Regulation on RhoA in vascular smooth muscle cells under inflammatory stimulation proposes a novel mechanism mediating the multiple-beneficial action of acetylsalicylic acid

Inflammation

Volumn 36, Issue 6, 2013, Pages 1403-1414

  Li, Dong Bo ^a   Yang, Guo Jie ^a   Xu, Hong Wei ^b   Fu, Zhi Xuan ^c   Wang, Shan Wei ^d   Hu, Shen Jiang ^e  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HENAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c ZHEJIANG CANCER HOSPITAL   (China)

^d XI'AN MEDICAL UNIVERSITY   (China)

^e ZHEJIANG UNIVERSITY   (China)

Author keywords

aspirin; iNOS; phosphorylation; RhoA; vascular smooth muscle cells

Indexed keywords

ACETYLSALICYLIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; INFLAMMATION; MALE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; ASPIRIN; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; INFLAMMATION; MALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RHOA GTP-BINDING PROTEIN;

EID: 84888204692     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9680-5     Document Type: Article

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