-
1
-
-
0344171979
-
Common musculoskeletal tumors of childhood and adolescence
-
Arndt CA, Crist WM. Common musculoskeletal tumors of childhood and adolescence. N Engl J Med 1999:341:342-352.
-
(1999)
N Engl J Med
, vol.341
, pp. 342-352
-
-
Arndt, C.A.1
Crist, W.M.2
-
2
-
-
13344286225
-
Treatment for childhood rhabdomyosar- coma: the cost of cure
-
Stevens MC. Treatment for childhood rhabdomyosar- coma: the cost of cure. Lancet Oncol 2005;6:77-84.
-
(2005)
Lancet Oncol
, vol.6
, pp. 77-84
-
-
Stevens, M.C.1
-
3
-
-
0028364374
-
Fusion of PAX7 to FTCHR by the variant t(l.;1.3)(p36;ql.4) translocation in alveolar rhabdomyosarcoma
-
Davis RJ, D'Cruz CM, LoveU MA, Biegel JA, Barr FG. Fusion, of PAX7 to FTCHR by the variant t(l.;1.3)(p36;ql.4) translocation in alveolar rhabdomyosarcoma. Cancer Res 1994;54:2869-2872
-
(1994)
Cancer Res
, vol.54
, pp. 2869-2872
-
-
Davis, R.J.1
D'Cruz, C.M.2
Lovell, M.A.3
Biegel, J.A.4
Barr, F.G.5
-
4
-
-
0035860134
-
Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyo- sarcoma: a reproducible predictor of outcome?
-
Anderson J, Gordon T, McManus A, et al. Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyo- sarcoma: a reproducible predictor of outcome? Br J Cancer 2001;85:831-835.
-
(2001)
Br J Cancer
, vol.85
, pp. 831-835
-
-
Anderson, J.1
Gordon, T.2
McManus, A.3
-
5
-
-
7544243041
-
Alveolar rhabdomyosarco- mas in conditional Pax3:Fkhr mice: cooperaüvity of Ink4a/ARF and Trp53 loss of function.
-
Keller C, Arenklel BR, Coffin. CM, El-Bardeesy N, DePinho RA, Capecchi MR. Alveolar rhabdomyosarco- mas in conditional Pax3:Fkhr mice: cooperaüvity of Ink4a/ARF and Trp53 loss of function. Genes Dev 2004; 18:2614-2626
-
(2004)
Genes Dev
, vol.18
, pp. 2614-2626
-
-
Keller, C.1
Arenklel, B.R.2
Coffin, C.M.3
El-Bardeesy, N.4
DePinho, R.A.5
Capecchi, M.R.6
-
6
-
-
24744454198
-
New genetic tactics to model alveolar rhabdomyosarcoma in the mouse
-
Keller C, Capecchl MR. New genetic tactics to model alveolar rhabdomyosarcoma in the mouse. Cancer Res 2005;65:7530-7532.
-
(2005)
Cancer Res
, vol.65
, pp. 7530-7532
-
-
Keller, C.1
Capecchl, M.R.2
-
7
-
-
7544235883
-
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin
-
Keller C, Hansen. MS, Coffin CM, Capecchl MR. Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev 2004;18:2608-2613.
-
(2004)
Genes Dev
, vol.18
, pp. 2608-2613
-
-
Keller, C.1
Hansen., M.S.2
Coffin, C.M.3
Capecchl, M.R.4
-
8
-
-
4143150844
-
Gene expression, signatures Identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translo- cation fusing PAX3 to NCOAl
-
Wachtel M, DettUng M, Koscielniak E, et al. Gene expression, signatures Identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translo- cation fusing PAX3 to NCOAl. Cancer Res 2004:64: 5539-5545
-
(2004)
Cancer Res
, vol.64
, pp. 5539-5545
-
-
Wachtel, M.1
Dettling, M.2
Koscielniak, E.3
-
9
-
-
34249781385
-
Global gene expression, profiling of PAX-FKHR fusion-positive alve- olar and PAX-FKHR fusion-negative embryonal rhabdo- myosarcomas
-
Lae M, Ahn EH, Mercado GE, et al. Global gene expression, profiling of PAX-FKHR fusion-positive alve- olar and PAX-FKHR fusion-negative embryonal rhabdo- myosarcomas. J Pathol 2007;212:143-151
-
(2007)
J Pathol
, vol.212
, pp. 143-151
-
-
Lae, M.1
Ahn, E.H.2
Mercado, G.E.3
-
10
-
-
25844483990
-
Variations in. gene expression, among different types of human skeletal muscle
-
Kang PB, Kho AT, Sanoudou D, et al. Variations in. gene expression, among different types of human skeletal muscle. Muscle Nerve 2005;32:483-491
-
(2005)
Muscle Nerve
, vol.32
, pp. 483-491
-
-
Kang, P.B.1
Kho, A.T.2
Sanoudou, D.3
-
11
-
-
0036823748
-
A web- accessible complete transcriptome of normal human and DMD muscle
-
SUPPL.:S125-S141
-
Bakay M, Zhao P, Chen J, Hoffman EP. A web- accessible complete transcriptome of normal human and DMD muscle. Neuromuscul Disord 2002; 12 Suppl 1: S125-41.
-
(2002)
Neuromuscul Disord
, vol.12
, Issue.1
-
-
Bakay, M.1
Zhao, P.2
Chen, J.3
Hoffman, E.P.4
-
12
-
-
3042738138
-
Kaposi sarcoma herpesvlrus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression, in Kaposi sarcoma
-
Wang HW, Trotter MW, Lagos D, et al. Kaposi sarcoma herpesvlrus-induced cellular reprogramming contributes to the lymphatic endothelial gene expres- sion, in Kaposi sarcoma. Nat Genet 2004;36:687-693.
-
(2004)
Nat Genet
, vol.36
, pp. 687-693
-
-
Wang, H.W.1
Trotter, M.W.2
Lagos, D.3
-
14
-
-
51649092873
-
Molecular characterization, of the pediatric preclinical, testing panel
-
Neale G, Su X, Morton CL, et al. Molecular characterization, of the pediatric preclinical, testing panel. Clin Cancer Res 2008;14:4572-4583.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4572-4583
-
-
Neale, G.1
Su, X.2
Morton, C.L.3
-
15
-
-
45349086509
-
Conditional mouse osteosarcoma, dependent on. p53 loss and potentiated by loss of Rb, mimics the human disease
-
Walkley CR, Qudsi R, Sankaran VG, et al. Conditional mouse osteosarcoma, dependent on. p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev 2008;22:1662-1676.
-
(2008)
Genes Dev
, vol.22
, pp. 1662-1676
-
-
Walkley, C.R.1
Qudsi, R.2
Sankaran, V.G.3
-
16
-
-
33750543972
-
A novel somatic mouse model to survey tumorigenic poten- tial applied to the Hedgehog pathway
-
Mao J, Ligon KL, Rakhlin. EY, et al. A novel somatic mouse model to survey tumorigenic poten- tial applied to the Hedgehog pathway. Cancer Res 2006;66:10171-10178
-
(2006)
Cancer Res
, vol.66
, pp. 10171-10178
-
-
Mao, J.1
Ligon, K.L.2
Rakhlin, E.Y.3
-
17
-
-
33646356739
-
F-box protein Skp2: a novel transcriptional target of E2F
-
Zhang L, Wang C. F-box protein Skp2: a novel transcriptional target of E2F. Oncogene 2006;25:2615-2627
-
(2006)
Oncogene
, vol.25
, pp. 2615-2627
-
-
Zhang, L.1
Wang, C.2
-
18
-
-
55249083566
-
PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma
-
Taniguchi E, Nishijo K, McCleish AT, et al. PDGFR-A. is a therapeutic target in alveolar rhabdomyosarcoma. Oncogene 2008;27:6550-6560.
-
(2008)
Oncogene
, vol.27
, pp. 6550-6560
-
-
Taniguchi, E.1
Nishijo, K.2
McCleish, A.T.3
-
19
-
-
29944432793
-
Pax.3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells
-
Relaix F, Montarras D, Zaffran S, et al. Pax.3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol 2006;172:91-102.
-
(2006)
J Cell Biol
, vol.172
, pp. 91-102
-
-
Relaix, F.1
Montarras, D.2
Zaffran, S.3
-
20
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005:102:15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
21
-
-
34249905448
-
Effects of RAS on. the genesis of embryonal,rhabdomyosarcoma
-
Ungenau DM, Keefe MD, Storer NY, et al. Effects of RAS on. the genesis of embryonal, rhabdomyosarcoma. Genes Dev 2007:21:1382-1395.
-
(2007)
Genes Dev
, vol.21
, pp. 1382-1395
-
-
Ungenau, D.M.1
Keefe, M.D.2
Storer, N.Y.3
-
22
-
-
34347219009
-
Metagene projection for cross-platform, cross-species characterization of global, transcriptional, states
-
Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. Metagene projection for cross-platform, cross-species characterization of global, transcriptional, states. Proc Natl Acad Sd USA 2007;104:5959-5964
-
(2007)
Proc Natl Acad Sd USA
, vol.104
, pp. 5959-5964
-
-
Tamayo, P.1
Scanfeld, D.2
Ebert, B.L.3
Gillette, M.A.4
Roberts, C.W.5
Mesirov, J.P.6
-
23
-
-
33746895755
-
Identification, of a PAX- FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas
-
Davicioni E, Finckenstein FG, Shahbazian V, Buckley JD, Triche TJ, Anderson MJ. Identification, of a PAX- FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas. Cancer Res 2006;66:6936-6946
-
(2006)
Cancer Res
, vol.66
, pp. 6936-6946
-
-
Davicioni, E.1
Finckenstein, F.G.2
Shahbazian, V.3
Buckley, J.D.4
Triche, T.J.5
Anderson, M.J.6
-
25
-
-
0037414791
-
PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kipl, a potential role for elevated Skp2 expression
-
Zhang L, Wang C. PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kipl, a potential role for elevated Skp2 expression. J Biol Chem 2003;278:27-36.
-
(2003)
J Biol Chem
, vol.278
, pp. 27-36
-
-
Zhang, L.1
Wang, C.2
-
26
-
-
0036196163
-
Identification of target genes regulated by PAX3 and PAX3-FKHR in. embryogenesis and alveolar rhabdomyosarcoma
-
Barber TD, Barber MC, Tomescu O, Barr FG, Ruben S, Friedman TB. Identification of target genes regulated by PAX3 and PAX3-FKHR in. embryogenesis and alveolar rhabdomyosarcoma. Genomics 2002;79:278-284
-
(2002)
Genomics
, vol.79
, pp. 278-284
-
-
Barber, T.D.1
Barber, M.C.2
Tomescu, O.3
Barr, F.G.4
Ruben, S.5
Friedman, T.B.6
-
27
-
-
34247369851
-
A homeo-paired domain-binding motif directs MyfS expression in progenitor cells of limb muscle
-
Buchberger A, Freitag D, Arnold HH. A homeo-paired domain-binding motif directs MyfS expression in progenitor cells of limb muscle. Development 2007;134: 1171-80.
-
(2007)
Development
, vol.134
, pp. 1171-1180
-
-
Buchberger, A.1
Freitag, D.2
Arnold, H.H.3
-
28
-
-
33645216339
-
Cul4A and DDBl associate with Skp2 to target p27Kip.l for proteolysis involving the COP9 signalosome
-
Bondar T1 Kalmina A1 Khair L1 et al. Cul4A and DDBl associate with Skp2 to target p27Kip.l for proteolysis involving the COP9 signalosome. MoI Cell Biol 2006:26: 2531.-2539.
-
(2006)
MoI Cell Biol
, vol.26
, pp. 2531-2539
-
-
Bondar, T.1
Kalmina, A.2
Khair, L.3
-
29
-
-
33745434781
-
p53 downregulat.es its activating vaccinia-related kinase 1, forming a new autoregulatory loop
-
Valbuena A, Vega FM, Blanco S, Lazo PA. p53 downregulat.es its activating vaccinia-related kinase 1, forming a new autoregulatory loop. MoI. Cell Biol 2006; 26:4782-4793.
-
(2006)
MoI. Cell Biol
, vol.26
, pp. 4782-4793
-
-
Valbuena, A.1
Vega, F.M.2
Blanco, S.3
Lazo, P.A.4
-
30
-
-
34548058372
-
Pharmacological and functional comparison of the polo-like kinase famUy: insight into inhibitor and substrate specificity.
-
Johnson EF, Stewart. KD, Woods KW Giranda VI, Luo Y. Pharmacological and functional comparison of the polo-like kinase famUy: insight into inhibitor and substrate specificity. Biochemistry 2007;46:9551-9563.
-
(2007)
Biochemistry
, vol.46
, pp. 9551-9563
-
-
Johnson, E.F.1
Stewart, K.D.2
Woods, K.W.3
Giranda, V.I.4
Luo, Y.5
-
31
-
-
37249023281
-
VX-680 inhibits Aurora A and Aurora B kinase activity in human cells.
-
Tyler RK, Shpiro N, Marquez R, Eyers PA. VX-680 inhibits Aurora A and Aurora B kinase activity in human ceUs. CeU Cycle 2007;6:2846-2854
-
(2007)
Cell Cycle
, vol.6
, pp. 2846-2854
-
-
Tyler, R.K.1
Shpiro, N.2
Marquez, R.3
Eyers, P.A.4
-
32
-
-
84888544277
-
Comparative expression, profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR
-
Ebauer M, Wachtel M, Niggli FK, Schäfer BW. Comparative expression, profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR. Oncogene 2007:104: 5959-5964.
-
(2007)
Oncogene
, vol.104
, pp. 5959-5964
-
-
Ebauer, M.1
Wachtel, M.2
Niggli, F.K.3
Schäfer, B.W.4
-
33
-
-
16244385890
-
Cell-type-spedflc regulation, of distinct sets of gene targets by Pax3 and Pax3/FKHR.
-
Begum S, Emani N, Cheung A, Wilkins O, Der S, Hamel PA. Cell-type-spedflc regulation, of distinct sets of gene targets by Pax3 and Pax3/FKHR. Oncogene 2005; 24:1860-1872.
-
(2005)
Oncogene
, vol.24
, pp. 1860-1872
-
-
Begum, S.1
Emani, N.2
Cheung, A.3
Wilkins, O.4
Der, S.5
Hamel, P.A.6
-
34
-
-
3543083872
-
Inducible short- term and. stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression
-
Tomescu O, XIa SJ, Strezlecki D, et al. Inducible short- term and. stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression. Lab Invest 2004: 84:1060-1070
-
(2004)
Lab Invest
, vol.84
, pp. 1060-1070
-
-
Tomescu, O.1
XIa, S.J.2
Strezlecki, D.3
-
35
-
-
0031861728
-
Tumor- specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor a receptor.
-
Epstein JA, Song B, Lakkis M, Wang C. Tumor- specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor a receptor. MoI Cell Biol 1.998:18:411.8-30
-
MoI Cell Biol
, vol.199
, Issue.18
, pp. 4118-4130
-
-
Epstein, J.A.1
Song, B.2
Lakkis, M.3
Wang, C.4
-
36
-
-
33646382114
-
Gene expression, profiling Identifies potential, relevant genes in alveolar rhabdomyosarcoma pathogenesis and dis- criminates PAX3-FKITR positive and negative tumors
-
De Pitta C, Tombolan L, Albiero G, et al. Gene expression, profiling Identifies potential, relevant genes in alveolar rhabdomyosarcoma pathogenesis and dis- criminates PAX3-FKITR positive and negative tumors. Int J Cancer 2006;118:2772-2781
-
(2006)
Int J Cancer
, vol.118
, pp. 2772-2781
-
-
De Pitta, C.1
Tombolan, L.2
Albiero, G.3
-
37
-
-
0033539498
-
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion, oncogene
-
Khan J, Bittner ML, Saal LH, et al. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion, oncogene. Proc Natl Acad Sei USA 1999;96:13264-13269
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13264-13269
-
-
Khan, J.1
Bittner, M.L.2
Saal, L.H.3
-
38
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and (J-TrCP: tipping the scales of cancer
-
Frescas D1 Pagano M1 Deregulated proteolysis by the F-box proteins SKP2 and (J-TrCP: tipping the scales of cancer. Nat Rev 2008;8:438-49.
-
(2008)
Nat Rev
, vol.8
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
39
-
-
13444252337
-
Skp2 inhibits FOXOl in tumor suppression through ubiquitin-medi- ated degradation
-
Huang H, Regan KM, Wang F1 et al. Skp2 inhibits FOXOl in tumor suppression through ubiquitin-medi- ated degradation. Proc Natl Acad Sd U S A 2005;102: .1649-1654
-
(2005)
Proc Natl Acad Sd U S A
, vol.102
, pp. 1649-1654
-
-
Huang, H.1
Regan, K.M.2
Wang, F.3
-
40
-
-
0029154584
-
Wild type PAX3 protein and the PAX3- FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains
-
Bennicelli JL1 Fredericks WJ1 Wilson RB1 Rauscher FJ ill, Barr FG. Wild type PAX3 protein and the PAX3- FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains. Oncogene 1995;11:119-130
-
(1995)
Oncogene
, vol.11
, pp. 119-130
-
-
Bennicelli, J.L.1
Fredericks, W.J.2
Wilson, R.B.3
Rauscher III, F.J.4
Barr, F.G.5
-
41
-
-
0037160050
-
Phosphorylation of serine 256 suppresses transactivatlon by FKHR (FOXOl) by multiple mechanisms. Direct and indirect effects on nudear/cytoplasmlc shuttling and DNA binding
-
Zhang X, Gan L, Pan. H, et al. Phosphorylation of serine 256 suppresses transactivatlon by FKHR (FOXOl) by multiple mechanisms. Direct and indirect effects on nudear/cytoplasmlc shuttling and DNA binding. J Biol Chem. 2002;277:45276-45284.
-
(2002)
J Biol Chem.
, vol.277
, pp. 45276-45284
-
-
Zhang, X.1
Gan, L.2
Pan, H.3
-
42
-
-
31344473376
-
Practical vessel imaging by computed tomography in live transgenic mouse models for human tumors
-
Kindlmann GL, Weinstein DM, Jones GM, John- son CR, Capecchi MR, Keller C. Practical vessel imaging by computed tomography in live transgenic mouse models for human tumors. MoI Imaging 2005;4: 417-24.
-
(2005)
MoI Imaging
, vol.4
, pp. 417-424
-
-
Kindlmann, G.L.1
Weinstein, D.M.2
Jones, G.M.3
Johnson, C.R.4
Capecchi, M.R.5
Keller, C.6
-
43
-
-
44149091042
-
Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG1 KOS-1022) by the pediatric predinical testing program
-
Smith MA, Morton CL, Phelps DA, et al. Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG1 KOS-1022) by the pediatric predinical testing program. Pediatr Blood Cancer 2008;51:34-41.
-
(2008)
Pediatr Blood Cancer
, vol.51
, pp. 34-41
-
-
Smith, M.A.1
Morton, C.L.2
Phelps, D.A.3
-
44
-
-
53049083206
-
Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations
-
Ren YX, Finckenstein FG, Abdueva DA, et al. Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res 2008;68:6587-6597
-
(2008)
Cancer Res
, vol.68
, pp. 6587-6597
-
-
Ren, Y.X.1
Finckenstein, F.G.2
Abdueva, D.A.3
-
45
-
-
34447249881
-
The pediatric preclinical testing program: description of models and early testing results
-
Houghton. PJ, Morton CL, Tucker C1 et al. The pediatric preclinical testing program: description of models and early testing results. Pediatr Blood Cancer 2007;49:928-940.
-
(2007)
Pediatr Blood Cancer
, vol.49
, pp. 928-940
-
-
Houghton, P.J.1
Morton, C.L.2
Tucker, C.3
-
46
-
-
0036896670
-
Testing of new agents in childhood cancer preclinical models:meeting summary
-
Houghton PJ, Adamson PC, Blaney S, et al. Testing of new agents in childhood cancer preclinical models: meeting summary. Clin Cancer Res 2002;8:3646-3657
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3646-3657
-
-
Houghton, P.J.1
Adamson, P.C.2
Blaney, S.3
|