-
1
-
-
84869176553
-
Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures
-
Eimer S, Dugay F, Airiau K, et al. Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures. Neuro Oncol. 2012;14:1441-1451.
-
(2012)
Neuro Oncol
, vol.14
, pp. 1441-1451
-
-
Eimer, S.1
Dugay, F.2
Airiau, K.3
-
2
-
-
84867590025
-
Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling
-
Pratap A, Singh S, Mundra V, et al. Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling. J Drug Target. 2012;20:770-782.
-
(2012)
J Drug Target
, vol.20
, pp. 770-782
-
-
Pratap, A.1
Singh, S.2
Mundra, V.3
-
3
-
-
84864701350
-
Micellar delivery of cyclopamine and gefitinib for treating pancreatic cancer
-
Epub July 23
-
Chitkara D, Singh S, Kumar V, et al. Micellar delivery of cyclopamine and gefitinib for treating pancreatic cancer. Mol Pharm. Epub July 23, 2012.
-
(2012)
Mol Pharm
-
-
Chitkara, D.1
Singh, S.2
Kumar, V.3
-
4
-
-
84861352086
-
Hedgehog pathway as a drug target: Smoothened inhibitors in development
-
Lin TL, Matsui W. Hedgehog pathway as a drug target: Smoothened inhibitors in development. Onco Targets Ther. 2012;5:47-58.
-
(2012)
Onco Targets Ther
, vol.5
, pp. 47-58
-
-
Lin, T.L.1
Matsui, W.2
-
5
-
-
79960498438
-
Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling
-
Fan Q, Gu D, He M, et al. Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling. Chin J Cancer. 2011;30: 472-481.
-
(2011)
Chin J Cancer
, vol.30
, pp. 472-481
-
-
Fan, Q.1
Gu, D.2
He, M.3
-
6
-
-
84881547712
-
TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling
-
Ibuki N, Ghaffari M, Pandey M, et al. TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling. Int J Cancer. 2013;133:1955-1966.
-
(2013)
Int J Cancer
, vol.133
, pp. 1955-1966
-
-
Ibuki, N.1
Ghaffari, M.2
Pandey, M.3
-
7
-
-
84863111668
-
Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway
-
Singh S, Chitkara D, Mehrazin R, Behrman SW, Wake RW, Mahato RI. Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway. PloS One. 2012;7:e40021.
-
(2012)
PloS One
, vol.7
-
-
Singh, S.1
Chitkara, D.2
Mehrazin, R.3
Behrman, S.W.4
Wake, R.W.5
Mahato, R.I.6
-
8
-
-
83555176260
-
Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells
-
Zhou Y, Yang J, Kopeček J. Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells. Biomaterials. 2012;33:1863-1872.
-
(2012)
Biomaterials
, vol.33
, pp. 1863-1872
-
-
Zhou, Y.1
Yang, J.2
Kopeček, J.3
-
9
-
-
79953702542
-
Hedgehog signaling and therapeutics in pancreatic cancer
-
Kelleher FC. Hedgehog signaling and therapeutics in pancreatic cancer. Carcinogenesis. 2011;32:445-451.
-
(2011)
Carcinogenesis
, vol.32
, pp. 445-451
-
-
Kelleher, F.C.1
-
10
-
-
77956269276
-
Expression and regulation of hedgehog signaling pathway in pancreatic cancer
-
Yang Y, Tian X, Xie X, Zhuang Y, Wu W, Wang W. Expression and regulation of hedgehog signaling pathway in pancreatic cancer. Langenbecks Arch Surg. 2010;395:515-525.
-
(2010)
Langenbecks Arch Surg
, vol.395
, pp. 515-525
-
-
Yang, Y.1
Tian, X.2
Xie, X.3
Zhuang, Y.4
Wu, W.5
Wang, W.6
-
11
-
-
84880196103
-
Pathways to breast cancer recurrence
-
2013
-
Ahmad A. Pathways to breast cancer recurrence. ISRN Oncol. 2013;2013:290568.
-
(2013)
ISRN Oncol
, pp. 290568
-
-
Ahmad, A.1
-
12
-
-
84878297133
-
Therapeutic targets in triple negative breast cancer
-
O'Toole SA, Beith JM, Millar EK, et al. Therapeutic targets in triple negative breast cancer. J Clin Pathol. 2013;66(6):530-542.
-
(2013)
J Clin Pathol
, vol.66
, Issue.6
, pp. 530-542
-
-
O'Toole, S.A.1
Beith, J.M.2
Millar, E.K.3
-
13
-
-
84875417726
-
The hedgehog pathway in breast cancer
-
Ali SA. The hedgehog pathway in breast cancer. Chin J Cancer Res. 2012;24:261-262.
-
(2012)
Chin J Cancer Res
, vol.24
, pp. 261-262
-
-
Ali, S.A.1
-
14
-
-
84875805562
-
The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy
-
Hui M, Cazet A, Nair R, Watkins DN, O'Toole SA, Swarbrick A. The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy. Breast Cancer Res. 2013;15:203.
-
(2013)
Breast Cancer Res
, vol.15
, pp. 203
-
-
Hui, M.1
Cazet, A.2
Nair, R.3
Watkins, D.N.4
O'Toole, S.A.5
Swarbrick, A.6
-
16
-
-
79957989939
-
Drug discovery approaches to target Wnt signaling in cancer stem cells
-
Curtin JC, Lorenzi MV. Drug discovery approaches to target Wnt signaling in cancer stem cells. Oncotarget. 2010;1:563-577.
-
(2010)
Oncotarget
, vol.1
, pp. 563-577
-
-
Curtin, J.C.1
Lorenzi, M.V.2
-
17
-
-
84863955787
-
Shared signaling pathways in normal and breast cancer stem cells
-
Malhotra GK, Zhao X, Band H, Band V. Shared signaling pathways in normal and breast cancer stem cells. J Carcinog. 2011;10:38.
-
(2011)
J Carcinog
, vol.10
, pp. 38
-
-
Malhotra, G.K.1
Zhao, X.2
Band, H.3
Band, V.4
-
19
-
-
84862565810
-
Cancer stem cells and novel targets for antitumor strategies
-
Prud'homme GJ. Cancer stem cells and novel targets for antitumor strategies. Curr Pharm Des. 2012;18:2838-2849.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 2838-2849
-
-
Prud'homme, G.J.1
-
20
-
-
84860709668
-
Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway
-
Lu JT, Zhao WD, He W, Wei W. Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway. Acta Pharmacol Sin. 2012;33:691-700.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 691-700
-
-
Lu, J.T.1
Zhao, W.D.2
He, W.3
Wei, W.4
-
21
-
-
84863230555
-
The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells
-
Shi Y, Fu X, Hua Y, Han Y, Lu Y, Wang J. The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells. PloS One. 2012;7:e33358.
-
(2012)
PloS One
, vol.7
-
-
Shi, Y.1
Fu, X.2
Hua, Y.3
Han, Y.4
Lu, Y.5
Wang, J.6
-
22
-
-
84855804948
-
Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells
-
Wang X, Venugopal C, Manoranjan B, et al. Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells. Oncogene. 2012;31:187-199.
-
(2012)
Oncogene
, vol.31
, pp. 187-199
-
-
Wang, X.1
Venugopal, C.2
Manoranjan, B.3
-
23
-
-
84875804419
-
GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation
-
Goel HL, Pursell B, Chang C, et al. GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013;5:488-508.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 488-508
-
-
Goel, H.L.1
Pursell, B.2
Chang, C.3
-
24
-
-
84859074645
-
Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases
-
Das S, Tucker JA, Khullar S, Samant RS, Shevde LA. Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases. PloS One. 2012;7:e34374.
-
(2012)
PloS One
, vol.7
-
-
Das, S.1
Tucker, J.A.2
Khullar, S.3
Samant, R.S.4
Shevde, L.A.5
-
25
-
-
84872491549
-
Developmental signaling pathways in cancer stem cells of solid tumors
-
Karamboulas C, Ailles L. Developmental signaling pathways in cancer stem cells of solid tumors. Biochim Biophys Acta. 2013;1830: 2481-2495.
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 2481-2495
-
-
Karamboulas, C.1
Ailles, L.2
-
26
-
-
33748469128
-
Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells
-
Shafaee Z, Schmidt H, Du W, Posner M, Weichselbaum R. Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells. Cancer Chemother Pharmacol. 2006;58:765-770.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 765-770
-
-
Shafaee, Z.1
Schmidt, H.2
Du, W.3
Posner, M.4
Weichselbaum, R.5
-
28
-
-
70350534843
-
Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Katoh Y, Katoh M. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr Mol Med. 2009;9:873-886.
-
(2009)
Curr Mol Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
|