Ohkawa, Y.1    Marfella, C.G.2    Imbalzano, A.N.3
  • 40
    • 29244459745 scopus 로고    scopus 로고
    • P21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells
    • Ciccarelli C, Marampon F, Scoglio A, Mauro A, Giacinti C, De Cesaris P, Zani BM. p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells. Mol Cancer 2005, 4:41.
    • (2005) Mol Cancer , vol.4 , pp. 41
    • Ciccarelli, C.1    Marampon, F.2    Scoglio, A.3    Mauro, A.4    Giacinti, C.5    De Cesaris, P.6    Zani, B.M.7
  • 41
    • 77954541388 scopus 로고    scopus 로고
    • P21 downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment
    • Hecker RM, Amstutz RA, Wachtel M, Walter D, Niggli FK, Schafer BW. p21 downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment. Oncogene 2010, 29:3942-3952.
    • (2010) Oncogene , vol.29 , pp. 3942-3952
    • Hecker, R.M.1    Amstutz, R.A.2    Wachtel, M.3    Walter, D.4    Niggli, F.K.5    Schafer, B.W.6
  • 42
    • 84859569795 scopus 로고    scopus 로고
    • Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo
    • Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, et al. Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo. Cell Death Differ 19:871-881.
    • Cell Death Differ , vol.19 , pp. 871-881
    • Raimondi, L.1    Ciarapica, R.2    De Salvo, M.3    Verginelli, F.4    Gueguen, M.5    Martini, C.6    De Sio, L.7    Cortese, G.8    Locatelli, M.9    Dang, T.P.10
  • 43
  • 44
    • 0034162714 scopus 로고    scopus 로고
    • Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
    • Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J, Feramisco JR, Karin M, Wang JY. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev 2000, 14:574-584.
    • (2000) Genes Dev , vol.14 , pp. 574-584
    • Puri, P.L.1    Wu, Z.2    Zhang, P.3    Wood, L.D.4    Bhakta, K.S.5    Han, J.6    Feramisco, J.R.7    Karin, M.8    Wang, J.Y.9
  • 45
    • 0035021913 scopus 로고    scopus 로고
    • Subcellular localization of the steroid receptor coactivators (SRCs) and MEF2 in muscle and rhabdomyosarcoma cells
    • Chen SL, Wang SC, Hosking B, Muscat GE. Subcellular localization of the steroid receptor coactivators (SRCs) and MEF2 in muscle and rhabdomyosarcoma cells. Mol Endocrinol 2001, 15:783-796.
    • (2001) Mol Endocrinol , vol.15 , pp. 783-796
    • Chen, S.L.1    Wang, S.C.2    Hosking, B.3    Muscat, G.E.4
  • 47
    • 33746228132 scopus 로고    scopus 로고
    • Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10
    • Chang S, Young BD, Li S, Qi X, Richardson JA, Olson EN. Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 2006, 126:321-334.
    • (2006) Cell , vol.126 , pp. 321-334
    • Chang, S.1    Young, B.D.2    Li, S.3    Qi, X.4    Richardson, J.A.5    Olson, E.N.6
  • 50
    • 33846139305 scopus 로고    scopus 로고
    • Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation
    • Haberland M, Arnold MA, McAnally J, Phan D, Kim Y, Olson EN. Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation. Mol Cell Biol 2007, 27:518-525.
    • (2007) Mol Cell Biol , vol.27 , pp. 518-525
    • Haberland, M.1    Arnold, M.A.2    McAnally, J.3    Phan, D.4    Kim, Y.5    Olson, E.N.6


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